The Tenth District's defining industries: changes and opportunities for rural communities

Rural areas ; Rural development ; Federal Reserve District, 10th

The national defense boost in rural America

Rural areas ; Rural development ; Defense contracts

Booms and busts in household wealth: implications for Tenth District states

The U.S. stock market and housing market--the two largest sources of U.S. household wealth--have had sizable booms and busts in recent years. This volatility has influenced national consumption trends and had important consequences for states. Some states have become relatively wealthier, affecting both the short- and long-term consumption spending potential of their residents. ; Understanding how wealth changes affect state economies could be especially important in 2011 and 2012 given the recent resumption of home price declines in much of the country. Research has shown that consumption can be more sensitive to changes in housing wealth than other types of wealth. While the home price collapse in 2007-09 hurt the Tenth District less than the nation, home price fundamentals in several District states may be more similar to the nation over the next couple of years. ; Wilkerson and Williams examine recent changes in household wealth in Tenth District states and explore how the region is positioned heading forward.

Minorities in the Tenth District: are they ready for the jobs of the future?

Employment ; Minorities - Employment ; Federal Reserve District, 10th

The Tenth District's defining industries: how are they changing?

The economy of the Tenth Federal Reserve District has become increasingly more services-based in recent years. While this transformation has lessened many of the historical differences with the rest of the nation, the regional economy still remains distinct, especially in some states. Wyoming, for instance, still has the most unique industrial structure in the country. And Nebraska, New Mexico, and Oklahoma still rank among the top third of states with economies that differ from the rest of the nation. ; What industries make the Tenth District so different, and what can they tell us about the future of the regional economy? ; Wilkerson and Williams examine the “defining” industries of the region. They find that the performance of a relatively small group of these industries track closely with overall job growth in each state. In other words, states whose defining industries have prospered in recent years have grown quickly overall, while states whose defining industries have struggled have grown sluggishly. Thus, identifying a state’s defining industries and understanding how they are changing can provide vital context for policymakers seeking to improve prospects for growth—as well as help identify the types of economic shocks that might threaten the region in the future.Federal Reserve District, 10th

The export potential of Tenth District states

After collapsing during the financial and economic crisis, exports have grown rapidly in the nation and across much of the Tenth Federal Reserve District. Despite some risks, most economic forecasts for national exports point to continued robust growth. An export boom, however, could have disparate effects across the country, given sizable differences in the volume, composition, and trends of state exports. ; Wilkerson and Williams assess the export potential of the Tenth District. They find that future export growth in the district is likely to be strong, although most states are likely to benefit less from the expected boom than the nation as a whole. Most states in the district have smaller export sectors than the nation and slightly less favorable export industry mixes. There are exceptions, though, and most district states have an adequate mix of trading partners. And, as in the past, other factors will play a role in the district’s export potential.

Mutational Analysis of the Rotavirus NSP4 Enterotoxic Domain that Binds to Caveolin-1

Background: Rotavirus (RV) nonstructural protein 4 (NSP4) is the first described viral enterotoxin, which induces early secretory diarrhea in neonatal rodents. Our previous data show a direct interaction between RV NSP4 and the structural protein of caveolae, caveolin-1 (cav-1), in yeast and mammalian cells. The binding site of cav-1 mapped to the NSP4 amphipathic helix, and led us to examine which helical face was responsible for the interaction. Methods: A panel of NSP4 mutants were prepared and tested for binding to cav-1 by yeast two hybrid and direct binding assays. The charged residues of the NSP4 amphipathic helix were changed to alanine (NSP446-175-ala6); and three residues in the hydrophobic face were altered to charged amino acids (NSP446-175-HydroMut). In total, twelve mutants of NSP4 were generated to define the cav-1 binding site. Synthetic peptides corresponding to the hydrophobic and charged faces of NSP4 were examined for structural changes by circular dichroism (CD) and diarrhea induction by a neonatal mouse study. Results: Mutations of the hydrophilic face (NSP446-175-Ala6) bound cav-1 akin to wild type NSP4. In contrast, disruption of the hydrophobic face (NSP446-175-HydroMut) failed to bind cav-1. These data suggest NSP4 and cav-1 associate via a hydrophobic interaction. Analyses of mutant synthetic peptides in which the hydrophobic residues in the enterotoxic domain of NSP4 were altered suggested a critical hydrophobic residue. Both NSP4HydroMut112-140, that contains three charged amino acids (aa113, 124, 131) changed from the original hydrophobic residues and NSP4AlaAcidic112-140 that contained three alanine residues substituted for negatively charged (aa114, 125, 132) amino acids failed to induce diarrhea. Whereas peptides NSP4wild type 112 −140 and NSP4AlaBasic112-140 that contained three alanine substituted for positively charged (aa115, 119, 133) amino acids, induced diarrhea. Conclusions: These data show that the cav-1 binding domain is within the hydrophobic face of the NSP4 amphipathic helix. The integrity of the helical structure is important for both cav-1 binding and diarrhea induction implying a connection between NSP4 functional and binding activities

Instream wood increases riverbed temperature variability in a lowland sandy stream

The (re)introduction of wood into rivers is becoming increasingly popular in river restoration and natural flood management schemes. While instream wood is known to promote geomorphic and hydraulic diversity, the impact of wood in driving surface water‐streambed exchange and subsequent streambed temperatures remains under‐researched, particularly in lowland rivers. We make use of the occurrence of three naturally occurring wood structures in a small, lowland sandy stream to determine how the presence of wood alters the geomorphic, hydraulic and thermal properties of the streambed. Our results show that instream wood plays an important role in promoting localized geomorphic complexity and thermal variation in the streambed. Locations within and immediately downstream of wood structures displayed the highest temperature range and daily variation. Locations upstream of wood structures were characterized by weaker daily temperature variation, while areas without wood displayed relatively stable streambed temperatures, with little diurnal fluctuation. Our study indicates that at this lowland site, instream wood increased seasonal temperature extremes (increased summer and decreased winter temperatures) at shallow depths by enhancing infiltration of warmer (summer) and colder (winter) surface water. This reduction in thermal buffering is likely to have significant implications to streambed‐dwelling communities and highlights that the thermal impacts of wood reintroduction in lowland rivers should be considered prior to river restoration

A High-Resolution Radio Continuum Study Of The Dwarf Irregular Galaxy IC 10

We present high-resolution e–MERLIN radio continuum maps of the Dwarf Irregular galaxy IC 10 at 1.5 GHz and 5 GHz. We detect 11 compact sources at 1.5 GHz, 5 of which have complementary detections at 5 GHz. We classify 3 extended sources as compact HII regions within IC 10, 5 sources as contaminating background galaxies and identify 3 sources which require additional observa- tions to classify. We do not expect that any of these 3 sources are Supernova Remnants as they will likely be resolved out at the assumed distance of IC 10 (0.7 Mpc). We correct integrated flux densities of IC 10 from the literature for contamination by unrelated background sources and ob- tain updated flux density measurements of 354 ± 11 mJy at 1.5 GHz and 199 ± 9 mJy at 4.85 GHz. The background contamination does not contribute significantly to the overall radio emission from IC 10, so previous analysis concerning its integrated radio properties remain valid