Застосування сервісно-орієнтованих архітектур у процесах інтеграції інформаційних ресурсів

Розглянуто окремі аспекти застосування сервісно-орієнтованої архітектури для рішення завдань горизонтальної інтеграції автономних інформаційних ресурсів.Рассмотрены отдельные аспекты использования сервисно-ориентированной архитектуры для решения задач горизонтальной интеграции автономных информационных ресурсов.Some issues of service-oriented architecture application for solving the task of autonomous information resources horizontal integration are considered

Effects of experience and opponents on pacing behavior and 2-km cycling performance of novice youths

Purpose: To study the pacing behavior and performance of novice youth exercisers in a controlled laboratory setting. Method: Ten healthy participants (seven male, three female, 15.8 ± 1.0 years) completed four, 2-km trials on a Velotron cycling ergometer. Visit 1 was a familiarization trial. Visits 2 to 4 involved the following conditions, in randomized order: no opponent (NO), a virtual opponent (starting slow and finishing fast) (OP-SLOWFAST), and a virtual opponent (starting fast and finishing slow) (OP-FASTSLOW). Repeated measurement ANOVAs (p < .05) were used to examine differences in both pacing behavior and also performance related to power output, finishing- and split times, and RPE between the four successive visits and the three conditions. Expected performance outcome was measured using a questionnaire. Results: Power output increased (F3,27 = 5.651, p = .004, η2p = .386) and finishing time decreased (F3,27 = 9.972, p .05). Conclusion: Performance was improved by an increase in experience after one visit, parallel with the ability to anticipate future workload

Optimal Development of Youth Athletes Toward Elite Athletic Performance: How to Coach Their Motivation, Plan Exercise Training, and Pace the Race

Elite athletes have invested many years in training and competition to reach the elite level. One very important factor on the road to elite performance is the decision-making process regarding the regulation of effort over time, termed as pacing behavior. The regulation of effort is vital for optimal athletic performance during a single race and over a longer period of time (e.g., a competitive season) as an inadequate regulation could result in a higher risk of injuries, overtraining, and drop-out. Despite this, there is limited knowledge on how young athletes learn and develop the abilities related to pacing. Pacing behavior of athletes develops from childhood throughout adolescence and is thought to be closely connected to physical maturation, the development of pre-frontal cortical related (meta-) cognitive functions, as well as the gathering of experience with exercise tasks. The motivation of an athlete can critically influence how an athlete paces a single race, but also how they distribute their effort over a longer period of time. Coaches are advised to closely monitor the development of pacing behavior during adolescence (e.g., by gathering split times, and related physiological measurement, during training and competition), as well as the underlying factors including physical maturation (meta-) cognitive development and the motivation of young athletes. Furthermore, pacing behavior development could be aided by providing training in which the task, individual, and environment are manipulated. Hereby, presenting athletes with the opportunity to gain experience in situations which closely resemble the perceptual-motor conditions of upcoming competitions

Drafting in long-track speed skating team pursuit on the ice rink

Drafting is distinctive for team pursuit races in long-track speed skating. This study aims to compare the impact of drafting on physical intensity (heart rate [HR]) and perceived intensity (ratings of perceived exertion [RPE]) per drafting position. Eighteen skilled male (n = 9) and female (n = 9) skaters (20.0 ± 4.8 years) skated three trials, in first, second or third position, with consistent average velocity (F2,10 = 2.30, p = 0.15, ηp2 = 0.32). Differences in HR and RPE (Borg CR−10 scale) were compared within-subjects (three positions) using a repeated-measures ANOVA (p &lt; 0.05). Compared to the first position, HR was lower in the second (benefit 3.2%) and third (benefit 4.7%) position and lower in third compared to second position (benefit 1.5%), observed in 10 skaters (F2,28 = 28.9, p &lt; 0.001, ηp2= 0.67). RPE was lower when comparing second (benefit 18.5%) and third (benefit 16.8%) position to first (F1.3,22.1 = 7.02, p &lt; 0.05, ηp2= 0.29) and similar for third and second positions., observed in 8 skaters. Even though the physical intensity was lower when drafting in third versus second position, the perceived intensity was equal. There were large interindividual differences between skaters. Coaches are advised to adopt a multidimensional, tailored approach when selecting and training skaters for a team pursuit.</p

Internally Controlled, Generic Real-Time PCR for Quantification and Multiplex Real-Time PCR with Serotype-Specific Probes for Serotyping of Dengue Virus Infections

Dengue has become a global public health problem and a sensitive diagnostic test for early phase detection can be life saving. An internally controlled, generic real-time PCR was developed and validated by testing serial dilutions of a DENV positive control RNA in the presence of a fixed amount of IC with results showing a good linearity (R2 = 0.9967) and a LOD of at least 1.95 × 104 copies/mL. Application of the generic PCR on 136 patient samples revealed a sensitivity of 95.8% and specificity of 100%. A newly developed multiplex real-time PCR with serotype-specific probes allowed the serotyping of DENV for 80 out of 92 (87%) generic real-time PCR positive patients. Combined these real-time PCRs offer a convenient diagnostic tool for the sensitive and specific quantification of DENV in clinical specimens with the possibility for serotyping

Geoteelt : met PrecisieLandbouw naar beter waterbeheer

Een uitleg volgt betreffende het project GEOteelt, dat concrete precisielandbouw toepassingen op het gebied van beregening, bemesting en gewasbescherming beoogt te ontwikkelen en te demonstreren. Het project maakt onderdeel uit van het koepelproject Interactief Waterbeheer (Interreg), dat tal van projecten bevat op het gebied van duurzaam waterbeheer (kwalitatief en kwantitatief). Met 8 kernbedrijven in de grensregio Vlaanderen Nederland (6 bedrijven uit Noord Brabant en 2 bedrijven uit België) richt het project zich op bedrijven in de sectoren akkerbouw en vollegrondsgroenten, en worden combinaties van teelten en precisie toepassingen uitgewerkt, die in 2010 en 2011 zijn beoordeeld op het effect voor waterkwaliteit en waterverbruik. In een voorstudie heeft het projectteam toepassingen geselecteerd, die perspectief bieden

The structure of emotion regulation strategies in adolescence: Differential links to internalizing and externalizing problems

Emotion regulation is a multi-modal construct, that includes both adaptive and maladaptive cognitive-behavioral processes. However, many classifications of regulation strategies do not take this multi-modality into account. In this study, two classification systems were integrated. Participants were 336 adolescents (56% boys, Mage = 15.41, SD = 1.45). Anger regulation strategies were measured with a questionnaire that assessed general strategies, and a vignette measure that assessed contextual strategies. Confirmatory factor analyses supported a 4-factor classification that consisted of cognitive maladaptive, behavioral maladaptive, cognitive adaptive, and behavioral adaptive strategies. The four categories of regulation strategies were differentially associated with age, and gender and psychological problem differences were found. Adolescents wit

High Throughput Method to Quantify Anterior-Posterior Polarity of T-Cells and Epithelial Cells

The virologic synapse (VS), which is formed between a virus-infected and uninfected cell, plays a central role in the transmission of certain viruses, such as HIV and HTLV-1. During VS formation, HTLV-1-infected T-cells polarize cellular and viral proteins toward the uninfected T-cell. This polarization resembles anterior-posterior cell polarity induced by immunological synapse (IS) formation, which is more extensively characterized than VS formation and occurs when a T-cell interacts with an antigen-presenting cell. One measure of cell polarity induced by both IS or VS formation is the repositioning of the microtubule organizing center (MTOC) relative to the contact point with the interacting cell. Here we describe an automated, high throughput system to score repositioning of the MTOC and thereby cell polarity establishment. The method rapidly and accurately calculates the angle between the MTOC and the IS for thousands of cells. We also show that the system can be adapted to score anterior-posterior polarity establishment of epithelial cells. This general approach represents a significant advancement over manual cell polarity scoring, which is subject to experimenter bias and requires more time and effort to evaluate large numbers of cells