Chelators influenced synthesis of chitosan–carboxymethyl cellulose microparticles for controlled drug delivery

Abstract In this study, polyphenolic curcumin is entrapped within microcomposites made of biopolymers chitosan (CS) and carboxymethyl cellulose (CMC) formulated by ionic gelation method. Here, different concentrations of two chelating agents, barium chloride and sodium tripolyphosphate, are used to make microcomposites. Thus, the synthesized microparticles were characterized by FTIR, and their surface morphology was studied by SEM. Drug encapsulation efficiency and the drug release kinetics of CS–CMC composites are also studied. The produced microcomposites were used to study antibacterial activity in vitro

A meta-analysis of Geogebra software decade of assisted mathematics learning : what to learn and where to go?

Today, hundreds of studies on mathematics learning have been found in various literature, supported by the use of GeoGebra software. This meta-analysis aims to determine the overall effect of using GeoGebra software and the extent to which study characteristics moderate the study effect sizes to consider the implications later. This study analyzed 36 effect sizes from 29 primary studies identified from ERIC documents, Sage Publishing, Google Scholar, and repositories from 2010 to 2020, and a total of 2111 students. In order to support calculation accuracy, a Comprehensive Meta-analysis (CMA) software was used. The effect size is determined using the Hedges equation, with an acceptable confidence level of 95%. It is known that the overall effect size of using GeoGebra software on the mathematical abilities of students is 0.96 based on the estimation of the random-effect model, and the standard error is 0.08. These findings indicate that, on average, students exposed to GeoGebra-based learning outperformed math abilities, which was initially equivalent to 82% of students in traditional classrooms. This study considers the five characteristics of the study. It showed that the GeoGebra software used was more effective in sample conditions less than or equal to 30. Providing classrooms with sufficient numbers of computers allowed students to use them individually, which was necessary to achieve a higher level of effectiveness. GeoGebra software is more effective when the treatment duration is set to less than or equal to four weeks. These findings help educators consider the characteristics of studies that moderate effect sizes using the GeoGebra software in the future

PROFIL KOMUNIKASI MATEMATIK TERTULIS CALON GURU MATEMATIKA DENGAN TINGKAT KECEMASAN MATEMATIKA TINGGI DALAM PEMBUKTIAN MATEMATIKA

Penelitian ini mengekplorasi proses komunikasi matematik tertulis calon guru matematika dalam pembuktian matematika pada subjek dengan tingkat kecemasan matematika tinggi. Penelitian kualitatif ini melibatkan 69 orang mahasiswa. Dari 69 mahasiswa tersebut dipilih satu orang mahasiswa dengan kemampuan matematika sedang dan tingkat kecemasan matematika tinggi sebagai subjek penelitian. Berdasarkan hasil analisis terhadap tugas yang dikerjakan dan interview mendalam ditemukan bahwa aktivitas komunikasi matematik yang muncul dalam pembuktian adalah: menjelaskan apa yang dipahami dari soal, menjelaskan metode yang akan digunakan, menyajikan ide dalam bentuk gambar dan simbol, menyatakan kembali ide dalam bentuk lain yang lebih sesuai, menjelaskan ide, mengemukakan argumen, menyajikan langkah-langkah penyelesaian, menjelaskan ide, dan menegaskan hasil yang diperoleh. Hasil analisis memperlihatkan bahwa hampir pada setiap aktivitas komunikasi matematika, subjek tidak dapat menjelaskannya ide-idenya secara sistematis, logis, jelas, dan benar karena subjek gerogi dan tidak fokus pada pekerjaannya

Pengaruh Biochar dan Residunya serta Umur Defoliasi Daun Jagung terhadap Keuntungan Hasil Jagung dan Beberapa Jenis Kacang Tipe Tegak Secara Salome di Lahan Kering

The island of Timor with a dry tropical climate causes the emergence of a variety of local wisdom as a form of adaptation to environmental conditions. In West Timor, farmers use local knowledge as part of their ancestral heritage in the traditional farming system to improve the food security of family households. One form of local wisdom is a land and crop management system in which several types of food plants are planted simultaneously at the same planting hole (Salome). This study aims to prove the presence of biochar effects and residues as well as the age of defoliation on the results of corn in intercrops of Salome with several types of beans in dry land and to obtain suitable types of bean plants that are intercropped in Salome with corn. This research was conducted in July 2018 until July 2019 in the experimental garden of the Faculty of Agriculture, Timor University, Sasi village, Kefamenanu City District, TTU Regency. This research was conducted in two stages of planting, namely stage I, namely: planting in July to November 2018. Phase II was planting carried out in November 2018 to March 2019. This study used a 2 x 3 x 3 factorial randomized block design with 3 replications + corn monoculture and bean monoculture. The first factor is the use of biochar which consists of 2 levels, namely without biochar and the use of Biochar. The second factor is the age of corn dawn defoliation consisting of 3 levels, namely without defoliation, defoliation age 35 days after planting, defoliation age is 75 HST. The third factor is the type of upright type local beans consisting of 3 levels, namely: Vigna radiata L., Vigna umbellata L., Phaseolus vulgaris L., so there are 18 combinations. The results of the first phase of the research showed that the highest seed weight of corn produced a combination of treatment without biochar with defoliation age of 35 hst corn leaves in the monoculture system while in intercropping system produced by combination of biochar treatment, the defoliation age of 35 hst of corn leaves in the type of Vigna radiata L., The results of the second phase of the study showed that the combined treatment of using biochar residue, the defoliation age of 75 hst corn leaves produced the highest weight of corn seeds which were planted with intercropping system with mung bean types. The results of the first phase of the research showed that the highest seed weight of the bean plant was produced by a combination of treatments without biochar with type bean Phaseolus vulgaris L. in the monoculture system, whereas the intercropping system was produced by a combination of the use of biochar treatment without defoliation of corn leaves with the type of Phaseolus vulgaris L. beans, The results of the second phase of the study showed that the combination of the treatment of use without biochar residue, the age of defoliation of 35 HST corn leaves with the highest type of green beans in the intercropping system. Corn yield in the Salome intercropping system at the beginning of the use of biochar has decreased compared to control but has increased again when using biochar residue, the defoliation age of 35 hst corn leaves is better than without defoliation, all types of beans are suitable for planting with the Salome intercropping system. The types of Vigna radiata L. and Vigna umbellata L. are more suitable to be planted with the Salome intercropping system with corn at the beginning of biochar and pasa use when using biochar residues.Masyarakat petani di wilayah Timor Barat kerap menggunakan pengetahuan lokal sebagai bagian dari warisan leluhur dalam sistem pertanian tradisional untuk meningkatkan ketahanan pangan rumah tangga keluarga, menggunakan sistem pengelolaan tanah dan tanaman, yang mana beberapa jenis tanaman pangan ditanam secara bersamaan waktu dalam satu lubang tanam yang sama (Salome). Penelitian ini bertujuan untuk membuktikan adanya efek biochar dan residunya serta umur defoliasi terhadap hasil Jagung dalam tumpangsari salome dengan beberapa jenis kacang di lahan kering dan untuk memperoleh jenis tanaman kacang yang cocok ditumpangsarikan secara salome dengan Jagung. Penelitian ini dilaksanakan pada bulan Juli 2018 sampai Juli 2019 di kebun percobaan Fakultas Pertanian, Universitas Timor, Kelurahan Sasi, Kecamatan Kota Kefamenanu, Kabupaten TTU. Penelitian ini dilaksanakan dalam tiga tahap penanaman yaitu tahap I: penanaman pada bulan Juli sampai November 2018. Tahap II: penanaman pada bulan November 2018 sampai Maret 2019. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) Faktorial 2 x 3 x 3 dengan 3 kali ulangan + monokultur jagung dan monokultur kacang. Faktor pertama: penggunaan biochar yang terdiri dari 2 aras yaitu tanpa biochar dan penggunaan biochar. Faktor kedua: umur defoliasi daun Jagung yang terdiri dari 3 aras yaitu tanpa defoliasi , Umur defoliasi 35 Hari Setelah Tanam, Umur defoliasi 75 HST. Faktor ketiga: jenis Kacang lokal tipe tegak yang terdiri dari 3 aras yaitu: Vigna radiata L., Vigna umbellata L., Phaseolus vulgaris L., sehingga terdapat 18 kombinasi. Hasil penelitian tahap I menunjukkan bahwa Berat biji tanaman jagung tertinggi dihasilkan kombinasi perlakuan tanpa biochar dengan umur defoliasi daun Jagung 35 hst pada sistem monokultur sedangkan pada sistem tumpang sari dihasilkan oleh kombinasi perlakuan biochar, umur defoliasi daun Jagung 35 hst pada jenis kacang Vigna radiata L., Hasil penelitian tahap II menunjukkan bahwa bahwa kombinasi perlakuan penggunaan residu biochar, umur defoliasi daun jagung 75 hst menghasilkan berat biji Jagung tertinggi yang ditanam dengan sistem tumpangsari dengan jenis kacang hijau. Hasil penelitian tahap I menunjukkan bahwa Berat biji tanaman kacang tertinggi dihasilkan oleh kombinasi perlakuan tanpa biochar dengan jenis kacang Phaseolus vulgaris L. pada sistem monokultur, sedangkan pada sistem tumpangsari dihasilkan oleh kombinasi perlakuan penggunaan biochar tanpa defoliasi daun Jagung dengan jenis kacang Phaseolus vulgaris L. Hasil penelitian tahap II menunjukkan bahwa bahwa kombinasi perlakuan penggunaan tanpa residu biochar, umur defoliasi daun Jagung 35 hst dengan jenis kacang hijau paling tinggi pada sistem tanam tumpangsari. Hasil Jagung pada sistem tumpangsari salome diawal penggunaan biochar mengalami penurunan dibandingkan kontrol tetapi meningkat kembali pada saat penggunaan residu biochar, umur defoliasi daun Jagung 35 hst lebih baik dibandingkan tanpa defoliasi, semua jenis kacang cocok untuk ditaman dengan sistem tumpangsari salome. Jenis kacang Vigna radiata L. dan Vigna umbellata L. lebih cocok ditanam dengan sistem tumpangsari salome dengan Jagung pada awal penggunaan biochar maupun pasa saat penggunaan residu biochar

Grec 37

BIBLE. Veteris Testamenti partesBIBLE. Veteris Testamenti partes. ExcerptaBIBLE. Eclogæ seu excerpta e BibliisMAXIMUS (S.). Capita de charitateNumérisation effectuée à partir d'un document de substitution.(1) Excerpta e Proverbiis Salomonis : Κρεῖσσον ψωμός... ; — (13) Disputatio philosophi cujusdam in Arii gratiam, ex actis Nicæni concilii : Καὶ εἶπεν ὁ θεός... ; — (45) Excerpta e Bibliis et historiæ Constantinopolitanæ scriptoribus : Πρὸ πάντων καὶ σὺν πᾶσι... ; — (264) S. Maximi capita de charitat

Grec 1099

MAXIMUS (S.). Capita theologica, de virtute et vitioNumérisation effectuée à partir d'un document de substitution.S. Maximi capita theologica et œconomica quingentaFontebl.-Reg. 2922

Grec 1097

MAXIMUS (S.). EpistolæMAXIMUS (S.). MystagogiaMAXIMUS (S.). Orationis dominicæ brevis expositioMAXIMUS (S.). Expositio Psalmi LIXMAXIMUS (S.). Scholia in S. Dionysium AreopagitamMAXIMUS (S.). Scholia in S. Gregorium NazianzenumNumérisation effectuée à partir d'un document de substitution.(2) S. Maximi mystagogia ; — (31) orationis dominicæ brevis expositio ; — (48) commentarius allegoricus in Psalmum LIX ; — (55) epistolæ variæ XLII ; — (195 v°) quæstiones in SS. Dionysium Areopagitam et Gregorium NazianzenumMedic.-Reg. 2944

Medicinal cannabis for the treatment of anxiety disorders.

BACKGROUND Anxiety is second most common reason for medicinal cannabis prescription in Australia and is being treated with both Δ9-tetrahydrocannabinol (THC)-containing and cannabidiol (CBD)-dominant products. OBJECTIVE The aim of this article is to summarise recent advances in the understanding of medicinal cannabis in treating anxiety and recent trends in prescribing. DISCUSSION Clinical trials and laboratory studies provide evidence of anxiolytic effects of CBD in healthy volunteers and clinical populations, although current evidence is insufficient to support CBD as a first-line treatment. The evidence regarding the use of THC-dominant products for anxiety is ambiguous, with exacerbation of anxiety in some individuals and relief in others. Caution is required as THC can impair driving and cognitive function. Despite the lack of robust supportive evidence, prescription of medicinal cannabis products for anxiety is increasing rapidly, while illicit cannabis is widely used in the community to self-medicate anxiety. Approximately 17% of current prescriptions for anxiety are for CBD- dominant liquid products (oils), wafers and capsules, while the remainder are for THC-containing liquid products (33%) and herbal cannabis for vaporisation (50%). Medical practitioners should carefully consider potential risks and benefits when prescribing medicinal cannabis for anxiety disorders and should 'start low and go slow'