60 research outputs found

    Cultural Resources Monitoring for the San Antonio Light and Print Building Project, San Antonio, Bexar County, Texas

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    Over eight days in May and August 2019, and May, June, July, and September 2020 the Center for Archaeological Research (CAR) at the University of Texas at San Antonio conducted archaeological monitoring in advance of the planned construction of a 3,000 square foot, five-story addition for the San Antonio Light and Print Building Project located in downtown San Antonio, Bexar County, Texas. CAR was contracted by GrayStreet Partners to monitor the mechanical excavation of seven holes for piers to support an elevated walkway and mechanical trenching for the installation of utilities and a 6.1 m emergency vehicular ingress and egress easement ramp leading to a future underground parking area. The project is privately funded and located on privately owned property between Broadway Street, McCullough Avenue, N. Alamo Street, and 4th Street in downtown San Antonio. As a result, the project was not subject to regulatory review by the Texas Historical Commission (THC). The project area is within the National Register of Historic Places (NRHP) San Antonio Downtown and River Walk Historic District, which adjoins three other NRHP Historic Districts: Alamo Plaza, Main and Military Plaza, and La Villita. The project is subject to regulatory review by the City of San Antonio (COSA) Office of Historic Preservation (OHP) under the COSA Unified Development Code (Article 6 35-630 to 35-634). Dr. Paul Shawn Marceaux, CAR Director, served as the Principal Investigator and managed the project until his departure from CAR, at which time Dr. Raymond Mauldin took over the Principal Investigator role. Jason Brian Perez served as the Project Archaeologist. The project area was 0.47 hectare (1.15 acres). CAR monitored the mechanical drilling of the first two pier holes, it was determined that the starting elevation was approximately 4.5 m below the original ground surface, in culturally sterile sediments. The drilling of the remaining five holes was not monitored. The initial trench excavation for the easement ramp was completed without notifying CAR. A nineteenth-century privy/trash pit feature was identified in the trench wall by CAR archaeologists, and diagnostic artifacts, dating from 1870-1900, were recovered from the backfill. The privy/trash pit feature was associated with the property owned by the Hagans family from 1859-1895, and it was designated as site 41BX2362. CAR recommends that site 41BX2362 is not eligible for NRHP or for listing as a State Antiquities Landmark (SAL). The CAR recommends no additional testing within the project area and that development proceed. In the event that additional construction reveals archaeological deposits, work should cease, and the City Archaeologist of the COSA-OHP should be notified. COSAOHP concurred with these recommendations. All recovered artifacts were offered to the landowner. Because the landowner failed to respond to several requests, CAR made the decision to curate selected diagnostic artifacts and discard the remainder. All collected artifacts are documented in the CAR’s collection management database. Selected diagnostic artifacts collected from the feature and all project documentation, including photographs, field forms, and a copy of this report were prepared for curation according to THC guidelines. The artifacts and records are permanently curated at the CAR repository as accession file 2266

    Investigations at the Vollrath Blacksmith Shop (41BX786), San Antonio, Bexar County, Texas

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    In May 1988, archival research was initiated to evaluate the archaeological potential of New City Block 102, Lots 10 through 15, in downtown San Antonio, Texas, proposed site of the new Bexar County Justice Center parking garage. The research indicated that the southern portion of Lots 10 and 11 would required further investigation at the 1874 site of Vollrath\u27s blacksmith shop. Field excavations were conducted in August 1988. This report discusses the archival research and the results of the field excavations

    Archaeological Investigations within San Pedro Springs Park (41BX19), San Antonio, Bexar County, Texas

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    The University of Texas at San Antonio Center for Archaeological Research (UTSA-CAR) contracted with Adams Environmental, Inc. to provide archaeological services to Capital Improvement Management (CIMS) of the City of San Antonio (COSA) related to the archaeological investigation of selected areas of San Pedro Springs Park in San Antonio, Bexar County, Texas. The CAR conducted archaeological testing at this National Register Site, 41BX19, from early December 2013 to mid-January of 2014. The goals of archaeological investigations were to identify and investigate any proto-historic and historic archaeological deposits associated with Colonial Period occupants of the area, including evidence of the first acequia and associated dam, and the location of the first presidio and villa. In addition, CAR was tasked with the investigation of any prehistoric cultural deposits encountered. This project was performed by staff archaeologists from the CAR. It was conducted under Texas Antiquities Permit No. 6727, with Dr. Steve Tomka serving as Principal Investigator (PI), and Kristi Nichols and Stephen Smith serving as Project Archaeologists. Dr. Tomka departed from UTSA shortly after the completion of fieldwork. At that time, Dr. Raymond Mauldin of CAR assumed PI responsibilities for the project. One hundred and eleven shovel tests, eleven 1-x-1 m test units, two 50-x-50 cm units, two backhoe trenches, and several auger holes were excavated during this effort. Minimal artifactual evidence of colonial occupants was noted during the archaeological investigations. Several Native American bone tempered sherds that could reflect either Late Prehistoric Leon Plain or Goliad ware were recovered. However, no Spanish Majolicas or lead glazed wares were uncovered, and no gunflints were identified in the lithic assemblage. Due to various utility lines and other obstructions, backhoe trenches to search for the acequia and associated dam could not be excavated. It is likely that areas proposed for investigation of the acequia and associated dam have been disturbed by aforementioned utility lines as well as earlier construction within the park. No evidence of the specific location of the first presidio or villa was located. Shovel testing and test units revealed the presence of historic and prehistoric use of the park, though mixing of historic and prehistoric material, as well as other disturbances (e.g., rodents), was common in the deposits. However, there was an increase in prehistoric material with depth as revealed in shovel testing results. Shovel testing located Feature 1, a burned rock feature that possibly was associated with a sheet midden, as well as several areas with high densities of prehistoric materials. Test excavations, based on these shovel tests, suggest that Feature 1 is a discrete feature that lies below a widespread, low-density distribution of burned rock. Shovel testing also identified a high-density cluster of lithic, bone, and burned rock. The excavation of a 1-x-1 m test unit (TU 4) in this area produced over 4,000 pieces of debitage, with over 50% of this total coming from three levels. Burned rock, a variety of tools, faunal material, and charcoal were present throughout these levels. Temporal placement of deposits relied on artifact typologies (e.g., ceramic types, lithic projectile points, lithic tool types) as well as two charcoal and four bone collagen radiocarbon dates. Artifact typologies suggest occupation as early as the Early Archaic as reflected by a possible Guadalupe tool. A series of Late Archaic Points (Castroville, Frio, Marcos, and Montell) and Late Prehistoric point forms (Edwards, Perdiz, and Scallorn) are present from several areas. In addition, a possible Middle Archaic La Jita point was recovered. The bone tempered Native American wares could date as early as AD 1250, though they could also reflect proto-historic or colonial age materials. Other ceramics primarily suggest a mid-nineteenth- to midtwentieth- century occupation. Using the midpoints of the 1-sigma distribution, calibrated radiocarbon dates show use of San Pedro Park from as early as 100 AD (CAR 345; 1905 +/- 22 Radiocarbon Years Before Present [RCYBP]) to as recently as the early twentieth century. The more recent end of that range is a function of two late dates from two different areas of the park. The first of these is on a bison bone (CAR 344) that returned a date of 158 +/- 23 RCYBP. The second is on a bone consistent with a bison-sized animal (CAR 346) that produced a date of 155 +/- 23 RCYBP. The corrected, calibrated dates for these two samples range from AD 1670 to the early 1940s using the 1-sigma spread. The wide range of these dates is related to the flat calibration curve late in time. However, the most probable date range (ca. 36% probability) for these two dates is between AD 1729 and 1779, with a roughly 48% probability that they date prior to AD 1779. Limited testing suggests that, with a few specific exceptions, the upper 30-40 cm of San Pedro Park is extensively disturbed. However, though some disturbances are present, at least three areas have materials in what appears to be good context. These include material dating to the Late Archaic, Late Prehistoric, and possibly the Proto-historic or Colonial Period. Based on historic maps, previous work, and the current investigation, CAR proposes a series of management areas for San Pedro Park. If work in these management areas follows these suggestions for various limits on subsurface impacts, CAR recommends that renovation activities within the park be allowed to proceed. The Texas Historical Commission (THC), in a letter dated February 4, 2015, agreed with these recommendations. Finally, CAR provides several recommendations for public education facilities within the park. In accordance with the THC Permit specifications and the Scope of Work for this project, all field notes, analytical notes, photographs, and other project related documents, along with a copy of the final report, will be curated at the CAR. After quantification and completion of analysis, and in consultation with THC and the COSA Office of Historic Preservation, artifacts possessing little scientific value were discarded pursuant to Chapter 26.27(g)(2) of the Antiquities Code of Texas. Artifact classes discarded specific to this project included samples of burned rock and snail shell, all unidentifiable metal, soil samples, and recent (post-1950) material

    L-arginase induces vascular dysfunction in old spontaneously hypertensive rats

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    Background: Aging is a major non-modifiable risk factor for hypertension. Changes in aging are similar to those seen in hypertension in the vasculature. Also, aging increases the vascular dysfunction that occurs in hypertension. L-arginase action reduces substrate (L-arginine) availability for the formation of nitric oxide (NO). This reduces the level of NO and leads to reduced vasodilation and ultimately, vascular dysfunction. This study examines the hypothesis that age-dependent vascular dysfunction in SHRs is mediated by arginase.Methods: Young (12-14 weeks) and old (11-12 months) male Wistar and spontaneously hypertensive rats (SHR) were used. Mean arterial pressure (MAP) was measured in the rats. They were then euthanized and mesenteric resistance arteries (MRAs) and thoracic aortae were excised and placed in ice-cold physiological salt solution (PSS). Arterial segments were either snap-frozen in liquid nitrogen and stored for immunoblotting studies or cut into 2mm rings for reactivity studies. Cumulative concentration-response curves to acetylcholine (Ach; 10-9 – 3x10-5M) and sodium nitroprusside (SNP; 10-12 – 3x10-5 M) were performed in the absence or presence (30-minute exposure) of L-arginase, 0.05U/ML (MRA) or 0.5U/ML (aorta). Vessels were pre-contracted with phenylephrine (PE; 3x10-6M)Results: MAP increased during aging in the SHRs p<0.05 but not in the Wistar rats. Arginase impaired the endothelium-dependent relaxation responses of thoracic aortic and MRA arterial rings to Ach in the old Wistars and SHRs (Emax aorta: 29.42±2.19% vs 7.94±1.86%). Arginase also impaired endothelium-independent relaxation response to SNP in the old SHRs only (Emax aorta: 88.62±4.10% vs 31.45±10.61%). We also observed no differences in the serum arginase activity in the four groups of rats. On the contrary, arginase activity in the aortae of young Wistar rats was reduced compared to other groups.Conclusions: Arginase impairs both endothelium-dependent and –independent vasorelaxation responses, through the NO signaling pathway.Keywords: Hypertension, Arginase, aging, vascular dysfunction, endothelium, Nitric oxid

    Archaeological Monitoring and Test Excavations at the 1722 Presidio San Antonio de Bexar (Plaza de Armas Buildings), San Antonio, Bexar County, Texas

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    From April 2013 to November 2014, the Center for Archaeological Research (CAR) at The University of Texas at San Antonio (UTSA) conducted archaeological monitoring and test excavations at the site of the 1722 Presidio San Antonio de Bexar, also known in the nineteenth and twentieth centuries as the Plaza de Armas Buildings (Vogel Belt Complex) within Military Plaza in San Antonio, Bexar County, Texas. The project was performed for Ford, Powell and Carson, Architects and Planners, Inc. under contract with the City of San Antonio in anticipation of renovations and improvements to the Plaza de Armas Buildings (Vogel Belt Complex) to serve as offices and studios for the City of San Antonio. The complex is listed as contributing to the Main and Military Plaza National Register of Historic Places District, with the buildings listed individually on the National Register of Historic Places (NRHP). In addition to the above, the property is owned by the City of San Antonio. Compliance with the Antiquities Code of Texas was required. As such, the State Antiquities Code and Chapter 35 of the San Antonio Local Government Code that require coordination with the City Office of Historic Preservation and the Texas Historical Commission Divisions of Archaeology and Architecture govern the undertakings. CAR, therefore, conducted the work under Texas Antiquities Committee Permit No. 6526. Dr. Steve A. Tomka served as the Principal Investigator for the majority of the fieldwork, the initial analysis, and the description of materials collected. Kristi Nichols served as the Project Archaeologist during this initial monitoring and testing, assisted by Lindy Martinez. Both Dr. Tomka and Ms. Nichols left UTSA in 2014, and Dr. Raymond Mauldin assumed the Principal Investigator role for the project. Clinton McKenzie and Leonard Kemp were the Project Archaeologists for the final phases of monitoring, as well as for assembling the final report. Leonard Kemp oversaw additional test excavation. Trinomial 41BX2088 was assigned to the location. Principal activities during the project included monitoring trenches on the complex’s exterior, monitoring soil removal in sections of the interior, and hand excavations of a series of units in the basement. These basement excavations produced a variety of materials. CAR staff documented eight features, including several trash pits, recovered a variety of Spanish Colonial, Native American, and European/English ceramics, along with faunal material, chipped stone tools and debitage, and construction related items. It was concluded that much of this material was intact, and that additional features and midden deposits are present. The project provides direct evidence of materials associated with the Presidio de Bexar, built by the Spanish at this general location in 1722, as well as occupation in this area through the early twentieth century. CAR recommends that prior to any impacts in the basements, or any external impacts greater than 2.0 m in depth at the rear of the Plaza de Armas Buildings (Vogel Belt Complex), a comprehensive, systematic effort to recover significant data be initiated

    Archaeological Investigations within San Pedro Springs Park (41BX19), San Antonio, Bexar County, Texas

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    The University of Texas at San Antonio Center for Archaeological Research (UTSA-CAR) contracted with Adams Environmental, Inc. to provide archaeological services to Capital Improvement Management (CIMS) of the City of San Antonio (COSA) related to the archaeological investigation of selected areas of San Pedro Springs Park in San Antonio, Bexar County, Texas. The CAR conducted archaeological testing at this National Register Site, 41BX19, from early December 2013 to mid-January of 2014. The goals of archaeological investigations were to identify and investigate any proto-historic and historic archaeological deposits associated with Colonial Period occupants of the area, including evidence of the first acequia and associated dam, and the location of the first presidio and villa. In addition, CAR was tasked with the investigation of any prehistoric cultural deposits encountered. This project was performed by staff archaeologists from the CAR. It was conducted under Texas Antiquities Permit No. 6727, with Dr. Steve Tomka serving as Principal Investigator (PI), and Kristi Nichols and Stephen Smith serving as Project Archaeologists. Dr. Tomka departed from UTSA shortly after the completion of fieldwork. At that time, Dr. Raymond Mauldin of CAR assumed PI responsibilities for the project. One hundred and eleven shovel tests, eleven 1-x-1 m test units, two 50-x-50 cm units, two backhoe trenches, and several auger holes were excavated during this effort. Minimal artifactual evidence of colonial occupants was noted during the archaeological investigations. Several Native American bone tempered sherds that could reflect either Late Prehistoric Leon Plain or Goliad ware were recovered. However, no Spanish Majolicas or lead glazed wares were uncovered, and no gunflints were identified in the lithic assemblage. Due to various utility lines and other obstructions, backhoe trenches to search for the acequia and associated dam could not be excavated. It is likely that areas proposed for investigation of the acequia and associated dam have been disturbed by aforementioned utility lines as well as earlier construction within the park. No evidence of the specific location of the first presidio or villa was located. Shovel testing and test units revealed the presence of historic and prehistoric use of the park, though mixing of historic and prehistoric material, as well as other disturbances (e.g., rodents), was common in the deposits. However, there was an increase in prehistoric material with depth as revealed in shovel testing results. Shovel testing located Feature 1, a burned rock feature that possibly was associated with a sheet midden, as well as several areas with high densities of prehistoric materials. Test excavations, based on these shovel tests, suggest that Feature 1 is a discrete feature that lies below a widespread, low-density distribution of burned rock. Shovel testing also identified a high-density cluster of lithic, bone, and burned rock. The excavation of a 1-x-1 m test unit (TU 4) in this area produced over 4,000 pieces of debitage, with over 50% of this total coming from three levels. Burned rock, a variety of tools, faunal material, and charcoal were present throughout these levels. Temporal placement of deposits relied on artifact typologies (e.g., ceramic types, lithic projectile points, lithic tool types) as well as two charcoal and four bone collagen radiocarbon dates. Artifact typologies suggest occupation as early as the Early Archaic as reflected by a possible Guadalupe tool. A series of Late Archaic Points (Castroville, Frio, Marcos, and Montell) and Late Prehistoric point forms (Edwards, Perdiz, and Scallorn) are present from several areas. In addition, a possible Middle Archaic La Jita point was recovered. The bone tempered Native American wares could date as early as AD 1250, though they could also reflect proto-historic or colonial age materials. Other ceramics primarily suggest a mid-nineteenth- to midtwentieth-century occupation. Using the midpoints of the 1-sigma distribution, calibrated radiocarbon dates show use of San Pedro Park from as early as 100 AD (CAR 345; 1905 +/- 22 Radiocarbon Years Before Present [RCYBP]) to as recently as the early twentieth century. The more recent end of that range is a function of two late dates from two different areas of the park. The first of these is on a bison bone (CAR 344) that returned a date of 158 +/- 23 RCYBP. The second is on a bone consistent with a bison-sized animal (CAR 346) that produced a date of 155 +/- 23 RCYBP. The corrected, calibrated dates for these two samples range from AD 1670 to the early 1940s using the 1-sigma spread. The wide range of these dates is related to the flat calibration curve late in time. However, the most probable date range (ca. 36% probability) for these two dates is between AD 1729 and 1779, with a roughly 48% probability that they date prior to AD 1779. Limited testing suggests that, with a few specific exceptions, the upper 30-40 cm of San Pedro Park is extensively disturbed. However, though some disturbances are present, at least three areas have materials in what appears to be good context. These include material dating to the Late Archaic, Late Prehistoric, and possibly the Proto-historic or Colonial Period. Based on historic maps, previous work, and the current investigation, CAR proposes a series of management areas for San Pedro Park. If work in these management areas follows these suggestions for various limits on subsurface impacts, CAR recommends that. renovation activities within the park be allowed to proceed. The Texas Historical Commission (THC), in a letter dated February 4, 2015, agreed with these recommendations. Finally, CAR provides several recommendations for public education facilities within the park. In accordance with the THC Permit specifications and the Scope of Work for this project, all field notes, analytical notes, photographs, and other project related documents, along with a copy of the final report, will be curated at the CAR. After quantification and completion of analysis, and in consultation with THC and the COSA Office of Historic Preservation, artifacts possessing little scientific value were discarded pursuant to Chapter 26.27(g)(2) of the Antiquities Code of Texas. Artifact classes discarded specific to this project included samples of burned rock and snail shell, all unidentifiable metal, soil samples, and recent (post-1950) material

    An Adaptive Decision Framework for the Conservation of a Threatened Plant

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    This is the publisher's version, also available electronically from http://www.fwspubs.org/.Mead's milkweed Asclepias meadii, a long-lived perennial herb of tallgrass prairie and glade communities of the central United States, is a species designated as threatened under the U.S. Endangered Species Act. Challenges to its successful management include the facts that much about its life history is unknown, its age at reproductive maturity is very advanced, certain life stages are practically unobservable, its productivity is responsive to unpredictable environmental events, and most of the known populations occur on private lands unprotected by any legal conservation instrument. One critical source of biological uncertainty is the degree to which fire promotes growth and reproductive response in the plant. To aid in its management, we developed a prototype population-level state-dependent decision-making framework that explicitly accounts for this uncertainty and for uncertainties related to stochastic environmental effects and vital rates. To parameterize the decision model, we used estimates found in the literature, and we analyzed data from a long-term monitoring program where fates of individual plants were observed through time. We demonstrate that different optimal courses of action are followed according to how one believes that fire influences reproductive response, and we show that the action taken for certain population states is informative for resolving uncertainty about competing beliefs regarding the effect of fire. We advocate the use of a model-predictive approach for the management of rare populations, particularly when management uncertainty is profound. Over time, an adaptive management approach should reduce uncertainty and improve management performance as predictions of management outcome generated under competing models are continually informed and updated by monitoring data

    Urothelial Senescence in the Pathophysiology of Diabetic Bladder Dysfunction—A Novel Hypothesis

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    Diabetic bladder dysfunction (DBD) is a well-recognized and common symptom affecting up to 50% of all diabetic patients. DBD has a broad range of clinical presentations ranging from overactive to underactive bladder symptoms that develops in middle-aged to elderly patients with long standing and poorly controlled diabetes. Low efficacy of current therapeutics and lifestyle interventions combined with high national healthcare costs highlight the need for more research into bladder dysfunction pathophysiology and novel treatment options. Cellular senescence is an age-related physiologic process in which cells undergo irreversible growth arrest induced by replicative exhaustion and damaging insults. While controlled senescence negatively regulates cell proliferation and promotes tissue regeneration, uncontrolled senescence is known to result in tissue dysfunction through enhanced secretion of inflammatory factors. This review presents previous scientific findings and current hypotheses that characterize diabetic bladder dysfunction. Further, we propose the novel hypothesis that cellular senescence within the urothelial layer of the bladder contributes to the pro-inflammatory/pro-oxidant environment and symptoms of diabetic bladder dysfunction. Our results show increased cellular senescence in the urothelial layer of the bladder; however, whether this phenomenon is the cause or effect of DBD is unknown. The urothelial layer of the bladder is made up of transitional epithelia specialized to contract and expand with demand and plays an active role in transmission by modulating afferent activity. Transition from normal functioning urothelial cells to secretory senescence cells would not only disrupt the barrier function of this layer but may result in altered signaling and sensation of bladder fullness; dysfunction of this layer is known to result in symptoms of frequency and urgency. Future DBD therapeutics may benefit from targeting and preventing early transition of urothelial cells to senescent cells
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