Validation of the face-name pairs task in major depression: impaired recall but not recognition

Major depression can be associated with neurocognitive deficits which are believed in part to be related to medial temporal lobe pathology. The purpose of this study was to investigate this impairment using a hippocampal-dependent neuropsychological task. The face-name pairs task was used to assess associative memory functioning in 19 patients with major depression. When compared to age-sex-and-education matched controls, patients with depression showed impaired learning, delayed cued-recall, and delayed free-recall. However, they also showed preserved recognition of the verbal and nonverbal components of this task. Results indicate that the face-name pairs task is sensitive to neurocognitive deficits in major depression.Thisresearchwasfundedbya4-yearHealthResearch Board grant

Eliminating ambiguities for quantum corrections to strings moving in AdS4×CP3AdS_4\times \mathbb{CP}^3

We apply a physical principle, previously used to eliminate ambiguities in quantum corrections to the 2 dimensional kink, to the case of spinning strings moving in $AdS_4\times \mathbb{CP}^3$, thought of as another kind of two dimensional soliton. We find that this eliminates the ambiguities and selects the result compatible with AdS/CFT, providing a solid foundation for one of the previous calculations, which found agreement. The method can be applied to other classical string "solitons".Comment: 18 pages, latex; references added, comments added at end of section 4, a few words changed; footnote added on page 1

Kaluza-Klein gauge and minimal integrable extension of OSp(4|6)/(SO(1,3) x U(3)) sigma-model

Basing upon experience from performing double-dimensional reduction of the D=11 supermembrane on AdS_4 x S^7 background to Type IIA superstring on AdS_4 x CP^3 we introduce Kaluza-Klein (partial) kappa-symmetry gauge as a vanishing condition of the contribution to the D=11 supervielbein components tangent to D=10 space-time proportional to the differential of the coordinate parametrizing compact 11-th space-time dimension, that is identified with the supermembrane world-volume compact dimension. For AdS_4 x S^7 supermembrane Kaluza-Klein gauge removes half Grassmann coordinates associated with 8 space-time supersymmetries, broken by the AdS_4 x CP^3 superbackground, by imposing D=3 (anti-)Majorana condition on them. The consideration relies on the realization of osp(4|8) isometry superalgebra of the AdS_4 x S^7 superbackground as D=3 N=8 superconformal algebra. Requiring further vanishing of the D=10 dilaton leaves in the sector of broken supersymmetries just two Grassmann coordinates organized into D=3 (anti-)Majorana spinor that defines minimal SL(2,R)-covariant extension of the OSp(4|6)/(SO(1,3)x U(3)) sigma-model. Among 4 possibilities of such a minimal extension we consider in detail one, that corresponds to picking out D=3 Majorana coordinate related to broken Poincare supersymmetry, and show that the AdS_4 x CP^3 superstring equations of motion in this partial kappa-symmetry gauge are integrable. Also the relation between the OSp(4|6)/(SO(1,3) x U(3)) sigma-model and the AdS_4 x CP^3 superstring is revisited.Comment: LaTeX, 22 pages; v2: minor improvements in the text, typos corrected, references adde

EEG Source Imaging Indices of Cognitive Control Show Associations with Dopamine System Genes.

Cognitive or executive control is a critical mental ability, an important marker of mental illness, and among the most heritable of neurocognitive traits. Two candidate genes, catechol-O-methyltransferase (COMT) and DRD4, which both have a roles in the regulation of cortical dopamine, have been consistently associated with cognitive control. Here, we predicted that individuals with the COMT Met/Met allele would show improved response execution and inhibition as indexed by event-related potentials in a Go/NoGo task, while individuals with the DRD4 7-repeat allele would show impaired brain activity. We used independent component analysis (ICA) to separate brain source processes contributing to high-density EEG scalp signals recorded during the task. As expected, individuals with the DRD4 7-repeat polymorphism had reduced parietal P3 source and scalp responses to response (Go) compared to those without the 7-repeat. Contrary to our expectation, the COMT homozygous Met allele was associated with a smaller frontal P3 source and scalp response to response-inhibition (NoGo) stimuli, suggesting that while more dopamine in frontal cortical areas has advantages in some tasks, it may also compromise response inhibition function. An interaction effect emerged for P3 source responses to Go stimuli. These were reduced in those with both the 7-repeat DRD4 allele and either the COMT Val/Val or the Met/Met homozygous polymorphisms but not in those with the heterozygous Val/Met polymorphism. This epistatic interaction between DRD4 and COMT replicates findings that too little or too much dopamine impairs cognitive control. The anatomic and functional separated maximally independent cortical EEG sources proved more informative than scalp channel measures for genetic studies of brain function and thus better elucidate the complex mechanisms in psychiatric illness

QCD properties of twist operators in the N=6 Chern-Simons theory

We consider twist-1, 2 operators in planar N=6 superconformal Chern-Simons ABJM theory. We derive higher order anomalous dimensions from integrability and test various QCD-inspired predictions known to hold in N=4 SYM. In particular, we show that the asymptotic anomalous dimensions display intriguing remnants of Gribov-Lipatov reciprocity and Low-Burnett-Kroll logarithmic cancellations. Wrapping effects are also discussed and shown to be subleading at large spin.Comment: 22 pages, expanded reference

Versatile ytterbium ion trap experiment for operation of scalable ion-trap chips with motional heating and transition-frequency measurements

We present the design and operation of an ytterbium ion trap experiment with a setup offering versatile optical access and 90 electrical interconnects that can host advanced surface and multilayer ion trap chips mounted on chip carriers. We operate a macroscopic ion trap compatible with this chip carrier design and characterize its performance, demonstrating secular frequencies >1 MHz, and trap and cool nearly all of the stable isotopes, including 171Yb+ ions, as well as ion crystals. For this particular trap we measure the motional heating rate 〈ṅ〉 and observe an 〈ṅ〉∝1/ω2 behavior for different secular frequencies ω. We also determine a spectral noise density SE(1 MHz)=3.6(9)×10-11 V2 m-2 Hz-1 at an ion electrode spacing of 310(10) μm. We describe the experimental setup for trapping and cooling Yb+ ions and provide frequency measurements of the 2S1/2↔2P1/2 and 2D3/2↔3D[3/2]1/2 transitions for the stable 170Yb+, 171Yb+, 172Yb+, 174Yb+, and 176Yb+ isotopes which are more precise than previously published work

Trigger point manual therapy for the treatment of chronic non-cancer pain in adults

This is the protocol for a review and there is no abstract. The objectives are as follows: To determine the effectiveness of trigger point manual therapy for treating chronic non-cancer pain in adults

The AdS(4) x CP(3) string and its Bethe equations in the near plane wave limit

We perform a detailed study of bosonic type IIA string theory in a large light-cone momentum / near plane wave limit of $AdS_4 \times CP_3$. In order to attain this we derive the Hamiltonian up to cubic and quartic order in number of fields and calculate the energies for string excitations in a $R\times S^2 \times S^2$ subspace. The computation for the string energies is performed for arbitrary length excitations utilizing an unitary transformation which allows us to remove the cubic terms in the Hamiltonian. We then rewrite a recent set of proposed all loop Bethe equations in a light-cone language and compare their predictions with the obtained string energies. We find perfect agreement.Comment: 28 pages, references and footnote adde