513 research outputs found
Picosecond fluctuating protein energy landscape mapped by pressure–temperature molecular dynamics simulation
Microscopic statistical pressure fluctuations can, in principle, lead to corresponding fluctuations in the shape of a protein energy landscape. To examine this, nanosecond molecular dynamics simulations of lysozyme are performed covering a range of temperatures and pressures. The well known dynamical transition with temperature is found to be pressure-independent, indicating that the effective energy barriers separating conformational substates are not significantly influenced by pressure. In contrast, vibrations within substates stiffen with pressure, due to increased curvature of the local harmonic potential in which the atoms vibrate. The application of pressure is also shown to selectively increase the damping of the anharmonic, low-frequency collective modes in the protein, leaving the more local modes relatively unaffected. The critical damping frequency, i.e., the frequency at which energy is most efficiently dissipated, increases linearly with pressure. The results suggest that an invariant description of protein energy landscapes should be subsumed by a fluctuating picture and that this may have repercussions in, for example, mechanisms of energy dissipation accompanying functional, structural, and chemical relaxation
Dynamic validation of the Planck/LFI thermal model
The Low Frequency Instrument (LFI) is an array of cryogenically cooled
radiometers on board the Planck satellite, designed to measure the temperature
and polarization anisotropies of the cosmic microwave backgrond (CMB) at 30, 44
and 70 GHz. The thermal requirements of the LFI, and in particular the
stringent limits to acceptable thermal fluctuations in the 20 K focal plane,
are a critical element to achieve the instrument scientific performance.
Thermal tests were carried out as part of the on-ground calibration campaign at
various stages of instrument integration. In this paper we describe the results
and analysis of the tests on the LFI flight model (FM) performed at Thales
Laboratories in Milan (Italy) during 2006, with the purpose of experimentally
sampling the thermal transfer functions and consequently validating the
numerical thermal model describing the dynamic response of the LFI focal plane.
This model has been used extensively to assess the ability of LFI to achieve
its scientific goals: its validation is therefore extremely important in the
context of the Planck mission. Our analysis shows that the measured thermal
properties of the instrument show a thermal damping level better than
predicted, therefore further reducing the expected systematic effect induced in
the LFI maps. We then propose an explanation of the increased damping in terms
of non-ideal thermal contacts.Comment: Planck LFI technical papers published by JINST:
http://www.iop.org/EJ/journal/-page=extra.proc5/1748-022
Measurements of Anisotropy in the Cosmic Microwave Background Radiation at 0.5 Degree Angular Scales Near the Star Gamma Ursae Minoris
We present results from a four frequency observation of a 6 x 0.6 degree
strip of the sky centered near the star Gamma Ursae Minoris during the fourth
flight of the Millimeter-wave Anisotropy eXperiment (MAX). The observation was
made with a 1.4 degree peak-to-peak sinusoidal chop in all bands. The FWHM beam
sizes were 0.55 +/- 0.05 degrees at 3.5 cm-1 and 0.75 +/-0.05 degrees at 6, 9,
and 14 cm-1. During this observation significant correlated structure was
observed at 3.5, 6 and 9 cm-1 with amplitudes similar to those observed in the
GUM region during the second and third flights of MAX. The frequency spectrum
is consistent with CMB and inconsistent with thermal emission from interstellar
dust. The extrapolated amplitudes of synchrotron and free-free emission are too
small to account for the amplitude of the observed structure. If all of the
structure is attributed to CMB anisotropy with a Gaussian autocorrelation
function and a coherence angle of 25', then the most probable values of
DeltaT/TCMB in the 3.5, 6, and 9 cm-1 bands are 4.3 (+2.7, -1.6) x 10-5, 2.8
(+4.3, -1.1) x 10-5, and 3.5 (+3.0, -1.6) x 10-5 (95% confidence upper and
lower limits), respectively.Comment: 16 pages, postscrip
Measurements of Anisotropy in the Cosmic Microwave Background Radiation at Degree Angular Scales Near the Stars Sigma Hercules and Iota Draconis
We present results from two four-frequency observations centered near the
stars Sigma Hercules and Iota Draconis during the fourth flight of the
Millimeter-wave Anisotropy eXperiment (MAX). The observations were made of 6 x
0.6-degree strips of the sky with 1.4-degree peak to peak sinusoidal chop in
all bands. The FWHM beam sizes were 0.55+/-0.05 degrees at 3.5 cm-1 and a
0.75+/-0.05 degrees at 6, 9, and 14 cm-1. Significant correlated structures
were observed at 3.5, 6 and 9 cm-1. The spectra of these signals are
inconsistent with thermal emission from known interstellar dust populations.
The extrapolated amplitudes of synchrotron and free-free emission are too small
to account for the amplitude of the observed structures. If the observed
structures are attributed to CMB anisotropy with a Gaussian autocorrelation
function and a coherence angle of 25', then the most probable values are
DT/TCMB = (3.1 +1.7-1.3) x 10^-5 for the Sigma Hercules scan, and DT/TCMB =
(3.3 +/- 1.1) x 10^-5 for the Iota Draconis scan (95% confidence upper and
lower limits). Finally a comparison of all six MAX scans is presented.Comment: 13 pages, postscript file, 2 figure
Planck-LFI radiometers tuning
"This paper is part of the Prelaunch status LFI papers published on JINST:
http://www.iop.org/EJ/journal/-page=extra.proc5/jinst"
This paper describes the Planck Low Frequency Instrument tuning activities
performed through the ground test campaigns, from Unit to Satellite Levels.
Tuning is key to achieve the best possible instrument performance and tuning
parameters strongly depend on thermal and electrical conditions. For this
reason tuning has been repeated several times during ground tests and it has
been repeated in flight before starting nominal operations. The paper discusses
the tuning philosophy, the activities and the obtained results, highlighting
developments and changes occurred during test campaigns. The paper concludes
with an overview of tuning performed during the satellite cryogenic test
campaign (Summer 2008) and of the plans for the just started in-flight
calibration.Comment: This is an author-created, un-copyedited version of an article
accepted for publication in JINST. IOP Publishing Ltd is not responsible for
any errors or omissions in this version of the manuscript or any version
derived from it. The definitive publisher authenticated version is available
online at http://dx.doi.org/10.1088/1748-0221/4/12/T12013
The Imprint of Gravitational Waves on the Cosmic Microwave Background
Long-wavelength gravitational waves can induce significant temperature
anisotropy in the cosmic microwave background. Distinguishing this from
anisotropy induced by energy density fluctuations is critical for testing
inflationary cosmology and theories of large-scale structure formation. We
describe full radiative transport calculations of the two contributions and
show that they differ dramatically at angular scales below a few degrees. We
show how anisotropy experiments probing large- and small-angular scales can
combine to distinguish the imprint due to gravitational waves.Comment: 11 pages, Penn Preprint-UPR-
Determination of Inflationary Observables by Cosmic Microwave Background Anisotropy Experiments
Inflation produces nearly Harrison-Zel'dovich scalar and tensor perturbation
spectra which lead to anisotropy in the cosmic microwave background (CMB). The
amplitudes and shapes of these spectra can be parametrized by , , and where and are the scalar and
tensor contributions to the square of the CMB quadrupole and and
are the power-lawspectral indices. Even if we restrict ourselves to information
from angles greater than one third of a degree, three of these observables can
be measured with some precision. The combination can be
known to better than . The scalar index can be determined to
better than . The ratio can be known to about for and slightly better for smaller . The precision with which
can be measured depends weakly on and strongly on . For
can be determined with a precision of about . A
full-sky experiment with a beam using technology available today, similar
to those being planned by several groups, can achieve the above precision. Good
angular resolution is more important than high signal-to-noise ratio; for a
given detector sensitivity and observing time a smaller beam provides
significantly more information than a larger beam. The uncertainties in
and are roughly proportional to the beam size. We briefly discuss the
effects of uncertainty in the Hubble constant, baryon density, cosmological
constant and ionization history.Comment: 28 pages of uuencoded postscript with 8 included figures. A
postscript version is also available by anonymous ftp at
ftp://astro.uchicago.edu/pub/astro/knox/fullsim.p
Advanced modelling of the Planck-LFI radiometers
The Low Frequency Instrument (LFI) is a radiometer array covering the 30-70
GHz spectral range on-board the ESA Planck satellite, launched on May 14th,
2009 to observe the cosmic microwave background (CMB) with unprecedented
precision. In this paper we describe the development and validation of a
software model of the LFI pseudo-correlation receivers which enables to
reproduce and predict all the main system parameters of interest as measured at
each of the 44 LFI detectors. These include system total gain, noise
temperature, band-pass response, non-linear response. The LFI Advanced RF Model
(LARFM) has been constructed by using commercial software tools and data of
each radiometer component as measured at single unit level. The LARFM has been
successfully used to reproduce the LFI behavior observed during the LFI
ground-test campaign. The model is an essential element in the database of LFI
data processing center and will be available for any detailed study of
radiometer behaviour during the survey.Comment: 21 pages, 15 figures, this paper is part of the Prelaunch status LFI
papers published on JINST:
http://www.iop.org/EJ/journal/-page=extra.proc5/jins
Thermal susceptibility of the Planck-LFI receivers
This paper is part of the Prelaunch status LFI papers published on JINST:
http://www.iop.org/EJ/journal/-page=extra.proc5/jinst .
This paper describes the impact of the Planck Low Frequency Instrument front
end physical temperature fluctuations on the output signal. The origin of
thermal instabilities in the instrument are discussed, and an analytical model
of their propagation and impact on the receivers signal is described. The
experimental test setup dedicated to evaluate these effects during the
instrument ground calibration is reported together with data analysis methods.
Finally, main results obtained are discussed and compared to the requirements.Comment: This is an author-created, un-copyedited version of an article
accepted for publication in Journal of Instrumentation. IOP Publishing Ltd is
not responsible for any errors or omissions in this version of the manuscript
or any version derived from it. The definitive publisher authenticated
version is available online at 10.1088/1748-0221/4/12/T1201
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