Modeling Runoff and Sediment Yield in Highly Gullied Regions of Kashmir using SWAT Model: A Case Study of Lolab Watershed

Soil erosion in highly gullied regions of Kashmir valley is a serious global issue due to its impacts on economic productivity and environmental consequences such as land disintegration and one of the most affected areas is Lolab which is flood-prone and has witnessed several disastrous floods in the past. This means assessment of hydrological behavior should be highly prioritized and the most problematic sub-basins contributing to the erosion and excessive runoff identified to formulate and apply proper management strategies. This study integrated the Soil and Water Assessment Tool (SWAT) with Arc software to simulate the runoff and sediment yield of Lolab Watershed. The method was applied due to its flexibility in inputting data requirements and the capability to model larger catchments and mountainous areas. Meanwhile, sensitivity analysis showed the most sensitive four parameters for runoff estimation with the initial soil conservation service curve number II rated to be the highest and two others were found for sediment estimation with channel erodibility factor rated highest. The calibration of the values of these sensitive parameters led to the provision of reliable NashSutcliffe (NSE) and Coefficient of determination(R2) efficiencies which makes SWAT a good analyzing tool to assess the hydrological behavior of highly gullied region and un-gauged basins of Kashmir. These factors were found to be above 0.90 for both runoff and sediment yield and the sediment yield rates were estimated using SWAT at individual sub-basin levels after which a prioritization map was prepared to determine the most problematic sub-basins in the watershed.

SUPRA SOFT R-SEPARATION AXIOMS

This paper introduces the notion of supra soft b-separation axioms based on the supra b-open soft sets which are more general than supra open soft sets. We investigate the relationships between these supra soft separation axioms. Furthermore, with the help of examples it is established that the converse does not hol

Comparing the Effectiveness of Different Reinforcement Stimuli in a Robotic Therapy for Children With ASD

Recent research has shown reliability in robotic therapies for improvement in core impairments of autism. To improve the efficiency of communication using robots, this study evaluates the effectiveness of three different stimuli in a robotic intervention for children with autism spectrum disorder. Three different reinforcement stimuli presented in least-to-most (LTM) order introduced in this therapy using NAO robot are: visual (color variation), auditory and motion cues. The therapy was tested on 12 ASD children, 4 out of 12 children fall under mild category whereas 8 fall under the minimal category of autism. The experimentation was conducted for 2 months. Total 8 experiments were conducted with 1 trial per week. Total 12 cues were given per trial, 4 cues corresponding to each category. In total 96 cues were given per subject, 32 cues from each category. The results indicate a general trend for linking a particular autism category with the most effective stimulus for that category. It can be concluded that visual cue (color variation) is the most effective reinforcement stimulus for children with minimal autism as 8 out of 8 i.e., 100% were more responsive to visual cues whereas for children with mild autism category, 3 out of 4 i.e., 75% are more receptive towards the motion stimulus. The parameters used for assessment were joint attention and the time eye contact is maintained. Single factor ANOVA was used for the statistical analysis of results with alpha is 0.05 and p-value 0.0342, F value is 3.7456 and F critical value is 3.2834. The test was performed on 96 ( $8\times 12$ ) trails in total, therefore ensuring the significance and reliability of our results

Transition in Tuber Quality Attributes of Potato (Solanum tuberosum L.) Under Different Packaging Systems During Storage

The suitability of different packaging materials i.e. jute, nylon, polypropylene, cotton, low density polyethylene, medium density polyethylene, and high density polyethylene were studied for tubers of the premium potato (Solanum tuberosum L.) variety “Lady Rosetta”. After harvest, potato tubers were washed, sorted, graded, cured, and subsequently stored in different packaging materials at ambient temperature (25±2 °C). Changes in quality attributes of potato tubers under different packaging materials were studied on the basis of their physico-chemical and functional parameters. Overall results revealed that packaging materials had a significant (p ≤ 0.05) effect on many important quality attributes. Generally, weight loss, glucose and glycoalkaloid amounts, and polyphenol oxidase and peroxidase activities increased, while ascorbic acid contents decreased with increasing storage time. Total phenolic contents and radical scavenging activity showed a nearly parabolic trend during the storage period. Amongst the different packaging materials employed, potatoes stored in polypropylene and low-density polyethylene presented the best overall retention of vital quality attributes during 63 days storage. However, the higher tensile strength of polypropylene packaging made it a more durable and thus more effective material for prolonged potato tuber storage, a characteristic having clear advantages when used in typical marketing supply chains

An Experimental Trial: Multi-Robot Therapy for Categorization of Autism Level Using Hidden Markov Model

Several robot-mediated therapies have been implemented for diagnosis and improvement of communication skills in children with Autism Spectrum Disorder. The proposed research uses an existing model i.e., Multi-robot-mediated Intervention System (MRIS) in combination with Hidden Markov Model (HMM) to develop an infrastructure for categorizing the severity of autism in children. The observable states are joint attention type (low, delayed, and immediate) and imitation type (partial, moderate, and full) whereas the non-observable states are (level of autism i.e., (minimal, and mild). The research has been conducted on 12 subjects in which 8 children were in the training session with 72 experiments over 9 weeks, and the remaining 4 subjects were in the prediction test with 25 experiments for 6 weeks. The predicted category was compared with the actual category of autism assessed by the therapist using Childhood Autism Rating Scale. The accuracy of the proposed model is 76%. Further, a statistically significantly moderate Kappa measure of agreement between Childhood Autism Rating Scale and our proposed model has been performed in which n = 25, k = 0.52, and p = 0.009. This research contributes towards the usefulness of Hidden Markov Model integrated with joint attention and imitation modules for categorizing the level of autism using multi-robot therapies

Drug overdose: a wake up call! Experience at a tertiary care centre in Karachi, Pakistan

OBJECTIVE: To study the characteristics of patients admitted with drug overdose caused either by accidental overdose of the prescribed medications or as an act of deliberate self harm (DSH) at a tertiary care hospital in Karachi, Pakistan.METHODS: A retrospective case series review was conducted at the Aga Khan University Hospital from January 2002 to October 2006. Three hundred and twenty four adult patients admitted with drug overdose were included in the study.RESULTS: Our sample group revealed mean age of 36.2 +/- 17.0 years, more females (59%), housewives (34%), and students (20%). Fifty six percent of patients committing DSH were married (p = 0.001), 81% needed in-patient psychiatric services (p = 0.016) of whom a significantly high number (38%) refused it. Domestic and social issues were rated highest among DSH group (p = 0.003), depression among females was common (p = 0.028) and Benzodiazepines (41%) was the most frequently used drug (p = 0.021). Sub-group analysis of accidental overdoses revealed mean age of 45.6 +/- 19.6 years, single (75.4%) and males (54.1%). Drugs used were mainly Benzodiazepines (18%) followed by Opioids (11%), Antiepileptics (10%) and Warfarin (10%).CONCLUSION: Our study showed that depressed housewives are at greater risk for DSH. Domestic and social issues were rated highest and Benzodiazepines were the most commonly used agents. Most of our patients refused inpatient psychiatric treatment leading us to believe that general awareness of psychiatric illnesses is imperative in our community. High number of accidental overdoses is alarming in older, single males convincing us to believe that existing pharmacy system needs further evaluation and modification

Career goals of trainee physicians in internal medicine

OBJECTIVE: To survey Internal Medicine trainees\u27 future career choices and factors influencing their decision-making. DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: The Aga Khan University Hospital, Karachi, from November 2006 to January 2007. SUBJECTS AND METHODS: A standard questionnaire was administered to the residents and Interns working in the Department of Internal Medicine of The Aga Khan University Hospital. The questionnaire covered demographic details, specialty choice, work-time distribution and factors influencing career choice. Descriptive statistics were applied. RESULTS: A total of 49 doctors participated with 57% females; and 43% males, having 33% interns and 67% residents. A minority (22%) opted for internal medicine, while 78% selected sub-specialties with cardiology (20%) being the most sought- after sub-specialty. Majority (69%) wanted to spend more time in clinical activities compared to administration (18%) or research (13%). Majority (92%) wanted to work in an academic setting. Availability of a structured training program (61%), ability to practice broad area of medicine (41%) and prestige of the specialty (41%) highly influenced their career choices. Forty one (82%) wanted to proceed abroad for further training and 80% wanted to eventually practice in Pakistan. CONCLUSION: Most of the interviewed under-training physicians wanted to pursue sub-specialty. Clinical work was more attractive compared to research. A structured training program was detrimental in affecting their choices. Majority wanted further training abroad but eventual settlement in Pakistan. The study results can help us create the basis for reforming the current training programs

Distribution of Selenium in Soils and Human Health

Selenium (Se) is essential as well as a toxic element for humans and animals if it exceeds a certain limit. Soil selenium plays an important role through the food chain. Total selenium in world soils ranges from 0.125 to 0.3 mg kg−1 and varies with the soils’ nature. High and low selenium in soils also poses serious environmental and health risks. However, in addition to selenium\u27s overall quantity in soil, selenium reactivity, and bioavailability also depend on its chemical structure. The amount of available selenium in the soil varies depending on its oxidation state since selenium species include selenide (Se2−), elemental selenium (Se0), selenite (Seo32−), selenate (Seo42−). The pH, soil texture, amount of organic matter, and the presence of competing ions are the four most significant soil characteristics that affect Se availability. Similarly, selenium uptake and accumulation are influenced by the crop type whether it is an accumulator or not. The selenium environmental and health risk assessment is necessary to evaluate in soils with high selenium contents and crops with higher selenium uptake. Whereas in areas where selenium deficiency is observed or vulnerable to selenium, deficiency needs to be supplemented through Se inputs. The selenium deficiency and toxicity areas should be monitored carefully from a health perspective

Efficacy and safety of quinine loading dose in patients with severe falciparum malaria at a tertiary care hospital in Pakistan

OBJECTIVE: To compare the clinical outcomes of a loading dose regimen of quinine with a uniform dose regimen in patients with severe falciparum malaria. METHODS: A retrospective chart review of 315 patients admitted with severe falciparum malaria and treated with quinine at a tertiary care teaching hospital of Karachi, Pakistan during 1999-2006 was conducted. Group A with 103 patients (32.7%) was given an initial loading dose of quinine while group B with 212 patients (67.3%) did not receive the loading dose. The two groups were compared in terms of reduction of parasite load, resolution of fever, recovery of consciousness and incidence of adverse effects. Outcome parameters were measured on the third day of therapy. RESULTS: More individuals in group A (62.1%) were afebrile as compared to group B (54.7%) at day 3 of therapy. Patients in group B showed greater reduction in parasitaemia (47.2% at baseline to 4.7% on day 3) as compared to group A (56.3 % at baseline to 9.7% on day 3). Following therapy, fewer patients in group B had altered consciousness (7.1% at baseline to 4.7% on day 3) as compared to patients in group A (7.8% at baseline to 5.8% on day 3). However, these associations were not statistically significant. The incidence of thrombocytopenia was higher in Group A (5.8%) as compared to Group B (0.9%). CONCLUSION: Although quinine loading dose may be more effective than uniform dose in rapid fever clearance; it also appears to be associated with higher toxicity. Uniform dose of quinine may be prescribed in severe falciparum malaria in view of its better safety profile