74 research outputs found

    Increased OLED radiative efficiency using a directive optical antenna

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    Journal ArticleWe investigate the improvement in efficiency of organic light emitting diodes/displays (OLEDs) by embedding a typical OLED structure within a metallic patch grating resonator. A patch grating resonator is similar to the more familiar Fabry-Perot resonator, except that one mirror of the resonator is a metallic patch grating with a pitch ~ λ /2 that reduces lateral propagation of radiative emission. FDTD simulations of the proposed structure indicate a potential 71% increase in emitted power over that of a reference OLED structure, and an additional 5% gain from adding an ITO spacer adjacent to the metallic electrode layer (for a total 76% increase). Implementation of this structure requires little to no modification of the OLED manufacturing process

    Physiological Responses to Acute Cycling With Blood Flow Restriction

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    Aerobic exercise with blood flow restriction (BFR) can improve muscular function and aerobic capacity. However, the extent to which cuff pressure influences acute physiological responses to aerobic exercise with BFR is not well documented. We compared blood flow, tissue oxygenation, and neuromuscular responses to acute cycling with and without BFR. Ten participants completed four intermittent cycling (6 × 2 min) conditions: low-load cycling (LL), low-load cycling with BFR at 60% of limb occlusion pressure (BFR60), low-load cycling with BFR at 80% of limb occlusion pressure (BFR80), and high-load cycling (HL). Tissue oxygenation, cardiorespiratory, metabolic, and perceptual responses were assessed during cycling and blood flow was measured during recovery periods. Pre- to post-exercise changes in knee extensor function were also assessed. BFR60 and BFR80 reduced blood flow (~33 and ~ 50%, respectively) and tissue saturation index (~5 and ~15%, respectively) when compared to LL (all  \u3c 0.05). BFR60 resulted in lower VO, heart rate, ventilation, and perceived exertion compared to HL (all  \u3c 0.05), whereas BFR80 resulted in similar heart rates and exertion to HL (both  \u3e 0.05). BFR60 and BFR80 elicited greater pain compared to LL and HL (all  \u3c 0.05). After exercise, knee extensor torque decreased by ~18 and 40% for BFR60 and BFR80, respectively (both  \u3c 0.05), and was compromised mostly through peripheral mechanisms. Cycling with BFR increased metabolic stress, decreased blood flow, and impaired neuromuscular function. However, only BFR60 did so without causing very severe pain (\u3e8 on pain intensity scale). Cycling with BFR at moderate pressure may serve as a potential alternative to traditional high-intensity aerobic exercise

    Acoustical measurement of nonlinear internal waves using the inverted echo sounder

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    Author Posting. © American Meteorological Society, 2009. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Atmospheric and Oceanic Technology 26 (2009): 2228-2242, doi:10.1175/2009JTECHO652.1.The performance of pressure sensor–equipped inverted echo sounders for monitoring nonlinear internal waves is examined. The inverted echo sounder measures the round-trip acoustic travel time from the sea floor to the sea surface and thus acquires vertically integrated information on the thermal structure, from which the first baroclinic mode of thermocline motion may be inferred. This application of the technology differs from previous uses in that the wave period (30 min) is short, requiring a more rapid transmission rate and a different approach to the analysis. Sources of error affecting instrument performance include tidal effects, barotropic adjustment to internal waves, ambient acoustic noise, and sea surface roughness. The latter two effects are explored with a simulation that includes surface wave reconstruction, acoustic scattering based on the Kirchhoff approximation, wind-generated noise, sound propagation, and the instrument’s signal processing circuitry. Bias is introduced as a function of wind speed, but the simulation provides a basis for bias correction. The assumption that the waves do not significantly affect the mean stratification allows for a focus on the dynamic response. Model calculations are compared with observations in the South China Sea by using nearby temperature measurements to provide a test of instrument performance. After applying corrections for ambient noise and surface roughness effects, the inverted echo sounder exhibits an RMS variability of approximately 4 m in the estimated depth of the eigenfunction maximum in the wind speed range 0 ≤ U10 ≤ 10 m s−1. This uncertainty may be compared with isopycnal excursions for nonlinear internal waves of 100 m, showing that the observational approach is effective for measurements of nonlinear internal waves in this environment.This project was supported by the ONR Nonlinear Wave Program under Contract N0014-05-1-0286

    Investigation into New Ground Based Communications Service Offerings in Response to SmallSat Trends

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    The number of NASA sponsored Small Satellite (SmallSat) missions is expected to continue to grow rapidly in the next decade and beyond. There is a growing trend towards more ambitious SmallSat missions, including formation flying (Constellation, Cluster, Trailing) SmallSats and SmallSats destined for lunar orbit and beyond. This paper will present an overview of new service offerings the NASA Near Earth Network (NEN) is currently investigating and demonstrating. It will describe the benefits that new service offerings such as Multiple Spacecraft Per Aperture (MSPA), Ground-based Phased Array (GBPA) antennas, Ground-based Aperture Arrays, and Ground-based Antenna Arraying could provide to individual or formation flying SmallSats anywhere from low-earth orbit to the Sun-Earth Lagrange point orbits. It will also present potential implementation options for future demonstrations at the NASA Goddard Space Flight Center (GSFC) Wallops Flight Facility (WFF) as well as goals and objectives of such demonstrations

    Evaluation of chronic lymphocytic leukemia by oligonucleotide-based microarray analysis uncovers novel aberrations not detected by FISH or cytogenetic analysis

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    <p>Abstract</p> <p>Background</p> <p>Cytogenetic evaluation is a key component of the diagnosis and prognosis of chronic lymphocytic leukemia (CLL). We performed oligonucleotide-based comparative genomic hybridization microarray analysis on 34 samples with CLL and known abnormal karyotypes previously determined by cytogenetics and/or fluorescence <it>in situ </it>hybridization (FISH).</p> <p>Results</p> <p>Using a custom designed microarray that targets >1800 genes involved in hematologic disease and other malignancies, we identified additional cryptic aberrations and novel findings in 59% of cases. These included gains and losses of genes associated with cell cycle regulation, apoptosis and susceptibility loci on 3p21.31, 5q35.2q35.3, 10q23.31q23.33, 11q22.3, and 22q11.23.</p> <p>Conclusions</p> <p>Our results show that microarray analysis will detect known aberrations, including microscopic and cryptic alterations. In addition, novel genomic changes will be uncovered that may become important prognostic predictors or treatment targets for CLL in the future.</p

    The Vehicle, Spring 1993

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    1993 Commemorative Edition: Celebrating 35 Years Table of Contents The Vehicle Editors\u27 Lineagepage 5 Milestonespage 6 THE SIXTIES Coverspage 7 Editors\u27 Notespage 8 Sureness is Never - excerptDon Shepardsonpage 9 SophisticationBenjamin Polkpage 10 A SonnetMignon Stricklandpage 11 The Twenty-Third ChannelBen Polkpage 11 Opposite AttractionsC.E.M. (Christine McColl)page 12 John F. KennedyJoel E. Hendrickspage 13 The Girl on the White PonyLarry Gatespage 14 The TimesW.D.M. (William Moser)page 16 Home ThoughtsJane Careypage 17 1966Roger Zulaufpage 18 Nagging ThoughtJanet Andrewspage 18 THE SEVENTIES Coverspage 19 Editors\u27 Notespage 20 RevolutionsSteve Siegelpage 21 UntitledKristine Kirkhampage 23 The Arithmetic ProblemJanice Forbuspage 23 Willie Seeverson Threw a Worm at MeMary Pipekpage 24 a love poem (by approximation)Ted Baldwinpage 25 Night and Summer in Two WorldsBarry Smithpage 26 Story of a Teenage PickleTerry Louis Schultzpage 27 Danny Lonely, Danny WildDevin Brownpage 28 Always TomorrowMary McDanielpage 29 THE EIGHTIES Coverspage 31 Having ChildrenDevon Flesorpage 33 What is Unnatural Is Sometimes MagicAngelique Jenningspage 34 If My Father Were A Writer, He Would Still BuildAngelique Jenningspage 35 Photo AlbumPatrick Peterspage 36 Poet Born in Pearl HarborAngelique Jenningspage 37 The History of High School BasketballPatrick Peterspage 38 Banana BreadGail Bowerpage 39 Cover LetterBob Zordanipage 40 Home MoviesBob Zordanipage 41 MigrationPatrick Peterspage 42 THE NINETIES Ba, Ba, Black SheepVictoria Bennettpage 45 Daily LessonsJennifer Moropage 49 Folding My OwnLaurie Ann Malispage 51 About the Authorspage 53 Editors\u27 Notespage 56https://thekeep.eiu.edu/vehicle/1062/thumbnail.jp

    The Vehicle, Spring 1993

    Get PDF
    1993 Commemorative Edition: Celebrating 35 Years Table of Contents The Vehicle Editors\u27 Lineagepage 5 Milestonespage 6 THE SIXTIES Coverspage 7 Editors\u27 Notespage 8 Sureness is Never - excerptDon Shepardsonpage 9 SophisticationBenjamin Polkpage 10 A SonnetMignon Stricklandpage 11 The Twenty-Third ChannelBen Polkpage 11 Opposite AttractionsC.E.M. (Christine McColl)page 12 John F. KennedyJoel E. Hendrickspage 13 The Girl on the White PonyLarry Gatespage 14 The TimesW.D.M. (William Moser)page 16 Home ThoughtsJane Careypage 17 1966Roger Zulaufpage 18 Nagging ThoughtJanet Andrewspage 18 THE SEVENTIES Coverspage 19 Editors\u27 Notespage 20 RevolutionsSteve Siegelpage 21 UntitledKristine Kirkhampage 23 The Arithmetic ProblemJanice Forbuspage 23 Willie Seeverson Threw a Worm at MeMary Pipekpage 24 a love poem (by approximation)Ted Baldwinpage 25 Night and Summer in Two WorldsBarry Smithpage 26 Story of a Teenage PickleTerry Louis Schultzpage 27 Danny Lonely, Danny WildDevin Brownpage 28 Always TomorrowMary McDanielpage 29 THE EIGHTIES Coverspage 31 Having ChildrenDevon Flesorpage 33 What is Unnatural Is Sometimes MagicAngelique Jenningspage 34 If My Father Were A Writer, He Would Still BuildAngelique Jenningspage 35 Photo AlbumPatrick Peterspage 36 Poet Born in Pearl HarborAngelique Jenningspage 37 The History of High School BasketballPatrick Peterspage 38 Banana BreadGail Bowerpage 39 Cover LetterBob Zordanipage 40 Home MoviesBob Zordanipage 41 MigrationPatrick Peterspage 42 THE NINETIES Ba, Ba, Black SheepVictoria Bennettpage 45 Daily LessonsJennifer Moropage 49 Folding My OwnLaurie Ann Malispage 51 About the Authorspage 53 Editors\u27 Notespage 56https://thekeep.eiu.edu/vehicle/1062/thumbnail.jp

    Telomere length, antioxidant status and incidence of ischaemic heart disease in type 2 diabetes

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    BACKGROUND: Type 2 diabetes (T2D) is associated with an increased risk of ischaemic heart disease (IHD). An accelerated process of vascular ageing induced by an increased oxidative stress exposure is suggested as potential pathway accounting for this association. However, no studies have explored the relationship between markers of vascular ageing, measures of oxidative stress and risk of IHD in T2D. OBJECTIVES: To explore the association between plasma antioxidant status, marker of cellular ageing (leukocyte telomere length, LTL) and 10years risk of IHD in patients with T2D. METHODS: Between 2001 and 2002, 489 Caucasians subjects with T2D were enrolled at the diabetic clinic, University College London Hospital. Plasma total anti-oxidant status (TAOS) and LTL were measured by photometric microassay and RT-PCR, respectively. The incidence of IHD over 10years was determined through linkage with the national clinical audit of acute coronary syndrome in UK. RESULTS: At baseline, TAOS was associated with LTL (age adjusted: r=0.106, p=0.024). After 10years, 61 patients developed IHD. Lower TAOS and shorter LTL at baseline predicted an increased IHD risk at follow-up (age adjusted: p=0.033 and p=0.040, respectively). These associations were independent of age, gender, cardiovascular risk factors, circulating levels of CRP and medication differences. CONCLUSIONS: Reduced TAOS and short LTL are interrelated pathways which predict risk of IHD in patients with T2D. Our findings suggest that antioxidant defences are important to maintain telomere integrity, potentially reducing the progression of vascular ageing in patients with T2D
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