Software para decodificación y análisis de archivos binarios en computadoras navales

En el presente trabajo se detalla el diseño de un software de decodificación de archivos y análisis de grabaciones de eventos navales. Originalmente, las embarcaciones contaban con un programa operativo de características similares, que se ejecutaba sobre las computadoras de 24 bits de abordo. La única interfaz que se disponía era una terminal tipo teletipo donde el operador insertaba comandos y se imprimían los resultados sobre un papel, el cual se utilizaba posteriormente para analizar los resultados del evento naval realizado. Debido a sus múltiples defectos y problemas, se decidió realizar una reingeniería del mismo para poder sustituirlo con un software que se ejecute sobre una PC de uso comercial, brindándole al usuario mayores herramientas y facilidades a través de las tecnologías disponibles en la actualidad.XV Workshop Ingeniería de Software (WIS)Red de Universidades con Carreras en Informática (RedUNCI

Software para decodificación y análisis de archivos binarios en computadoras navales

En el presente trabajo se detalla el diseño de un software de decodificación de archivos y análisis de grabaciones de eventos navales. Originalmente, las embarcaciones contaban con un programa operativo de características similares, que se ejecutaba sobre las computadoras de 24 bits de abordo. La única interfaz que se disponía era una terminal tipo teletipo donde el operador insertaba comandos y se imprimían los resultados sobre un papel, el cual se utilizaba posteriormente para analizar los resultados del evento naval realizado. Debido a sus múltiples defectos y problemas, se decidió realizar una reingeniería del mismo para poder sustituirlo con un software que se ejecute sobre una PC de uso comercial, brindándole al usuario mayores herramientas y facilidades a través de las tecnologías disponibles en la actualidad.XV Workshop Ingeniería de Software (WIS)Red de Universidades con Carreras en Informática (RedUNCI

Software para decodificación y análisis de archivos binarios en computadoras navales

En el presente trabajo se detalla el diseño de un software de decodificación de archivos y análisis de grabaciones de eventos navales. Originalmente, las embarcaciones contaban con un programa operativo de características similares, que se ejecutaba sobre las computadoras de 24 bits de abordo. La única interfaz que se disponía era una terminal tipo teletipo donde el operador insertaba comandos y se imprimían los resultados sobre un papel, el cual se utilizaba posteriormente para analizar los resultados del evento naval realizado. Debido a sus múltiples defectos y problemas, se decidió realizar una reingeniería del mismo para poder sustituirlo con un software que se ejecute sobre una PC de uso comercial, brindándole al usuario mayores herramientas y facilidades a través de las tecnologías disponibles en la actualidad.XV Workshop Ingeniería de Software (WIS)Red de Universidades con Carreras en Informática (RedUNCI

Sistema de monitoreo continuo de niveles de densidad de potencia electromagnética presentes en el medio ambiente

En últimos años el crecimientos de los sistemas inalambricos a puesto de manifiesto la necesidad de desarrollar herramientas tecnológicas que permitan definir políticas de planificación y control que protejan a la población de la energía electromagnética presente en el ambiente. En el presente proyecto se pretende desarrollar un sistema de monitoreo de la densidad de potencia irradiada por las diversas fuentes emisoras, empleando para su estudio a la Descomposición Wavelet Packet (WPD) basada en la Transformada Wavelet Discreta (DWT) para segmentar y detectar las anomalías. Su procesado posterior se hará mediante periodograma, Transformada Discreta de Fourier (DFT) empleando el algoritmo para realizar la Transformada Rápida de Fourier (FFT) o la Transformada Z Chirp (CZT). La primera etapa de este proyecto será depurar el desarrollo del conjunto SDR- Computadora (el cual fue publicado en el catálogo como Producto Innovador con el Nº 18471 de la Undécima Edición del Concurso Nacional de Innovaciones INNOVAR 2015) y el sistema de análisis y comparación con valores normalizados. La segunda etapa sería depurar y robustecer el análisis de la señal adquirida y clasificada por la WPD mediante periodograma, FFT o CZT. La tercer etapa sería la construcción de un prototipo para el montaje en campo de forma de poder realizar las pruebas correspondientes.Eje: Procesamiento de Señales y Sistemas de Tiempo Real.Red de Universidades con Carreras en Informática (RedUNCI

Resilience management guidelines for critical infrastructures, translating resilience theory into practical and useful interventions

Resilience goes beyond safety and risk management encompassing the ability of organisations to proactively adapt to expected and unexpected situations (crisis, opportunities and changes). The literature on resilience is overwhelming, our systematic literature survey identified 300 different definitions on resilience, diverse developments. Hence, there is a need to translate this fragmented body of knowledge into consolidated practical solutions. The purpose of this paper is to introduce the final version of resilience management guidelines produced in the H2020 DARWIN project. Through a multidisciplinary approach, involving experts in the field of resilience, crisis and risk management and service providers in the Air Traffic Management, healthcare domains as well as representatives from other domains, the DARWIN project has produced evolving resilience management guidelines (DRMG). These guidelines are not prescriptive. Instead they enable organizations to have a critical view on their own crisis management activities. The DRMG are available in different formats for easy usage and maintenance to avoid them being dust-collectors on a shelf. In this way, organizations can adapt, adopt and integrate the guidelines into their own existing management practices and procedures. Through an iterative development process involving academia and practitioners, the guidelines are constructed around Capability Cards (CCs). The evaluation in pilot exercises and other activities involved 247 practitioners from 22 countries explored the possibility to adapt the CCs to the Healthcare and Air Traffic Management domains. It also consider the feasibility of generalizing them to other Critical Infrastructure domains. Our achievement is the current version of guidelines proposing practical interventions that end-users find useful. This paper represents and invitation to explore the content of the guidelines, to encourage its use and further developments of the resilience management

Analysis of KIT, SCF, and Initial Screening of SLUG in Patients with Piebaldism

n/

Visão de massa

O futebol é o esporte mais praticado no mundo. Sabedor disso a mídia tende a massificá-lo, pois ele está inserido em muitas culturas, o que facilita o acesso das grandes empresas e o marketing dos seus produtos... O que as mídias propiciam, num primeiro momento, é um grande mosaico sem estrutura lógica aparente, composto de informações desconexas, em geral descontextualizadas e recebidas individualmente, não instaurando portanto, um verdadeiro processo de comunicação. (BETTI,2003,p.93) xxx(livro)259.  Desde seu início o futebol teve um imenso empurrão das mídias, por ele ser um dos únicos de sua época a ser jogado com os pés, logo caiu no gosto popular por ser algo diferente de tudo que já existia. Por causa dessa força popular que se criou, vários políticos começaram a usar isso a seu favor, investindo em times de massa para autopromoção, o futebol tem alto relevância no cunho histórico-político, e até foi capaz de pausar guerras para que todos pudessem assistir partidas.&nbsp

A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body

BACKGROUND: Carbon dioxide (CO(2)) therapy refers to the transcutaneous administration of CO(2) for therapeutic purposes. This effect has been explained by an increase in the pressure of O(2) in tissues known as the Bohr effect. However, there have been no reports investigating the oxygen dissociation of haemoglobin (Hb) during transcutaneous application of CO(2)in vivo. In this study, we investigate whether the Bohr effect is caused by transcutaneous application of CO2 in human living body. METHODS: We used a novel system for transcutaneous application of CO(2) using pure CO(2) gas, hydrogel, and a plastic adaptor. The validity of the CO(2) hydrogel was confirmed in vitro using a measuring device for transcutaneous CO(2) absorption using rat skin. Next, we measured the pH change in the human triceps surae muscle during transcutaneous application of CO(2) using phosphorus-31 magnetic resonance spectroscopy ((31)P-MRS) in vivo. In addition, oxy- and deoxy-Hb concentrations were measured with near-infrared spectroscopy in the human arm with occulted blood flow to investigate O2 dissociation from Hb caused by transcutaneous application of CO(2). RESULTS: The rat skin experiment showed that CO(2) hydrogel enhanced CO(2) gas permeation through the rat skin. The intracellular pH of the triceps surae muscle decreased significantly 10 min. after transcutaneous application of CO(2). The NIRS data show the oxy-Hb concentration decreased significantly 4 min. after CO(2) application, and deoxy-Hb concentration increased significantly 2 min. after CO(2) application in the CO(2)-applied group compared to the control group. Oxy-Hb concentration significantly decreased while deoxy-Hb concentration significantly increased after transcutaneous CO(2) application. CONCLUSIONS: Our novel transcutaneous CO(2) application facilitated an O(2) dissociation from Hb in the human body, thus providing evidence of the Bohr effect in vivo

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure &lt; 100 mmHg (n = 1127), estimated glomerular filtration rate &lt; 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation