People of immigrant and refugee background sharing experiences of mental health recovery: reflections and recommendations on using digital storytelling

Ten individuals of immigrant or refugee background, who had experi- enced mental health or emotional issues, participated in an immersive workshop to create digital stories as part of a national multicultural men- tal health initiative. Known collectively as ‘Finding our way’, the stories combine the power of first-person narrative with digital technologies. Three years on, six workshop participants and two coordinators reflect on the project’s effects, and offer recommendations for conducting and evaluating similar projects in the future. Individuals experienced the proj- ect as personally empowering. The stories have been used to facilitate community and service-based conversations about diversity, mental health and recovery

Recovering from mental illness and suicidal behaviour in a culturally diverse context: the use of digital storytelling in cross-cultural medical humanities and mental health

en people of immigrant and refugee background, with a lived experience of mental health or emotional issues, participated in a four-day digital storytelling workshop, to create a story that expressed something about their personal encounters with mental ill-health and recovery. As many other DST projects have done before, this project used the power of first-person narratives and provided an opportunity for ‘unheard voices to be heard’.The storytellers were supported to create their own accounts, share their experiences (in mainstream media, in policy and service settings, and for practitioner education), grow in self-confidence, and develop other capabilities.This chapter describes the DST process and discusses its impact from the perspective of the two project coordinators in consultation with six participants, five as storytellers and one support person. It also provides the perspective of a Mandarin-speaking participant in depth. The digital stories can be freely viewed at www.vtmh.org.au

Lived experiences of mental health recovery in persons of culturally and linguistically diverse (CALD) backgrounds within the Australian context

Lived experience research related to mental health recovery is advancing, but there remains a lack of narrative material from the perspectives of people from under-represented, non-dominant cultural backgrounds in this domain. This study aimed to explore the lived experiences of mental health recovery in people of culturally and linguistically diverse (CALD) backgrounds in the Australian context. The current study involved a secondary analysis of audio and visual data collected during the digital storytelling project Finding our way in Melbourne, Australia. Thematic analysis was used to understand the lived experience narratives of nine participants in relation to mental health recovery. Five themes were identified through an iterative process of analysis, including Newfound opportunities and care, Family as key motivators and facilitators, Coping and generativity, Cultivating self-understanding and resilience, and Empowerment through social engagement. First person lived experience narratives offer deep insight into understanding the ways in which individuals of marginalised communities conceptualise and embody recovery. These findings further the literature and understanding on how to better serve the needs of people with mental health challenges from CALD communities through informed knowledge of what may be helpful to, and meaningful in, individuals’ recoveries

The effectiveness of three types of practice in word recognition in grades II and III

Thesis (Ed.M.)--Boston Universit

Teleology and Realism in Leibniz's Philosophy of Science

This paper argues for an interpretation of Leibniz’s claim that physics requires both mechanical and teleological principles as a view regarding the interpretation of physical theories. Granting that Leibniz’s fundamental ontology remains non-physical, or mentalistic, it argues that teleological principles nevertheless ground a realist commitment about mechanical descriptions of phenomena. The empirical results of the new sciences, according to Leibniz, have genuine truth conditions: there is a fact of the matter about the regularities observed in experience. Taking this stance, however, requires bringing non-empirical reasons to bear upon mechanical causal claims. This paper first evaluates extant interpretations of Leibniz’s thesis that there are two realms in physics as describing parallel, self-sufficient sets of laws. It then examines Leibniz’s use of teleological principles to interpret scientific results in the context of his interventions in debates in seventeenth-century kinematic theory, and in the teaching of Copernicanism. Leibniz’s use of the principle of continuity and the principle of simplicity, for instance, reveal an underlying commitment to the truth-aptness, or approximate truth-aptness, of the new natural sciences. The paper concludes with a brief remark on the relation between metaphysics, theology, and physics in Leibniz

Geo-neutrinos: A systematic approach to uncertainties and correlations

Geo-neutrinos emitted by heat-producing elements (U, Th and K) represent a unique probe of the Earth interior. The characterization of their fluxes is subject, however, to rather large and highly correlated uncertainties. The geochemical covariance of the U, Th and K abundances in various Earth reservoirs induces positive correlations among the associated geo-neutrino fluxes, and between these and the radiogenic heat. Mass-balance constraints in the Bulk Silicate Earth (BSE) tend instead to anti-correlate the radiogenic element abundances in complementary reservoirs. Experimental geo-neutrino observables may be further (anti)correlated by instrumental effects. In this context, we propose a systematic approach to covariance matrices, based on the fact that all the relevant geo-neutrino observables and constraints can be expressed as linear functions of the U, Th and K abundances in the Earth's reservoirs (with relatively well-known coefficients). We briefly discuss here the construction of a tentative "geo-neutrino source model" (GNSM) for the U, Th, and K abundances in the main Earth reservoirs, based on selected geophysical and geochemical data and models (when available), on plausible hypotheses (when possible), and admittedly on arbitrary assumptions (when unavoidable). We use then the GNSM to make predictions about several experiments ("forward approach"), and to show how future data can constrain - a posteriori - the error matrix of the model itself ("backward approach"). The method may provide a useful statistical framework for evaluating the impact and the global consistency of prospective geo-neutrino measurements and Earth models.Comment: 17 pages, including 4 figures. To appear on "Earth, Moon, and Planets," Special Issue on "Neutrino Geophysics," Proceedings of Neutrino Science 2005 (Honolulu, Hawaii, Dec. 2005

Designing and Piloting a Tool for the Measurement of the Use of Pronunciation Learning Strategies

What appears to be indispensable to drive the field forward and ensure that research findings will be comparable across studies and provide a sound basis for feasible pedagogic proposals is to draw up a classification of PLS and design on that basis a valid and reliable data collection tool which could be employed to measure the use of these strategies in different groups of learners, correlate it with individual and contextual variables, and appraise the effects of training programs. In accordance with this rationale, the present paper represents an attempt to propose a tentative categorization of pronunciation learning strategies, adopting as a point of reference the existing taxonomies of strategic devices (i.e. O'Malley and Chamot 1990; Oxford 1990) and the instructional options teachers have at their disposal when dealing with elements of this language subsystem (e.g. Kelly 2000; Goodwin 2001). It also introduces a research instrument designed on the basis of the classification that shares a number of characteristics with Oxford's (1990) Strategy Inventory for Language Learning but, in contrast to it, includes both Likert-scale and open-ended items. The findings of a pilot study which involved 80 English Department students demonstrate that although the tool requires considerable refinement, it provides a useful point of departure for future research into PLS

Dissection, Culture, and Analysis of Xenopus laevis Embryonic Retinal Tissue

The process by which the anterior region of the neural plate gives rise to the vertebrate retina continues to be a major focus of both clinical and basic research. In addition to the obvious medical relevance for understanding and treating retinal disease, the development of the vertebrate retina continues to serve as an important and elegant model system for understanding neuronal cell type determination and differentiation(1-16). The neural retina consists of six discrete cell types (ganglion, amacrine, horizontal, photoreceptors, bipolar cells, and Muller glial cells) arranged in stereotypical layers, a pattern that is largely conserved among all vertebrates (12,14-18). While studying the retina in the intact developing embryo is clearly required for understanding how this complex organ develops from a protrusion of the forebrain into a layered structure, there are many questions that benefit from employing approaches using primary cell culture of presumptive retinal cells (7,19-23). For example, analyzing cells from tissues removed and dissociated at different stages allows one to discern the state of specification of individual cells at different developmental stages, that is, the fate of the cells in the absence of interactions with neighboring tissues (8,19-22,24-33). Primary cell culture also allows the investigator to treat the culture with specific reagents and analyze the results on a single cell level (5,8,21,24,27-30,33-39). Xenopus laevis, a classic model system for the study of early neural development (19,27,29,31-32,40-42), serves as a particularly suitable system for retinal primary cell culture (10,38,43-45). Presumptive retinal tissue is accessible from the earliest stages of development, immediately following neural induction (25,38,43). In addition, given that each cell in the embryo contains a supply of yolk, retinal cells can be cultured in a very simple defined media consisting of a buffered salt solution, thus removing the confounding effects of incubation or other sera-based products (10,24,44-45). However, the isolation of the retinal tissue from surrounding tissues and the subsequent processing is challenging. Here, we present a method for the dissection and dissociation of retinal cells in Xenopus laevis that will be used to prepare primary cell cultures that will, in turn, be analyzed for calcium activity and gene expression at the resolution of single cells. While the topic presented in this paper is the analysis of spontaneous calcium transients, the technique is broadly applicable to a wide array of research questions and approaches (Figure 1)

Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas.

Glioma is recognized to be a highly heterogeneous CNS malignancy, whose diverse cellular composition and cellular interactions have not been well characterized. To gain new clinical- and biological-insights into the genetically-bifurcated IDH1 mutant (mt) vs wildtype (wt) forms of glioma, we integrated data from protein, genomic and MR imaging from 20 treatment-naïve glioma cases and 16 recurrent GBM cases. Multiplexed immunofluorescence (MxIF) was used to generate single cell data for 43 protein markers representing all cancer hallmarks, Genomic sequencing (exome and RNA (normal and tumor) and magnetic resonance imaging (MRI) quantitative features (protocols were T1-post, FLAIR and ADC) from whole tumor, peritumoral edema and enhancing core vs equivalent normal region were also collected from patients. Based on MxIF analysis, 85,767 cells (glioma cases) and 56,304 cells (GBM cases) were used to generate cell-level data for 24 biomarkers. K-means clustering was used to generate 7 distinct groups of cells with divergent biomarker profiles and deconvolution was used to assign RNA data into three classes. Spatial and molecular heterogeneity metrics were generated for the cell data. All features were compared between IDH mt and IDHwt patients and were finally combined to provide a holistic/integrated comparison. Protein expression by hallmark was generally lower in the IDHmt vs wt patients. Molecular and spatial heterogeneity scores for angiogenesis and cell invasion also differed between IDHmt and wt gliomas irrespective of prior treatment and tumor grade; these differences also persisted in the MR imaging features of peritumoral edema and contrast enhancement volumes. A coherent picture of enhanced angiogenesis in IDHwt tumors was derived from multiple platforms (genomic, proteomic and imaging) and scales from individual proteins to cell clusters and heterogeneity, as well as bulk tumor RNA and imaging features. Longer overall survival for IDH1mt glioma patients may reflect mutation-driven alterations in cellular, molecular, and spatial heterogeneity which manifest in discernable radiological manifestations