Sunti delle lezioni di diritto costituzionale / date dal sig. professore L. A. Melegari nella Università di Torino l'anno scolastico 1858-59; compilati da alcuni studenti per uso de' loro condiscepoli. (Primo volume)

315 p. ; 22 cm

Sunti delle lezioni di diritto costituzionale date nella Universitá di Torino l'anno scolastico 1856-57 / dal sig. professore L. A. Melegari ; compilati da alcuni studenti per uso dei loro condiscepoli

CLXXXVI, 248 p. ; 22 cm Pubbl. manoscritta Sul front.: Anno 1. di corso

Sunti delle lezioni di diritto costituzionale / date dal sig. professore L. A. Melegari nella Università di Torino l'anno scolastico 1857-58: compilati da alcuni studenti per uso de' loro condiscepoli. (secondo volume)

359 p. ; 22 cm

Híbridos e variedades de milho submetidos à inoculação de sementes com Herbaspirillum seropedicae.

Resumo: A fixação biológica de nitrogênio proporcionada por bactérias diazotróficas pode representar alternativa para a produção de milho em sistemas agrícolas mais sustentáveis ou de baixa utilização de insumos. Objetivando-se avaliar o crescimento, teor e acúmulo de nitrogênio em genótipos de milho, em função da inoculação das sementes com Herbaspirillum seropedicae, foi conduzido experimento em casa de vegetação avaliando-se 35 genótipos de milho híbridos simples, duplo, triplo e variedades. Para inoculação das sementes foi utilizado inoculante turfoso contendo a estirpe bacteriana de H. seropedicae (ZAE 94). Entre os genótipos comerciais de milho estudados, apenas nove híbridos apresentam ganhos de crescimento ou acúmulo de N com a inoculação das sementes com a estirpe Herbaspirillum seropedicae (ZAE 94). Há distinção de resposta entre cultivares de milho em termos de produção de biomassa e incremento de teor de N na parte aérea das plantas. Abstract: The biological nitrogen fixation provided by diazotrophic bacteria may represent an alternative to maize production in more sustainable agricultural systems or low use of technology. In order to evaluate the growth, content and accumulation of nitrogen in corn genotypes, depending on seed inoculation with Herbaspirillum seropedicae experiment was conducted in greenhouse evaluating 35 corn genotypes hybrid single, double, triple and varieties. For seed inoculation was used peat inoculant containing the bacterial strain of H. seropedicae (ZAE 94). Among the commercial corn genotypes studied, only nine hybrids show increase of growth or accumulation of N with the seed inoculation with Herbaspirillum seropedicae (ZAE 94). There is a distinction in response between maize cultivars in terms of biomass production and increase of N content in the shoots

Impressive long-term response with chemo-endocrine therapy in a premenopausal patient with metastatic breast cancer: A case report

RATIONALE: Patients with, or who develop, metastatic breast cancer have a 5-year relative survival of about 25%. Endocrine therapy clearly improves outcomes in patients with estrogen receptor-positive breast cancer. In the metastatic setting, the primary goal of treatment is to maintain long-term disease control with good quality of life. Rarely, exceptional responders achieve durable disease control, and potential cures cannot be ruled out. PATIENT CONCERNS: We report the case of a 39-year-old woman with primary breast cancer and associated synchronous bone metastases, who experienced a disease response of 12 years with hormonal therapy as maintenance after first line chemotherapy, with a good toxicity profile. DIAGNOSIS: The patient was diagnosed with estrogen receptor + human epidermal growth factor receptor 2 (HER2)- metastatic breast cancer with synchronous bone metastases. INTERVENTIONS: This patient was treated with chemotherapy for 6 cycles as a first-line therapy following by endocrine treatment given as a maintenance therapy. OUTCOMES: Our patient experienced a progression-free survival >12 years with an exceptionally good quality of life. LESSONS: Our anecdotal experience highlights the existence of exceptional responders among patients with hormone receptor-positive metastatic breast cancer, who achieve clinical remission and durable disease control with endocrine therapy. Being able to identify these patients could help in the selection of the best treatment option among the many available

Molecular Survey on Kobuviruses in Domestic and Wild Ungulates From Northwestern Italian Alps

Since the first identification in 1989 in humans, kobuviruses (KoVs) have been identified from a wide range of animal species including carnivores, rodents, birds, ungulates, rabbits, and bats. Several studies have described the identification of genetically related KoVs in the fecal virome of domestic and wild animals suggesting a mutual exchange of viruses. By screening a total of 231 fecal samples from wild and domestic ungulates, KoVs RNA was detected in wild boars (3.2%; 2/63), chamois (4.6%; 2/43), and goats (2.6%; 2/77). On phylogenetic analysis of the partial RdRp sequence, the wild boar strains clustered within the species Aichivirus C whilst the strains identified in domestic and wild ruminants grouped into the species Aichivirus B. The complete VP1 gene was obtained for chamois and goat KoVs. Interestingly, upon phylogenetic analysis the strains grouped together with a KoV of ovine origin within a distinct genetic type (B3) of the species Aichivirus B

Molecular detection of canine bufaviruses in wild canids

Novel protoparvoviruses genetically related to human and non-human primate bufaviruses (BuVs) have been detected recently in respiratory and enteric specimens collected from dogs and cats. In this study, by molecular screening of archival collections of faecal samples from wolves and foxes, we detected BuVs with a rate of 17.1% (7/41) and 10.5% (9/86), respectively. Sequence analysis of a portion of the ORF2 gene region of nine positive samples showed that the viruses in these samples were closely related to BuVs (97.5–99.0% nucleotide sequence identity) found in domestic carnivores

Is psychiatric residential facility discharge possible and predictable? A multivariate analytical approach applied to a prospective study in Italy

A growing number of severely ill patients require long-term care in non-hospital residential facilities (RFs). Despite the magnitude of this development, longitudinal studies surveying fairly large resident samples and yielding important information on this population have been very few

Innate immunity changes in soccer players after whole-body cryotherapy

Whole-body cryotherapy (WBC) consists of short exposure (up to 2–3 min) to dry air at cryogenic temperatures (up to -190 °C) and has recently been applied for muscle recovery after injury to reduce the inflammation process. We aimed to determine the impact of cryotherapy on immunological, hormonal, and metabolic responses in non-professional soccer players (NPSPs). Nine male NPSPs (age: 20 ± 2 years) who trained regularly over 5 consecutive days, immediately before and after each training session, were subjected to WBC treatment (WBC-t). Blood samples were collected for the evaluation of fifty analytes including hematologic parameters, serum chemistry, and hormone profiles. Monocytes phenotyping (Mo) was performed and plasmatic markers, usually increased during inflammation [CCL2, IL-18, free mitochondrial (mt)DNA] or with anti-inflammatory effects (IL2RA, IL1RN), were quantified. After WBC-t, we observed reduced levels of ferritin, mean corpuscular hemoglobin, mean platelet volume, testosterone, and estradiol, which however remain within the normal ranges. The percentage of the total, intermediates and non-classical Mo increased, while classical Mo decreased. CXCR4 expression decreased in each Mo subset. Plasma IL18 and IL2RA levels decreased, while IL1RN only exhibited a tendency to decrease and CCL2 showed a tendency to increase. Circulating mtDNA levels were not altered following WBC-t. The differences observed in monocyte subsets after WBC-t may be attributable to their redistribution into the surrounding tissue. Moreover, the decrease of CXCR4 in Mo subpopulations could be coherent with their differentiation process. Thus, WBC through yet unknown mechanisms could promote their differentiation having a role in tissue repair