Quaternary and quinary modifications of eutectic superalloys strengthened by delta Ni3Cb lamellae and gamma prime Ni3Al precipitates

By means of a compositional and heat treatment optimization program based on the quaternary gamma/gamma prime-delta, a tantalum modified gamma/gamma prime-delta alloy with improved shear and creep strength combined with better cyclic oxidation resistance was identified. Quinary additions, quaternary adjustments, and heat treatment were investigated. The tantalum modified gamma/gamma prime-delta alloy possessed a slightly higher liquidus temperature and exhibited rupture strength exceeding NASA VIA by approximately three and one-half Larson-Miller parameters (C = 20) above 1000 C. Although improvements in longitudinal mechanical properties were achieved, the shear and transverse strength property goals of the program were not met and present a continuing challenge to the alloy metallurgist

Space telescope phase B definition study. Volume 2A: Science instruments, f24 field camera

The analysis and design of the F/24 field camera for the space telescope are discussed. The camera was designed for application to the radial bay of the optical telescope assembly and has an on axis field of view of 3 arc-minutes by 3 arc-minutes

Mission design for a ballistic slow flyby Comet Encke 1980

Preliminary mission analyses for a proposed 1980 slow flyby (7-9 km/s) of comet Encke are presented. Among the topics covered are science objectives, Encke's physical activity and ephemeris accuracy, trajectory and launch-window analysis, terminal guidance, and spacecraft concepts. The nominal mission plan calls for a near-perihelion intercept with two spacecraft launched on a single launch vehicle. Both spacecraft will arrive at the same time, one passing within 500 km from Encke's nucleus on its sunward side, the other cutting through the tail region. By applying a small propulsive correction about three weeks after the encounter, it is possible to retarget both spacecraft for a second Encke intercept in 1984. The potential science return from the ballistic slow flyby is compared with other proposed mission modes for the 1980 Encke flyby mission, including the widely advocated slow flyby using solar-electric propulsion. It is shown that the ballistic slow flyby is superior in every respect

Towards using NMR to screen for spoiled tomatoes stored in 1,000 L, aseptically sealed, metal-lined totes.

Nuclear magnetic resonance (NMR) spectroscopy is used to track factory relevant tomato paste spoilage. It was found that spoilage in tomato paste test samples leads to longer spin lattice relaxation times T1 using a conventional low magnetic field NMR system. The increase in T1 value for contaminated samples over a five day room temperature exposure period prompted the work to be extended to the study of industry standard, 1,000 L, non-ferrous, metal-lined totes. NMR signals and T1 values were recovered from a large format container with a single-sided NMR sensor. The results of this work suggest that a handheld NMR device can be used to study tomato paste spoilage in factory process environments

Oxidative stress in pre-eclampsia; have we been looking in the wrong place?

Pre-eclampsia is a disorder of late pregnancy. It is a major cause of maternal and perinatal morbidity and mortality, accounting for nearly 18% of all maternal deaths worldwide; an estimated 77,000 maternal deaths per year [1]. Poor placentation is considered to be an initial cause of the placental ischemia [2]. Placental ischemia in turn gives rise to oxidative stress in the placenta and leads to shedding of syncytiotrophoblast debris into the maternal circulation provoking a systemic maternal inflammatory response and release of sFLT and sENG causing maternal vascular endothelial dysfunction. The ubiquitous nature of the maternal vascular endothelium accounts for the diverse multi-system nature of pre-eclampsia. Currently there is no treatment for pre-eclampsia except delivery of the placenta and the baby, with the attendant risk of iatrogenic prematurity and significant neonatal morbidity and mortality. As a result, intensive research endeavours have focused on defining the molecular mechanisms of pre-eclampsia and the identification of new pre-symptomatic biomarkers of the condition. This review focuses on the role of elevated oxidative stress in the pathology of pre-eclampsia and potential therapeutic agents targeting oxidative stress that may prevent or ameliorate this disorder

Chemical abundances and winds of massive stars in M31: a B-type supergiant and a WC star in OB10

We present high quality spectroscopic data for two massive stars in the OB10 association of M31, OB10-64 (B0Ia) and OB10-WR1 (WC6). Medium resolution spectra of both stars were obtained using the ISIS spectrograph on the William Hershel Telescope. This is supplemented with HST-STIS UV spectroscopy and KeckI HIRES data for OB10-64. A non-LTE model atmosphere and abundance analysis for OB10-64 is presented indicating that this star has similar photospheric CNO, Mg and Si abundances as solar neighbourhood massive stars. A wind analysis of this early B-type supergiant reveals a mass-loss rate of M_dot=1.6x10^-6 M_solar/yr,and v_infty=1650 km/s. The corresponding wind momentum is in good agreement with the wind momentum -- luminosity relationship found for Galactic early B supergiants. Observations of OB10W-R1 are analysed using a non-LTE, line-blanketed code, to reveal approximate stellar parameters of log L/L_solar \~ 5.7, T~75 kK, v_infty ~ 3000 km/s, M_dot ~ 10^-4.3 M_solar/yr, adopting a clumped wind with a filling factor of 10%. Quantitative comparisons are made with the Galactic WC6 star HD92809 (WR23) revealing that OB10-WR1 is 0.4 dex more luminous, though it has a much lower C/He ratio (~0.1 versus 0.3 for HD92809). Our study represents the first detailed, chemical model atmosphere analysis for either a B-type supergiant or a WR star in Andromeda, and shows the potential of how such studies can provide new information on the chemical evolution of galaxies and the evolution of massive stars in the local Universe.Comment: 17 pages, 14 figures, MNRAS accepted version, some minor revision

Are food exposures obtained through commercial market panels representative of the general population? Implications for outbreak investigations

Current methods of control recruitment for case-control studies can be slow (a particular issue for outbreak investigations), resource-intensive and subject to a range of biases. Commercial market panels are a potential source of rapidly recruited controls. Our study evaluated food exposure data from these panel controls, compared with an established reference dataset. Market panel data were collected from two companies using retrospective internet-based surveys; these were compared with reference data from the National Diet and Nutrition Survey (NDNS). We used logistic regression to calculate adjusted odds ratios to compare exposure to each of the 71 food items between the market panel and NDNS participants. We compared 2103 panel controls with 2696 reference participants. Adjusted for socio-demographic factors, exposure to 90% of foods was statistically different between both panels and the reference data. However, these differences were likely to be of limited practical importance for 89% of Panel A foods and 79% of Panel B foods. Market panel food exposures were comparable with reference data for common food exposures but more likely to be different for uncommon exposures. This approach should be considered for outbreak investigation, in conjunction with other considerations such as population at risk, timeliness of response and study resources

Construction of an instrument for the measurement of educational philosophy

Thesis (M.Ed.)--Boston Universit