94 research outputs found

    Coherent states of non-relativistic electron in magnetic-solenoid field

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    We construct coherent states of a nonrelativistic electron in the magnetic-solenoid field, which is a superposition of the Aharonov-Bohm field and a collinear uniform magnetic field. In the problem under consideration there are two kind of coherent states, the first kind corresponds to classical trajectories which embrace the solenoid and the second one to trajectories which do not. Mean coordinates in the constructed coherent states are moving along classical trajectories, the coherent states maintain their form under the time evolution, and represent a complete set of functions, which can be useful in semi classical calculations. In the absence of the Aharonov-Bohm filed these states are reduced to the well-known in the case of uniform magnetic field Malkin-Man'ko coherent states.Comment: 11 pages, version accepted for publication in J. Phys. A, 3 figures adde

    Potential use of vitiviniculture waste in mixed cactus pear silages with elephant grass in lamb diet.

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    The aim was to evaluate intake, digestibility, water balance, nitrogen balance, ingestive behavior, performance, and carcass traits of lambs on diets containing levels of vitiviniculture waste in mixed cactus pear silages with elephant grass. Twenty-four crossbred male lambs (150 days of age, 20.75 kg ± 1.33 kg body weight) were assigned to a randomized block design, with four treatments (diets) and six animals per treatment. The experimental diets consisted of four elephant grass mixed silages (MS), containing different levels of cactus pear and vitiviniculture waste: MS1 – 255 g/kg cactus pear and 108 g/kg vitiviniculture waste; MS2 – 216 g/kg cactus pear and 144 g/kg vitiviniculture waste; MS3 – 180 g/kg cactus pear and 180 g/kg vitiviniculture waste; MS4 – 144 g/kg cactus pear and 216 g/kg vitiviniculture waste, on a dry matter basis (DM). The experiment lasted 86 days, preceded by 20 days of adaptation. The inclusion of vitiviniculture waste in silages resulted in a quadratic effect for intakes of crude protein, neutral detergent fiber, acid detergent fiber, and total carbohydrates, digestibility of DM and ether extract, metabolizable water, and water balance (P < 0.05), with the highest values of intake and digestibility observed in lambs fed on MS2. The MS in diets resulted in a reduction in the carcass conformation of the lambs (P = 0.034). Under the experimental conditions, the use of up to 144 g/kg vitiviniculture waste in the composition of mixed cactus pear and elephant grass silages (MS2) in diets for confined lamb as it provides greater nutrient intake and dry matter digestibility

    Differential gene expression associated with soybean oil level in the diet of pigs.

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    The aim of this study was to identify the differentially expressed genes (DEG) from the skeletal muscle and liver samples of animal models for metabolic diseases in humans. To perform the study, the fatty acid (FA) profile and RNA sequencing (RNA-Seq) data of 35 samples of liver tissue (SOY1.5, n = 17 and SOY3.0, n = 18) and 36 samples of skeletal muscle (SOY1.5, n = 18 and SOY3.0, n = 18) of Large White pigs were analyzed. The FA profile of the tissues was modified by the diet, mainly those related to monounsaturated (MUFA) and polyunsaturated (PUFA) FA. The skeletal muscle transcriptome analysis revealed 45 DEG (FDR 10%), and the functional enrichment analysis identified network maps related to inflammation, immune processes, and pathways associated with oxidative stress, type 2 diabetes, and metabolic dysfunction. For the liver tissue, the transcriptome profile analysis revealed 281 DEG, which participate in network maps related to neurodegenerative diseases. With this nutrigenomics study, we verified that different levels of soybean oil in the pig diet, an animal model for metabolic diseases in humans, affected the transcriptome profile of skeletal muscle and liver tissue. These findings may help to better understand the biological mechanisms that can be modulated by the diet

    The impact of maternal HIV infection on cord blood lymphocyte subsets and cytokine profile in exposed non-infected newborns

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    <p>Abstract</p> <p>Background</p> <p>Children born to HIV+ mothers are exposed intra-utero to several drugs and cytokines that can modify the developing immune system, and influence the newborn's immune response to infections and vaccines. We analyzed the relation between the distribution of cord blood lymphocyte subsets and cytokine profile in term newborns of HIV+ mothers using HAART during pregnancy and compared them to normal newborns.</p> <p>Methods</p> <p>In a prospective, controlled study, 36 mother-child pairs from HIV+ mothers and 15 HIV-uninfected mothers were studied. Hematological features and cytokine profiles of mothers at 35 weeks of pregnancy were examined. Maternal and cord lymphocyte subsets as well as B-cell maturation in cord blood were analyzed by flow cytometry. The non-stimulated, as well as BCG- and PHA-stimulated production of IL2, IL4, IL7, IL10, IL12, IFN-γ and TNF-alpha in mononuclear cell cultures from mothers and infants were quantified using ELISA.</p> <p>Results</p> <p>After one year follow-up none of the exposed infants became seropositive for HIV. An increase in B lymphocytes, especially the CD19/CD5+ ones, was observed in cord blood of HIV-exposed newborns. Children of HIV+ hard drug using mothers had also an increase of immature B-cells. Cord blood mononuclear cells of HIV-exposed newborns produced less IL-4 and IL-7 and more IL-10 and IFN-γ in culture than those of uninfected mothers. Cytokine values in supernatants were similar in infants and their mothers except for IFN-γ and TNF-alpha that were higher in HIV+ mothers, especially in drug abusing ones. Cord blood CD19/CD5+ lymphocytes showed a positive correlation with cord IL-7 and IL-10. A higher maternal age and smoking was associated with a decrease of cord blood CD4+ cells.</p> <p>Conclusions</p> <p>in uninfected infants born to HIV+ women, several immunological abnormalities were found, related to the residual maternal immune changes induced by the HIV infection and those associated with antiretroviral treatment. Maternal smoking was associated to changes in cord CD3/CD4 lymphocytes and maternal hard drug abuse was associated with more pronounced changes in the cord B cell line.</p
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