7,118 research outputs found
N=2 Gauge Theories: Congruence Subgroups, Coset Graphs and Modular Surfaces
We establish a correspondence between generalized quiver gauge theories in
four dimensions and congruence subgroups of the modular group, hinging upon the
trivalent graphs which arise in both. The gauge theories and the graphs are
enumerated and their numbers are compared. The correspondence is particularly
striking for genus zero torsion-free congruence subgroups as exemplified by
those which arise in Moonshine. We analyze in detail the case of index 24,
where modular elliptic K3 surfaces emerge: here, the elliptic j-invariants can
be recast as dessins d'enfant which dictate the Seiberg-Witten curves.Comment: 42+1 pages, 5 figures; various helpful comments incorporate
Siderophilic Cyanobacteria for the Development of Extraterrestrial Photoautotrophic Biotechnologies
In-situ production of consumables (mainly oxygen) using local resources (In-Situ Resource Utilization-ISRU) will significantly facilitate current plans for human exploration and settlement of the solar system, starting with the Moon. With few exceptions, nearly all technologies developed to date have employed an approach based on inorganic chemistry. None of these technologies include concepts for integrating the ISRU system with a bioregenerative life support system and a food production system. Therefore, a new concept based on the cultivation of cyanobacteria (CB) in semi-closed biogeoreactor, linking ISRU, a biological life support system, and food production, has been proposed. The key feature of the biogeoreactor is to use lithotrophic CB to extract many needed elements such as Fe directly from the dissolved regolith and direct them to any technological loop at an extraterrestrial outpost. Our studies showed that siderophilic (Fe-loving) CB are capable to corrode lunar regolith stimulants because they secrete chelating agents and can tolerate [Fe] up to 1 mM. However, lunar and Martian environments are very hostile (very high UV and gamma-radiation, extreme temperatures, deficit of water). Thus, the selection of CB species with high potential for extraterrestrial biotechnologies that may be utilized in 15 years must be sponsored by NASA as soon as possible. The study of the genomes of candidate CB species and the metagenomes of the terrestrial environments which they inhabit is critical to make this decision. Here we provide preliminary results about peculiarities of the genomes of siderophilic CB revealed by analyzing the genome of siderophilic cyanobacterium JSC-1 and the metagenome of iron depositing hot spring (IDHS) Chocolate Pots (Yellowstone National Park, Wyoming, USA). It has been found that IDHS are richer with ferrous iron than the majority of hot springs around the world. Fe2+ is known to increase the magnitude of oxidative stress in prokaryotes through so called Fenton reaction. It is not surprising therefore that the CB inhabiting IDHS have larger sets of the proteins involved in the maintenance of Fe homeostasis and oxidative stress protection than non-siderophilic CB. This finding combined with our earlier results about the ability of some siderophilic CB to utilize chemical elements released from analogs of lunar and Martian regolith make them the most advanced candidates to be employed in advanced extraterrestrial biotechnologies
Supporting reinterpretation in computer-aided conceptual design
This paper presents research that aims to inform the development of computational tools that better support design exploration and idea transformation - key objectives in conceptual design. Analyses of experimental data from two fields - product design and architecture - suggest that the interactions of designers with their sketches can be formalised according to a finite number of generalised shape rules defined within a shape grammar. Such rules can provide a basis for the generation of alternative design concepts and they have informed the development of a prototype shape synthesis system that supports dynamic reinterpretation of shapes in design activity. The notion of 'sub-shapes' is introduced and the significance of these to perception, recognition and the development of emergent structures is discussed. The paper concludes with some speculation on how such a system might find application in a range of design fields
Stakeholder perspectives on the development of a virtual clinic for diabetes care : qualitative study
Background: The development of the Internet has created new opportunities for health care provision, including its use as a
tool to aid the self-management of chronic conditions. We studied stakeholder reactions to an Internet-based “virtual clinic,”
which would allow people with diabetes to communicate with their health care providers, find information about their condition,
and share information and support with other users.
Objective: The aim of the study was to present the results of a detailed consultation with a variety of stakeholder groups in
order to identify what they regard as the desirable, important, and feasible characteristics of an Internet-based intervention to aid
diabetes self-management.
Methods: Three focus groups were conducted with 12 people with type 1 diabetes who used insulin pumps. Participants were
recruited through a local diabetes clinic. One-on-one interviews were conducted with 5 health care professionals from the same
clinic (2 doctors, 2 nurses, 1 dietitian) and with 1 representative of an insulin pump company. We gathered patient consensus via
email on the important and useful features of Internet-based systems used for other chronic conditions (asthma, epilepsy, myalgic
encephalopathy, mental health problems). A workshop to gather expert consensus on the use of information technology to improve
the care of young people with diabetes was organized.
Results: Stakeholder groups identified the following important characteristics of an Internet-based virtual clinic: being grounded
on personal needs rather than only providing general information; having the facility to communicate with, and learn from, peers;
providing information on the latest developments and news in diabetes; being quick and easy to use. This paper discusses these
characteristics in light of a review of the relevant literature. The development of a virtual clinic for diabetes that embodies these
principles, and that is based on self-efficacy theory, is described.
Conclusions: Involvement of stakeholders is vital early in the development of a complex intervention. Stakeholders have clear
and relevant views on what a virtual clinic system should provide, and these views can be captured and synthesized with relative
ease. This work has led to the design of a system that is able to meet user needs and is currently being evaluated in a pilot study
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Beagle to the Moon: nn experiment package to measure polar ice and volatiles in permanently shadowed areas or beneath the lunar surface
The Beagle Science Package is a flight qualified set of instruments which should be deployed to the lunar surface to answer the questions about water and volatiles present in permanently shadowed regions and/or beneath the surface
Direct imaging of a digital-micromirror device for configurable microscopic optical potentials
Programable spatial light modulators (SLMs) have significantly advanced the
configurable optical trapping of particles. Typically, these devices are
utilized in the Fourier plane of an optical system, but direct imaging of an
amplitude pattern can potentially result in increased simplicity and
computational speed. Here we demonstrate high-resolution direct imaging of a
digital micromirror device (DMD) at high numerical apertures (NA), which we
apply to the optical trapping of a Bose-Einstein condensate (BEC). We utilise a
(1200 x 1920) pixel DMD and commercially available 0.45 NA microscope
objectives, finding that atoms confined in a hybrid optical/magnetic or
all-optical potential can be patterned using repulsive blue-detuned (532 nm)
light with 630(10) nm full-width at half-maximum (FWHM) resolution, within 5%
of the diffraction limit. The result is near arbitrary control of the density
the BEC without the need for expensive custom optics. We also introduce the
technique of time-averaged DMD potentials, demonstrating the ability to produce
multiple grayscale levels with minimal heating of the atomic cloud, by
utilising the high switching speed (20 kHz maximum) of the DMD. These
techniques will enable the realization and control of diverse optical
potentials for superfluid dynamics and atomtronics applications with quantum
gases. The performance of this system in a direct imaging configuration has
wider application for optical trapping at non-trivial NAs.Comment: 9 page
Signatures of Pseudoscalar Photon Mixing in CMB Radiation
We model the effect of photon and ultra-light pseudoscalar mixing on the
propagation of electromagnetic radiation through the extragalactic medium. The
medium is modelled as a large number of magnetic domains, uncorrelated with one
another. We obtain an analytic expression for the different Stokes parameters
in the limit of small mixing angle. The different Stokes parameters are found
to increase linearly with the number of domains. We also verify this result by
direct numerical simulations. We use this formalism to estimate the effect of
pseudoscalar-photon mixing on the Cosmic Microwave Background (CMB)
polarization. We impose limits on the model parameters by the CMB observations.
We find that the currently allowed parameter range admits a CMB circular
polarization up to order .Comment: 17 pages, 5 figure
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