1,627 research outputs found

    Diluted antiferromagnet in a ferromagnetic enviroment

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    The question of robustness of a network under random ``attacks'' is treated in the framework of critical phenomena. The persistence of spontaneous magnetization of a ferromagnetic system to the random inclusion of antiferromagnetic interactions is investigated. After examing the static properties of the quenched version (in respect to the random antiferromagnetic interactions) of the model, the persistence of the magnetization is analysed also in the annealed approximation, and the difference in the results are discussed

    A inscrição tumular de Fr. António de Nebrixa

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    A Crónica da Província da Piedade, de Fr. Manuel de Monforte, é um manancial inesgotável de informações de toda a ordem: históricas, literárias, artísticas, arqueológicas, linguísticas. O autor, frade da mesma província, serve-se de um estilo terso e tão nítido, que a exposição nunca resulta emaranhada ou confusa, nem mesmo quando se embrenha pelos caminhos intrincados das fontes documentais para a história da Ordem e das suas primeiras casas de religiosos. Vai o leitor anotando todos esses informes, relacionando conhecimentos, e concluindo como os ensinamentos de uma ciência aproveitam a outra; neste caso concreto, como a história literária aproveita à epigrafia, e vice-versa

    Uma inscrição gótica da Madre de Deus

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    Uma visita ao conjunto arquitectónico da Madre de Deus é sempre útil e instrutiva para quem se interesse pela Arte, nas suas mais variadas manifestações: arquitectura, escultura, pintura, ourivesaria, azulejaria, e até epigrafia

    Exemplos de numeração indefinida ou indeterminada em lápides da Lusitânia

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    Naturalmente o autor estranhou que, num conjunto de 15 monumentos, sabendo de antemão que eram raros os casos de longevidade naqueles tempos, aparecessem 2 com a indicação precisa da idade de 100 anos; mais ainda: numa mesma lápide duas pessoas com a mesma idade de 100 anos. Tal estranheza levou o Dr. Inês Vaz, e a meu ver com razão, a formular esta dúvida: «...não será uma forma de indicar uma idade avançada?

    Efeito da aplicação de doses de boro via foliar na cultura do melão.

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    Objetivando avaliar o efeito da aplicação via foliar de doses de Boro na cultura do melão foi desenvolvido o presente trabalho em condições de campo. Foram aplicadas 7 doses de Boro através de ácido bórico. O experimento foi desenvolvido em delineamento blocos ao acaso com 3 repetições. Após finalização do experimento, pode-se constatar que das variáveis analisadas apenas a produtividade para o mercado externo (ME), a produtividade comercial (PC), a produtividade total (PT) e o BRIX, responderam à aplicação de doses de B. Para todas as variáveis, o aumento da dose de B proporcionou uma diminuição da produtividade. Apenas o BRIX dos frutos aumentou com o aumento da dose de B.1 CD-ROM

    Efeito de doses de zinco na produtividade e composição mineral do melão.

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    O presente trabalho teve por objetivo avaliar o efeito da aplicação via foliar de 8 doses de Zinco na cultura do melão. O experimento foi desenvolvido em delineamento blocos ao acaso com 3 repetições. Após finalização do experimento, pode-se constatar que das variáveis analisadas apenas a produtividade para o mercado externo (ME), a produtividade comercial (PC) e a produtividade total (PT), responderam à aplicação de doses de Zn. Para todas as variáveis, o aumento da dose de Zn acarretou uma diminuição da produtividade. Com relação à acumulação de Zn nas plantas, observou-se que com o aumento da dose de Zn houve uma maior acumulção deste elemento na planta

    Gla-rich protein (GRP) as an early and novel marker of vascular calcification and kidney dysfunction in diabetic patients with CKD: a pilot cross-sectional study

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    Vascular calcification (VC) is one of the strongest predictors of cardiovascular risk in chronic kidney disease (CKD) patients. New diagnostic/prognostic tools are required for early detection of VC allowing interventional strategies. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor, whose clinical utility is here highlighted. The present study explores, for the first time, correlations between levels of GRP in serum with CKD developmental stage, mineral metabolism markers, VC and pulse pressure (PP), in a cohort of 80 diabetic patients with mild to moderate CKD (stages 2-4). Spearman's correlation analysis revealed a positive association of GRP serum levels with estimated glomerular filtration rate (eGFR) and α-Klotho, while a negative correlation with phosphate (P), fibroblast growth factor 23 (FGF-23), vascular calcification score (VCS), PP, calcium (x) phosphate (CaxP) and interleukin 6 (IL-6). Serum GRP levels were found to progressively decrease from stage 2 to stage 4 CKD. Multivariate analysis identified low levels of eGFR and GRP, and high levels of FGF-23 associated with both the VCS and PP. These results indicate an association between GRP, renal dysfunction and CKD-mineral and bone disorder. The relationship between low levels of GRP and vascular calcifications suggests a future, potential utility for GRP as an early marker of vascular damage in CKD.Portuguese Society of Nephrology (SPN) ; Portuguese national funds from FCT-Foundation for Science and Technology through the transitional provision DL57/2016/CP1361/CT0006 UIDB/04326/2020info:eu-repo/semantics/publishedVersio

    Um Caso Clínico de Lepra Multibacilar com Vários Surtos de Eritema Nodoso Leproso

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    Leprosy is a chronic granulomatous disease with a long incubation period caused by Mycobacterium leprae that mainly affects the skin, mucous membranes and the peripheral nervous system. It carries the risk of per-manent sequels with a significant impact on the patient’s quality of life. It has a considerable clinically diver-sity and possible atypical presentations. We present a case of a 31-year-old, skin phototype V woman with multibacillary leprosy characterized by multiple outbreaks of erythema nodosum leprosum, as an inaugural manifestation of the disease. The disease was acquired within a group of children and adolescents from an endemic region of Africa, evolved untreated for 3 years, and presented with unusual features and remarkable lymphatic involvement. We highlight the importance of building and maintaining collaboration between expert centers and institutional partnerships in order to provide the adequate diagnostic resources and appropriate care to the affected populations.A lepra é uma doença granulomatosa crónica com longo período de incubação causada pelo bacilo Mycobacte- -rium leprae que afeta principalmente a pele, mucosas e sistema nervoso periférico. Tem risco de sequelas permanentes e impacto significativo na qualidade de vida do paciente. É clinicamente heterogénea com possíveis apresentações atípicas. Descrevemos o caso de uma mulher de 31 anos, fototipo V, com lepra multibacilar caracterizada por múltiplos surtos de eritema nodoso leproso como manifestação inaugural. A doença foi adquirida num grupo de crianças e adolescentes de uma região endémica de África, evoluiu sem tratamento durante 3 anos, e manifestou-se com algumas características clínicas incomuns e notável envolvimento linfático. Destacamos a importância da colaboração entre centros especializados e parcerias institucionais, a fim de fornecer os recursos de diagnósti-co e os cuidados adequados às populações afetadas

    Anxiety and depression symptoms after pulmonary rehabilitation in people with interstitial lung disease: responders and non-responders

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    Pulmonary rehabilitation (PR) is an effective intervention for people with interstitial lung disease (ILD), as it improvesexercise capacity, quality of life and dyspnoea. Less is, however, known about other important and frequentsymptoms, such as anxiety and depression. This study explored the response of anxiety and depression symptomsto PR in people with ILD. Participants undertook a 12-week community-based PR programme. Anxiety and depression symptoms wereevaluated before and after PR with the hospital anxiety and depression scale (HADS). The sample was stratified into2 groups according to the HADS score: ≥8 probable anxiety (PA) or depression (PD) and score <8 normal symptoms(NS). Responders were classified using the HADS minimal clinical important difference (≥1.5 points). 46 people with ILD (62±13 years; 63%♀; 75±20 FVC%; 56±18 DLCO%) participated. Number of responders inanxiety symptoms (73% PA; HADS-A pre: 12±3; mean change: 4±2; p<0.001 vs 25% NS; HADS-A pre: 6±2; meanchange: 2±0; p<0.001) was much higher than in depression symptoms (27% PD; HADS-D pre: 11±3; mean change:3±1; p=0.014 vs 13% NS; HADS-D pre: 5±2; mean change: 2±1; p=0.003). PR seems to improve anxiety symptoms, but it might not be as effective for depression symptoms in people with ILD.Future studies are needed to investigate the role of PR in the psychological health of people with ILD.publishe

    Embedding Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease in the Home and Community Setting: A Rapid Review

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    This paper presents a rapid review of the literature for the components, benefits, barriers, and facilitators of pulmonary rehabilitation for chronic obstructive pulmonary disease (COPD) people in-home and community-based settings. seventy-six studies were included: 57 home-based pulmonary rehabilitation (HBPR) studies and 19 community-based pulmonary rehabilitation (CBPR) studies. The benefits of HBPR on exercise capacity and health-related quality of life were observed in one-group studies, studies comparing HBPR to usual care, and studies comparing to hospital-based pulmonary rehabilitation, although the benefits were less pronounced in the latter. HBPR reduced hospital admissions compared to usual care and was more cost-effective than hospital pulmonary rehabilitation. Most HBPRs were designed with low-density or customized equipment, are minimally supervised, and have a low intensity of training. Although the HBPR has flexibility and no travel burden, participants with severe disease, physical frailty, and complex comorbidities had barriers to complying with HBPR. The telerehabilitation program, a facilitator for HBPR, is feasible and safe. CBPR was offered in-person supervision, despite being limited to physical therapists in most studies. Benefits in exercise capacity were shown in almost all studies, but the improvement in health-related quality of life was controversial. Patients reported the benefits that facilities where they attended the CBPR including social support and the presence of an instructor. They also reported barriers, such as poor physical condition, transport difficulties, and family commitments. Despite the minimal infrastructure offered, HBPR and CBPR are feasible, safe, and provide clinical benefits to patients with COPD. Home and community settings are excellent opportunities to expand the offer of pulmonary rehabilitation programs, as long as they follow protocols that ensure quality and safety following current guidelines
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