24 research outputs found
Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion
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Decoration of an α-Resorcylate Nucleus as Part of the Manufacture of a Glucokinase Activator
No full textGlucokinase activators: molecular tools for studying the physiology of insulin-secreting cells
No full textUnexpected reactivity of two-coordinate palladium carbene complexes; synthetic and catalytic implications
No full textLigand exchange reactions reveal unexpected lability of the carbene ligands in two coordinate palladium(0) N-heterocyclic carbene complexes; the latter are found to be very effective catalysts for amination of aryl chlorides
Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats
No full textGlucose-Dependent Modulation of Insulin Secretion and Intracellular Calcium Ions by GKA50, a Glucokinase Activator
No full textQuinazolin-4-one derivatives lacking toxicity-producing attributes as glucokinase activators: design, synthesis, molecular docking, and in-silico ADMET prediction
No full textOptimisation of aqueous solubility in a series of G protein coupled receptor 119 (GPR119) agonists
No full textSolubility improvements in a series of GPR119 agonists are achieved through reduction of lipophilicity together with hydrogen bond acceptor modulation.</p
