GAELS Project Final Report: Information environment for engineering

The GAELS project was a collaboration commenced in 1999 between Glasgow University Library and Strathclyde University Library with two main aims:· to develop collaborative information services in support of engineering research at the Universities of Glasgow and Strathclyde· to develop a CAL (computer-aided learning package) package in advanced information skills for engineering research students and staff The project was funded by the Scottish Higher Education Funding Council (SHEFC) from their Strategic Change Initiative funding stream, and funding was awarded initially for one year, with an extension of the grant for a further year. The project ended in June 2001.The funding from SHEFC paid for two research assistants, one based at Glasgow University Library working on collaborative information services and one based at Strathclyde University Library developing courseware. Latterly, after these two research assistants left to take up other posts, there has been a single researcher based at Glasgow University Library.The project was funded to investigate the feasibility of new services to the Engineering Faculties at both Universities, with a view to making recommendations for service provision that can be developed for other subject areas

Measuring children and young people's wellbeing in the school context

Although being rooted in the work of ancient Greek philosophers, contemporary research on wellbeing is a relatively new phenomenon. As a term in the literature, wellbeing is often used interchangeably with others, such as happiness, flourishing, enjoying a good life, and life satisfaction. Furthermore the wellbeing of school-aged children is only beginning to be explored with increasing recognition that research conducted on adults cannot be uncritically applied to children and young people. This paper aims to address some of the complexities in conceptualising, and hence assessing, children and young people’s wellbeing by drawing on a recently completed study examining the role of creative initiatives in fostering wellbeing. The new instrument that was developed to capture children and young people’s perceptions of their wellbeing in school is outlined. Data are presented from a survey of 5170 students from 20 primary and 20 secondary schools across England that identify four dimensions of wellbeing. Differences in self-reported wellbeing relating to age, gender and type of school attended (Creative Partnerships versus other schools) are explored. The implications of these findings, particularly differences related to type of school attended given the focus of this special edition, are considered.This is the author accepted manuscript. The final version is available from Taylor & Francis via http://dx.doi.org/10.1080/0305764X.2014.88965

Induction of Colonic Aberrant Crypts in Mice by Feeding Apparent N-Nitroso Compounds Derived From Hot Dogs

Nitrite-preserved meats (e.g., hot dogs) may help cause colon cancer because they contain N-nitroso compounds. We tested whether purified hot-dog-derived total apparent N-nitroso compounds (ANC) could induce colonic aberrant crypts, which are putative precursors of colon cancer. We purified ANC precursors in hot dogs and nitrosated them to produce ANC. In preliminary tests, CF1 mice received 1 or 3 i.p. injections of 5mg azoxymethane (AOM)/kg. In Experiments 1 and 2, female A/J mice received ANC in diet. In Experiment 1, ANC dose initially dropped sharply because the ANC precursors had mostly decomposed but, later in Experiment 1 and throughout Experiment 2, ANC remained at 85 nmol/g diet. Mice were killed after 8 (AOM tests) or 17–34 (ANC tests) wk.Median numbers of aberrant crypts in the distal 2 cm of the colon for 1 and 3 AOMinjections, CF1 controls, ANC (Experiment 1), ANC (Experiment 2),and untreated A/J mice were 31, 74, 12, 20, 12, and 5–6, with P < 0.01 for both ANC tests. Experiment 2 showed somewhat increased numbers of colonic mucin-depleted foci in the ANC-treated group. We conclude that hot-dog-derived ANC induced significant numbers of aberrant crypts in the mouse colon

Human infectivity trait in <i>Trypanosoma brucei</i>: stability, heritability and relationship to sra expression

Some Trypanosoma brucei lines infect humans whereas others do not because the parasites are lysed by human serum. We have developed a robust, quantitative in vitro assay based on differential uptake of fluorescent dyes by live and dead trypanosomes to quantify the extent and kinetics of killing by human serum. This method has been used to discriminate between 3 classes of human serum resistance; sensitive, resistant and intermediate. TREU 927/4, the parasite used for the T. brucei genome project, is intermediate. The phenotype is expressed in both bloodstream and metacyclic forms, is stably expressed during chromic infections and on cyclical transmission through tsetse flies. Trypanosomes of intermediate phenotype are distinguished from sensitive populations of cells by the slower rate of lysis and by the potential to become fully resistant to killing by human serum as a result of selection or long-term serial passaging in mice, and to pass on full resistance phenotype to its progeny in a genetic cross. The sra gene has been shown previously to determine human serum resistance in T. brucei but screening for the presence and expression of this gene indicated that it is not responsible for the human serum resistance phenotype in the trypanosome lines that we have examined, indicating that an alternative mechanism for HSR exists in these stocks. Examination of the inheritance of the phenotype in F1 hybrids for both bloodstream and metacyclic stages from 2 genetic crosses demonstrated that the phenotype is co-inherited in both life-cycle stages in a manner consistent with being a Mendelian trait, determined by only one or a few genes

The Pink Lady : Valse

https://digitalcommons.library.umaine.edu/mmb-ps/2115/thumbnail.jp

Here Comes Tootsi

https://digitalcommons.library.umaine.edu/mmb-vp/1452/thumbnail.jp

By the Saskatchewan

https://digitalcommons.library.umaine.edu/mmb-vp/4166/thumbnail.jp

Around The Map

https://digitalcommons.library.umaine.edu/mmb-ps/1370/thumbnail.jp