8,461 research outputs found

    More than just friends? Facebook, disclosive ethics and the morality of technology

    Get PDF
    Social networking sites have become increasingly popular destinations for people wishing to chat, play games, make new friends or simply stay in touch. Furthermore, many organizations have been quick to grasp the potential they offer for marketing, recruitment and economic activities. Nevertheless, counterclaims depict such spaces as arenas where deception, social grooming and the posting of defamatory content flourish. Much research in this area has focused on the ends to which people deploy the technology, and the consequences arising, with a view to making policy recommendations and ethical interventions. In this paper, we argue that tracing where morality lies is more complex than these efforts suggest. Using the case of a popular social networking site, and concepts about the morality of technology, we disclose the ethics of Facebook as diffuse and multiple. In our conclusions we provide some reflections on the possibilities for action in light of this disclosure

    Palliative care: promoting general practice participation

    Get PDF
    Specialist palliative care services and services involved in the pre-palliative phase of a patient’s disease must accept GPs as an integral part of the care tea

    Informed consent comprehension in African research settings

    No full text
    ObjectivePrevious reviews on participants' comprehension of informed consent information have focused on developed countries. Experience has shown that ethical standards developed on Western values may not be appropriate for African settings where research concepts are unfamiliar. We undertook this review to describe how informed consent comprehension is defined and measured in African research settings.MethodsWe conducted a comprehensive search involving five electronic databases: Medline, Embase, Global Health, EthxWeb and Bioethics Literature Database (BELIT). We also examined African Index Medicus and Google Scholar for relevant publications on informed consent comprehension in clinical studies conducted in sub-Saharan Africa. 29 studies satisfied the inclusion criteria; meta-analysis was possible in 21 studies. We further conducted a direct comparison of participants' comprehension on domains of informed consent in all eligible studies.ResultsComprehension of key concepts of informed consent varies considerably from country to country and depends on the nature and complexity of the study. Meta-analysis showed that 47% of a total of 1633 participants across four studies demonstrated comprehension about randomisation (95% CI 13.9–80.9%). Similarly, 48% of 3946 participants in six studies had understanding about placebo (95% CI 19.0–77.5%), while only 30% of 753 participants in five studies understood the concept of therapeutic misconception (95% CI 4.6–66.7%). Measurement tools for informed consent comprehension were developed with little or no validation. Assessment of comprehension was carried out at variable times after disclosure of study information. No uniform definition of informed consent comprehension exists to form the basis for development of an appropriate tool to measure comprehension in African participants.ConclusionsComprehension of key concepts of informed consent is poor among study participants across Africa. There is a vital need to develop a uniform definition for informed consent comprehension in low literacy research settings in Africa. This will be an essential step towards developing appropriate tools that can adequately measure informed consent comprehension. This may consequently suggest adequate measures to improve the informed consent procedure.ObjectifLes normes Ă©thiques Ă©laborĂ©es selon les valeurs occidentales ne sont peut-ĂȘtre pas appropriĂ©es au contexte africain oĂč les concepts de recherche ne sont pas familiers. Cette revue dĂ©crit comment la comprĂ©hension du consentement Ă©clairĂ© est dĂ©finie et mesurĂ©e dans les cadres de recherche africains.MĂ©thodesDes recherches ont Ă©tĂ© effectuĂ©es sur Medline, Embase, Global Health, EthxWeb, base de donnĂ©es de la BioĂ©thique LittĂ©rature, Index Medicus African et Google Scholar pour des publications pertinentes sur la comprĂ©hension du consentement Ă©clairĂ© dans les Ă©tudes cliniques menĂ©es en Afrique sub-saharienne. 29 Ă©tudes rĂ©pondaient aux critĂšres d'inclusion; une mĂ©ta-analyse a Ă©tĂ© possible pour 21 Ă©tudes. La comprĂ©hension des participants sur les domaines du consentement Ă©clairĂ© dans toutes les Ă©tudes admissibles a Ă©tĂ© comparĂ©e directement.RĂ©sultatsLa comprĂ©hension des concepts clĂ©s du consentement Ă©clairĂ© varie considĂ©rablement selon les pays et dĂ©pend de la nature et de la complexitĂ© de l’étude. La mĂ©ta-analyse a montrĂ© que 47% des participants ont compris la randomisation (IC95%: 13,9 - 80,9%), 48% ont compris le placebo (IC95%: 19,0 - 77,5%), 30% ont compris le concept de mĂ©prise thĂ©rapeutique (IC95%: 4,6 - 66,7%). Les outils de mesure de la comprĂ©hension du consentement Ă©clairĂ© Ă©taient dĂ©veloppĂ©s avec peu ou pas de validation.ConclusionsLa comprĂ©hension des concepts clĂ©s du consentement Ă©clairĂ© est faible en Afrique. Il y a une nĂ©cessitĂ© vitale d’élaborer une dĂ©finition uniforme pour la comprĂ©hension du consentement Ă©clairĂ© dans les cadres de recherche avec un faible niveau d'alphabĂ©tisation en Afrique.ObjetivoLos estĂĄndares Ă©ticos desarrollados basĂĄndose en valores occidentales podrĂ­an no ser apropiados para emplazamientos Africanos en donde los conceptos de investigaciĂłn no son familiares. En esta revisiĂłn se describe como la comprensiĂłn del consentimiento informado se define y mide en un centro de investigaciĂłn Africano.MĂ©todosSe buscaron publicaciones relevantes sobre la comprensiĂłn del consentimiento informado en estudios clĂ­nicos en África subsahariana en Medline, Embase, Global Health, EthxWeb, Bioethics Literature Database, African Index Medicus y Google Scholar. 29 estudios satisfacĂ­an los criterios de inclusiĂłn y el metaanĂĄlisis era posible para 21. La comprensiĂłn del consentimiento informado por parte de los participantes se comparĂł directamente en todos los estudios elegibles.ResultadosLa comprensiĂłn de conceptos claves del consentimiento informado variĂł de forma considerable entre paĂ­ses, y dependĂ­a de la naturaleza y de la complejidad del estudio. El meta-anĂĄlisis mostrĂł que un 47% entendĂ­a la aleatorizaciĂłn (IC 95% 13.9-80.9%); un 48% entendĂ­a el placebo (IC 95% 19.0-77.5%); y un 30% entendiĂł el concepto terapĂ©utico errado (IC 95% 4.6-66.7%). Las herramientas para medir la comprensiĂłn del consentimiento informado se desarrollaron con poca o ninguna validaciĂłn.ConclusionesEn África, la comprensiĂłn de conceptos claves del consentimiento informado es pobre. Existe una necesidad vital de desarrollar una definiciĂłn uniforme para la comprensiĂłn del consentimiento informado en lugares con bajos niveles de alfabetizaciĂłn en África

    The art of HIV elimination: past and present science

    Get PDF
    Introduction: Remarkable strides have been made in controlling the HIV epidemic, although not enough to achieve epidemic control. More recently, interest in biomedical HIV control approaches has increased, but substantial challenges with the HIV cascade of care hinder successful implementation. We summarise all available HIV prevention methods and make recommendations on how to address current challenges. Discussion: In the early days of the epidemic, behavioural approaches to control the HIV dominated, and the few available evidence-based interventions demonstrated to reduce HIV transmission were applied independently from one another. More recently, it has become clear that combination prevention strategies targeted to high transmission geographies and people at most risk of infections are required to achieve epidemic control. Biomedical strategies such as male medical circumcision and antiretroviral therapy for treatment in HIV-positive individuals and as preexposure prophylaxis in HIV-negative individuals provide immense promise for the future of HIV control. In resourcerich settings, the threat of HIV treatment optimism resulting in increased sexual risk taking has been observed and there are concerns that as ART roll-out matures in resource-poor settings and the benefits of ART become clearly visible, behavioural disinhibition may also become a challenge in those settings. Unfortunately, an efficacious vaccine, a strategy which could potentially halt the HIV epidemic, remains elusive. Conclusion: Combination HIV prevention offers a logical approach to HIV control, although what and how the available options should be combined is contextual. Therefore, knowledge of the local or national drivers of HIV infection is paramount. Problems with the HIV care continuum remain of concern, hindering progress towards the UNAIDS target of 90-90-90 by 2020. Research is needed on combination interventions that address all the steps of the cascade as the steps are not independent of each other. Until these issues are addressed, HIV elimination may remain an unattainable goal

    Jovian equatorial H2 emission from 1979-1987

    Get PDF
    Ninety two IUE observations of the Jovian equatorial region taken between 2 Dec. 1978 and 1 Feb. 1988 were averaged together by date of observation, resulting in 22 averaged spectra which were fit with a model to determine the amount of H2 Lyman band emission in the region 1552 to 1624A. The data suggest that the H2 emission may vary with time. Especially suggestive is the marked downward trend of the emission between 1983 and 1987, during which time the strength of the emission in the 1552 to 1624A region decreases by a factor of 10. Uncertainty in the existing data and a gap in the data in 1980 and 1981 preclude a positive identification of a correlation between the brightness of the H2 emission and the major solar cycle

    Low-energy electron diffraction study of potassium adsorbed on single-crystal graphite and highly oriented pyrolytic graphite

    Get PDF
    Potassium adsorption on graphite has been a model system for the understanding of the interaction of alkali metals with surfaces. The geometries of the s232d structure of potassium on both single-crystal graphite (SCG) and highly oriented pyrolytic graphite (HOPG) were investigated for various preparation conditions for graphite temperatures between 55 and 140 K. In all cases, the geometry was found to consist of K atoms in the hollow sites on top of the surface. The K-graphite average perpendicular spacing is 2.79±0.03 Å, corresponding to an average C-K distance of 3.13±0.03 Å, and the spacing between graphite planes is consistent with the bulk spacing of 3.35 Å. No evidence was observed for a sublayer of potassium. The results of dynamical LEED studies for the clean SCG and HOPG surfaces indicate that the surface structures of both are consistent with the truncated bulk structure of graphite

    Coverage-dependent structural phase transformations in the adsorption of pentacene on an aperiodically modulated Cu film

    Get PDF
    Surface ordering of pentacene molecules adsorbed on an aperiodic Cu surface has been studied with density functional theory (DFT) and scanning tunnelling microscopy as a function of coverage. Below 0.73 ML (5.3 × 1013 molecules cm−2), the adsorbate structure is row-like with the molecular axes aligned with the rows in the Cu structure. Between this coverage and 1 ML (7.3 × 1013 molecules cm−2), a structural phase with a checkerboard structure is seen. At this coverage region, the molecules are very close to each other which leads to unusual bending. At higher coverages, a further phase transition to a high-density row structure is seen for most of the film. DFT with van der Waals functionals is employed to study how the molecule-molecule and molecule-surface interactions evolve as a function of coverage
    • 

    corecore