1,105 research outputs found
The MASSIVE Survey - VIII. Stellar Velocity Dispersion Profiles and Environmental Dependence of Early-Type Galaxies
We measure the radial profiles of the stellar velocity dispersions,
, for 90 early-type galaxies (ETGs) in the MASSIVE survey, a
volume-limited integral-field spectroscopic (IFS) galaxy survey targeting all
northern-sky ETGs with absolute -band magnitude mag, or
stellar mass , within 108 Mpc. Our wide-field
107" 107" IFS data cover radii as large as 40 kpc, for which we
quantify separately the inner (2 kpc) and outer (20 kpc) logarithmic slopes
and of . While
is mostly negative, of the 56 galaxies with sufficient
radial coverage to determine we find 36% to have rising
outer dispersion profiles, 30% to be flat within the uncertainties, and 34% to
be falling. The fraction of galaxies with rising outer profiles increases with
and in denser galaxy environment, with 10 of the 11 most massive galaxies
in our sample having flat or rising dispersion profiles. The strongest
environmental correlations are with local density and halo mass, but a weaker
correlation with large-scale density also exists. The average is similar for brightest group galaxies, satellites, and isolated
galaxies in our sample. We find a clear positive correlation between the
gradients of the outer dispersion profile and the gradients of the velocity
kurtosis . Altogether, our kinematic results suggest that the increasing
fraction of rising dispersion profiles in the most massive ETGs are caused (at
least in part) by variations in the total mass profiles rather than in the
velocity anisotropy alone.Comment: Accepted/in press, MNRA
The MASSIVE Survey - VII. The Relationship of Angular Momentum, Stellar Mass and Environment of Early-Type Galaxies
We analyse the environmental properties of 370 local early-type galaxies
(ETGs) in the MASSIVE and ATLAS3D surveys, two complementary volume-limited
integral-field spectroscopic (IFS) galaxy surveys spanning absolute -band
magnitude , or stellar mass . We find these galaxies to reside in a diverse range of
environments measured by four methods: group membership (whether a galaxy is a
brightest group/cluster galaxy, satellite, or isolated), halo mass, large-scale
mass density (measured over a few Mpc), and local mass density (measured within
the th neighbour). The spatially resolved IFS stellar kinematics provide
robust measurements of the spin parameter and enable us to examine
the relationship among , , and galaxy environment. We find a
strong correlation between and , where the average
decreases from to below 0.1 with increasing mass, and the fraction
of slow rotators increases from % to 90%. We show for
the first time that at fixed , there are almost no trends between galaxy
spin and environment; the apparent kinematic morphology-density relation for
ETGs is therefore primarily driven by and is accounted for by the joint
correlations between and spin, and between and environment. A
possible exception is that the increased at high local density
is slightly more than expected based only on these joint correlations. Our
results suggest that the physical processes responsible for building up the
present-day stellar masses of massive galaxies are also very efficient at
reducing their spin, in any environment.Comment: Accepted to MNRA
The Crowdsourced “Classics” and the Revealing Limits of Goodreads Data
This presentation draws from forthcoming work on the Goodreads "classics."
Goodreads is the largest social networking site for readers on the internet (90 million users) and a subsidiary of Amazon. The “classics” are one of the most active Goodreads categories, with some of the most rated and reviewed books across the entire site. Why are the classics so popular on Goodreads? Which books have readers “shelved” as classics most often? What do the classics mean to contemporary readers? We use computational methods such as topic modeling to investigate these questions and more.
We also interrogate the limits of Goodreads data and the influence of Goodreads/Amazon's proprietary algorithms on reviews. We find that reviews sorted by the default algorithm, for example, tend to be longer, more socially conscientious (e.g. include a spoiler alert), and written by a smaller set of Goodreads users. Extrapolating from these findings, we argue that computational methods can provide a way of documenting, understanding, and critiquing algorithmic culture and its effects
The MASSIVE Survey - X. Misalignment between Kinematic and Photometric Axes and Intrinsic Shapes of Massive Early-Type Galaxies
We use spatially resolved two-dimensional stellar velocity maps over a
field of view to investigate the kinematic features of 90
early-type galaxies above stellar mass in the MASSIVE
survey. We measure the misalignment angle between the kinematic and
photometric axes and identify local features such as velocity twists and
kinematically distinct components. We find 46% of the sample to be well aligned
(), 33% misaligned, and 21% without detectable rotation
(non-rotators). Only 24% of the sample are fast rotators, the majority of which
(91%) are aligned, whereas 57% of the slow rotators are misaligned with a
nearly flat distribution of from to . 11
galaxies have and thus exhibit minor-axis ("prolate")
rotation in which the rotation is preferentially around the photometric major
axis. Kinematic misalignments occur more frequently for lower galaxy spin or
denser galaxy environments. Using the observed misalignment and ellipticity
distributions, we infer the intrinsic shape distribution of our sample and find
that MASSIVE slow rotators are consistent with being mildly triaxial, with mean
axis ratios of and . In terms of local kinematic features,
51% of the sample exhibit kinematic twists of larger than , and 2
galaxies have kinematically distinct components. The frequency of misalignment
and the broad distribution of reported here suggest that the most
massive early-type galaxies are mildly triaxial, and that formation processes
resulting in kinematically misaligned slow rotators such as gas-poor mergers
occur frequently in this mass range.Comment: Accepted to MNRA
Knowledge Bank and Publishing Partners Meeting 2016
The University Archives has determined that this item is of continuing value to OSU's history.8th Annual Knowledge Bank and Publishing Partners Meetin
A new procedure for the template synthesis of metal nanowires
A new procedure for the fabrication of metal nanowires by template assisted electrodeposition using porous polycarbonate templates is described. A thin sputtered film of silver (≤15 nm) was deposited onto one side of the template. The silver seed layer was used to catalyse electroless copper deposition and a copper layer was grown on top (300 - 500 nm) in less than 10 min. The copper layer served to seal the pores of the template and to form an electrode of high electrical conductivity. The copper layer was easily removed with a chemical etchant to aid the release of the nanowires from the template mask after growth. To demonstrate the process, copper nanowires were prepared by controlled potential deposition and characterised by SEM and TEM. This new procedure has the ability to be applied to the preparation of a wide range of metallic nanostructures over a wide range of scales. It avoids the need for an extended vacuum deposition step and has the advantage of using low cost metals in a combined short vacuum / wet chemical process so as to form the critical electrode layer for nanowire growth
Local Stressors Reduce Coral Resilience to Bleaching
Coral bleaching, during which corals lose their symbiotic dinoflagellates, typically corresponds with periods of intense heat stress, and appears to be increasing in frequency and geographic extent as the climate warms. A fundamental question in coral reef ecology is whether chronic local stress reduces coral resistance and resilience from episodic stress such as bleaching, or alternatively promotes acclimatization, potentially increasing resistance and resilience. Here we show that following a major bleaching event, Montastraea faveolata coral growth rates at sites with higher local anthropogenic stressors remained suppressed for at least 8 years, while coral growth rates at sites with lower stress recovered in 2–3 years. Instead of promoting acclimatization, our data indicate that background stress reduces coral fitness and resilience to episodic events. We also suggest that reducing chronic stress through local coral reef management efforts may increase coral resilience to global climate change
Homozygosity at the MTL locus in clinical strains of Candida albicans: Karyotypic rearrangments and tetraploid formation
One hundred and twenty Candida albicans clinical isolates from the late 1980s and early 1990s were examined for homosygosity at the MTL locus. Of these, 108 were heterozygous (MTLa/MTLα), whereas seven were MTLa and five were MTLα. Five of the homozygous isolates were able to switch to the opaque cell morphology, while opaque cells were not detectable among the remaining seven. Nevertheless, all but one of the isolates homozygous at the MTL locus were shown to mate and to yield cells containing markers from both parents; the non-mater was found to have a frameshift in the MTLα1 gene. In contrast to Saccharomyces cerevisiae, C. albicans homozygotes with no active MTL allele failed to mate rather than mating as a cells. There was no correlation between homoxygosity and fluconazole resistance, mating and fluconazole resistance or switching and fluconazole resistance, in part because most of the strains were isolated before the widespread use of this antifungal agent, and only three were in fact drug resistant Ten of the 12 homozygotes had rearranged karyotypes involving one or more homologue of chromosomes 4, 5, 6 and 7. We suggest that karyotypic rearrangement, drug resistance and homozygosity come about as the result of induction of hyperrecombination during the infection process; hence, they tend to occur together, but each is the independent result of the same event. Furthermore, as clinical strains can mate and form tetraploids, mating and marker exchange are likely to be a significant part of the life cycle of C. albicans in vivo
Immunohistochemical expression and prognostic value of PD-L1 in Extrapulmonary small cell carcinoma: a single institution experience
BACKGROUND: Extrapulmonary small cell carcinomas (ESCC) are rare but aggressive tumors. Relapses are common despite treatment with chemotherapy and/or radiotherapy. Prospective data for treatment of ESCC are lacking; treatment of these cancers usually incorporates lung small cell carcinoma treatment recommendations. Cancer staging remains the most important prognostic factor. Cancer immunotherapy targeting the PD-1/PD-L1 pathway has shown efficacy in multiple tumor types, and could be an appealing treatment strategy for these rare tumors.
METHODS: We investigated PD-L1 expression by immunochemistry (IHC) in ESCCs diagnosed at University of Massachusetts Medical Center, from 1999 to 2016. 34 cases with sufficient material were selected for PD-L1 IHC analysis using clone E1L3N. PD-L1 expression was evaluated using the combined positive score (CPS). Retrospective chart review was performed. We evaluated the incidence and prognostic value of PD-L1 expression in ESCC at our institution.
RESULTS: Twelve out 34 cases (35%) had PD-L1 CPS scores \u3e /=1. Ten cases had CPS scores ranging 1-5, whereas 2 cases had CPS scores \u3e 80. The overall response rate to the standard chemotherapy with/without radiotherapy in the PD-L1 positive group was 80% versus 67% for the PDL-1 negative group (p-value 0.67). The median overall survival for the PD-L1 positive group, regardless of stage, was 11.5 months versus 7 months for PD-L1 negative group (p-value 0.34). Patients with limited stage disease with positive PD-L1 had a median survival of 53 months compared to 15 months for patients with PD-L1 negative limited stage (p-value 0.80).
CONCLUSIONS: This study showed that at least one third of our ESCC tissue samples expressed PD-L1. There was a trend for higher response rates to the standard chemotherapy with/without radiotherapy and improved survival in PD-L1 positive patients. Further studies are required to understand the implications of immune dysregulation in these aggressive tumors. PD-L1/PD-1 inhibitors should be investigated in this group of patients
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