2,283 research outputs found
Stepping on untreaded waters: a grounded theory approach to paediatric nurses' experience of caring for young people who self-harm
Running a distributed virtual observatory: US Virtual Astronomical Observatory operations
Operation of the US Virtual Astronomical Observatory shares some issues with
modern physical observatories, e.g., intimidating data volumes and rapid
technological change, and must also address unique concerns like the lack of
direct control of the underlying and scattered data resources, and the
distributed nature of the observatory itself. In this paper we discuss how the
VAO has addressed these challenges to provide the astronomical community with a
coherent set of science-enabling tools and services. The distributed nature of
our virtual observatory-with data and personnel spanning geographic,
institutional and regime boundaries-is simultaneously a major operational
headache and the primary science motivation for the VAO. Most astronomy today
uses data from many resources. Facilitation of matching heterogeneous datasets
is a fundamental reason for the virtual observatory. Key aspects of our
approach include continuous monitoring and validation of VAO and VO services
and the datasets provided by the community, monitoring of user requests to
optimize access, caching for large datasets, and providing distributed storage
services that allow user to collect results near large data repositories. Some
elements are now fully implemented, while others are planned for subsequent
years. The distributed nature of the VAO requires careful attention to what can
be a straightforward operation at a conventional observatory, e.g., the
organization of the web site or the collection and combined analysis of logs.
Many of these strategies use and extend protocols developed by the
international virtual observatory community.Comment: 7 pages with 2 figures included within PD
Using Virtual Observatory Services in Sky View
For over a decade Skyview has provided astronomers and the public with easy access to survey and imaging data from all wavelength regimes. SkyView has pioneered many of the concepts that underlie the Virtual Observatory. Recently SkyView has been released as a distributable package which uses VO protocols to access image and catalog services. This chapter describes how to use the Skyview as a local service and how to customize it to access additional VO services and local data
Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus
RecG is a DNA translocase encoded by most species of bacteria. The Escherichia coli protein targets branched DNA substrates and drives the unwinding and rewinding of DNA strands. Its ability to remodel replication forks and to genetically interact with PriA protein have led to the idea that it plays an important role in securing faithful genome duplication. Here we report that RecG co-localises with sites of DNA replication and identify conserved arginine and tryptophan residues near its C-terminus that are needed for this localisation. We establish that the extreme C-terminus, which is not resolved in the crystal structure, is vital for DNA unwinding but not for DNA binding. Substituting an alanine for a highly conserved tyrosine near the very end results in a substantial reduction in the ability to unwind replication fork and Holliday junction structures but has no effect on substrate affinity. Deleting or substituting the terminal alanine causes an even greater reduction in unwinding activity, which is somewhat surprising as this residue is not uniformly present in closely related RecG proteins. More significantly, the extreme C-terminal mutations have little effect on localisation. Mutations that do prevent localisation result in only a slight reduction in the capacity for DNA repair. © 2014 The Author(s)
A Prediction of Observable Rotation in the ICM of Abell 3266
We present a numerical Hydro+N-body model of A3266 whose X-ray surface
brightness, temperature distribution, and galaxy spatial and velocity
distribution data are consistent with the A3266 data. The model is an old (~3
Gyr), off-axis merger having a mass ratio of ~2.5:1. The less massive
subcluster in the model is moving on a trajectory from southwest to northeast
passing on the western side of the dominant cluster while moving into the plane
of the sky at ~45 degrees. Off-axis mergers such as this one are an effective
mechanism for transferring angular momentum to the intracluster medium (ICM),
making possible a large scale rotation of the ICM. We demonstrate here that the
ICM rotation predicted by our fully 3-dimensional model of A3266 is observable
with current technology. As an example, we present simulated observations
assuming the capabilities of the high resolution X-ray spectrometer (XRS) which
was to have flown on Astro-E.Comment: 9 pages, 7 postscript figures, Fig. 3 and 6 are color postscript,
Accepted for publication in the Astrophysical Journa
OMCat: Catalogue of Serendipitous Sources Detected with the XMM-Newton Optical Monitor
The Optical Monitor Catalogue of serendipitous sources (OMCat) contains
entries for every source detected in the publicly available XMM-Newton Optical
Monitor (OM) images taken in either the imaging or ``fast'' modes. Since the OM
is coaligned and records data simultaneously with the X-ray telescopes on
XMM-Newton, it typically produces images in one or more near-UV/optical bands
for every pointing of the observatory. As of the beginning of 2006, the public
archive had covered roughly 0.5% of the sky in 2950 fields.
The OMCat is not dominated by sources previously undetected at other
wavelengths; the bulk of objects have optical counterparts. However, the OMCat
can be used to extend optical or X-ray spectral energy distributions for known
objects into the ultraviolet, to study at higher angular resolution objects
detected with GALEX, or to find high-Galactic-latitude objects of interest for
UV spectroscopy.Comment: 25 pages, 22 figures, submitted to PAS
Inverse Magnetoresistance of Molecular Junctions
We present calculations of spin-dependent electron transport through single
organic molecules bridging pairs of iron nanocontacts. We predict the
magnetoresistance of these systems to switch from positive to negative with
increasing applied bias for both conducting and insulating molecules. This
novel inverse magnetoresistance phenomenon is robust, does not depend on the
presence of impurities, and is unique to molecular and atomic nanoscale
magnetic junctions. Its physical origin is identified and its relevance to
experiment and to potential technological applications is discussed.Comment: 5 pages, 3 figures; published version Phys. Rev.
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