Sorgo granífero (Sorghum bicolor (L.) Moench) de alta lisina no Brasil.

Pequenas quantidades de sementes de duas linhagens de sorgo, com um gene recessivo simples para lisina, descoberto recentemente na Colecao Mundial de Sorgos da Universidade de Purdue, West Lafayette, Indiana, U.S.A., foram plantas para multiplicacao de sementes pela EMBRAPA e pela EPAMIG em Sete Lagoas, Minas Gerais. As linhagens mostraram nao adaptadas, com porte alto, maturidade tardia e susceptibilidade a doencas. Sementes geneticas de duas linhagens de alta lisina e algumas selecoes de porte baixo e precoce poderao ser requisitadas. As propriedades quimicas e biologicas do sorgo com o mutante para alta lisina foram previamente revisadas

Endoscopic diagnosis of an intramural hematoma presenting as an anticoagulant ileus

info:eu-repo/semantics/publishedVersio

Comparativo dos registros meteorológicos das estações automáticas da Fundação Procafé e do Instituto Nacional de Meteorologia (Inmet).

O objetivo deste estudo foi a comparação dos dados coletados pelas duas estações, entre dezembro de 2006 e agosto de 2014, avaliando o grau de associação entre as variáveis

Primary Central Nervous System Lymphoma Mimicking the Presentation of Pituitary Apoplexy: A Case Report

Pituitary lymphoma is one of the rare variants of primary central nervous system lymphoma (PCNSL), mostly arising due to the metastatic spread of systemic lymphoma. We report the case of a 69-year-old woman who initially presented to her family physician with a headache but without any other symptoms. The MRI scan revealed a sellar mass consistent with a pituitary macroadenoma. When the patient was referred to our hospital, two weeks later, the symptoms had progressed, comprising complete right-sided ophthalmoplegia and ptosis, with left-sided amaurosis. A repeat MRI revealed an increased size of the sellar mass, consistent with pituitary apoplexy. A right pterional craniotomy with partial resection of the mass was performed and an intraoperative frozen section biopsy was carried out. The final pathology revealed diffuse large B-cell lymphoma. A systemic follow-up including a whole-body CT, bone marrow aspiration, and cerebrospinal fluid studies ruled out any systemic manifestation, and the patient was HIV-negative. The patient underwent treatment with methotrexate, cytarabine, thiotepa, and rituximab for PCNSL. Although rare, PCNSL can mimic pituitary apoplexy, which needs to be considered if conservative therapy or surgery is to be offered to a patient with a radiological and clinical diagnosis of pituitary apoplexy.info:eu-repo/semantics/publishedVersio

Core Stabilization Exercise Prescription, Part I: Current Concepts in Assessment and Intervention

Context: Injury to the low back can cause significant pain and dysfunction, which can affect an athlete’s performance and result in time lost from sport. A common conservative treatment is therapeutic core stabilization exercises, which can address pain and musculoskeletal dysfunction in patients with low back pathology. Evidence Acquisition: MEDLINE and CINAHL were searched (from 1966 to March 2013) to identify relevant research. Keywords and keyword combinations searched included motor control exercise, segmental stabilization, core stabilization, transversus abdominis, multifidi, and low back pain. Results: There are 2 popular rehabilitation strategies to assess core function and promote core stabilization. Each has been developed based on biomechanical models of lumbar segmental stability and observed motor control dysfunction in patients with low back pain. Conclusion: Controversy exists among clinical and research groups as to the optimal strategy for an athlete with low back pain

Core Stabilization Exercise Prescription, Part 2: A Systematic Review of Motor Control and General (Global) Exercise Rehabilitation Approaches for Patients with Low Back Pain

Context: Therapeutic exercises are frequently prescribed to patients with low back pain. Numerous exercise programs for patients with low back pain have been described. Many of these treatment programs are based on 1 of 2 popular rehabilitation strategies: a motor control exercise approach or a general exercise approach. Data Sources: PubMed clinical queries from 1966 to March 2013 for keyword combinations including motor control exercise, core stability exercise, therapeutic exercise, general exercise, global exercise, local exercise, transversus abdominis, segmental stabilization, and low back pain. Study Selection: Randomized controlled trials that assessed the effects of a motor control exercise approach, a general exercise approach, or both for patients with low back pain that were published in scientific peer-reviewed journals. Data Extraction: Included studies underwent appraisal for exercise intervention and outcomes. Results: Fifteen studies were identified (8, motor control exercise approach without general exercise comparison; 7, general exercise approach with or without motor control exercise approach comparison). Current evidence suggests that exercise interventions may be effective at reducing pain or disability in patients with low back pain. Conclusion: Stabilization exercises for patients with low back pain may help to decrease pain and disability. It may not be necessary to prescribe exercises purported to restore motor control of specific muscles

Qualidade dos dados meteorológicos utilizados em sistema de alerta da ferrugem do cafeeiro.

O projeto de Iniciação Científica tem o objetivo de avaliar os dados de estações meteorológicas automáticas, recebidos mensalmente, visando aumentar a sua consistência.CIIC 2014. N° 14601

Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins

O[superscript 6]-methylguanine DNA methyltransferase (MGMT) suppresses mutations and cell death that result from alkylation damage. MGMT expression is lost by epigenetic silencing in a variety of human cancers including nearly half of sporadic colorectal cancers, suggesting that this loss maybe causal. Using mice with a targeted disruption of the Mgmt gene, we tested whether Mgmt protects against azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF), against AOM and dextran sulfate sodium (DSS)-induced colorectal adenomas and against spontaneous intestinal adenomas in Apc[superscript Min] mice. We also examined the genetic interaction of the Mgmt null gene with a DNA mismatch repair null gene, namely Msh6. Both Mgmt and Msh6 independently suppress AOM-induced ACF, and combination of the two mutant alleles had a multiplicative effect. This synergism can be explained entirely by the suppression of alkylation-induced apoptosis when Msh6 is absent. In addition, following AOM+DSS treatment Mgmt protected against adenoma formation to the same degree as it protected against AOM-induced ACF formation. Finally, Mgmt deficiency did not affect spontaneous intestinal adenoma development in Apc[superscript Min/+] mice, suggesting that Mgmt suppresses intestinal cancer associated with exogenous alkylating agents, and that endogenous alkylation does not contribute to the rapid tumor development seen in Apc[superscript Min/+] mice.National Institutes of Health (U.S.) (grant ES02109)National Institutes of Health (U.S.) (grant CA75576)American Cancer Society (Research Professor

Vanishing value chains, industrial districts and HRM in the Brazilian automotive industry

Industrial districts in the Brazilian automotive industry have facilitated just-in-time production, functional flexibility, and compatibility of HR practices since the 1980s. However, this model has been threatened by global over-capacity and the rise of low cost suppliers in South Korea and China. This paper develops literature on proximity dynamics though exploring the influence of global supply chains on HRM in industrial districts. The more specific research questions are: How viable are industrial districts in the context of global crises? And how is this viability bound up with the awareness of HR practices down the supply chain? The findings indicate that the industrial districts model is under threat. In the context of global supply chains, automotive majors have shifted costs onto their suppliers, disrupting established relationships, and moreover, they often lack knowledge of the employment practices of distant suppliers. Yet, in times of political and economic uncertainty, worker rights might be best served by geographical and cognitive proximity