Das Internet als Plattform politischer Interventionen: Ladyfeste im Netz

"In feministischen und queer-feministischen Debatten wird darum gerungen, wie komplexen Formationen von Diskriminierung, Ausgrenzung und Ausbeutung theoretisch und politisch begegnet werden kann. Der Blick in die aktivistische Praxis zeigt, dass Positionen, die in feministischen Theoriedebatten häufig als unvereinbar gelten, bereits produktiv innerhalb der einzelnen lokalen Szenen koexistieren. Eine solche Praxis ist die derzeit boomende Veranstaltungsart 'Ladyfest'. Ladyfeste finden nicht nur in alternativen Kulturzentren statt, sondern sie sind durch die Art ihrer virtuellen Präsenz ein globales Netzwerk geworden, dessen Ziel die politische Intervention in die verschiedenen Erscheinungsformen der Verschränkung von Macht und Geschlecht ist." (Autorenreferat

Modellprojekt zur Förderung einer Kooperation von Jugendhilfe und Schule "Schoolworker"

MODELLPROJEKT ZUR FÖRDERUNG EINER KOOPERATION VON JUGENDHILFE UND SCHULE "SCHOOLWORKER" Modellprojekt zur Förderung einer Kooperation von Jugendhilfe und Schule "Schoolworker" / Groß, Dirk (Rights reserved) ( -

Aktionsprogramm zur Eingliederung von benachteiligten Jugendlichen im Übergang Schule - Ausbildung - Beruf im Landkreis Saarlouis

AKTIONSPROGRAMM ZUR EINGLIEDERUNG VON BENACHTEILIGTEN JUGENDLICHEN IM ÜBERGANG SCHULE - AUSBILDUNG - BERUF IM LANDKREIS SAARLOUIS Aktionsprogramm zur Eingliederung von benachteiligten Jugendlichen im Übergang Schule - Ausbildung - Beruf im Landkreis Saarlouis / Groß, Dirk (Rights reserved) ( -

Plastic Fruit Stickers in Industrial Composting─Surface and Structural Alterations Revealed by Electron Microscopy and Computed Tomography

Often large quantities of plastics are found in compost, with price look-up stickers being a major but little-explored component in the contamination path. Stickers glued to fruit or vegetable peels usually remain attached to the organic material despite sorting processes in the composting plant. Here, we investigated the effects of industrial composting on the structural alterations of these stickers. Commercial polypropylene (PP) stickers on banana peels were added to a typical organic material mixture for processing in an industrial composting plant and successfully resampled after a prerotting (11 days) and main rotting step (25 days). Afterward, both composted and original stickers were analyzed for surface and structural changes via scanning electron microscopy, Fourier-transform infrared spectroscopy, and micro- and nano-X-ray computed tomography (CT) combined with deep learning approaches. The composting resulted in substantial surface changes and degradation in the form of microbial colonization, deformation, and occurrence of cracks in all stickers. Their pore volumes increased from 16.7% in the original sticker to 26.3% at the end of the compost process. In a similar way, the carbonyl index of the stickers increased. Micro-CT images additionally revealed structural changes in the form of large adhesions that penetrated the surface of the sticker. These changes were accompanied by delamination after 25 days of composting, thus overall hinting at the degradation of the stickers and the subsequent formation of smaller microplastic pieces

On the Use of Network Flow Techniques for Assigning Evacuees to Exits

We apply network flow techniques to find good exit selections for evacuees in an emergency evacuation. More precisely, we present two algorithms for computing exit distributions using both classical flows and flows over time which are well known from combinatorial optimization. The performance of these new proposals is compared to a simple shortest path approach and to a best response dynamics approach by using a cellular automaton model

Population genomic analysis of elongated skulls reveals extensive female-biased immigration in Early Medieval Bavaria

Modern European genetic structure demonstrates strong correlations with geography, while genetic analysis of prehistoric humans has indicated at least two major waves of immigration from outside the continent during periods of cultural change. However, population-level genome data that could shed light on the demographic processes occurring during the intervening periods have been absent. Therefore, we generated genomic data from 41 individuals dating mostly to the late 5th/early 6th century AD from present-day Bavaria in southern Germany, including 11 whole genomes (mean depth 5.56×). In addition we developed a capture array to sequence neutral regions spanning a total of 5 Mb and 486 functional polymorphic sites to high depth (mean 72×) in all individuals. Our data indicate that while men generally had ancestry that closely resembles modern northern and central Europeans, women exhibit a very high genetic heterogeneity; this includes signals of genetic ancestry ranging from western Europe to East Asia. Particularly striking are women with artificial skull deformations; the analysis of their collective genetic ancestry suggests an origin in southeastern Europe. In addition, functional variants indicate that they also differed in visible characteristics. This example of female-biased migration indicates that complex demographic processes during the Early Medieval period may have contributed in an unexpected way to shape the modern European genetic landscape. Examination of the panel of functional loci also revealed that many alleles associated with recent positive selection were already at modern-like frequencies in European populations ∼1,500 years ago

Improved upper limb function in non-ambulant children with SMA type 2 and 3 during nusinersen treatment: a prospective 3-years SMArtCARE registry study

Background The development and approval of disease modifying treatments have dramatically changed disease progression in patients with spinal muscular atrophy (SMA). Nusinersen was approved in Europe in 2017 for the treatment of SMA patients irrespective of age and disease severity. Most data on therapeutic efficacy are available for the infantile-onset SMA. For patients with SMA type 2 and type 3, there is still a lack of sufficient evidence and long-term experience for nusinersen treatment. Here, we report data from the SMArtCARE registry of non-ambulant children with SMA type 2 and typen 3 under nusinersen treatment with a follow-up period of up to 38 months. Methods SMArtCARE is a disease-specific registry with data on patients with SMA irrespective of age, treatment regime or disease severity. Data are collected during routine patient visits as real-world outcome data. This analysis included all non-ambulant patients with SMA type 2 or 3 below 18 years of age before initiation of treatment. Primary outcomes were changes in motor function evaluated with the Hammersmith Functional Motor Scale Expanded (HFMSE) and the Revised Upper Limb Module (RULM). Results Data from 256 non-ambulant, pediatric patients with SMA were included in the data analysis. Improvements in motor function were more prominent in upper limb: 32.4% of patients experienced clinically meaningful improvements in RULM and 24.6% in HFMSE. 8.6% of patients gained a new motor milestone, whereas no motor milestones were lost. Only 4.3% of patients showed a clinically meaningful worsening in HFMSE and 1.2% in RULM score. Conclusion Our results demonstrate clinically meaningful improvements or stabilization of disease progression in non-ambulant, pediatric patients with SMA under nusinersen treatment. Changes were most evident in upper limb function and were observed continuously over the follow-up period. Our data confirm clinical trial data, while providing longer follow-up, an increased number of treated patients, and a wider range of age and disease severity