4,178 research outputs found
AGRICULTURAL ECONOMICS PROGRAMS AT 1890 INSTITUTIONS: CURRENT STATUS AND FUTURE DIRECTIONS
Teaching/Communication/Extension/Profession,
Complexity-based learning and teaching: a case study in higher education
This paper presents a learning and teaching strategy based on complexity science and explores its impacts on a higher education game design course. The strategy aimed at generating conditions fostering individual and collective learning in educational complex adaptive systems, and led the design of the course through an iterative and adaptive process informed by evidence emerging from course dynamics. The data collected indicate that collaboration was initially challenging for students, but collective learning emerged as the course developed, positively affecting individual and team performance. Even though challenged, students felt highly motivated and enjoyed working on course activities. Their perception of progress and expertise were always high, and the academic performance was on average very good. The strategy fostered collaboration and allowed students and tutors to deal with complex situations requiring adaptation
Potential of Deshi Cattle of India for Dairy Production
There were 1,405 lactation records of 336 cows at the Central Livestock Research- cum-Breeding Station, Haringhata, India from 1958 to 1968 used to estimate the potential dairy merit of Deshi cattle. This breed is native to northeast India and one of the smallest breeds in India (mature females 200 kg and males 250 kg). Averages and standard deviations for milk yield (exclusive of that suckled), age of first calving, calving interval, lactation length, days open, and days dry were 412 ± 178 kg, 44.5 ± 6.8 months, 419 ± 90 days, 264 ± 81 days, 135 ± 86 days, and 139 ± 80 days. Mortality, culling, and retention rates for females from birth to first calving were 24, 27, and 49%. Lactation number, season of calving, and death of calf early in lactation had significant effects on milk yield. Repeatabilities of milk yield, lactation length, calving interval, dry period, and days open were .42, .19, .21, .03, and .23 with corresponding heritabilities .64, .19, .09, .19, and .27. Heritability for age of first calving was .84. Confounding by some environmental effects probably biased heritability estimates upward. Potential genetic improvement of milk yield by mass selection was estimated at .8% per year. Contemporary Jersey X Deshi crosses exceeded Deshi for milk yield, age of first calving, lactation length, calving interval, and days open by +923 kg, -15 months, +41, -84, and -96 days. At least one generation of crossing with European breeds is recommended over mass selection of Deshi
On Exchange of Orbital Angular Momentum Between Twisted Photons and Atomic Electrons
We obtain an expression for the matrix element for a twisted
(Laguerre-Gaussian profile) photon scattering from a hydrogen atom. We consider
photons incoming with an orbital angular momentum (OAM) of ,
carried by a factor of not present in a plane-wave or pure
Gaussian profile beam. The nature of the transfer of units of OAM from
the photon to the azimuthal atomic quantum number of the atom is investigated.
We obtain simple formulae for these OAM flip transitions for elastic forward
scattering of twisted photons when the photon wavelength is large
compared with the atomic target size , and small compared the Rayleigh range
, which characterizes the collimation length of the twisted photon beam.Comment: 16 page
Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front
Neural crest (NC) cell migration is crucial to the formation of peripheral tissues during vertebrate development. However, how NC cells respond to different microenvironments to maintain persistence of direction and cohesion in multicellular streams remains unclear. To address this, we profiled eight subregions of a typical cranial NC cell migratory stream. Hierarchical clustering showed significant differences in the expression profiles of the lead three subregions compared with newly emerged cells. Multiplexed imaging of mRNA expression using fluorescent hybridization chain reaction (HCR) quantitatively confirmed the expression profiles of lead cells. Computational modeling predicted that a small fraction of lead cells that detect directional information is optimal for successful stream migration. Single-cell profiling then revealed a unique molecular signature that is consistent and stable over time in a subset of lead cells within the most advanced portion of the migratory front, which we term trailblazers. Model simulations that forced a lead cell behavior in the trailing subpopulation predicted cell bunching near the migratory domain entrance. Misexpression of the trailblazer molecular signature by perturbation of two upstream transcription factors agreed with the in silico prediction and showed alterations to NC cell migration distance and stream shape. These data are the first to characterize the molecular diversity within an NC cell migratory stream and offer insights into how molecular patterns are transduced into cell behaviors
p53-mediated delayed NF-ÎșB activity enhances etoposide-induced cell death in medulloblastoma
Medulloblastoma (MB) is an embryonic brain tumour that arises in the cerebellum. Using several MB cell lines, we have demonstrated that the chemotherapeutic drug etoposide induces a p53- and caspase-dependent cell death. We have observed an additional caspase-independent cell death mechanism involving delayed nuclear factor ÎșB (NF-ÎșB) activity. The delayed induction was controlled by a p53-dependent transcription step and the production of death receptors (especially CD95/Fas). We further demonstrated that in both MB and glioblastoma (GM) cell lines, in which the p53 pathway was not functional, no p65 activation could be detected upon etoposide treatment. MB cell lines that have mutations in p53 or NF-ÎșB are either less sensitive (NF-ÎșB mutant) or even completely resistant (p53 mutant) to chemotherapeutic intervention. The optimal cell death was only achieved when both p53 and NF-ÎșB were switched on. Taken together, our results shed light on the mechanism of NF-ÎșB activation by etoposide in brain tumours and show that the genetic background of MB and GM cells determines their sensitivity to chemotherapy and has to be taken into account for efficient therapeutic intervention
The Formation of the First Stars. I. The Primordial Star Forming Cloud
To constrain the nature of the very first stars, we investigate the collapse
and fragmentation of primordial, metal-free gas clouds. We explore the physics
of primordial star formation by means of three-dimensional simulations of the
dark matter and gas components, using smoothed particle hydrodynamics, under a
wide range of initial conditions, including the initial spin, the total mass of
the halo, the redshift of virialization, the power spectrum of the DM
fluctuations, the presence of HD cooling, and the number of particles employed
in the simulation. We find characteristic values for the temperature, T ~ a few
100 K, and the density, n ~ 10^3-10^4 cm^-3, characterising the gas at the end
of the initial free-fall phase. These values are rather insensitive to the
initial conditions. The corresponding Jeans mass is M_J ~ 10^3 M_sun. The
existence of these characteristic values has a robust explanation in the
microphysics of H2 cooling, connected to the minimum temperature that can be
reached with the H2 coolant, and to the critical density at which the
transition takes place betweeb levels being populated according to NLTE, and
according to LTE.
In all cases, the gas dissipatively settles into an irregular, central
configuration which has a filamentary and knotty appearance. The fluid regions
with the highest densities are the first to undergo runaway collapse due to
gravitational instability, and to form clumps with initial masses ~ 10^3 M_sun,
close to the characteristic Jeans scale. These results suggest that the first
stars might have been quite massive, possibly even very massive with M_star >
100 M_sun.Comment: Minor revisions. 26 pages, including 24 figures and 5 tables. ApJ, in
press. To appear in the Dec. 20, 2001 issue (v563
Cosmic Renaissance: The First Sources of Light
I review recent progress in understanding the formation of the first stars
and quasars. The initial conditions for their emergence are given by the now
firmly established model of cosmological structure formation. Numerical
simulations of the collapse and fragmentation of primordial gas indicate that
the first stars formed at redshifts z ~ 20 - 30, and that they were
predominantly very massive, with M_* > 100 M_sun. Important uncertainties,
however, remain. Paramount among them is the accretion process, which builds up
the final stellar mass by incorporating part of the diffuse, dust-free envelope
into the central protostellar core. The first quasars, on the other hand, are
predicted to have formed later on, at z ~ 10, in more massive dark matter
halos, with total masses, ~ 10^8 M_sun, characteristic of dwarf galaxies.Comment: 16 pages, 7 figures, invited review, to appear in PASP, Feb. 200
Dissolved organic carbon uptake in streams: A review and assessment of reachâscale measurements
Quantifying the role that freshwater ecosystems play in the global carbon cycle requires accurate measurement and scaling of dissolved organic carbon (DOC) removal in river networks. We reviewed reachâscale measurements of DOC uptake from experimental additions of simple organic compounds or leachates to inform development of aquatic DOC models that operate at the river network, regional, or continental scale. Median DOC uptake velocity (vf) across all measurements was 2.28âmmâminâ1. Measurements using simple compound additions resulted in faster vf (2.94âmmâminâ1) than additions of leachates (1.11âmmâminâ1). We also reviewed published data of DOC bioavailability for ambient stream water and leaf leachate DOC from laboratory experiments. We used these data to calculate and apply a correction factor to leaf leachate uptake velocity to estimate ambient stream water DOC uptake rates at the reach scale. Using this approach, we estimated a median ambient stream DOC vf of 0.26âmmâminâ1. Applying these DOC vf values (0.26, 1.11, 2.28, and 2.94âmmâminâ1) in a river network inverse model in seven watersheds revealed that our estimated ambient DOC vf value is plausible at the network scale and 27 to 45% of DOC input was removed. Applying the median measured simple compound or leachate vf in whole river networks would require unjustifiably high terrestrial DOC inputs to match observed DOC concentrations at the basin mouth. To improve the understanding and importance of DOC uptake in fluvial systems, we recommend using a multiscale approach coupling laboratory assays, with reachâscale measurements, and modeling
Discreet element modeling of under sleeper pads using a box test
It has recently been reported that under sleeper pads (USPs) could improve ballasted rail track by decreasing the sleeper settlement and reducing particle breakage. In order to find out what happens at the particle-pad interface, discrete element modelling (DEM) is used to provide micro mechanical insight. The same positive effects of USP are found in the DEM simulations. The evidence provided by DEM shows that application of a USP allows more particles to be in contact with the pad, and causes these particles to transfer a larger lateral load to the adjacent ballast but a smaller vertical load beneath the sleeper. This could be used to explain why the USP helps to reduce the track settlement. In terms of particle breakage, it is found that most breakage occurs at the particle-sleeper interface and along the main contact force chains between particles under the sleeper. The use of USPs could effectively reduce particle abrasion that occurs in both of these regions
- âŠ