14 research outputs found

    World Congress Integrative Medicine & Health 2017: Part one

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    Fitzpatrick skin phototype is an independent predictor of squamous cell carcinoma risk after solid organ transplantation

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    BackgroundSolid organ transplant recipients (OTR) are at an increased risk of developing squamous cell carcinoma (SCC) of the skin after transplantation. In predominantly white cohorts, Fitzpatrick skin type (FST) has been reported to be a risk factor for developing posttransplantation skin cancers.ObjectiveOur goal was to determine if FST is a statistically significant risk factor for the development of SCC after solid organ transplantation in a diverse US population of OTR.MethodsA cohort of OTR completed a questionnaire of demographic factors, transplant type, FST, and skin cancer history. Univariate and multivariate analyses were performed to determine the risk factors for development of SCC after transplantation.ResultsAs expected, male subjects had an increased risk for SCC compared with female subjects (P = .02), and those aged 50 years and older at the time of transplantation were more likely to develop SCC compared with those younger than 50 years (P < .001). The risk of SCC increased with each incremental decrease in FST, from FST VI to FST I (linear test for trend P < .001).LimitationsOur questionnaire did not ask specifically about immunosuppressive medications; instead, organ transplant category was used as a proxy for level of immunosuppression.ConclusionsFST, a patient-reported variable, is an independent risk factor for the development of SCC in OTR, and should be elicited from patients who have gone or will undergo organ transplantation

    Clinton\u27s health care reform : an assessment

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    A forum presented by the Public Policy Working Group, Case Western Reserve University, October 21, 1993. Participants: Robert H. Binstock, moderator; J.B. Silvers, Joyce J. Fitzpatrick, Charles A. Peck, Kenneth B. Frisof, Maxwell J. Mehlma

    Clinton\u27s health care reform : an assessment

    No full text
    A forum presented by the Public Policy Working Group, Case Western Reserve University, October 21, 1993. Participants: Robert H. Binstock, moderator; J.B. Silvers, Joyce J. Fitzpatrick, Charles A. Peck, Kenneth B. Frisof, Maxwell J. Mehlma

    Fitzpatrick skin phototype is an independent predictor of squamous cell carcinoma risk after solid organ transplantation

    No full text
    BACKGROUND: Solid organ transplant recipients are at an increased risk of developing squamous cell carcinoma of the skin after transplant. In predominantly Caucasian cohorts, Fitzpatrick skin type (FST) has been reported to be a risk factor for developing post-transplant skin cancers. OBJECTIVE: Our goal was to determine if Fitzpatrick skin type is a statistically significant risk factor for the development of squamous cell carcinomas after solid organ transplant in a diverse US population of transplant recipients. METHODS: A cohort of transplant recipients completed a questionnaire of demographic factors, transplant type, Fitzpatrick skin type and skin cancer history. Univariate and multivariate analysis was performed to determine the risk factors for development of squamous cell carcinoma after transplant. RESULTS: As expected, male subjects had an increased risk for SCC compared to females (p=0.02), and subjects age 50 and over at the time of transplantation were more likely to develop SCC compared to those under 50 (p<0.001). The risk of SCC increased with each incremental decrease in Fitzpatrick skin type, from FST VI to FST I (linear test for trend p<0.001). LIMITATIONS: Our questionnaire did not ask specifically about immunosuppressive medications; instead, organ transplant category was used as a proxy for level of immunosuppression. CONCLUSIONS: Fitzpatrick skin type, a patient-reported variable, is an independent risk factor for the development of SCC in organ transplant recipients, and should be elicited from patients who have gone or will undergo organ transplantation
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