Alien macrocrustaceans in freshwater ecosystems in the eastern part of Flanders (Belgium)

Biological invasions of freshwater macroinvertebrates are gaining more and more interest because the ecological and economical impact of some of these species is high. Since crustacean taxa appear to be successful groups invading new areas, an inventory of the macrocrustaceans in Flanders was made. At least 22 freshwater macrocrustacean species have been reported from Flemish water bodies. A detailed study of six canals, one small artificial watercourse and one natural river in the eastern part of Flanders revealed that invaders such as Dikerogammarus villosus, Gammarus tigrinus and Chelicorophium curvispinum are already quite common. Especially D. villosus is currently rapidly expanding and has a serious impact on native and other exotic gammarid species. Based on observations in neighbouring countries, several additional species are expected to arrive in the near future. A follow-up of the alien species together with a monitoring scheme to detect new incoming species is valuable to estimate the size of the problem and to be able to closely follow their ecological and economical impact

First-year French medical students consume antidepressants and anxiolytics while second-years consume non-medical drugs.

International audienc

Recent modeling for the ITER ion cyclotron range of frequency antennas with the TOPICA code

This paper documents the analysis of the ITER ion cyclotron resonance heating (ICRF) launcher using the TOPICA code, throughout recent years' design activities. The ability to simulate the detailed geometry of an ICRF antenna in front of a realistic plasma and to obtain the antenna input parameters, the electric currents on conductors and the radiated field distribution next to the antenna is of significant importance to evaluate and predict the overall system performances. Starting from a reference geometry, we first investigated the impact of some geometrical and numerical factors, such as the Faraday Screen geometry or the mesh quality. Then a final geometry was the object of a comprehensive analysis, varying the working frequency, the plasma conditions and the poloidal and toroidal phasings between the feeding lines. The performance of the antenna has been documented in terms of input parameters, power coupled to plasma and electric fields. Eventually, the four-port junction has also been included in TOPICA models

ESGAP inventory of target indicators assessing antibiotic prescriptions: A cross-sectional survey

Background A variety of indicators is commonly used to monitor antibiotic prescriptions as part of national antimicrobial stewardship (AMS) programmes. Objectives To make an inventory of indicators that assess antibiotic prescriptions and are linked to specific targets and incentives, at a national level. Methods A cross-sectional survey (three-item questionnaire) was conducted in 2017 among all ESGAP (ESCMID Study Group for Antimicrobial stewardshiP) members, coming from 23 European countries and 16 non-European countries. Results Almost all (20/23, 87%) European countries belonging to the ESGAP network participated, as well as one non-European country. Computerized systems routinely linking antibiotic prescriptions to clinical diagnoses were reported for only two countries (Turkey and Croatia). Only 6/21 (29%) countries had national indicators with both clear targets and incentives (Bulgaria, Croatia, France, the Netherlands, Norway and Portugal). We identified a total of 21 different indicators used in these countries, 16 concerning inpatients (9 quality indicators and 7 quantity metrics) and 8 concerning outpatients (all quantity metrics); some indicators were used in both settings. Three types of incentives were used: financing mechanism, hospitals' accreditation and public reporting. Some respondents reported that such indicators with both clear targets and incentives were used at a regional level in their country (e.g. Andalusia in Spain and England in the UK). Conclusions National indicators, with clear targets and incentives, are not commonly used in Europe and we observed wide variations between countries regarding the selected indicators, the units of measure and the chosen targets

Management of Hepatic Angiomyolipoma

Preoperative diagnosis of hepatic angiomyolipoma is difficult, and the treatment for it remains controversial. The aim of this study is to review our experience in the treatment of hepatic angiomyolipoma and to propose a treatment strategy for this disease. We retrospectively collected the clinical, imaging, and pathological features of patients with hepatic angiomyolipoma. Immunohistochemical studies with antibodies for HMB-45, actin, S-100, cytokeratin, vimentin, and c-kit were performed. Treatment experience and long-term follow-up results are summarized. During a period of 9 years, 10 patients with hepatic angiomyolipoma were treated at our hospital. There was marked female predominance (nine patients). Nine patients received surgical resection without complications. One patient received nonoperative management with biopsy and follow-up. One patient died 11 months after surgery because of recurrent disease. We propose all symptomatic patients should receive surgical resection for hepatic angiomyolipoma. Conservative management with close follow-up is suggested in patients with asymptomatic tumors and meet the following criteria: (1) tumor size smaller than 5 cm, (2) angiomyolipoma proved through fine needle aspiration biopsy, (3) patients with good compliance, and (4) not a hepatitis virus carrier