Expanding the role of impurity spectroscopy for investigating the physics of high-Z dissipative divertors

New techniques that attempt to more fully exploit spectroscopic diagnostics in the divertor and pedestal region during highly dissipative scenarios are demonstrated using experimental results from recent low-Z seeding experiments on Alcator C-Mod, JET and ASDEX Upgrade. To exhaust power at high parallel heat flux, q ‖ > 1 GW/m 2 , while minimizing erosion, reactors with solid, high-Z plasma facing components (PFCs) are expected to use extrinsic impurity seeding. Due to transport and atomic physics processes which impact impurity ionization balance, so-called ‘non-coronal’ effects, we do not accurately know and have yet to demonstrate the maximum q ‖ which can be mitigated in a tokamak. Radiation enhancement for nitrogen is shown to arise primarily from changes in Li- and Be-like charge states on open field lines, but also through transport-driven enhancement of H- and He-like charge states in the pedestal region. Measurements are presented from nitrogen seeded H-mode and L-mode plasmas where emission from N 1+ through N 6+ are observed. Active charge exchange spectroscopy of partially ionized low-Z impuri- ties in the plasma edge is explored to measure N 5+ and N 6+ within the confined plasma, while passive UV and visible spectroscopy is used to measure N 1+ -N 4+ in the boundary. Examples from recent JET and Alcator C-Mod experiments which employ nitrogen seeding highlight how improving spectroscopic cov- erage can be used to gain empirical insight and provide more data to validate boundary simulations.EURATOM 63305

Effect of toroidal field ripple on plasma rotation in JET

Dedicated experiments on TF ripple effects on the performance of tokamak plasmas have been carried out at JET. The TF ripple was found to have a profound effect on the plasma rotation. The central Mach number, M, defined as the ratio of the rotation velocity and the thermal velocity, was found to drop as a function of TF ripple amplitude (3) from an average value of M = 0.40-0.55 for operations at the standard JET ripple of 6 = 0.08% to M = 0.25-0.40 for 6 = 0.5% and M = 0.1-0.3 for delta = 1%. TF ripple effects should be considered when estimating the plasma rotation in ITER. With standard co-current injection of neutral beam injection (NBI), plasmas were found to rotate in the co-current direction. However, for higher TF ripple amplitudes (delta similar to 1%) an area of counter rotation developed at the edge of the plasma, while the core kept its co-rotation. The edge counter rotation was found to depend, besides on the TF ripple amplitude, on the edge temperature. The observed reduction of toroidal plasma rotation with increasing TF ripple could partly be explained by TF ripple induced losses of energetic ions, injected by NBI. However, the calculated torque due to these losses was insufficient to explain the observed counter rotation and its scaling with edge parameters. It is suggested that additional TF ripple induced losses of thermal ions contribute to this effect

Imaging Fourier transform spectrometers for environmental sensing

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77073/1/AIAA-1998-291-523.pd

Control System for the Holifield Radioactive Ion Beam Facility

A new accelerator control system is being impfemented as part of the development of the Holifield Radioactive Ion Beam Facility (HRIBF), a first generation radioactive ion beam (RIB) facility. The pre-existing accelerator control systems are based on 1970's technology and addition or alteration of controls is cumbersome and costly. A new, unified control system for the cyclotron and tandem accelerators. the RIB injector, ion sources, and accelerator beam lines is based on a commercial product from Vista Control Systems. Inc. Several other accelerator facilities. as well as numerous industrial sites, are now using this system. The control system is distributed over a number of computers which communicate over Ethernet and is easily extensible. Presently. implementation at the HRIBF is based on VAXNMS. VAX/ELN, VME, and Allen-Bradley PLCS programmable logic controller architectures. Expansion to include UMX platforms and CAMAC hardware support is planned. Operator interface is via X-terminals. The system has proven to be quite powerful, yet it has been easy to implement with a small staff. A Vista users group has resulted in shared software to implement specific controls. This paper details present system features and future implementations at the HRIBF

Genome-Wide Association with Select Biomarker Traits in the Framingham Heart Study

BACKGROUND: Systemic biomarkers provide insights into disease pathogenesis, diagnosis, and risk stratification. Many systemic biomarker concentrations are heritable phenotypes. Genome-wide association studies (GWAS) provide mechanisms to investigate the genetic contributions to biomarker variability unconstrained by current knowledge of physiological relations. METHODS: We examined the association of Affymetrix 100K GeneChip single nucleotide polymorphisms (SNPs) to 22 systemic biomarker concentrations in 4 biological domains: inflammation/oxidative stress; natriuretic peptides; liver function; and vitamins. Related members of the Framingham Offspring cohort (n = 1012; mean age 59 ± 10 years, 51% women) had both phenotype and genotype data (minimum-maximum per phenotype n = 507–1008). We used Generalized Estimating Equations (GEE), Family Based Association Tests (FBAT) and variance components linkage to relate SNPs to multivariable-adjusted biomarker residuals. Autosomal SNPs (n = 70,987) meeting the following criteria were studied: minor allele frequency ≥ 10%, call rate ≥ 80% and Hardy-Weinberg equilibrium p ≥ 0.001. RESULTS: With GEE, 58 SNPs had p < 10-6: the top SNPs were rs2494250 (p = 1.00*10-14) and rs4128725 (p = 3.68*10-12) for monocyte chemoattractant protein-1 (MCP1), and rs2794520 (p = 2.83*10-8) and rs2808629 (p = 3.19*10-8) for C-reactive protein (CRP) averaged from 3 examinations (over about 20 years). With FBAT, 11 SNPs had p < 10-6: the top SNPs were the same for MCP1 (rs4128725, p = 3.28*10-8, and rs2494250, p = 3.55*10-8), and also included B-type natriuretic peptide (rs437021, p = 1.01*10-6) and Vitamin K percent undercarboxylated osteocalcin (rs2052028, p = 1.07*10-6). The peak LOD (logarithm of the odds) scores were for MCP1 (4.38, chromosome 1) and CRP (3.28, chromosome 1; previously described) concentrations; of note the 1.5 support interval included the MCP1 and CRP SNPs reported above (GEE model). Previous candidate SNP associations with circulating CRP concentrations were replicated at p < 0.05; the SNPs rs2794520 and rs2808629 are in linkage disequilibrium with previously reported SNPs. GEE, FBAT and linkage results are posted at . CONCLUSION: The Framingham GWAS represents a resource to describe potentially novel genetic influences on systemic biomarker variability. The newly described associations will need to be replicated in other studies.National Heart, Lung, and Blood Institute's Framingham Heart Study (N01-HC25195); National Institutes of Health National Center for Research Resources Shared Instrumentation grant (1S10RR163736-01A1); National Institutes of Health (HL064753, HL076784, AG028321, HL71039, 2 K24HL04334, 1K23 HL083102); Doris Duke Charitable Foundation; American Diabetes Association Career Developement Award; National Center for Research Resources (GCRC M01-RR01066); US Department of Agriculture Agricultural Research Service (58-1950-001, 58-1950-401); National Institute of Aging (AG14759

Diabetes Risk Perception and Intention to Adopt Healthy Lifest yles Among Primary Care Patients

OBJECTIVE—To examine perceived risk of developing diabetes in primary care patients. RESEARCH DESIGN AND METHODS—We recruited 150 nondiabetic primary care patients. We made standard clinical measurements, collected fasting blood samples, and used the validated Risk Perception Survey for Developing Diabetes questionnaire. RESULTS—Patients with high perceived risk were more likely than those with low perceived risk to have a family history of diabetes (68 vs. 18%; P < 0.0001) and to have metabolic syndrome (53 vs. 35%; P = 0.04). However, patients with high perceived risk were not more likely to have intentions to adopt healthier lifestyle in the coming year (high 26.0% vs. low 29.2%; P = 0.69). CONCLUSIONS—Primary care patients with higher perceived risk of diabetes were at higher actual risk but did not express greater intention to adopt healthier lifestyles. Aspects of health behavior theory other than perceived risk need to be explored to help target efforts in the primary prevention of diabetes

Fully differential cross sections for photo-double-ionization of D2

We report the first kinematically complete study of the four-body fragmentation of the D2 molecule following absorption of a single photon. For equal energy sharing of the two electrons and a photon energy of 75.5 eV, we observed the relaxation of one of the selection rules valid for He photo-double-ionization and a strong dependence of the electron angular distribution on the orientation of the molecular axis. This effect is reproduced by a model in which a pair of photoionization amplitudes is introduced for the light polarization parallel and perpendicular to the molecular axis