590 research outputs found
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Honour based violence and the multi-agency approach in Nottingham: response of local agencies to honour based violence
The focus of the research was to gain an understanding of the current levels of HBV in Nottingham and the nature of the multi-agency response. The main aim of the research was to gain an understanding of practitioners' work with a range of issues relating to honour based violence (HBV)within partnership agencies. The revised Violence Against Women and Girls Strategy Action Plan published by the government in2010 (Home Office, 2010) gave precedence to a co-ordinated approach to ending all forms of violence against women including HBV and forced marriage
Is There Life after \u3cem\u3eBryan\u3c/em\u3e?: The Validity of Rule 10b-5\u27s Misappropriation Theory
Reltionship between variation the TP53 gene and patient outcomes following severe traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of death and disability with millions of people living with long-term complications or disability related to TBI in the United States alone. This study examined the relationship between the p53 coding gene (TP53) and outcome variability following severe TBI. p53 has a known impact on neuronal apoptosis following TBI, which warrants investigation into TP53 genetic variability as a prognosticator for TBI outcomes (assessed using the Glasgow Outcome Scale, Neurobehavioral Scale, and Disability Rating Scale.) Participants (n = 429) were recruited from the UPMC Presbyterian Hospital with a Glasgow Coma Score £8 and were followed for 24 months. The single nucleotide polymorphism (SNP) rs1042522 was analyzed using restriction fragment length polymorphism (RFLP) and digested with BstuI restriction enzyme. Individuals with the CC genotype (Arginine homozygotes) were at risk for poorer outcomes following TBI at the 24-month point when compared to CG/GG variants. The findings provide preliminary evidence that p53 plays a role in recovery following TBI and, if replicated, may warrant investigation into p53 targeted therapies for risk allele carriers
Deaf immigrants in the northeast United States: intelligibility & the interpersonal
How does being an immigrant shape the experience of being deaf in the United States and vice versa?Drawing from approximately 18 months of ethnographic fieldwork in the northeast United States, this research examines the lived experiences of deaf immigrants with a particular attention to their communicative encounters and languaging practices. This article focuses on the collaborative nature of deaf immigrants’ languaging to argue that understanding in communicative encounters is co-produced and that intelligibility is achieved relationally. Through ethnographic examples, I emphasize the importance of interpersonal relationships to establishing understanding in deaf immigrant communicative interactions and argue that, in encounters with the United States immigration regime, the social and interpersonal dimensions of communication are at least as significant (if not more so) than the linguistic dimensions to achieving such understanding
Cochlear implants and codas: the impact of a technology on a community
There has been a great amount of debate between the medical community and the Deaf community regarding cochlear implants. Indeed, some factions of the Deaf community have reacted with hostility to the development of the technology and have protested its implementation. Existing literature examines Deaf individuals' perceptions of cochlear implants, however there has been a significant lack of academic attention paid to the hearing children of deaf adults (codas). As children of deaf parents, codas grow up simultaneously inhabiting two worlds: the Deaf world of their parents and the hearing world of their peers. It is codas' unique position and loyalties between the Deaf world and the hearing world that make them important to the cochlear implant debate. This study investigates codas' perceptions of cochlear implantation using standard ethnographic methods, including in-depth, open-ended interviewing with codas, and immersion in the research population through ongoing participant-observation at a deaf school. The findings suggest that (1) codas' interstitial identity impacts their perceptions of and attitudes towards cochlear implantation and (2) cochlear implants have contributed to a refinement of Coda identity in relation to the Deaf community
Section 2 of the Voting Rights Act of 1965 - Non-Voting Purge Statute
The United States Court of Appeals for the Third Circuit held that Pennsylvania\u27s non-voting purge statute did not deny minorities equal access to the political process.
Oritz v. City of Philadelphia, 28 F.3d 306 (3d Cir. 1994)
Relationship between variation in the TP53 gene and patient outcomes following severe traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of death and disability with millions of people living with long-term complications or disability related to TBI in the United States alone. This study examined the relationship between the p53 coding gene (TP53) and outcome variability following severe TBI. p53 has a known impact on neuronal apoptosis following TBI, which warrants investigation into TP53 genetic variability as a prognosticator for TBI outcomes (assessed using the Glasgow Outcome Scale, Neurobehavioral Scale, and Disability Rating Scale.) Participants (n = 429) were recruited from the UPMC Presbyterian Hospital with a Glasgow Coma Score 8 and were followed for 24 months. The single nucleotide polymorphism (SNP) rs1042522 was analyzed using restriction fragment length polymorphism (RFLP) and digested with BstuI restriction enzyme. Individuals with the CC genotype (Arginine homozygotes) were at risk for poorer outcomes following TBI at the 24-month point when compared to CG/GG variants. The findings provide preliminary evidence that p53 plays a role in recovery following TBI and, if replicated, may warrant investigation into p53 targeted therapies for risk allele carriers
Geology of the seabed and shallow subsurface: the Irish Sea
The British Geological Survey was commissioned by the Crown Estate to assess geological conditions in the Irish Sea in relation to the possible constraints they may place on development of offshore infrastructure. The report describes the geology between 0 m and 50 m below seabed, which is the depth most relevant to current pile foundation technology.
The report reviews the best available data from a variety of sources including, BGS legacy data, map sheets, and regional reports, as well as site investigations carried out for hydrocarbon and offshore renewable industries. Additional data collected for the proposed Round 3 offshore wind farm in the Irish Sea (Celtic Array) was also included. Prof. Richard Chiverrell and Dr. Katrien Van Landeghem (of Liverpool and Bangor universities), who together have extensive experience working in the Irish Sea, provided valuable advice and guidance.
The report is split into four principle sections as summarised below.
Section 3 summarises seabed topography, sediments and processes. The topography of the report area is split into shallow platforms and deeper troughs. Seabed sediments are subdivided into regions of soft mud- (clay and silt) rich sediment in the eastern and western Irish Sea and a central gravel belt comprising coarse sand and gravel. Small areas of bedrock outcrop at seabed are also recognised. Currents in the Irish Sea mobilise sediment to form a collection of marine bedforms ranging from ripples to very large (up to 36 m in height) solitary sediment waves and banner banks. Predicting bedform migration speeds and pathways is difficult and requires repeat surveys. Bedform migration rates of 0 m/yr to 66 m/yr, with average values around 6 m/yr have been observed. Shallow gas is expected in some areas of the Irish Sea. Where this gas is present, pockmarks or methane derived authigenic carbonate may occur.
Section 4 summarises the Quaternary history of the Irish Sea and its impact on the distribution, thickness and properties of sediment. Growth and collapse of ice sheets and associated sea level fluctuations principally determine geological properties of Quaternary sediments. The stratigraphy in the report area reflects three major glacial periods with the last one having the most pronounced influence. Very stiff diamicts (glacial ‘boulder clays’ or tills) are present across most of the report area of variable thickness. In enclosed deeps, locally sediment thickness can be >100 m. Glacial landforms are preserved at the seabed and can be used to predict sediment properties. Extensive studies onshore can provide analogues to assess potential geological properties offshore.
Section 5 provides a review of bedrock distribution and properties. Where Quaternary sediment cover is <50 m, bedrock will be encountered in the shallow subsurface. The predominant bedrock lithologies in the report area are Triassic and Carboniferous sandstone and mudstone. Geotechnical properties of Triassic rocks are comparable and potentially predictable. Carboniferous rock show high lateral and vertical variability. There are a number of igneous intrusions in the report area and rock properties near to the location of these igneous bodies may differ due to alteration of the host rock during intrusion.
Section 6 summarises the geological constraints identified in preceding sections with reference to engineering activities and infrastructure.
The report outlines the current state of knowledge of geological conditions in the Irish Sea. It is recommended for use as a guide and should not replace a detailed site investigation
Space Shuttle Familiarization
This slide presentation visualizes the NASA space center and research facility sites, as well as the geography, launching sites, launching pads, rocket launching, pre-flight activities, and space shuttle ground operations located at NASA Kennedy Space Center. Additionally, highlights the international involvement behind the International Space Station and the space station mobile servicing system. Extraterrestrial landings, surface habitats and habitation systems, outposts, extravehicular activity, and spacecraft rendezvous with the Earth return vehicle are also covered
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