Inclusion of transverse shear deformation in the exact buckling and vibration analysis of composite plate assemblies

The problem considered is the development of the necessary plate stiffnesses for use in the general purpose program VICONOPT for buckling and vibration of composite plate assemblies. The required stiffnesses include the effects of transverse shear deformation and are for sinusoidal response along the plate length as required in VICONOPT. The method is based on the exact solution of the plate differential equations for a composite laminate having fully populated A, B, and D stiffness matrices which leads to an ordinary differential equation of tenth order

The method of improving intonation for violinests and violists students in faculty of music UiTM Shah Alam / Melvin David

The method of improving intonation for violinists and violists students in Faculty of Music, UiTM Shah Alam is a study to find the causes of intonation problem and to find the methods to improve intonation in violin and viola playing. The study was conducted at the Faculty of Music, UiTM Shah Alam, among the undergraduate students in the faculty. The data of the study was collected through the distribution of questionnaires with the use of qualitative method

Spin-polarized low energy electron diffraction studies of Cu¿Au(001)

Combined measurements in low-energy electron diffraction of both intensity and diffracted electron spin-polarization are obtained for Cu,Au(1). Here the use of polarized LEED represents a refinement over standard LEED techniques because additional and complementary data is obtained. In addition, the recent implementation of a spin-modulated polarized electron source allows the rapid and simultaneous acquisition of PLEED I-V and P-V spectra. The order-disorder transition at the Cu,Au(1) surface, near the bulk transition temperature (at Tc=391°C), seems only slightly to affect PLEED profiles. The polarization of the (1) beam has been studied as a function of temperature between room temperature and 44°C. Although significant polarizations were noted, no dramatic transition-dependent polarization changes were found. Temperature dependent changes in the profiles are noted, and may be attributed to standard thermal scattering according to the Debye-Waller factor. In addition, angular studies of the specular diffraction were obtained, and may be used to characterize the ordered state at room temperature

Gα16, a G Protein α Subunit Specifically Expressed in Hematopoietic Cells

Signal-transduction pathways mediated by guanine nucleotide-binding regulatory proteins (G proteins) determine many of the responses of hematopoietic cells. A recently identified gene encoding a G protein α subunit, Gα16, is specifically expressed in human cells of the hematopoietic lineage. The Gα16 cDNA encodes a protein with predicted Mr of 43,500, which resembles the Gq class of α subunits and does not include a pertussis toxin ADP-ribosylation site. In comparison with other G protein α subunits, the Gα16 predicted protein has distinctive amino acid sequences in the amino terminus, the region A guanine nucleotide-binding domain, and in the carboxyl-terminal third of the protein. Cell lines of myelomonocytic and T-cell phenotype express the Gα16 gene, but no expression is detectable in two B-cell lines or in nonhematopoietic cell lines. Gα16 gene expression is down-regulated in HL-60 cells induced to differentiate to neutrophils with dimethyl sulfoxide. Antisera generated from synthetic peptides that correspond to two regions of Gα16 specifically react with a protein of 42- to 43-kDa in bacterial strains that overexpress Gα16 and in HL-60 membranes. This protein is decreased in membranes from dimethyl sulfoxide-differentiated HL-60 cells and is not detectable in COS cell membranes. The restricted expression of this gene suggests that Gα16 regulates cell-type-specific signal-transduction pathways, which are not inhibited by pertussis toxin

Patterns in International Warfare, 1816-1965

Patterns in international violence are discovered through the quantitative analysis of international wars which resulted in more than 1,000 battle-connected deaths. Between 1816 and 1965, members of the state system participated in 50 such interstate wars and 43 such colonial and imperial conflicts. Although no secular trends are evident in terms of the fre quency, magnitude, severity, and intensity of these wars, the data suggest a twenty-year cycle in the magnitude of systemic war. Over two thirds of all of the wars began in either the spring or the autumn. Major powers have engaged in a dis proportionate number of wars and have suffered the most bat tle-connected deaths. These same powers, however, have won most of their wars. Those on the victorious side have often been the initiators of military hostilities. Enduring military friendships and enmities have been uncommon over the 150- year period. Further use of these basic war data should be helpful in the assault upon the centuries-old problem of the causes of war.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68229/2/10.1177_000271627039100112.pd

A Comparative Study on the Optical Properties of Multilayer CdSe / CdTe Thin Film with Single Layer CdTe and CdSe Films

CdTe and CdSe single layer thin films and CdSe / CdTe multilayer (ML) thin film were prepared by using physical vapour deposition method. Optical properties of CdSe / CdTe multilayer thin film shows different behavior due to type II band structure alignment. Energy band gap value of CdSe / CdTe ML thin film is shifted to higher value than that of single layer CdTe film. This is due to decrease in crystallite size to dimension smaller than the Bohr exciton radius of CdTe (14 nm). Crystallite size of the multilayer sample was calculated with the predictions of the effective mass approximation model (i.e., Brus model). It is observed that the photoluminescence peak of CdSe / CdTe ML thin film is red shifted compared to the peaks corresponding to individual CdSe and CdTe thin films. This may be due to the presence of type II quantum dot formation in the CdSe / CdTe heterostructure multilayer thin film. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3193

Recent developments in Lipodystrophy

Purpose of review: Lipodystrophy syndromes have an estimated prevalence of 1.3–4.7 cases per million and as with other rare diseases conducting research can be challenging. The purpose of this review is to highlight recently published work that has provided important insights into the field of non-HIV associated lipodystrophy syndromes. Recent findings: Lipodystrophies are a heterogenous group of disorders and as such research is often focused on specific subtypes of the condition. The identification of children affected by LMNA mutations provided insights into the natural history of FPLD2, specifically that the adipose tissue phenotype predates the onset of puberty. Recent reports of heterozygous null variant carriers and the apparent absence of a lipodystrophy phenotype challenges our understanding of the molecular biology of perilipin 1 and its role in the pathogenesis of FPLD4. With a focus on therapeutics, studies delineating the differential responsiveness of PPAR gamma mutants to endogenous and synthetic ligands illustrated the potential for pharmacogenetics to inform therapeutic decisions in lipodystrophy due to PPARG mutations, while robust human studies have contributed important insights into the food independent metabolic effects of leptin in lipodystrophy. Finally, rare syndromes of lipodystrophy continue to serve as an exemplar for the contribution of genetically determined adipose tissue expandability to metabolic disease in the general population. Keywords: Lipodystrophy; LMNA; PLIN1; PPARG; Leptin