11 research outputs found

    InnoChain: распределенный реестр для индустриального применения с формальной верификацией на всех уровнях реализации

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    The extent of formal verification methods applied to industrial projects has always been limited. The proliferation of distributed ledger systems (DLS), also known as blockchain, is rapidly changing the situation. Since the main area of DLSs' application is the automation of financial transactions, the properties of predictability and reliability are critical for implementing such systems. The actual behavior of the DLS is determined by the chosen consensus protocol, which properties require strict specification and formal verification. Formal specification and verification of the consensus protocol is necessary but not sufficient. It is required to ensure that the software implementation of the DLS nodes complies with this protocol. The verified software implementation of the protocol must run on a fairly reliable operating system. The so-called “smart contracts”, which are an important part of the applied implementations of specific business processes based on DLSs, must be verifiable as well. In this paper, we describe an ongoing industrial project that will result in a DLS verified at least at the four technological levels described above. We then share our experience with the formal specification and verification of HotStuff, a leader-based fault-tolerant protocol that ensures reaching distributed consensus in the presence of Byzantine processes.Степень применения методов формальной верификации в индустриальных проектах всегда была ограничена. Распространение систем распределенного реестра (СРР), известных также как блокчейн, быстро меняет ситуацию. Поскольку основной областью применения СРР является автоматизация финансовых транзакций, свойства предсказуемости и надежности являются критическими при реализации таких систем. Реальное поведение СРР определяется выбранным протоколом консенсуса, свойства которого нуждаются в строгой спецификации и формальной верификации. Формальная спецификация и верификация протокола консенсуса необходима, но недостаточна. Необходимо удостовериться, что программная реализация узлов СРР соответствует данному протоколу. Верифицированная программная реализация протокола должна запускаться на достаточно надежной операционной системе. Так называемые “умные контракт”, которые являются важной частью прикладных реализаций конкретных бизнес-процессов на основе СРР, также должны быть верифицируемы.В данной работе мы описываем реализующийся в настоящее время индустриальный проект, результатом которого станет СРР, верифицированная по меньшей мере на четырех описанных выше технологических уровнях. Мы также описываем наш опыт формальной спецификации и верификации протокола HotStuff - отказоустойчивого протокола для гарантированного достижения консенсуса в присутствии византийских процессов и лидера

    The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis

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    Background A growing body of research identifies the harmful effects that adverse childhood experiences (ACEs; occurring during childhood or adolescence; eg, child maltreatment or exposure to domestic violence) have on health throughout life. Studies have quantified such effects for individual ACEs. However, ACEs frequently co-occur and no synthesis of findings from studies measuring the effect of multiple ACE types has been done. Methods In this systematic review and meta-analysis, we searched five electronic databases for cross-sectional, case-control, or cohort studies published up to May 6, 2016, reporting risks of health outcomes, consisting of substance use, sexual health, mental health, weight and physical exercise, violence, and physical health status and conditions, associated with multiple ACEs. We selected articles that presented risk estimates for individuals with at least four ACEs compared with those with none for outcomes with sufficient data for meta-analysis (at least four populations). Included studies also focused on adults aged at least 18 years with a sample size of at least 100. We excluded studies based on high-risk or clinical populations. We extracted data from published reports. We calculated pooled odds ratios (ORs) using a random-effects model. Findings Of 11 621 references identified by the search, 37 included studies provided risk estimates for 23 outcomes, with a total of 253 719 participants. Individuals with at least four ACEs were at increased risk of all health outcomes compared with individuals with no ACEs. Associations were weak or modest for physical inactivity, overweight or obesity, and diabetes (ORs of less than two); moderate for smoking, heavy alcohol use, poor self-rated health, cancer, heart disease, and respiratory disease (ORs of two to three), strong for sexual risk taking, mental ill health, and problematic alcohol use (ORs of more than three to six), and strongest for problematic drug use and interpersonal and self-directed violence (ORs of more than seven). We identified considerable heterogeneity (I 2 of > 75%) between estimates for almost half of the outcomes. Interpretation To have multiple ACEs is a major risk factor for many health conditions. The outcomes most strongly associated with multiple ACEs represent ACE risks for the next generation (eg, violence, mental illness, and substance use). To sustain improvements in public health requires a shift in focus to include prevention of ACEs, resilience building, and ACE-informed service provision. The Sustainable Development Goals provide a global platform to reduce ACEs and their life-course effect on health. Funding Public Health Wales. © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licens

    InnoChain: a Distributed Ledger for Industry with Formal Verification on all Implementation Levels

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    The extent of formal verification methods applied to industrial projects has always been limited. The proliferation of distributed ledger systems (DLS), also known as blockchain, is rapidly changing the situation. Since the main area of DLSs' application is the automation of financial transactions, the properties of predictability and reliability are critical for implementing such systems. The actual behavior of the DLS is determined by the chosen consensus protocol, which properties require strict specification and formal verification. Formal specification and verification of the consensus protocol is necessary but not sufficient. It is required to ensure that the software implementation of the DLS nodes complies with this protocol. The verified software implementation of the protocol must run on a fairly reliable operating system. The so-called “smart contracts”, which are an important part of the applied implementations of specific business processes based on DLSs, must be verifiable as well. In this paper, we describe an ongoing industrial project that will result in a DLS verified at least at the four technological levels described above. We then share our experience with the formal specification and verification of HotStuff, a leader-based fault-tolerant protocol that ensures reaching distributed consensus in the presence of Byzantine processes

    Primary stroke prevention worldwide: translating evidence into action

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    Stroke is the second leading cause of death and the third leading cause of disability worldwide and its burden is increasing rapidly in low-income and middle-income countries, many of which are unable to face the challenges it imposes. In this Health Policy paper on primary stroke prevention, we provide an overview of the current situation regarding primary prevention services, estimate the cost of stroke and stroke prevention, and identify deficiencies in existing guidelines and gaps in primary prevention. We also offer a set of pragmatic solutions for implementation of primary stroke prevention, with an emphasis on the role of governments and population-wide strategies, including task-shifting and sharing and health system re-engineering. Implementation of primary stroke prevention involves patients, health professionals, funders, policy makers, implementation partners, and the entire population along the life course

    ILC Reference Design Report Volume 1 - Executive Summary

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    The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2s^-1. This report is the Executive Summary (Volume I) of the four volume Reference Design Report. It gives an overview of the physics at the ILC, the accelerator design and value estimate, the detector concepts, and the next steps towards project realization.The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2s^-1. This report is the Executive Summary (Volume I) of the four volume Reference Design Report. It gives an overview of the physics at the ILC, the accelerator design and value estimate, the detector concepts, and the next steps towards project realization

    ILC Reference Design Report Volume 4 - Detectors

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    This report, Volume IV of the International Linear Collider Reference Design Report, describes the detectors which will record and measure the charged and neutral particles produced in the ILC's high energy e+e- collisions. The physics of the ILC, and the environment of the machine-detector interface, pose new challenges for detector design. Several conceptual designs for the detector promise the needed performance, and ongoing detector R&D is addressing the outstanding technological issues. Two such detectors, operating in push-pull mode, perfectly instrument the ILC interaction region, and access the full potential of ILC physics.This report, Volume IV of the International Linear Collider Reference Design Report, describes the detectors which will record and measure the charged and neutral particles produced in the ILC's high energy e+e- collisions. The physics of the ILC, and the environment of the machine-detector interface, pose new challenges for detector design. Several conceptual designs for the detector promise the needed performance, and ongoing detector R&D is addressing the outstanding technological issues. Two such detectors, operating in push-pull mode, perfectly instrument the ILC interaction region, and access the full potential of ILC physics

    ILC Reference Design Report Volume 3 - Accelerator

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    The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2 s^-1. The complex includes a polarized electron source, an undulator-based positron source, two 6.7 km circumference damping rings, two-stage bunch compressors, two 11 km long main linacs and a 4.5 km long beam delivery system. This report is Volume III (Accelerator) of the four volume Reference Design Report, which describes the design and cost of the ILC.The International Linear Collider (ILC) is a 200-500 GeV center-of-mass high-luminosity linear electron-positron collider, based on 1.3 GHz superconducting radio-frequency (SCRF) accelerating cavities. The ILC has a total footprint of about 31 km and is designed for a peak luminosity of 2x10^34 cm^-2 s^-1. The complex includes a polarized electron source, an undulator-based positron source, two 6.7 km circumference damping rings, two-stage bunch compressors, two 11 km long main linacs and a 4.5 km long beam delivery system. This report is Volume III (Accelerator) of the four volume Reference Design Report, which describes the design and cost of the ILC
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