Educating Greek Students about Climate Change through Serious Games

In Greece, climate change is projected to have detrimental effects, disrupting agricultural production, wildlife species, public health and economic standing. Studies have shown that increasing education can help combat climate change. The goal of this project was to develop serious games about climate change as resources for the Environmental Education Centre of Eleftherio-Kordelio and educators throughout Greece. Using a knowledge survey, observations, and other forms of assessment, we developed, tested, and refined 6 serious games with 185 students. These games, along with 8 others, are presented in a booklet that can be disseminated to Greek educators

Content Validity of the Quality of Life Scale for Patients with Work-related Musculoskeletal Disorders (QoL-WMSD Scale)

This work is the second part of an in progress research which is supported by the Brazilian Network for Health Technology Assessment (REBRATS) whose the main objective is to develop, validate, and standardize the Quality of Life Scale for Patients with Work-related Musculoskeletal Disorders (QoL-WMSD) to the Brazilian context. Methods. We interviewed fourteen patients participating in a support group constituted by individuals with WMSD. Patients were asked to say what quality of life means to them. From these responses, we found the descriptors and dimensions linked to the quality of life construct. The findings of the content analysis were gathered with a systematic literature review by searching a wide range of medical and psychological journals. Descriptors and dimensions pertaining to other quality of life measures were also investigated with the goal of finding specific and general characteristics that could contribute to developing the QoL-WMSD Scale. Findings. The set of 72 descriptors was organized into 4 dimensions: 1) Physical Aspects, which include the sub dimensions Mobility and Locomotion, Pain and Discomfort, and Independence; 2) Occupational Aspects, that involve the sub dimensions Chance of Disability, Financial Difficulties, and Stability and Security; 3) Psychological Aspects; and 4) Social Aspects, which include the sub dimensions Leisure and Social Support. An additional sub-scale was developed to evaluate general aspects of quality of life that were potentially affected by the specific WMSD. Conclusions. From these dimensions, the items will be investigated in a five-point Likert scale distributed in two sub-scales. The first sub-scale will explore the intensity of some aspects of quality of life before acquiring a work-related musculoskeletal disorder, and the second sub-scale will ask for these aspects during the WMSD. Dimensions, descriptors and items of the QoL-WMSD Scale will be presented as a result of the content validity process

Decreased levels of alpha-1-acid glycoprotein are related to the mortality of septic patients in the emergency department

OBJECTIVE: To determine the validity of alpha-1-acid glycoprotein as a novel biomarker for mortality in patients with severe sepsis. METHODS: We prospectively included patients with severe sepsis or septic shock at the emergency department at a single tertiary referral teaching hospital. All of the patients were enrolled within the first 24 hours of emergency department admission, and clinical data and blood samples were obtained. As the primary outcome, we investigated the association of serum levels of alpha-1-acid glycoprotein and 96-hour mortality with logistic regression analysis and generalized estimating equations adjusted for age, sex, shock status and Acute Physiology and Chronic Health Evaluation II score. RESULTS: Patients with septic shock had lower alpha-1-acid glycoprotein levels at the time of emergency department admission compared to patients without shock (respectively, 149.1 ±42.7 vs. 189.8 ±68.6; p = 0.005). Similarly, non-survivors in the first 96 hours were also characterized by lower levels of alpha-1-acid glycoprotein at the time of emergency department admission compared to survivors (respectively, 132.18 ±50.2 vs. 179.8 ±61.4; p = 0.01). In an adjusted analysis, alpha-1-acid glycoprotein levels ≤120 mg/dL were significantly associated with 96-hour mortality (odds ratio = 14.37; 95% confidence interval = 1.58 to 130.21). CONCLUSION: Septic shock patients exhibited lower circulating alpha-1-acid glycoprotein levels than patients without shock. Alpha-1-acid glycoprotein levels were independently associated with 96-hour mortality in individuals with severe sepsis

Estimativa de consumo de búfalos e bovinos em regime de pastoreio rotativo racional

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Pharmacogenetics of glucocorticoid replacement could optimize the treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency

INTRODUCTION: 21-hydroxylase deficiency is an autosomal recessive disorder that causes glucocorticoid deficiency and increased androgen production. Treatment is based on glucocorticoid replacement; however, interindividual variability in the glucocorticoid dose required to achieve adequate hormonal control has been observed. OBJECTIVE: The present study aimed to evaluate the association between polymorphic variants involved inglucocorticoid action and/or metabolism and the mean daily glucocorticoid dose in 21-hydroxylase deficiency patients. METHODS: We evaluated 53 patients with classical forms of 21-hydroxylase deficiency who were receiving cortisone acetate. All patients were between four and six years of age and had normal androgen levels. RESULTS: The P450 oxidoreductase A503V, HSD11B1 rs12086634, and CYP3A7*1C variants were found in 19%, 11.3% and 3.8% of the patients, respectively. The mean ± SD glucocorticoid dose in patients with the CYP3A7*1C and wild-type alleles was 13.9 ± 0.8 and 19.5 ± 3.2 mg/m²/d, respectively. We did not identify an association between the P450 oxidoreductase or HSD11B1 allelic variants and the mean glucocorticoid dose. CONCLUSION: Patients carrying the CYP3A7*1C variant required a significantly lower mean glucocorticoid dose. Indeed, the CYP3A7*1C allele accounted for 20% of the variability in the cortisone acetate dose. The analysis of genes involved in glucocorticoid metabolism may be useful in the optimization of treatment of 21-hydroxylase deficiency

Avaliação de jurubeba juna (Solanum stramonifolium Jacq) como porta-enxerto para tomateiro em Altamira-PA.

O objetivo deste ensaio foi o de avaliar a jurubeba juna como porta-enxerto para tomateiro, em Altamira-PA.bitstream/item/201326/1/BPD-187.pd

Resposta de cultivares de berinjela à murcha bacteriana em Altamira, PA.

O objetivo deste ensaio foi o de avaliar a resposta de cinco cultivares comerciais de berinjela à infestação de Ralstonia pseudosolanacearum, nas condições ambientais de Altamira, PA, em ambiente altamente favorável à ocorrência da murcha bacteriana.bitstream/item/201327/1/BPD-184.pd

Identification of eight solanum (subgenus Leptostemonum) species as novel natural hosts of tomato chlorosis virus in Brazil.

Made available in DSpace on 2018-10-20T00:41:01Z (GMT). No. of bitstreams: 1 apsjournals.apsnet.orgIdentificationofEightSolanumsubgenusLeptostemonumSpeciesasNovelNaturalHostsofTomatochlor.pdf: 185191 bytes, checksum: 75d5ae8b373c6ee00c3f263aea39dc02 (MD5) Previous issue date: 2018-10-19bitstream/item/184757/1/apsjournals.apsnet.org-Identification-of-Eight-Solanum-subgenus-Leptostemonum-Species-as-Novel-Natural-Hosts-of-Tomato-chlor.pd

First report on the whitefly, Aleurodicus pseudugesii on the coconut palm, Cocos nucifera in Brazil.

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