314 research outputs found

    Machinelike or Humanlike? A Literature Review of Anthropomorphism in AI-Enabled Technology

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    Due to the recent proliferation of AI-enabled technology (AIET), the concept of anthropomorphism, human likeness in technology, has increasingly attracted researchers’ attention. Researchers have examined how anthropomorphism influences users’ perception, adoption, and continued use of AIET. However, researchers have yet to agree on how to conceptualize and operationalize anthropomorphism in AIET, which has resulted in inconsistent findings. A comprehensive understanding is thus needed of the current state of research on anthropomorphism in AIET contexts. To conduct an in-depth analysis of the literature on anthropomorphism, we reviewed 35 empirical studies focusing on conceptualizing and operationalizing AIET anthropomorphism, and its antecedents and consequences. Based on our analysis, we discuss potential research gaps and offer directions for future research

    Selecting and Testing of Cement-Bonded Magnetite and Chalcopyrite as Oxygen Carrier for Chemical-Looping Combustion

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    Combining iron and copper ores can generate an oxygen carrier that has a synergic effect of high temperature resistance and high reactivity. In this work, typical cements available in the market were studied as binders to bind magnetite and chalcopyrite to develop a suitable oxygen carrier for chemical-looping combustion (CLC). A first selection step suggested that an aluminate cement, namely CA70, could favor the generation of oxygen carrier particles having good crushing strength, good particle yield, and high reactivity. The CA70-bonded oxygen carrier was then subjected to cyclic tests with CH4, CO, and H-2 in reduction and in air oxidation at temperatures of 850, 900, and 950 degrees C with gas concentrations of 5, 10, 15, and 20% in a batch-fluidized bed reactor. The increase in temperature promoted the fuel conversion. At 950 degrees C, the conversions of CH4 and CO reached up to 80.4% and 99.2%, respectively. During more than 30 cycles, the oxygen carrier kept a similar reactivity to the fresh carrier and maintained its composition and physical properties. The oxygen transport capacity was maintained at 21-23%, and the phases were CuO, Fe2O3, Al2O3, and minor CaS. In the used sample, some grains were observed, but the morphology was not greatly changed. Agglomeration was absent during all the cycles, except for the deep reduction with H-2

    Effects of gap size, gap age, and bamboo Fargesia denudata on Abies faxoniana recruitment in South-western China

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    Aim of study: to study the effects of gap size, gap age and bamboo Fargesia denudata on natural regeneration of Abies faxoniana, both of which are the ubiquitous dominants in our research area.Area of study: subalpine coniferous forests in Wanglang Natural Reserve in Southwestern China.Material and Methods: 10 transect belts were randomly established, and a total of 97 gaps were recorded and used.Main results: (1) the number of bamboos with coverage of <17% significantly increased with increases of gap size and age, but the latter had little influence on the numbers of F. denudata with coverage of >17%. (2) F. denudata strongly inhibited A. faxoniana seedlings and saplings in small, young and old gaps, where the amount of A. faxoniana recruitment was relatively abundant, than in other types of gap. (3) The numbers of A. faxoniana seedlings in A-gaps, significantly decreased with the increases in gap size. However, in gaps where F. denudate was also present, A. faxoniana seedlings and saplings were insensitive to gap size or age. Research highlights: thick F. denudata would not be influenced by gap size or age. Because of the low occurrences of A. faxoniana seedlings and saplings, the negative effect of gap size, gap age and F. denudata on A. faxoniana recruitment was unclear.Key words: Abies faxoniana; Fargesia denudata; gap age; gap size; regeneration

    Pregabalin alleviates postherpetic neuralgia by downregulating spinal TRPV1 channel protein

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    Purpose: To determine the mechanism involved in pregabalin-induced alleviation of postherpetic neuralgia in a rat model.Methods: Ninety-sixty healthy Sprague-Dawley (SD) rats were assigned to sham, model andpregabalin groups (32 rats per group). A model of postherpetic neuralgia (PN) was established. The expressions of IL-1ÎČ and TNF-α in spinal cord tissue were determined 7 days after administration of treatments. The proportions of fluorescence areas in astrocytes in the dorsal horn, prefrontal lobe and hippocampus, and level of spinal cord TRPV1 channel protein in each group were evaluated.Results: Relative to model rats, IL-1ÎČ and TNF-α in spinal cord of pregabalin rats were significantly reduced (p < 0.05). The areas of fluorescence in astrocytes in dorsal horn of spinal cord, prefrontal lobe and hippocampus of model group were significantly increased, relative to sham, but were decreased in rats in pregabalin group (p < 0.05).Conclusion: Pregabalin significantly alleviates postherpetic neuralgia via mechanisms which may be related to the inflammatory response of spinal dorsal horn and downregulation of TRPV1 channel protein expression. This finding may be useful in developing new drugs for alleviating postherpetic neuralgia

    StaPep: an open-source tool for the structure prediction and feature extraction of hydrocarbon-stapled peptides

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    Many tools exist for extracting structural and physiochemical descriptors from linear peptides to predict their properties, but similar tools for hydrocarbon-stapled peptides are lacking.Here, we present StaPep, a Python-based toolkit designed for generating 2D/3D structures and calculating 21 distinct features for hydrocarbon-stapled peptides.The current version supports hydrocarbon-stapled peptides containing 2 non-standard amino acids (norleucine and 2-aminoisobutyric acid) and 6 nonnatural anchoring residues (S3, S5, S8, R3, R5 and R8).Then we established a hand-curated dataset of 201 hydrocarbon-stapled peptides and 384 linear peptides with sequence information and experimental membrane permeability, to showcase StaPep's application in artificial intelligence projects.A machine learning-based predictor utilizing above calculated features was developed with AUC of 0.85, for identifying cell-penetrating hydrocarbon-stapled peptides.StaPep's pipeline spans data retrieval, cleaning, structure generation, molecular feature calculation, and machine learning model construction for hydrocarbon-stapled peptides.The source codes and dataset are freely available on Github: https://github.com/dahuilangda/stapep_package.Comment: 26 pages, 6 figure

    Attenuation by a Human Body and Trees as well as Material Penetration Loss in 26 and 39 GHz Millimeter Wave Bands

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    This paper investigates the attenuation by a human body and trees as well as material penetration loss at 26 and 39 GHz by measurements and theoretical modeling work. The measurements were carried out at a large restaurant and a university campus by using a time domain channel sounder. Meanwhile, the knife-edge (KE) model and one-cylinder and two-cylinder models based on uniform theory of diffraction (UTD) are applied to model the shape of a human body and predict its attenuation in theory. The ITU (International Telecommunication Union) and its modified models are used to predict the attenuation by trees. The results show that the upper bound of the KE model is better to predict the attenuation by a human body compared with UTD one-cylinder and two-cylinder models at both 26 and 39 GHz. ITU model overestimates the attenuation by willow trees, and a modified attenuation model by trees is proposed based on our measurements at 26 GHz. Penetration loss for materials such as wood and glass with different types and thicknesses is measured as well. The measurement and modeling results in this paper are significant and necessary for simulation and planning of fifth-generation (5G) mm-wave radio systems in ITU recommended frequency bands at 26 and 39 GHz

    Nomogram based on computed tomography images and clinical data for distinguishing between primary intestinal lymphoma and Crohn’s disease: a retrospective multicenter study

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    BackgroundDifferential diagnosis of primary intestinal lymphoma (PIL) and Crohn’s disease (CD) is a challenge in clinical diagnosis.AimsTo investigate the validity of the nomogram based on clinical and computed tomography (CT) features to identify PIL and CD.MethodsThis study retrospectively analyzed laboratory parameters, demographic characteristics, clinical manifestations, and CT imaging features of PIL and CD patients from two centers. Univariate logistic analysis was performed for each variable, and laboratory parameter model, clinical model and imaging features model were developed separately. Finally, a nomogram was established. All models were evaluated using the area under the curve (AUC), accuracy, sensitivity, specificity, and decision curve analysis (DCA).ResultsThis study collected data from 121 patients (PIL = 69, CD = 52) from Center 1. Data from 43 patients (PIL = 24, CD = 19) were collected at Center 2 as an external validation cohort to validate the robustness of the model. Three models and a nomogram were developed to distinguish PIL from CD. Most models performed well from the external validation cohort. The nomogram showed the best performance with an AUC of 0.921 (95% CI: 0.838–1.000) and sensitivities, specificities, and accuracies of 0.945, 0.792, and 0.860, respectively.ConclusionA nomogram combining clinical data and imaging features was constructed, which can effectively distinguish PIL from CD
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