85 research outputs found
Post-Thyroidectomy Hypocalcemia: Timing of Discharge Based on Serum Calcium Levels
Purpose: The study concerns about the evaluation of Calcium serum levels in patients who underwent
total thyroidectomy. Our previous experience underlined how patients who had levels
of serum Calcium more than 9 mg/dl at the first day after surgery, did not show Hypocalcemia
in the next days,so that this value could be considered a good cut-off for the decision of an
early discharge. With regards to this experience, the aim of our current study was to confirm
the effective feasibility of an early discharge based on the levels of serum Calcium at the first
post-operative day.
Patients and Methods: Our study included 102 consecutive patients (82 F; 20 M, age with a
range between 14-78 year sold, average 52.6) that were submitted to total thyroidectomy in the
years 2010 to 2014, performed by the same operator and all done with sutureless technique (Ligasure
precise©) We classify hypocalcemia, according to their normal range (8.6 to 10.4 mg/dl),
in mild (not less than 7.6 mg/dL), moderate (between 7.5 mg/dL and 7 mg/dL) and severe (less
than 7 mg/dL) We classified the normal range of serum Calcium between 8.6 mg/dl and 10.4
mg/dl. Patients that showed levels of serum Calcium under this limit (<8.6 mg/dl) were treated
with 6 fials of Gluconate Calcium 40 mEq in 500 ml of saline solution NaCl 0.9% i.v. (one per
day), until the return to the normal range. Patients who had serum Calcium levels more than 9
mg/dl at the first post-operative days, and did not have other complications, were discharged at
the same day and revaluated after 7 days.
Discussion and Conclusion: Moreover our study has been useful to confirm what we observed
in the previous experience, that levels of serum Calcium more than 9 mg/dl at the first postoperative
day can be considered a feasible cut-off to exclude the appearance of hypocalcaemia
in future.
Therefore, according to our results, we assume to propose an early discharge for the patients
who have serum Calcium levels more than 9 mg/dl, asking them to come back for controls one
week after discharge
Atrial electro-anatomical remodeling as a predictor of the success of circumferential pulmonary vein ablation for atrial fibrillation
The Role of Quantic Molecular Resonance (QMR) in the Treatment of Inferior Turbinate Hypertrophy (ITH): Our Experience With Long-Term Follow-Up in Allergic and Nonallergic Rhinitis Refractory to Medical Therapy. Preliminary Results.
Objective: The aim of this study was to assess the long-term effectiveness of quantic molecular resonance (QMR) in the treatment of inferior turbinate hypertrophy (ITH) in allergic and nonallergic rhinitis refractory to medical therapy. Methods: This study enrolled 281 patients, 160 males (56.9%) and 121 females (43.1%), mean age 37.8 ± 4.1 years, range 18 to 71. Fifty-four patients have been lost to follow up and have been therefore excluded from the final analysis. Based on skin prick test results, 69 patients were considered allergic (group A) and 158 nonallergic (group B). All subjects underwent before surgery (T0) and 3 (T1), 12 (T2), 24 (T3), and 36 months (T4) after QMR treatment to: 4-phase rhinomanometric examination, nasal endoscopy evaluation, and visual analogue scale to quantify the subjective feelings about nasal obstruction. Results: Subjective and objective parameters showed statistically significant improvement in both groups. Group B parameters not changed during follow-up, while group A showed significant worsening between T1 and subsequent assessments. T4 outcome indicates a better result in nonallergic patients. Conclusions: In accordance with the literature, our preliminary data validate QMR treatment as a successful therapeutic option for nasal obstruction due to ITH. Nonallergic patients had a very good T4 outcome. Allergic patients showed a worsening trend after 1 year probably due to other causes
Effects of PACAP and VIP on hyperglycemia-induced cell proliferation in murine microvascular endothelial cells
Periprocedural outcome in patients undergoing left atrial appendage occlusion with the Watchman FLX device: The ITALIAN-FLX registry
IntroductionThe Watchman FLX is a novel device for transcatheter left atrial appendage occlusion (LAAO) specifically designed to improve procedural performance in more complex anatomies with a better safety profile. Recently, small prospective non-randomized studies have shown good procedural success and safety compared with previous experiences. Results from large multicenter registries are needed to confirm the safety and efficacy of the Watchman FLX device in a real-world setting.MethodsItalian FLX registry is a retrospective, non-randomized, multicentric study across 25 investigational centers in Italy including consecutive patients undergoing LAAO with the Watchman FLX between March 2019 and September 2021 (N = 772). The primary efficacy outcome was the technical success of the LAAO procedure (peri-device flow ≤ 5 mm) as assessed by intra-procedural imaging. The peri-procedural safety outcome was defined as the occurrence of one of the following events within 7 days after the procedure or by hospital discharge: death, stroke, transient ischemic attack, major extracranial bleeding (BARC type 3 or 5), pericardial effusion with tamponade or device embolization.ResultsA total of 772 patients were enrolled. The mean age was 76 ± 8 with a mean CHA2DS2-VASc score of 4.1 ± 1.4 and a mean HAS-BLED score of 3.7 ± 1.1. Technical success was achieved in 772 (100%) patients with the first device implanted in 760 (98.4%) patients. A peri-procedural safety outcome event occurred in 21 patients (2.7%) with major extracranial bleeding being the most common (1.7%). No device embolization occurred. At discharge 459 patients (59.4%) were treated with dual antiplatelet therapy (DAPT).ConclusionsThe Italian FLX registry represents the largest multicenter retrospective real-world study reporting periprocedural outcome of LAAO with the Watchman FLX device, resulting in a procedural success rate of 100% and a low incidence of peri-procedural major adverse events (2.7%)
Five-year clinical outcomes in patients with diabetes mellitus treated with polymer-free sirolimus- and probucol-eluting stents versus second-generation zotarolimus-eluting stents: a subgroup analysis of a randomized controlled trial
Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia
Problemi di regolazione glicemica dopo ampia resezione pancreatica per carcinoma
Dottorato di ricerca in oncologia chirurgica dell'apparato digerente. 7. ciclo. A.a. 1991-95. Coordinatore G. RodolicoConsiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca Nazionale Centrale - P.za Cavalleggeri, 1, Florence / CNR - Consiglio Nazionale delle RichercheSIGLEITItal
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