566 research outputs found

    The Impact of Judicial Decisions: New Dimensions in Supreme Court-Congressional Relations, 1945-1968

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    This research report is an investigation of Congressional roll call behavior and interest group activity in response to Supreme Court decisions involving civil rights and liberties, and economic, labor and welfare issues. The report is designed to explore the nature and relative stability of those variables which may influence Congressmen when they vote on judiciary-oriented roll calls in the above mentioned issue categories

    401: Stem cell transplantation for osteopetrosis One center’s experience

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    A physically based approach for the estimation of root-zone soil moisture from surface measurements

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    Abstract. In the present work, we developed a new formulation for the estimation of the soil moisture in the root zone based on the measured value of soil moisture at the surface. It was derived from a simplified soil water balance equation for semiarid environments that provides a closed form of the relationship between the root zone and the surface soil moisture with a limited number of physically consistent parameters. The method sheds lights on the mentioned relationship with possible applications in the use of satellite remote sensing retrievals of soil moisture. The proposed approach was used on soil moisture measurements taken from the African Monsoon Multidisciplinary Analysis (AMMA) and the Soil Climate Analysis Network (SCAN) databases. The AMMA network was designed with the aim to monitor three so-called mesoscale sites (super sites) located in Benin, Mali, and Niger using point measurements at different locations. Thereafter the new formulation was tested on three additional stations of SCAN in the state of New Mexico (US). Both databases are ideal for the application of such method, because they provide a good description of the soil moisture dynamics at the surface and the root zone using probes installed at different depths. The model was first applied with parameters assigned based on the physical characteristics of several sites. These results highlighted the potential of the methodology, providing a good description of the root-zone soil moisture. In the second part of the paper, the model performances were compared with those of the well-known exponential filter. Results show that this new approach provides good performances after calibration with a set of parameters consistent with the physical characteristics of the investigated areas. The limited number of parameters and their physical interpretation makes the procedure appealing for further applications to other regions

    Application of a model-based rainfall-runoff database as efficient tool for flood risk management

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    A framework for a comprehensive synthetic rainfall-runoff database was developed to study catchment response to a variety of rainfall events. The framework supports effective flood risk assessment and management and implements simple approaches. It consists of three flexible components, a rainfall generator, a continuous rainfallrunoff model, and a database management system. The system was developed and tested at two gauged river sections along the upper Tiber River (central Italy). One of the main questions was to investigate how simple such approaches can be applied without impairing the quality of the results. The rainfall-runoff model was used to simulate runoff on the basis of a large number of rainfall events. The resulting rainfallrunoff database stores pre-simulated events classified on the basis of the rainfall amount, initial wetness conditions and initial discharge. The real-time operational forecasts follow an analogue method that does not need new model simulations. However, the forecasts are based on the simulation results available in the rainfall-runoff database (for the specific class to which the forecast belongs). Therefore, the database can be used as an effective tool to assess possible streamflow scenarios assuming different rainfall volumes for the following days. The application to the study site shows that magnitudes of real flood events were appropriately captured by the database. Further work should be dedicated to introduce a component for taking account of the actual temporal distribution of rainfall events into the stochastic rainfall generator and to the use of different rainfall-runoff models to enhance the usability of the proposed procedure

    TEMPO-oxidized cellulose nanofibril/polyvalent cations hydrogels: a multifaceted view of network interactions and inner structure

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    In the last years, hydrogels from renewable biopolymers and low-cost row materials are a hot topic for biomedical applications. In this context, cellulose nanofibrils are considered suitable building blocks for the synthesis of many biocompatible products, with a variety of chemical-physical properties. Herein we report a multi-technique and multi-scale study, from the molecular to the nanometric length scale, of the sol-gel transition observed in aqueous solutions of TEMPO-oxidized nano-sized cellulose fibrils (TOCNFs), when in the presence of polyvalent cations (Mg2+ and Ca2+). We combine the data from Small Angle Neutron Scattering (SANS), which provide information about the inner structure of the nanofibril, with those from UV Resonant Raman (UVRR) spectroscopy, which is a sensitive probe of the intra- and inter-molecular interactions in the gel and the liquid state. The transition between the gel and the liquid phases is investigated as a function of the concentration of both TOCNFs and cations, the nature of the latter, and the pH at which the phenomenon is observed. SANS analysis reveals that ion concentration induces an anisotropic swelling in the nanofibrils which, at the same time, become more and more flexible. The nanofibrils flexibility is also dependent on TOCNF concentration and pH value. UVRR allows us to elucidate the structural organization and hydrogen-bonding properties of water in aqueous TOCNF dispersions and gels, showing how water molecules partially lose their typical bulk-like tetrahedral organization when ions are added, and the gel phase is formed

    Toward the estimation of river discharge variations using MODIS data in ungauged basins

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    This study investigates the capability of the Moderate resolution Imaging Spectroradiometer (MODIS) to estimate river discharge, even for ungauged sites. Because of its frequent revisits (as little as every 3 h) and adequate spatial resolution (250 m), MODIS bands 1 and 2 have significant potential for mapping the extent of flooded areas and estimating river discharge even for medium-sized basins. Specifically, the different behaviour of water and land in the Near Infrared (NIR) portion of the electromagnetic spectrum is exploited by computing the ratio (C/M) of the MODIS channel 2 reflectance values between two pixels located within (M) and outside (C), but close to, the river. The values of C/M increase with the presence of water and, hence, with discharge. Moreover, in order to reduce the noise effects due to atmospheric contribution, an exponential smoothing filter is applied, thus obtaining C/M⁎. Time series of hourly mean flow velocity and discharge between 2005 and 2011 measured at four gauging stations located along the Po river (Northern Italy) are employed for testing the capability of C/M⁎ to estimate discharge/flow velocity. Specifically, the meanders and urban areas are considered the best locations for the position of the pixels M and C, respectively. Considering the optimal pixels, the agreement between C/M⁎ and discharge/flow velocity is fairly good with values in the range of 0.65–0.77. Additionally, the application to ungauged sites is tested by deriving a unique regional relationship between C/M⁎ and flow velocity valid for the whole Po river and providing only a slight deterioration of the performance. Finally, the sensitivity of the results to the selection of the C and M pixels is investigated by randomly changing their location. Also in this case, the agreement with in situ observations of velocity is fairly satisfactory (r ~ 0.6). The obtained results demonstrate the capability of MODIS to monitor discharge (and flow velocity). Therefore, its application for a larger number of sites worldwide will be the object of future studies

    First study on the peptidergic innervation of the brain superior sagittal sinus in humans.

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    The superior sagittal sinus (SSS) of the mammalian brain is a pain-sensitive intracranial vessel thought to play a role in the pathogenesis of migraine headaches. Here, we aimed to investigate the presence and the potential co-localization of some neurotransmitters in the human SSS. Immunohistochemical and double-labeling immunofluorescence analyses were applied to paraformaldehyde-fixed, paraffin-embedded, coronal sections of the SSS. Protein extraction and Western blotting technique were performed on the same material to confirm the morphological data. Our results showed nerve fibers clustered mainly in large bundles tracking parallel to the longitudinal axis of the sinus, close in proximity to the vascular endothelium. Smaller fascicles of fibers encircled the vascular lumen in a spiral fashion, extending through the subendothelial connective tissue. Isolated nerve fibers were observed around the openings of bridging veins in the sinus or around small vessels extending into the perisinusal dura. The neurotransmitters calcitonin gene related peptide (CGRP), substance P (SP), neuronal nitric oxide synthase (nNOS), vasoactive intestinal polypeptide (VIP), tyrosine hydroxylase (TH), and neuropeptide Y (NPY) were found in parietal nerve structures, distributed all along the length of the SSS. Overall, CGRP- and TH-containing nerve fibers were the most abundant. Neurotransmitters co-localized in the same fibers in the following pairs: CGRP/SP, CGRP/NOS, CGRP/VIP, and TH/NPY. Western blotting analysis confirmed the presence of such neurosubstances in the SSS wall. Overall our data provide the first evidence of the presence and co-localization of critical neurotransmitters in the SSS of the human brain, thus contributing to a better understanding of the sinus functional role
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