The effects of the interaction of animals with children diagnosed with autism spectrum disorder and their families [abstract]

The CDC estimates that one in 110 children receive a diagnosis of Autism Spectrum Disorder (ASD) annually. Pet dogs have been found to be a social catalyst and service dogs have demonstrated measurable benefits for children with ASD. Given that 39% of American households have a dog, this survey investigates the perceived benefits and barriers of having a dog in a family with a child with ASD

Walk A Hound, Lose A Pound, & Stay Fit for Seniors

Comparative Medicine - OneHealth and Comparative Medicine Poster SessionBackground: Obesity rates in older adults are linked with the national problem of limited physical activity (PA), resulting in chronic illness. Obesity-related illness and functional loss require innovative interventions. Older adult dog walkers maintained physical functioning over a 3 year period (Thorpe 2006). Dog walking may improve long-term PA by improving readiness and physical function. Purpose: The study aimed to test the association between dog walking and physical functioning. Methods: A three-group, repeated measures design tested efficacy of a 12-week (5 days/week) shelter dog walking program for community-dwelling adults over age 65. Three retirement facilities were assigned to the shelter dog walking (DW), human walking companion (HWC), or no-treatment control (C) group. DW group members selected a dog matching their walking capability & walked on a paved road at the animal shelter. HWC group members walked with a friend or spouse on a paved road at their residence. Both groups were accompanied by study staff. Pretest, mid-trial & posttest findings included 6-minute walk, weight, physical activity during the previous week, physical activity stage of change, mood & social support. Findings: Fifty-four adults participated {DW n=12, HWC n=23 & C n=19}. Fourteen males & 40 females, ranged in age from 67-97 years (Mean=85). The 6-minute walk compared pre and post for the DW group increased 28% (p=0.012), the HWC had a 4% increase (p=0.32) and the C group a 6% increase (p=0.18). Conclusions: DW group participants expressed affinity for the shelter dogs. The DW group's walking ability improved significantly. They stated that their balance & walking confidence improved. They stated that they liked the program because it “gets me out,” “is helping me to feel more confident,” & “is fun.” Dog walking may be beneficial to improve or maintain functioning in older adults. Walking speed is an important indicator of balance

Shelter Dog Behavior Improvement: Dog Walking as Enrichment

Comparative Medicine - OneHealth and Comparative Medicine Poster SessionBackground: Several million dogs are euthanized in animal shelters annually after multiple relinquishment reasons (Scarlett, 2002; Salman, 1998; New, 2000 & Kass, 2001). Gains in pet adoptions are happening via shelter enrichment programs. We hypothesized that shelter dogs participating in a daily dog walking program involving elderly citizens, would have better behavior, higher adoption rates, and decreased euthanasia rates than dogs in a control group not in the walking program. Methods: All participant dogs were pre-qualified for walking through the standard shelter behavioral assessment for adoption. The dogs, at least one year of age were matched with a control dog for size (small, medium and large). The experimental group walked with an older adult five days a week. The control group of dogs did not walk. Pre-test and daily behavior scores were assigned. The length of time each dog spent in the shelter was recorded as were adoption, move to foster care, release to a breed rescue group or euthanasia outcomes. Results: There were 84 dog pairs. Outcomes for the experimental (walking) group: adoption n=58, to foster/rescue n=13, euthanized n=7. For the control group: adoption n=26, to foster/rescue n=28, and euthanized n=20. A chi-square test showed that the experimental group had significantly more adoptions (p<0.0001) and fewer euthanasias (p=.0063) than the control group. The control group had significantly more dogs that went to breed rescue networks (p=.00071) than did the experimental group. The control group had a higher total behavior score (exhibited more negative behavior). The Wilcoxon rank sum test was used to compare the experimental and control groups in terms of total behavior scores. Dogs in the experimental group had significantly better behavior than dogs in the control group (p=<0.0001). Conclusions: The dog walking program was associated with desired dog behavior outcomes, better adoption rates and lower euthanasia rates

The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma

Five years after the last prostatic carcinoma grading consensus conference of the International Society of Urological Pathology (ISUP), accrual of new data and modification of clinical practice require an update of current pathologic grading guidelines. This manuscript summarizes the proceedings of the ISUP consensus meeting for grading of prostatic carcinoma held in September 2019, in Nice, France. Topics brought to consensus included the following: (1) approaches to reporting of Gleason patterns 4 and 5 quantities, and minor/tertiary patterns, (2) an agreement to report the presence of invasive cribriform carcinoma, (3) an agreement to incorporate intraductal carcinoma into grading, and (4) individual versus aggregate grading of systematic and multiparametric magnetic resonance imaging-targeted biopsies. Finally, developments in the field of artificial intelligence in the grading of prostatic carcinoma and future research perspectives were discussed

Reporting Practices and Resource Utilization in the Era of Intraductal Carcinoma of the Prostate: A Survey of Genitourinary Subspecialists

Intraductal carcinoma of the prostate (IDC-P) has been recently recognized by the World Health Organization classification of prostatic tumors as a distinct entity, most often occurring concurrently with invasive prostatic adenocarcinoma (PCa). Whether documented admixed with PCa or in its rare pure form, numerous studies associate this entity with clinical aggressiveness. Despite increasing clinical experience and requirement of IDC-P documentation in protocols for synoptic reporting, the specifics of its potential contribution to assessment of grade group (GG) and cancer quantitation of PCa in both needle biopsies (NBx) and radical prostatectomy (RP) specimens remain unclear. Moreover, there are no standard guidelines for incorporating basal cell marker immunohistochemistry (IHC) in the diagnosis of IDC-P, either alone or as part of a cocktail with AMACR/racemase. An online survey containing 26 questions regarding diagnosis, reporting practices, and IHC resource utilization, focusing on IDC-P, was undertaken by 42 genitourinary subspecialists from 9 countries. The degree of agreement or disagreement regarding approaches to individual questions was classified as significant majority (\u3e75%), majority (51% to 75%), minority (26% to 50%) and significant minority (≤25%). IDC-P with or without invasive cancer is considered a contraindication for active surveillance by the significant majority (95%) of respondents, although a majority (66%) also agreed that the clinical significance/behavior of IDC-P on NBx or RP with PCa required further study. The majority do not upgrade PCa based on comedonecrosis seen only in the intraductal component in NBx (62%) or RP (69%) specimens. Similarly, recognizable IDC-P with GG1 PCa was not a factor in upgrading in NBx (78%) or RP (71%) specimens. The majority (60%) of respondents include readily recognizable IDC-P in assessment of linear extent of PCa at NBx. A significant majority (78%) would use IHC to confirm or exclude intraductal carcinoma if other biopsies showed no PCa, while 60% would use it to confirm IDC-P with invasive PCa in NBx if it would change the overall GG assignment. Nearly half (48%, a minority) would use IHC to confirm IDC-P for accurate Gleason pattern 4 quantitation. A majority (57%) report the percentage of IDC-P when present, in RP specimens. When obvious Gleason pattern 4 or 5 PCa is present in RP or NBx, IHC is rarely to almost never used to confirm the presence of IDC-P by the significant majority (88% and 90%, respectively). Most genitourinary pathologists consider IDC-P to be an adverse prognostic feature independent of the PCa grade, although recommendations for standardization are needed to guide reporting of IDC-P vis a vis tumor quantitation and final GG assessment. The use of IHC varies widely and is performed for a multitude of indications, although it is used most frequently in scenarios where confirmation of IDC-P would impact the GG assigned. Further study and best practices recommendations are needed to provide guidance with regards to the most appropriate indications for IHC use in scenarios regarding IDC-P