57 research outputs found

    Human-Likeness Indicator for Robot Posture Control and Balance

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    Similarly to humans, humanoid robots require posture control and balance to walk and interact with the environment. In this work posture control in perturbed conditions is evaluated as a performance test for humanoid control. A specific performance indicator is proposed: the score is based on the comparison between the body sway of the tested humanoid standing on a moving surface and the sway produced by healthy subjects performing the same experiment. This approach is here oriented to the evaluation of a human-likeness. The measure is tested using a humanoid robot in order to demonstrate a typical usage of the proposed evaluation scheme and an example of how to improve robot control on the basis of such a performance indicator scoreComment: 16 pages, 5 Figures. arXiv admin note: substantial text overlap with arXiv:2110.1439

    Visual search and visual working memory in patients with chronic focal cortical lesions

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    Visually guided behavior is known to involve temporo-parietal, inferotemporal, and prefrontal cortex and each of these areas appears to contribute to visual working memory. We explored the extent to which chronic lesions in one of these cortical areas affect visually guided oculomotor performance. We also explore whether possible impairments become more pronounced with increasing memory load. With this aim we recorded saccadic eye movements in 19 patients with a chronic focal postsurgical lesion in either temporo-parietal, inferior temporal or prefrontal cortex. Their results are compared to those of 19 age-matched volunteers. The subjects performed three different visual search tasks with increasing memory load: Instructed search, cue-guided search and memory-guided search. In addition, the latter task was performed with a short (1 s) and a long (6 s) delay. All tasks required the subjects to make a saccade to a single target presented together with one or three distractors. The results indicate that patients with inferotemporal lesions make the most task-related errors. Saccadic reaction times (SRTs) were significantly prolonged in patients with temporo-parietal and prefrontal lesions, but were unaffected in the patients with lesions in the inferotemporal cortex. The spatial accuracy of saccades was lowest in patients with temporo-parietal lesions. An increase in memory load led to more errors, to longer reaction times and to lower saccadic precision. However, the effect was similar across the three patient groups and the controls. An error analysis indicated that both patients and controls tended to weight global (luminance contrast and form) features higher than local features (line-segment orientation) when making difficult perceptual decisions

    Arthropod communities in fungal fruitbodies are weakly structured by climate and biogeography across European beech forests

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    Aim The tinder fungus Fomes fomentarius is a pivotal wood decomposer in European beech Fagus sylvatica forests. The fungus, however, has regionally declined due to centuries of logging. To unravel biogeographical drivers of arthropod communities associated with this fungus, we investigated how space, climate and habitat amount structure alpha and beta diversity of arthropod communities in fruitbodies of F. fomentarius. Location Temperate zone of Europe. Taxon Arthropods. Methods We reared arthropods from fruitbodies sampled from 61 sites throughout the range of European beech and identified 13 orders taxonomically or by metabarcoding. We estimated the total number of species occurring in fruitbodies of F. fomentarius in European beech forests using the Chao2 estimator and determined the relative importance of space, climate and habitat amount by hierarchical partitioning for alpha diversity and generalized dissimilarity models for beta diversity. A subset of fungi samples was sequenced for identification of the fungus’ genetic structure. Results The total number of arthropod species occurring in fruitbodies of F. fomentarius across European beech forests was estimated to be 600. Alpha diversity increased with increasing fruitbody biomass; it decreased with increasing longitude, temperature and latitude. Beta diversity was mainly composed by turnover. Patterns of beta diversity were only weakly linked to space and the overall explanatory power was low. We could distinguish two genotypes of F. fomentarius, which showed no spatial structuring. Main conclusion Fomes fomentarius hosts a large number of arthropods in European beech forests. The low biogeographical and climatic structure of the communities suggests that fruitbodies represent a habitat that offers similar conditions across large gradients of climate and space, but are characterized by high local variability in community composition and colonized by species with high dispersal ability. For European beech forests, retention of trees with F. fomentarius and promoting its recolonization where it had declined seems a promising conservation strategy

    Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development.

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    Auxin phytohormones control most aspects of plant development through a complex and interconnected signaling network. In the presence of auxin, AUXIN/INDOLE-3-ACETIC ACID (AUX/IAA) transcriptional repressors are targeted for degradation by the SKP1-CULLIN1-F-BOX (SCF) ubiquitin-protein ligases containing TRANSPORT INHIBITOR RESISTANT 1/AUXIN SIGNALING F-BOX (TIR1/AFB). CULLIN1-neddylation is required for SCFTIR1/AFB functionality, as exemplified by mutants deficient in the NEDD8-activating enzyme subunit AUXIN-RESISTANT 1 (AXR1). Here, we report a chemical biology screen that identifies small molecules requiring AXR1 to modulate plant development. We selected four molecules of interest, RubNeddin 1 to 4 (RN1 to -4), among which RN3 and RN4 trigger selective auxin responses at transcriptional, biochemical, and morphological levels. This selective activity is explained by their ability to consistently promote the interaction between TIR1 and a specific subset of AUX/IAA proteins, stimulating the degradation of particular AUX/IAA combinations. Finally, we performed a genetic screen using RN4, the RN with the greatest potential for dissecting auxin perception, which revealed that the chromatin remodeling ATPase BRAHMA is implicated in auxin-mediated apical hook development. These results demonstrate the power of selective auxin agonists to dissect auxin perception for plant developmental functions, as well as offering opportunities to discover new molecular players involved in auxin responses

    Effect of spinal manipulation on sensorimotor functions in back pain patients: study protocol for a randomised controlled trial

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    <p>Abstract</p> <p>Background</p> <p>Low back pain (LBP) is a recognized public health problem, impacting up to 80% of US adults at some point in their lives. Patients with LBP are utilizing integrative health care such as spinal manipulation (SM). SM is the therapeutic application of a load to specific body tissues or structures and can be divided into two broad categories: SM with a high-velocity low-amplitude load, or an impulse "thrust", (HVLA-SM) and SM with a low-velocity variable-amplitude load (LVVA-SM). There is evidence that sensorimotor function in people with LBP is altered. This study evaluates the sensorimotor function in the lumbopelvic region, as measured by postural sway, response to sudden load and repositioning accuracy, following SM to the lumbar and pelvic region when compared to a sham treatment.</p> <p>Methods/Design</p> <p>A total of 219 participants with acute, subacute or chronic low back pain are being recruited from the Quad Cities area located in Iowa and Illinois. They are allocated through a minimization algorithm in a 1:1:1 ratio to receive either 13 HVLA-SM treatments over 6 weeks, 13 LVVA-SM treatments over 6 weeks or 2 weeks of a sham treatment followed by 4 weeks of full spine "doctor's choice" SM. Sensorimotor function tests are performed before and immediately after treatment at baseline, week 2 and week 6. Self-report outcome assessments are also collected. The primary aims of this study are to 1) determine immediate pre to post changes in sensorimotor function as measured by postural sway following delivery of a single HVLA-SM or LVVA-SM treatment when compared to a sham treatment and 2) to determine changes from baseline to 2 weeks (4 treatments) of HVLA-SM or LVVA-SM compared to a sham treatment. Secondary aims include changes in response to sudden loads and lumbar repositioning accuracy at these endpoints, estimating sensorimotor function in the SM groups after 6 weeks of treatment, and exploring if changes in sensorimotor function are associated with changes in self-report outcome assessments.</p> <p>Discussion</p> <p>This study may provide clues to the sensorimotor mechanisms that explain observed functional deficits associated with LBP, as well as the mechanism of action of SM.</p> <p>Trial registration</p> <p>This trial is registered in ClinicalTrials.gov, with the ID number of <a href="http://www.clinicaltrials.gov/ct2/show/NCT00830596">NCT00830596</a>, registered on January 27, 2009. The first participant was allocated on 30 January 2009 and the final participant was allocated on 17 March 2011.</p

    Posture Control—Human-Inspired Approaches for Humanoid Robot Benchmarking: Conceptualizing Tests, Protocols and Analyses

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    Posture control is indispensable for both humans and humanoid robots, which becomes especially evident when performing sensorimotor tasks such as moving on compliant terrain or interacting with the environment. Posture control is therefore targeted in recent proposals of robot benchmarking in order to advance their development. This Methods article suggests corresponding robot tests of standing balance, drawing inspirations from the human sensorimotor system and presenting examples from robot experiments. To account for a considerable technical and algorithmic diversity among robots, we focus in our tests on basic posture control mechanisms, which provide humans with an impressive postural versatility and robustness. Specifically, we focus on the mechanically challenging balancing of the whole body above the feet in the sagittal plane around the ankle joints in concert with the upper body balancing around the hip joints. The suggested tests target three key issues of human balancing, which appear equally relevant for humanoid bipeds: (1) four basic physical disturbances (support surface (SS) tilt and translation, field and contact forces) may affect the balancing in any given degree of freedom (DoF). Targeting these disturbances allows us to abstract from the manifold of possible behavioral tasks. (2) Posture control interacts in a conflict-free way with the control of voluntary movements for undisturbed movement execution, both with “reactive” balancing of external disturbances and “proactive” balancing of self-produced disturbances from the voluntary movements. Our proposals therefore target both types of disturbances and their superposition. (3) Relevant for both versatility and robustness of the control, linkages between the posture control mechanisms across DoFs provide their functional cooperation and coordination at will and on functional demands. The suggested tests therefore include ankle-hip coordination. Suggested benchmarking criteria build on the evoked sway magnitude, normalized to robot weight and Center of mass (COM) height, in relation to reference ranges that remain to be established. The references may include human likeness features. The proposed benchmarking concept may in principle also be applied to wearable robots, where a human user may command movements, but may not be aware of the additionally required postural control, which then needs to be implemented into the robot

    A challenge: Support of standing balance in assistive robotic devices

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    Neurological patients using a powered lower-body exoskeleton for rehabilitation of standing and walking skills in an upright body pose face the safety challenge of postural instability and fall. Current research, therefore, develops exoskeletons with self-balancing functions. This study suggests basing the exoskeleton’s stabilization of standing posture on a human-derived postural control mechanism. A corresponding control system has previously been successfully tested with specific balancing tasks in humanoid robots. Here, we provide a short introduction into the control method and, using a lightweight robot, present as a test of the balancing an experimental shift in the body weight distribution (as if, e.g., a human exoskeleton user was raising an arm or leaning the upper body or lifting an external weight). An overview of other specific balancing tests previously already investigated in humans and humanoids is also briefly mentioned. Overall, the tests will allow the quantification of the capabilities of self-balancing exoskeletons developed for patients with partial paralysis of lower body sensorimotor functions.TU Berlin, Open-Access-Mittel – 202
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