6,078 research outputs found
Splitting Proofs for Interpolation
We study interpolant extraction from local first-order refutations. We
present a new theoretical perspective on interpolation based on clearly
separating the condition on logical strength of the formula from the
requirement on the com- mon signature. This allows us to highlight the space of
all interpolants that can be extracted from a refutation as a space of simple
choices on how to split the refuta- tion into two parts. We use this new
insight to develop an algorithm for extracting interpolants which are linear in
the size of the input refutation and can be further optimized using metrics
such as number of non-logical symbols or quantifiers. We implemented the new
algorithm in first-order theorem prover VAMPIRE and evaluated it on a large
number of examples coming from the first-order proving community. Our
experiments give practical evidence that our work improves the state-of-the-art
in first-order interpolation.Comment: 26th Conference on Automated Deduction, 201
The lifecycle of axisymmetric internal solitary waves
The generation and evolution of solitary waves by intrusive gravity currents in an approximate two-layer fluid with equal upper- and lower-layer depths is examined in a cylindrical geometry by way of theory and numerical simulations. The study is limited to vertically symmetric cases in which the density of the intruding fluid is equal to the average density of the ambient. We show that even though the head height of the intrusion decreases, it propagates at a constant speed well beyond 3 lock radii. This is because the strong stratification at the interface supports the formation of a mode-2 solitary wave that surrounds the intrusion head and carries it outwards at a constant speed. The wave and intrusion propagate faster than a linear long wave; therefore, there is strong supporting evidence that the wave is indeed nonlinear. Rectilinear Korteweg-de Vries theory is extended to allow the wave amplitude to decay as <i>r<sup>-p</sup></I> with <i>p</i>=&frac12; and the theory is compared to the observed waves to demonstrate that the width of the wave scales with its amplitude. After propagating beyond 7 lock radii the intrusion runs out of fluid. Thereafter, the wave continues to spread radially at a constant speed, however, the amplitude decreases sufficiently so that linear dispersion dominates and the amplitude decays with distance as <i>r</i><sup>-1</sup>
From model system to clinical medicine: pathophysiologic links of common proteinopathies
Recent clinical evidence suggests that Alzheimer disease (AD), Parkinson disease (PD), and dementia with Lewy bodies (DLB), though distinct neurological disorders, have some common pathological features that may have an impact on the clinical characteristics of these diseases. However, the question of whether these disorders have a common pathophysiology remains. Clinton and colleagues recently reported a mouse model that exhibits the combined pathologies of AD, PD, and DLB, a finding that may shed some light on this issue. Using this mouse model, the authors demonstrate that the pathogenic proteins amyloid beta, tau, and alpha-synuclein interact synergistically to enhance the accumulation of one another and accelerate cognitive decline. These data indicate shared pathogenic mechanisms and suggest the possibility that therapeutic interventions successfully targeting one of these pathogenic proteins have implications for a number of related neurodegenerative disorders
Anatomy and Physiology of Artificial Intelligence in PET Imaging
The influence of artificial intelligence (AI) within the field of nuclear
medicine has been rapidly growing. Many researchers and clinicians are seeking
to apply AI within PET, and clinicians will soon find themselves engaging with
AI-based applications all along the chain of molecular imaging, from image
reconstruction to enhanced reporting. This expanding presence of AI in PET
imaging will result in greater demand for educational resources for those
unfamiliar with AI. The objective of this article to is provide an illustrated
guide to the core principles of modern AI, with specific focus on aspects that
are most likely to be encountered in PET imaging. We describe convolutional
neural networks, algorithm training, and explain the components of the commonly
used U-Net for segmentation and image synthesis
Tunneling spectra of strongly coupled superconductors: Role of dimensionality
We investigate numerically the signatures of collective modes in the
tunneling spectra of superconductors. The larger strength of the signatures
observed in the high-Tc superconductors, as compared to classical low-Tc
materials, is explained by the low dimensionality of these layered compounds.
We also show that the strong-coupling structures are dips (zeros in the d2I/dV2
spectrum) in d-wave superconductors, rather than the steps (peaks in d2I/dV2)
observed in classical s-wave superconductors. Finally we question the
usefulness of effective density of states models for the analysis of tunneling
data in d-wave superconductors.Comment: 8 pages, 6 figure
Properties of the superconducting state in a two-band model
Eliashberg theory is used to investigate the range of thermodynamic
properties possible within a two-band model for s-wave superconductivity and to
identify signatures of its two-band nature. We emphasize dimensionless BCS
ratios (those for the energy gaps, the specific heat jump and the negative of
its slope near Tc, the thermodynamic critical field Hc(0), and the normalized
slopes of the critical field and the penetration depth near Tc), which are no
longer universal even in weak coupling. We also give results for
temperature-dependent quantities, such as the penetration depth and the energy
gap. Results are presented both for microscopic parameters appropriate to MgB2
and for variations away from these. Strong coupling corrections are identified
and found to be significant. Analytic formulas are provided which show the role
played by the anisotropy in coupling in some special limits. Particular
emphasis is placed on small interband coupling and on the opposite limit of no
diagonal coupling. The effect of impurity scattering is considered,
particularly for the interband case.Comment: 20 pages, 14 figures, final version accepted in PR
Experimentally exploring compressed sensing quantum tomography
In the light of the progress in quantum technologies, the task of verifying
the correct functioning of processes and obtaining accurate tomographic
information about quantum states becomes increasingly important. Compressed
sensing, a machinery derived from the theory of signal processing, has emerged
as a feasible tool to perform robust and significantly more resource-economical
quantum state tomography for intermediate-sized quantum systems. In this work,
we provide a comprehensive analysis of compressed sensing tomography in the
regime in which tomographically complete data is available with reliable
statistics from experimental observations of a multi-mode photonic
architecture. Due to the fact that the data is known with high statistical
significance, we are in a position to systematically explore the quality of
reconstruction depending on the number of employed measurement settings,
randomly selected from the complete set of data, and on different model
assumptions. We present and test a complete prescription to perform efficient
compressed sensing and are able to reliably use notions of model selection and
cross-validation to account for experimental imperfections and finite counting
statistics. Thus, we establish compressed sensing as an effective tool for
quantum state tomography, specifically suited for photonic systems.Comment: 12 pages, 5 figure
Numerical study of surface-induced reorientation and smectic layering in a nematic liquid crystal
Surface-induced profiles of both nematic and smectic order parameters in a
nematic liquid crystal, ranging from an orienting substrate to "infinity", were
evaluated numerically on base of an extended Landau theory. In order to obtain
a smooth behavior of the solutions at "infinity" a boundary energy functional
was derived by linearizing the Landau energy around its equilibrium solutions.
We find that the intrinsic wave number of the smectic structure, which plays
the role of a coupling between nematic and smectic order, strongly influences
the director reorientation. Whereas the smectic order is rapidly decaying when
moving away from the surface, the uniaxial nematic order parameter shows an
oscillatory behavior close to the substrate, accompanied by a non-zero local
biaxiality.Comment: LaTeX, 17 pages, with 4 postscript figure
Candidatus Bartonella merieuxii, a potential new zoonotic Bartonella species in canids from Iraq.
Bartonellae are emerging vector-borne pathogens infecting erythrocytes and endothelial cells of various domestic and wild mammals. Blood samples were collected from domestic and wild canids in Iraq under the United States Army zoonotic disease surveillance program. Serology was performed using an indirect immunofluorescent antibody test for B. henselae, B. clarridgeiae, B. vinsonii subsp. berkhoffii and B. bovis. Overall seroprevalence was 47.4% in dogs (n = 97), 40.4% in jackals (n = 57) and 12.8% in red foxes (n = 39). Bartonella species DNA was amplified from whole blood and representative strains were sequenced. DNA of a new Bartonella species similar to but distinct from B. bovis, was amplified from 37.1% of the dogs and 12.3% of the jackals. B. vinsonii subsp. berkhoffii was also amplified from one jackal and no Bartonella DNA was amplified from foxes. Adjusting for age, the odds of dogs being Bartonella PCR positive were 11.94 times higher than for wild canids (95% CI: 4.55-31.35), suggesting their role as reservoir for this new Bartonella species. This study reports on the prevalence of Bartonella species in domestic and wild canids of Iraq and provides the first detection of Bartonella in jackals. We propose Candidatus Bartonella merieuxii for this new Bartonella species. Most of the Bartonella species identified in sick dogs are also pathogenic for humans. Therefore, seroprevalence in Iraqi dog owners and bacteremia in Iraqi people with unexplained fever or culture negative endocarditis requires further investigation as well as in United States military personnel who were stationed in Iraq. Finally, it will also be essential to test any dog brought back from Iraq to the USA for presence of Bartonella bacteremia to prevent any accidental introduction of a new Bartonella species to the New World
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