Isostaticity of Constraints in Jammed Systems of Soft Frictionless Platonic Solids

The average number of constraints per particle $$ in mechanically stable systems of Platonic solids (except cubes) approaches the isostatic limit at the jamming point ($\rightarrow 12$), though average number of contacts are hypostatic. By introducing angular alignment metrics to classify the degree of constraint imposed by each contact, constraints are shown to arise as a direct result of local orientational order reflected in edge-face and face-face alignment angle distributions. With approximately one face-face contact per particle at jamming chain-like face-face clusters with finite extent form in these systems.Comment: 4 pages, 3 figures, 4 tabl

Ethics and Epidemiology Workshop Report: Towards Ethics-Informed Epidemiology and Epidemiology-Informed Ethics

Two key groups of researchers have worked in parallel to advance health equity—one on the descriptive component (those in public health sciences, e.g., epidemiologists) and one on the normative component (those in the humanities and social sciences, e.g., philosophers and ethicists). Yet a significant gulf exists between their respective research. Consequently, advances in thinking regarding the philosophical underpinnings and normative requirements of health equity have been largely divorced from the design of public health interventions that seek to reduce health inequities. As a consequence, public health interventions aiming to advance health equity may fail to target the most appropriate populations or the most ethically important health disparities and therefore likely fail to achieve the most ‘equitable’ health outcomes. At the same time, without empirically testing different philosophical criteria of health equity, philosophers will end up producing guidance for the design and implementation of public health interventions that may ultimately have undesirable (or less desirable) outcomes in practice. To discuss the contours of this challenge and possible avenues to address it, a meeting was held on December 5, 2022 at the University Club of Toronto with support from the Canadian Institutes of Health Research (CIHR), Public Health Ontario, Western University, and the University of Toronto. In this meeting report, we summarize the workshop proceedings, report key findings based on the expert contributions of meeting participants, and identify next steps

Comparative Efficacy of Novel Endolysins in Queso Fresco

Listeria monocytogenes is problematic for the manufacturing, storage, and consumption of ready-to-eat foods. This bacterium may cause listeriosis upon consumption often with deadly complications. Queso Fresco (QF), a pasteurized Hispanic-style fresh cheese (HSFC), has been shown to support the growth of L. monocytogenes. QF is the most widely produced and implicated HSFC in the U.S., representing a significant health hazard to at risk populations such as infants, pregnant women, elderly, and the immunocompromised. The objective of this research project is to evaluate the efficacy of ten novel antimicrobial endolysins in combatting L. monocytogenes contamination in a miniaturized lab-scale queso fresco model over a 28 day shelf life

Supporting Primary and Secondary Beginning Teachers Online: Key findings of the Education Alumni Support Project

During 2005, the Education Alumni Support Project (EdASP) (Maxwell, Smith, Baxter, Boyd, Harrington, Jenkins, Sargeant & Tamatea 2006) provided online support for University of New England (UNE) graduand, and later, graduate, teachers as they commenced their careers. The project was based on research which reported that many beginning teachers did not get the support they needed as permanent or contract workers, or, as casual, relief or support teachers, and that small scale trials had shown that online support could be effective. One third of beginning teachers who were alumni of UNE in 2004, reported they did not receive adequate or any mentoring. UNE web-based technologies provided the teachers and mentors with online environments for professional and social interaction, and resource sharing. We found that support was especially sought by the project participants in their first school term, and there were differences in the levels of online support sought by secondary and primary beginning teachers. The project raises implications for on-going systemic support for beginning teachers, the issue of transition from students to teachers, as well as questions about teacher education students’ preparation. This paper provides the key findings of the project. Detailed description of the project structure, data collection and data analysis are available in Maxwell et al. (2006)

A Comparative Analysis of Airline Pilots’ Approaches to Learning

This paper reports a study investigating approaches to learning (deep, surface, achieving) by airline pilots. Three hundred and forty-six respondents from five international airlines and an institute completed the Pilot Learning Process Questionnaire (PLPQ). The results showed a general tendency for surface scores to be substantially lower than deep and achieving scores, with greatest variability among the carriers on the achieving scale. The European carrier was implicated in all post hoc analyses conducted and one Pacific Rim carrier\u27s profile showed significant differences from other airlines. The results are discussed in terms of cultural, training/rewards, and tenure factors. Implications for pilot training and selection are noted

Reducing Health Inequities Through Intersectoral Action: Balancing Equity in Health With Equity for Other Social Goods

Abstract Significant attention has been devoted to developing intersectoral strategies to reduce health inequities; however, these strategies have largely neglected to consider how equity in health ought to be weighted and balanced with the pursuit of equity for other social goods (eg, education equity). Research in this domain is crucial, as the health sector’s pursuit of health equity may be at odds with policies in other sectors, which may consider the reduction of health inequities to be peripheral to, if not incompatible with, their own equity-related aims. It is therefore critical that intersectoral strategies to reduce health inequities be guided by a more general account of social justice that is capable of carefully balancing equity in health against the pursuit of equity in other sectors

Critiquing Protein Family Classification Models Using Sufficient Input Subsets.

In many application domains, neural networks are highly accurate and have been deployed at large scale. However, users often do not have good tools for understanding how these models arrive at their predictions. This has hindered adoption in fields such as the life and medical sciences, where researchers require that models base their decisions on underlying biological phenomena rather than peculiarities of the dataset. We propose a set of methods for critiquing deep learning models and demonstrate their application for protein family classification, a task for which high-accuracy models have considerable potential impact. Our methods extend the Sufficient Input Subsets (SIS) technique, which we use to identify subsets of features in each protein sequence that are alone sufficient for classification. Our suite of tools analyzes these subsets to shed light on the decision-making criteria employed by models trained on this task. These tools show that while deep models may perform classification for biologically relevant reasons, their behavior varies considerably across the choice of network architecture and parameter initialization. While the techniques that we develop are specific to the protein sequence classification task, the approach taken generalizes to a broad set of scientific contexts in which model interpretability is essential

\u3cem\u3eCatena\u3c/em\u3e-Poly[[Bis(α-Thenoyltrifluoroacetonato)Copper(II)]-μ-1,4-Di-4-Pyridyl-2,3-Diazabuta-1,3-Diene]

In the one-dimensional title polymer, [Cu(C8H4F3O2S)2(C12H10N4)]n or [Cu(L)2(tta)2] [tta is -thenoyltrifluoroacetonato and L is 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene], Cu2+ lies on a center of inversion. It is axially coordinated by two pyridyl N atoms from two different L ligands and equatorially coordinated by four O atoms from two chelating tta ligands. The ligand L propagates the one-dimensional chain structure by serving as a bridging ligand between two Cu octahedra via Cu-N coordinate bonds

The time resolution of the St. Petersburg paradox

A resolution of the St. Petersburg paradox is presented. In contrast to the standard resolution, utility is not required. Instead, the time-average performance of the lottery is computed. The final result can be phrased mathematically identically to Daniel Bernoulli's resolution, which uses logarithmic utility, but is derived using a conceptually different argument. The advantage of the time resolution is the elimination of arbitrary utility functions.Comment: 20 pages, 1 figur