1,202 research outputs found
Simulation of Shaking Table Tests to Study Soil-Structure Interaction by Means of Two Different Constitutive Models
The paper presents the main results of a FEM 3-D model reproducing a physical model subjected to shaking table tests. The tests, performed at the EERC laboratory of Bristol University, have been simulated by means of a new numerical model based on a recent constitutive model characterized by isotropic and kinematic hardening and devoted to granular soil. The shaking table tests have been performed using: a six-degree of freedom shaking table; a shear-stack; a scaled one-storey steel frame; the Leigthon Buzzard Sand. The tests have been characterized by 11 shaking runs. As regards the 3-D numerical modeling, the linear elastic material has been considered for the structure, instead the soil has been modeled both with a cap-hardening Drucker-Prager model, often implemented in commercial codes, and with the above mentioned new constitutive model, implemented in the utilized FEM code by the Research Group of Catania University. Thanks to the great quantity of experimental data, the power of the proposed numerical model in simulation/prediction of dynamic soil-structure interaction can be verified and compared with the capability of other numerical models based on simpler constitutive models
Experimental, Theoretical and Numerical Evaluation of the Stiffness of a Soil-Foundation Model by Shaking-Table Test
A well-controlled test was carried out on a Leighton Buzzard sand-shallow foundation system by means of the six-degree-of-freedom shaking table available at the University of Bristol. The foundation consists of a concrete block located into a flexible shear-stack (Taylor et al., 1994) filled up to 1.00 m with the sand. During the test the block was subjected to a centered vertical load and to one direction sine dwell-type acceleration applied at the base of the shear stack. The static and dynamic sand properties were evaluated through different laboratory tests, among them resonant column tests, cyclic and monotonic loading torsional shear tests were performed (Mazzarella, 1999). A comprehensive network of accelerometers and displacement transducers was used to check the static and dynamic soil-foundation interaction (Maugeri et al., 1999a). The impedance functions (Gazetas, 1991) were evaluated and then compared with the experimental results. Finally, the experimental results were compared with the numerical ones obtained by means of a FEM code (Massimino, 1999) developed at the University of Catania
Screening and identification of cellulase producing yeast-like microorganisms from Brazilian biomes
The main goals of the present study included the screening and identification of cellulase producing wild yeasts, isolated from samples collected from different Brazilian biomes. They were selected according to their capabilities of degrading carboxymethyl cellulose (CMC) and micro-crystalline cellulose (SERVACEL®), as single carbon sources in solid medium. After the step of solid medium selection, yeast cells were grown in liquid medium containing cellulose (SERVACEL®); in shake flasks at temperature of 30°C and 150 rpm agitation for 288 h. Three specific activities were evaluated: endoglucanase (CMCase), total activity (filter paper activity), and cellobiase. From a total of 390 strains of wild yeasts previously isolated, 16 strains performed cellulose hydrolysis, verified by the colorless halo in the solid medium. Among these 16 strains, 5 stood out as presenting higher levels of enzyme activity. The following step, screening in liquid medium, indicated only one strain as a potential producer of cellulases, named as AAJ6, for which the highest hydrolytic activity on carboxymethyl cellulose (0.33 U/ml) and filter paper (0.039 U/ml) was recorded. Afterwards, this wild yeast strain (AAJ6) was molecularly identified by sequencing the ITS1-5.8S-ITS2 and D1/D2 domains of the subunit (26 S) ribosomal DNA. Sequencing resulted in the identification of this strain as yeast-like fungus Acremonium strictum.Keywords: Acremonium strictum, screening, identification, yeast-like, cellulase
A possible relationship between the Arctic Oscillation Index and atmosphere-triggered interannual long-wavelength
A host of geophysical processes contribute to temporal variations
in the low-degree zonal harmonics of the Earth’s gravity field. The present paper
focuses on atmosphere-based mass redistributions using global surface pressure data
from the NOAA Climate Diagnostics Center for the period 1980-2002. We computed
atmosphere-triggered temporal variations of the Earth’s low-degree zonal gravitational
coefficients Jl (l = 2 : 4). Such atmosphere-triggered ΔJl(t) are compared
with the Arctic Oscillation Index (AOI) and with the observed ΔJl(t) computed by
the Italian Space Agency (ASI) so as to investigate a possible coupling. We show
that there is a significant agreement between the AOI and atmosphere-triggered
ΔJl(t), as well as a particularly interesting correlation between the winter ΔJl(t)
series and the AOI active season series
Aulogous fibrin sealant (Vivostat®) in the neurosurgical practice: Part II: Vertebro-spinal procedures
Background: Epidural hematomas, cerebrospinal fluid fistula, and spinal infections are challenging postoperative complications following vertebro-spinal procedures. We report our preliminary results using autologous fibrin sealant as both fibrin glue and a hemostatic during these operations. Methods: Prospectively, between January 2013 and March 2015, 68 patients received an autologous fibrin sealant prepared with the Vivostat®system applied epidurally to provide hemostasis and to seal the dura. The surgical technique, time to bleeding control, and associated complications were recorded. Results: Spinal procedures were performed in 68 patients utilizing autologous fibrin glue/Vivostat®to provide rapid hemostasis and/or to seal the dura. Only 2 patients developed postoperative dural fistulas while none exhibited hemorrhages, allergic reactions, systemic complications, or infections. Conclusions: In this preliminary study, the application of autologous fibrin sealant with Vivostat®resulted in rapid hemostasis and/or acted as an effective dural sealant. Although this product appears to be safe and effective, further investigations are warranted
A multi-century meteo-hydrological analysis for the Adda river basin (Central Alps). Part I: Gridded monthly precipitation (1800–2016) records
The 1800–2016 monthly precipitation record for the upper Adda river basin is presented. It is computed by applying the anomaly method to a quality-checked and homogenized observation database. The reconstruction accuracy and its evolution over the study period is evaluated at both station and grid-cell levels. The anomaly-based interpolation provides rather robust estimates even for the early years of sparse station coverage with basin precipitation reconstruction errors around 10%. The Theil-Sen trend analysis on the basin precipitation series shows significant (Mann-Kendall p value <.05) long-term tendencies of −3.8 ± 1.9% and −9.3 ± 3.8% century−1 for annual and autumn precipitation, respectively, even though the annual trend is not significant by excluding the first decades from the evaluation. As the basin precipitation record is expected to be underestimated due to the rain-gauge snow undercatch, the monthly precipitation fields are subjected to a correction procedure which allows to derive the multiplicative correcting constant to be applied to the basin annual precipitation series. The comparison between 1845 and 2016 yearly corrected precipitation and runoff records highlights current annual water losses of about 400 mm while the annual runoff coefficients exhibit a long-term significant decrease of −6.4 ± 1.0% century−1. This change in the hydrological cycle is mostly to be ascribed to the strong long-term reduction in annual runoff values (−11.8 ± 3.2% century−1) driven by increasing evapotranspiration due to both temperature increase and, likely, land-use changes
Impasse in the management of recurrent basal cell carcinoma of the skull with sagittal sinus erosion1
Abstract Basal cell carcinoma (BCC) is a non melanocytic skin cancer that arises from basal cells, affecting commonly fair-skinned human beings. Although the tumor is well known for local recurrences, extension into the intracranial space is reported. A case of a giant BCC of the scalp invading the middle and posterior third of the superior sagittal sinus (SSS) is reported. A 70-year-old male with a basal cell carcinoma history presented with a massive bleeding from the SSS invaded by the tumor. Since the patient refused surgery the bleeding was managed through direct compression by applying a thrombin-based hemostatic agents and sterile dressings. This procedure was performed daily in order to stimulate the spontaneous thrombosis of the dural sinus and development of collateral circle. BCC invading the SSS is rarely reported. A technical description of this case is provided. This case underscores the importance of early and appropriate treatment for high risk BCC, and whenever surgical procedure is not suitable appropriate conservative treatment may be efficacious
Clinical and radiological features of Forestier's disease presenting with dysphagia
Background: Diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier's disease, is a rheumatologic condition characterized by ossification of the spinal ligaments and tendons. Large anterior osteophytes are typically present in the lower cervical levels, while upper cervical ossification resulting in dysphagia is very rare. Methods: Here, we presented a patient with Forestier's disease involving massive ossification of the anterior longitudinal ligament extending from C3 to C4 downward contributing to severe dysphagia. Results: A 65‑year‑old male presented with cervical pain and dysphagia. The computed tomography of the cervical spine demonstrated massive anterior longitudinal ligament ossification (DISH) extending from C3 to C7. There was an additional large osteophyte at the C3‑C4 level, and also a high‑grade intracanalicular C6‑C7 cervical stenosis due to ossification of the posterior longitudinal ligament. The patient was offered surgical intervention (e.g., resection of the C3‑C7 anterior DISH and anterior cervical discectomy/fusion at the C6‑C7 level), but he declined. Conclusions: When conservative management fails to resolve severe dysphagia for cervical DISH/Forestier's disease, anterior surgical resection is typically performed. In this case, the patient refused surgery and opted for conservative management strategies
Delayed chronic intracranial subdural hematoma complicating resection of a tanycytic thoracic ependymoma
Background: To demonstrate that the diagnosis of an intracranial subdural hematoma should be considered for patients presenting with acute or delayed symptoms of intracranial pathology following resection of a spinal tumor. Case Description: We present a case of a 57-year-old woman found to have a chronic subdural hematoma 1 month following resection of a thoracic extramedullary ependymoma. Evacuation of the hematoma through a burr hole relieved the presenting symptoms and signs. Resolution of the hematoma was confirmed with a computed tomography (CT) scan. Conclusion: Headache and other symptoms not referable to spinal pathology should be regarded as a warning sign of an intracranial subdural hematoma, and a CT scan of the head should be obtained. The mechanism of the development of the hematoma may be related to the leakage of cerebrospinal fluid with subsequent intracranial hypotension leading to an expanding subdural space and hemorrhage
A rare case of extra-intramedullary dorsal tanycitic ependymoma, radically removed with intraoperative neurophysiological monitoring
Introduction: Tanycitic dorsal extra and intramedullary ependymoma is a rare form of tumor. From the histological point of view, these tumors show several aspects that make difficult the differential diagnosis from schwannomas and pilocytic astrocytomas. Tanycytic variant, often occurs in the thoracic tract of the spinal cord, and it is constituted by tanycites, that are typical elongated and bipolar cells that give to the tumor fibrillary aspects. Tanycitic variant has been recently characterized as a variant of ependymoma, since the 2000 World Health Organization (WHO) system. Case presentation: A 57 years old woman presented with intractable back pain often radiating to the left leg. Neurological exam revealed mild weakness in left tight flexion. No sensory or sphincterial disturbances were present. A dorso-lumbar Magnetic Resonance Imaging (MRI)with contrast medium showed a well-demarked T12 intradural extramedullary lesion, suggestive for schwannoma. The tumor was radically removed, with an excellent neurological outcome, and was then characterized as a grade II tanycitic ependymoma. Conclusion: To differentiate the diagnosis between extramedullary ependymomas and schwannomas, meningiomas or astrocytomas is necessary a histopathological examination and a close follow up period is recommended since the tumor could evolve into higher grade. Neurophysiological monitoring is necessary for a satisfactory neurological outcome
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