Circulating miRNA Profiling in Plasma Samples of Ovarian Cancer Patients

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A large-scale assessment of hand hygiene quality and the effectiveness of the “WHO 6-steps”

BACKGROUND: Hand hygiene compliance is generally assessed by observation of adherence to the “WHO five moments” using numbers of opportunities as the denominator. The quality of the activity is usually not monitored since there is no established methodology for the routine assessment of hand hygiene technique. The aim of this study was to objectively assess hand rub coverage of staff using a novel imaging technology and to look for patterns and trends in missed areas after the use of WHO’s 6 Step technique. METHODS: A hand hygiene education and assessment program targeted 5200 clinical staff over 7 days at the National University Hospital, Singapore. Participants in small groups were guided by professional trainers through 5 educational stations, which included technique-training and UV light assessment supported by digital photography of hands. Objective criteria for satisfactory hand hygiene quality were defined a priori. The database of images created during the assessment program was analyzed subsequently. Patterns of poor hand hygiene quality were identified and linked to staff demographic. RESULTS: Despite the assessment taking place immediately after the training, only 72% of staff achieved satisfactory coverage. Failure to adequately clean the dorsal and palmar aspects of the hand occurred in 24% and 18% of the instances, respectively. Fingertips were missed by 3.5% of subjects. The analysis based on 4642 records showed that nurses performed best (77% pass), and women performed better than men (75% vs. 62%, p<0.001). Further risk indicators have been identified regarding age and occupation. CONCLUSION: Ongoing education and training has a vital role in improving hand hygiene compliance and technique of clinical staff. Identification of typical sites of failure can help to develop improved training

Új low back pain prevenciós mozgásprogram, amely javítja a törzsizmok állapotát és a lumbalis motoros kontrollt | Improvement of lumbal motor control and trunkmuscle conditions with a novel low back pain prevention exercise program

Absztrakt: Bevezetés: A balett-táncosok gyakran szenvednek deréktáji fájdalomtól. Célkitűzés: Speciális mozgásprogrammal, a törzsizmok erősítése révén, a deréktáji fájdalmak csökkentése. Módszer: 62 balett-táncosnőt (átlagéletkor: 14,89 ± 1,21 év) vizsgáltunk. Kezelt csoport: n = 30 fő, átlagéletkor: 14,86 ± 1,00 év, kontrollcsoport: n = 32 fő, átlagéletkor: 14,91 ± 1,37 év. Vizuális analóg skálával vizsgáltuk az edzéseken jelentkező derékfájdalom intenzitását, fotogrammetriás vizsgálattal habituális testtartásukat, Kraus–Weber-teszttel a hasizmok erejét, core-teszttel a törzsizmok statikus erejét, leg lowering teszttel a lumbalis motoros kontroll képességet. A kezelt csoport három hónapig LBP prevenciós mozgásprogramot végzett, majd újból elvégeztük a vizsgálatokat. Eredmények: Szignifikánsan csökkent az esetcsoport derékfájásának intenzitása (VAS1: p = 0,012; VAS2: p = 0,021), szignifikánsan javult hasizomereje (K–W. B: p = 0,025; K–W. C: p<0,001), a törzsizmok statikus ereje (core-test: p<0,001), lumbalis motoros kontroll képessége, mindkét láb esetében (Leg low. J.: p<0,001; Leg low. B.: p<0,001). A habituális testtartás magas százalékban javult (elölnézet: 34,78%, oldalnézet: 52,17%). Következtetés: A speciális mozgásprogrammal csökkenthető a balett-táncosok derékfájdalma, a sérülések előfordulási gyakorisága. Orv. Hetil., 2017, 158(2), 58–66. | Abstract: Introduction: Ballet dancers often suffer from low back pain. Aim: Low back pain can be reduced by strengthening the core muscles with the help of a special exercise program. Materials and methods: In the study 62 ballet dancer women (average age: 14.89 ± 1.21 years) were included. Intervention group: n = 30 participant, average age: 14.86 ± 1.00 years, control group: n = 32 participant, average age: 14.91 ± 1.37 years. We examined the pain intensity that occurs during training with visual analog scale, the habitual posture with photogrammetry, the abdominal muscle strength with Kraus–Weber test, the static muscle strength of the trunk muscles with core test and the lumbar motor control with leg lowering test. The intervention group did a trunk prevented exercise program during 3 months, and then we examined them again. Results: In the intervention group the intensity of pain significantly decreased (VAS1: p = 0.012; VAS2: p = 0.021), the abdominal muscle strength significantly improved (K–W. B: p=0.025; K–W. C: p<0.001), the static muscle strength of trunk muscles significantly increased (Core-test: p<0.001) and the lumbar motor control significantly improved in both legs (Leg low. R.: p<0.001; Leg low. L.: p<0.001). Also, the habitual posture greatly improved (frontal view: 34.78%, side view: 52.17%). Conclusion: In ballet dancers with a special exercise program, which improves the conditions of trunk muscles, the motor control of lumbar regions can be improved and the lower back pain and the incidence of injuries can be reduced. Orv., Hetil., 2017, 158(2), 58–66

Circulating epithelial-mesenchymal transition-associated miRNAs are promising biomarkers in ovarian cancer

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BACK SCHOOL PROGRAM: DEVELOPMENT OF BACK CARE KNOWLEDGE AND SPINE DISEASE PREVENTION AND TRUNK STATE AMONG 6-7-YEAR-OLD CHILDREN

Introduction: The prevalence of posture deformities and muscle weakness among primary school children is high (50-65%). Objective: To assess and improve the back care knowledge and spine disease prevention, the strength of the trunk muscles, the flexibility of the lower limb muscles, the posture, and the lumbar motor control ability of primary school children by a 1-school year back school program. Methods: 102 (mean age: 6.549±0.500 years) children were examined at the baseline, and 48 (23 boys, 25 girls) were chosen for the program. Back care knowledge was examined by validated questionnaire, trunk muscle strength, and muscle flexibility by Lehmann tests, posture by New York Posture Rating Chart, and lumbar motor control by Sitting Forward Lean Test. Results: The complete back care knowledge (2.423±3.911, 19.115±2.833 points; p<0.001), trunk flexor (3.615±7.910, 56.885±113.748 sec; p<0.001), trunk extensor (8.962±5.963, 77.000±139.801 sec; p<0.001) static muscle strength, lower limb flexibility (p<0.001), habitual posture (53.846±10.130, 81.154±9.829 points; p<0.001), posture deemed correct 40.962±16.311, 91.346±6.566 points; p<0.001) and lumbar motor control (8.269±5.474, 0.154±0.368 mm; p<0.001) significantly improved in the intervention group for the end of the program. Conclusions: The back school program improves the back care knowledge and the trunk state among 6-7 years old children

A CD24 mRNS-expresszió meghatározása kvantitatív valósidejű PCR-módszerrel alacsonyan differenciált szerózus papilláris petefészekrákos szöveti mintákból

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Effect of active and passive techniques used in thromboembolic prophylaxis on venous flow velocity in the post-procedure period

IntroductionStudies have shown that using mechanical thromboembolic prophylaxis methods speeds up venous flow and decreases stasis. These studies examine the post-intervention period of 1–10 min. The length of the effect of procedures to raise venous flow velocity cannot be determined by clinical trials. To apply mathematical techniques to estimate how long mechanical thromboembolism prophylaxis procedures will increase venous flow rate.MethodsIn the survey, we examined 25 persons (poststroke patients), with an average age of 57.2 ± 6.3 years. Regarding the proportion of genders, 13 (52%) participants were male and 12 (48%) female. The peak venous blood flow velocity was measured with a HADECO BIDOP ES-100V II type Doppler ultrasound device, using an 8 MHz head, in the femoral vein, at the level of the hip joint. We estimated the change of the venous blood flow velocity from the available sampled data using the method of least squares. For the calculations, we used Microsoft Excel, version Mac Excel 2019.ResultsThe decrease in peak venous flow velocity can be approximated by a logarithm function. Mathematical calculations show that after active thromboembolic prophylaxis interventions, resting venous flow velocity is restored at 26.8 min on the intact limb and 85.1 min on the hemiparetic side. Resting flow velocity is restored in 131.9 min after passive mobilization of the hemiparetic side and in 137.7 min after the consensual effect.DiscussionAn elementary mathematical function can be used to estimate the time to recovery of peak venous flow velocity to resting state from measurements taken 15 min after the intervention. Active and passive mechanical thromboembolic prophylaxis after the intervention has a longer-term effect on venous flow velocity