Serological profile of foot-and-mouth disease in wildlife populations of West and Central Africa with special reference to Syncerus caffer subspecies

The role which West and Central African wildlife populations might play in the transmission dynamics of FMD is not known nor have studies been performed in order to assess the distribution and prevalence of FMD in wild animal species inhabiting those specific regions of Africa. This study reports the FMD serological profile extracted from samples (n = 696) collected from wildlife of West and Central Africa between 1999 and 2003. An overall prevalence of FMDV NSP reactive sera of 31.0% (216/696) was estimated, where a significant difference in seropositivity (p = 0.000) was reported for buffalo (64.8%) as opposed to other wild animal species tested (17.8%). Different levels of exposure to the FMDV resulted for each of the buffalo subspecies sampled (p = 0.031): 68.4%, 50.0% and 0% for Nile Buffalo, West African Buffalo and African Forest Buffalo, respectively. The characterisation of the FMDV serotypes tested for buffalo found presence of antibodies against all the six FMDV serotypes tested, although high estimates for type O and SAT 3 were reported for Central Africa. Different patterns of reaction to the six FMDV serotypes tested were recorded, from sera only positive for a single serotype to multiple reactivities. The results confirmed that FMDV circulates in wild ruminants populating both West and Central Africa rangelands and in particular in buffalo, also suggesting that multiple FMDV serotypes might be involved with type O, SAT 2 and SAT 1 being dominant. Differences in serotype and spill-over risk between wildlife and livestock likely reflect regional geography, historical circulation and differing trade and livestock systems

Pan-African Genetic Structure in the African Buffalo (Syncerus caffer): Investigating Intraspecific Divergence

The African buffalo (Syncerus caffer) exhibits extreme morphological variability, which has led to controversies about the validity and taxonomic status of the various recognized subspecies. The present study aims to clarify these by inferring the pan-African spatial distribution of genetic diversity, using a comprehensive set of mitochondrial D-loop sequences from across the entire range of the species. All analyses converged on the existence of two distinct lineages, corresponding to a group encompassing West and Central African populations and a group encompassing East and Southern African populations. The former is currently assigned to two to three subspecies (S. c. nanus, S. c. brachyceros, S. c. aequinoctialis) and the latter to a separate subspecies (S. c. caffer). Forty-two per cent of the total amount of genetic diversity is explained by the between-lineage component, with one to seventeen female migrants per generation inferred as consistent with the isolation-with-migration model. The two lineages diverged between 145 000 to 449 000 years ago, with strong indications for a population expansion in both lineages, as revealed by coalescent-based analyses, summary statistics and a star-like topology of the haplotype network for the S. c. caffer lineage. A Bayesian analysis identified the most probable historical migration routes, with the Cape buffalo undertaking successive colonization events from Eastern toward Southern Africa. Furthermore, our analyses indicate that, in the West-Central African lineage, the forest ecophenotype may be a derived form of the savanna ecophenotype and not vice versa, as has previously been proposed. The African buffalo most likely expanded and diverged in the late to middle Pleistocene from an ancestral population located around the current-day Central African Republic, adapting morphologically to colonize new habitats, hence developing the variety of ecophenotypes observed today

Bears in human-modified landscapes: The case studies of the Cantabrian, Apennine, and Pindos Mountains

Brown bears Ursus arctos were historically persecuted and almost eradicated from Southern Europe in the 20th century as a result of hunting and direct persecution (Zedrosser et al. 2011; Martínez Cano et al. 2016). The effects of human induced mortality were exacerbated by other threats, such as habitat loss and fragmentation, due to the expansion of human populations (Swenson et al. 2000). As a result, nowadays there are only small fragmented populations of bears in Southern Europe, where brown bears frequently inhabit human modified landscapes. These areas are characterised by the widespread presence of people and infrastructures, which potentially have ecological impacts on bears. The close coexistence of brown bears and humans generates multiple human-driven disturbances (Ordiz et al. 2017) and causes bear mortality (Bischof et al. 2009), affecting the distribution, demography, behaviour and viability of bear populations (Penteriani et al. 2018a; Zarzo-Arias et al. 2018). Brown bears in the Cantabrian (north-western Spain), Apennine (central Italy) and Pindos (north-western Greece) mountains (Figure 19.1) represent three examples of small and threatened bear populations in human-modified landscapes (Figure 19.2). Most of their range is characterised by high human densities, widespread agricultural activities, livestock raising and urban development, connected by dense networks of transport infrastructures (Penteriani et al. submitted; Mateo-Sánchez et al. 2016). This has resulted in a reduction of continuous habitat suitable for the species (Martínez Cano et al. 2016). Here, we summarise the past and present histories and fates of these three populations as examples on how the coexistence of bears and people in human-modified landscapes can take different turns depending on human attitudes

Brown Bear (Ursus arctos; Eurasia)

The brown bear and cave bear (Ursus spelaeus) diverged in Eurasia approximately 1.2-1.4 million years ago (Loreille et al. 2001) and brown bears subsequently inhabited most of the continent. Here we review how climatic fluctuations during and after the Pleistocene shaped the genetic relationships within Eurasian brown bears, especially focusing on the effects of the Last Glacial Maximum (LGM, 26-19,000 years ago), when most of northern Eurasia was covered with continental ice sheets (Saarma et al. 2007)