Ectoplasm & Superspace Integration Measure for 2D Supergravity with Four Spinorial Supercurrents

Building on a previous derivation of the local chiral projector for a two dimensional superspace with eight real supercharges, we provide the complete density projection formula required for locally supersymmetrical theories in this context. The derivation of this result is shown to be very efficient using techniques based on the Ectoplasmic construction of local measures in superspace.Comment: 18 pages, LaTeX; V2: minor changes, typos corrected, references added; V3: version to appear in J. Phys. A: Math. Theor., some comments and references added to address a referee reques

The Impact of the Introduction of Total Mesorectal Excision on Local Recurrence Rate and Survival in Rectal Cancer: Long-Term Results

Purpose: To investigate the influence of the introduction of total mesorectal excision (TME) on local recurrence rate and survival in patients with rectal cancer. Methods: A total of 171 consecutive patients underwent anterior or abdominoperineal resection for primary rectal cancer. When the TME technique was introduced, the clinical setting, including the surgeons, remained the same. Group 1 (1993-95, n=53) underwent conventional surgery and group 2 (1995-2001, n=118) underwent TME. All patients were followed for 7years or until death. Results: Between the two groups, no statistically significant differences were present with regards to patient-, treatment-, or tumor-related characteristics apart from the time point of radiotherapy. The total local recurrence rates were 11 of 53 (20.8%) in group 1 and 7 of 118 (5.9%) in group 2, and the rates of isolated local recurrences were 6 of 53 (11.3%) in group 1 and 2 of 118 (1.7%) in group 2. Both differences were highly statistically significant. The disease-free survival in groups 1 and 2 was 60.4 and 65.3% at 5years, and 58.5 and 65.3% at 7years, respectively. Excluding patients with synchronous or metachronous distant metastasis from the analysis, both the disease-free survival and the cancer-specific survival were statistically significantly better in group 2 than in group 1. No statistically significant difference between the two groups was detected regarding the overall survival. Conclusions: The introduction of TME led to an impressive reduction of the local recurrence rate. Survival is mainly determined by the occurrence of distant metastasis, but TME seems to improve survival in patients without systemic diseas

Indocyanine Green Nanoparticles : Are They Compelling for Cancer Treatment?

Indocyanine green (ICG) is a Food and Drug Administration\u2013approved near-infrared fluorescent dye, employed as an imaging agent for different clinical applications due to its attractive physicochemical properties, high sensitivity, and safety. However, free ICG suffers from some drawbacks, such as relatively short circulation half-life, concentration-dependent aggregation, and rapid clearance from the body, which would confine its feasible application in oncology. Here, we aim to discuss encapsulation of ICG within a nanoparticle formulation as a strategy to overcome some of its current limitations and to enlarge its possible applications in cancer diagnosis and treatment. Our purpose is to provide a short but exhaustive overview of clinical outcomes that these nanocomposites would provide, discussing opportunities, limitations, and possible impacts with regard to the main clinical needs in oncology

U-Pb zircon SHRIMP data from the Cana Brava layered complex: new constraints for the mafic-ultramafic intrusions of Northern Goiás, Brazil

The Cana Brava Complex is the northernmost and less-known layered intrusion of a discontinuous belt of mafic-ultramafic massifs within the Brasilia Belt, which also comprises the Niquelândia and Barro Alto complexes. Available geochronological determination by means of different systematics (K/Ar, Ar/Ar, Rb/Sr, Sm/Nd and U/Pb) provide a range of possible ages (time span from 3.9 Ga to 450 Ma), hence a precise and statistically reliable age for the Cana Brava Complex is still lacking. Also, preliminary isotopic and geochemical data of the Cana Brava Complex suggest a significant crustal contamination, which could have affected bulk-rock Sr and Nd systematics resulting in meaningless age determinations. In this paper, we present new U-Pb SHRIMP zircon analyses from four samples of different units of the Cana Brava Complex which suggest that the intrusion occurred during the Neoproterozoic, between 800 and 780 Ma, i.e. at the same age of Niquelândia. Discordant older 206Pb/238U ages are provided by inherited zircons, and match the age of the metamorphism of the encasing Palmeirópolis Sequence

Elastic geobarometry for anisotropic inclusions in cubic hosts

Mineral inclusions entrapped in other minerals may record the local stresses at the moment of their entrapment in the deep Earth. When rocks are exhumed to the surface of the Earth, residual stresses and strains may still be preserved in the inclusion. If measured and interpreted correctly through elastic geobarometry, they give us invaluable information on the pressures (P) and temperatures (T) of metamorphism. Current estimates of P and T of entrapment rely on simplified models that assumes that the inclusion is spherical and embedded in an infinite host, and that their elastic properties are isotropic. We report a new method for elastic geobarometry for anisotropic inclusions in quasi-isotropic hosts. The change of strain in the inclusion is modelled with the axial equations of state of the host and the inclusion. Their elastic interaction is accounted for by introducing a 4th rank tensor, the relaxation tensor, that can be evaluated numerically for any symmetry of the host and the inclusion and for any geometry of the system. This approach can be used to predict the residual strain/stress state developed in an inclusion after exhumation from known entrapment conditions, or to estimate the entrapment conditions from the residual strain measured in real inclusions. In general, anisotropic strain and stress states are developed in non-cubic mineral inclusions such as quartz and zircon, with deviatoric stresses typically limited to few kbars. For garnet hosts, the effect of the mutual crystallographic orientation between the host and the inclusion on the residual strain and stress is negligible when the inclusion is spherical and isolated. Assuming external hydrostatic conditions, our results suggest that the isotropic and the new anisotropic models give estimations of entrapment conditions within 2%

A metal-poor damped Ly-alpha system at redshift 6.4

We identify a strong Ly-alpha damping wing profile in the spectrum of the quasar P183+05 at z=6.4386. Given the detection of several narrow metal absorption lines at z=6.40392, the most likely explanation for the absorption profile is that it is due to a damped Ly-alpha system. However, in order to match the data a contribution of an intergalactic medium 5-38% neutral or additional weaker absorbers near the quasar is also required. The absorption system presented here is the most distant damped Ly-alpha system currently known. We estimate an HI column density ($10^{20.68\pm0.25}\,$cm$^{-2}$), metallicity ([O/H]$=-2.92\pm 0.32$), and relative chemical abundances of a system consistent with a low-mass galaxy during the first Gyr of the universe. This object is among the most metal-poor damped Ly-alpha systems known and, even though it is observed only ~850 Myr after the big bang, its relative abundances do not show signatures of chemical enrichment by Population III stars.Comment: Updated to match published versio

On 2D N=(4,4) superspace supergravity

We review some recent results obtained in studying superspace formulations of 2D N=(4,4) matter-coupled supergravity. For a superspace geometry described by the minimal supergravity multiplet, we first describe how to reduce to components the chiral integral by using ``ectoplasm'' superform techniques as in arXiv:0907.5264 and then we review the bi-projective superspace formalism introduced in arXiv:0911.2546. After that, we elaborate on the curved bi-projective formalism providing a new result: the solution of the covariant type-I twisted multiplet constraints in terms of a weight-(-1,-1) bi-projective superfield.Comment: 18 pages, LaTeX, Contribution to the proceedings of the International Workshop "Supersymmetries and Quantum Symmetries" (SQS'09), Dubna, July 29-August 3 200

Comparing the Cana Brava and Niquelândia complexes: large mafic-ultramafic intrusions in the lower crust and contamination processes

Mafic-ultramafic complexes offer a unique opportunity to study how intrusions of mantlederived melts growth into the deep crust and interact with the country rocks. The Cana Brava and Niquelândia complexes are two mafic-ultramafic bodies which outcrop within the Brasilia Belt (Goias, central Brazil) and that intruded the metavolcanicmetasedimentary sequences of Palmeiropolis and Indaianopolis during a Neoproterozoic continental rifting. The two complexes are parts, together with the Barro Alto complex, of a ~350 km NNE-trend belt of layered bodies which were exhumed during the Gondwana formation. New field, geochemical and isotopic data give new constraints on the model of growth of these complexes and the interactions between parent melts and the lower crust. Field evidences suggest that the complexes grow via multiple-melt intrusions under hyper- to subsolidus shear conditions. During the complex growth, the upper metavolcanic-metasedimentary sequence was delaminated and xenoliths were incorporated and deformed within the crystal mush. The increase of the 87Sr/86Sr(790) along the complex stratigraphy, coupled with a decrease of the εNd(790), provides evidences of strong crustal contamination by the embedded xenoliths. The enrichment in most incompatible elements (e.g. K, Ba and LREE) and hydrous phases (biotite and amphibole) in rocks containing more xenoliths supports also the crustal contamination. The almost linear trend of isotopic contamination suggests that this process involved all the magma colum, similarly to AFC. However, the increase abundance of incompatible elements and H2O contents toward xenoliths-rich bands provide for a local effect of contamination

Powerful Radio Sources in the Southern Sky. II. A Swift X-Ray Perspective

We recently constructed the G4Jy-3CRE, a catalog of extragalactic radio sources based on the GLEAM 4-Jy (G4Jy) sample, with the aim of increasing the number of powerful radio galaxies and quasars with similar selection criteria to those of the revised release of the Third Cambridge Catalog (3CR). The G4Jy-3CRE consists of a total of 264 radio sources mainly visible from the Southern Hemisphere. Here, we present an initial X-ray analysis of 89 G4Jy-3CRE radio sources with archival X-ray observations from the Neil Gehrels Swift Observatory. We reduced a total of 624 Swift observations, for about 0.9 Ms of integrated exposure time. We found X-ray counterparts for 59 radio sources belonging to the G4Jy-3CRE, nine of them showing extended X-ray emission. The remaining 30 sources do not show any X-ray emission associated with their radio cores. Our analysis demonstrates that X-ray snapshot observations, even if lacking uniform exposure times, as those carried out with Swift, allow us to (i) verify and/or refine the host galaxy identification; (ii) discover the extended X-ray emission around radio galaxies of the intracluster medium when harbored in galaxy clusters, as the case of G4Jy 1518 and G4Jy 1664; and (iii) detect X-ray radiation arising from their radio lobes, as for G4Jy 1863