1,772 research outputs found
Sedimentología de la Formación Calizas con oncolitos de Higueruelas (Malm) en la región de Muel-Belchite (Provincia de Zaragoza)
El estudio sedimentológico de la Formación Higueruelas (Malm) en la región de Muel-Belchite, permite definir un ciclo regresivo con gran variedad de facies y ambientes, con desarrollo en la plataforma interna de montículos algales y coralinos, y sedimentación oolítica litoral
Building from Within: How Two Female Prisoners Survived Incarceration
According to the US Commission of Civil Rights, from 1980 to 2016, the percentage of imprisoned women surpassed 730% (4). Severe isolation, lack of sunlight, and sensory deprivation tactics were employed during the 1980s, when Silvia Baraldini and Laura Whitehorn were incarcerated at the federal women’s prison in Lexington, Kentucky. Both women maintained their basic humanity and spirit by creating educational opportunities for fellow inmates, advocating for improved conditions, and sharing their experiences through letter writing. They each wrote hundreds of letters to friends, family, and other social activists concerned with their plight. Using a collection of letters written by Baraldini and Whitehorn, dating from 1987 to 2000, now part of the Kate Black Social Activism Papers at the University of Kentucky Libraries Special Collections Research Center, this research will explore the work, activity, and mental health of these women during their incarceration. While Whitehorn was mainly concerned with health education, especially regarding the burgeoning health crisis of HIV and AIDS, Baraldini’s advocacy focused on reform of current incarceration tactics, like the High Security Unit in the Lexington prison. Because of Baraldini’s efforts, with support from Amnesty International, the High Security Unit at Lexington’s Federal Correctional Institution was shut down in 1988. This research relates Baraldini and Whitehorn’s activism to studies on how prison systems treat women prisoners differently than male prisoners, whether they receive more extreme punishments, and the nature of those punishments. In light of the current prison system, Baraldini and Whitehorn offer examples of how women maintain their humanity while incarcerated
Effect of Antioxidants in Cathepsin B Release by HIV Infected Macrophages
During HIV infection of macrophages, the lysosomal protein cathepsin B is released and induces neurotoxicity. Also, the levels of cathepsin B are increased in plasma and post-mortem brain tissue of patients with HIV-associated dementia. Oxidative damage is increased in HIV- infected patients, while antioxidants are decreased in HIV-associated dementia. Dimethyl fumarate (DMF), an antioxidant, has been reported to decrease HIV replication and neurotoxicity caused by HIV-infected macrophages. Since HIV also increases cathepsin B, we hypothesize that DMF will also reduce cathepsin B release from HIV-infected macrophages. Monocyte-derived macrophages (MDM) were isolated from healthy donors and inoculated with HIV-1ADA. After removal of infection, MDM were treated with DMF at different concentrations (15, 30, and 60 µM) until day 12 post-infection, changing and collecting media every three days. HIV-1p24 and cathepsin B levels were assessed from HIV-infected MDM supernatants at the end of cultures using ELISA. Results indicate that DMF reduced HIV-1 replication and cathepsin B secretion from HIV-infected macrophages, in a concentration-dependent manner, in comparison with vehicle (DMSO)-treated controls. However, cathepsin B secretion was not affected by HIV infection in vehicle-treated controls. In conclusion, DMSO may have had an unexpected effect in cathepsin B secretion in our experiments, and this could explain why cathepsin B secretion was not affected by HIV infection. Future experiments will include an untreated control group to determine if DMSO vehicle is having an effect in cathepsin B secretion. This will lead us to determine the role of DMF in cathepsin B secretion from HIV-infected macrophages
Chemical similarities between Galactic bulge and local thick disk red giant stars
The evolution of the Milky Way bulge and its relationship with the other
Galactic populations is still poorly understood. The bulge has been suggested
to be either a merger-driven classical bulge or the product of a dynamical
instability of the inner disk. To probe the star formation history, the initial
mass function and stellar nucleosynthesis of the bulge, we performed an
elemental abundance analysis of bulge red giant stars. We also completed an
identical study of local thin disk, thick disk and halo giants to establish the
chemical differences and similarities between the various populations.
High-resolution infrared spectra of 19 bulge giants and 49 comparison giants in
the solar neighborhood were acquired with Gemini/Phoenix. All stars have
similar stellar parameters but cover a broad range in metallicity. A standard
1D local thermodynamic equilibrium analysis yielded the abundances of C, N, O
and Fe. A homogeneous and differential analysis of the bulge, halo, thin disk
and thick disk stars ensured that systematic errors were minimized. We confirm
the well-established differences for [O/Fe] (at a given metallicity) between
the local thin and thick disks. For the elements investigated, we find no
chemical distinction between the bulge and the local thick disk, which is in
contrast to previous studies relying on literature values for disk dwarf stars
in the solar neighborhood. Our findings suggest that the bulge and local thick
disk experienced similar, but not necessarily shared, chemical evolution
histories. We argue that their formation timescales, star formation rates and
initial mass functions were similar.Comment: Accepted for publication in A&A, 5 page
Is the solar spectrum latitude dependent? An investigation with SST/TRIPPEL
Context: In studies of the solar spectrum relative to spectra of solar twin
stars, it has been found that the chemical composition of the Sun seems to
depart systematically from those of the twins. One possible explanation is that
the effect is due to the special aspect angle of the Sun when observed from
Earth, as compared with the aspect angles of the twins. Thus, a latitude
dependence of the solar spectrum, even with the heliocentric angle constant,
could lead to effects of the type observed.
Aim: We explore a possible variation in the strength of certain spectral
lines, used in the comparisons between the composition of the Sun and the
twins, at loci on the solar disk with different latitudes but at constant
heliocentric angle.
Methods: We use the TRIPPEL spectrograph at the Swedish 1-m Solar Telescope
on La Palma to record spectra in five spectral regions in order to compare
different locations on the solar disk at a heliocentric angle of 45 deg.
Equivalent widths and other parameters are measured for fifteen different lines
representing nine atomic species.
Results: The relative variations in equivalent widths at the equator and at
solar latitude 45 deg are found to be less than 1.5 % for all spectral lines
studied. Translated to elemental abundances as they would be measured from a
terrestrial and a hypothetical pole-on observer, the difference is estimated to
be within 0.005 dex in all cases.
Conclusion: It is very unlikely that latitude effects could cause the
reported abundance difference between the Sun and the solar twins. The accuracy
obtainable in measurements of small differences in spectral line strengths
between different solar disk positions is very high.Comment: 9 pages, 10 figures, accepted by Astronomy & Astrophysic
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