447 research outputs found
Professional Ethics, Provenance, and Policies: A Survey of Dead Sea Scrolls Scholars
This article presents and discusses the results of an online survey undertaken in 2018, which targeted scholars of the Dead Sea Scrolls and associated research fields. Respondents were asked questions on the state of knowledge in the field regarding provenance issues and related ethics and policies. The goal of the survey was to establish the levels of awareness within Qumran and related studies concerning the role of the antiquities market, the potential accountability (or not) of scholars as perceived by respondents, as well as their general awareness of relevant policies and codes of conduct. The article discusses the key points that the survey raised, with the aim of offering textual scholars tools to assess their role in provenance issues.Peer reviewe
Magnetically driven dielectric and structural behavior in Bi0.5La0.5FeO3
The authors would like to thank the Royal Society for a University Research Fellowship (FDM), Engineering and Physical Sciences Research Council for a studentship (CMK), and the Science and Technology Facilities Council for access to neutron facilities.A detailed structural analysis of the antiferromagnetic (Gz-type) lanthanum doped bismuth ferrite - Bi0.5La0.5FeO3 (Pn′ma′) – using variable-temperature powder neutron diffraction is reported. The analysis highlights a structural link between changes in the relative dielectric permittivity and changes in the FeO6 octahedral tilt magnitudes, accompanied by a structural distortion of the octahedra with corresponding A-site displacement along the c-axis; this behavior is unusual due to an increasing in-phase tilt mode with increasing temperature. The anomalous orthorhombic distortion is driven by magnetostriction at the onset of antiferromagnetic ordering resulting in an Invar effect along the magnetic c-axis and anisotropic displacement of the A-site Bi3+ and La3+ along the a-axis.PostprintPeer reviewe
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Barriers and Facilitators to Implementation of Value-Based Care Models in New Medicaid Accountable Care Organizations in Massachusetts: A Study Protocol
Introduction: Massachusetts established 17 new Medicaid accountable care organizations (ACOs) and 24 affiliated Community Partners (CPs) in 2018 as part of a large-scale healthcare reform effort to improve care value. The new ACOs will receive $1.8 billion dollars in state and federal funding over 5 years through the Delivery System Reform Incentive Program (DSRIP). The multi-faceted study described in this protocol aims to address gaps in knowledge about Medicaid ACOs\u27 impact on healthcare value by identifying barriers and facilitators to implementation and sustainment of the DSRIP-funded programs.
Methods and analysis: The study\u27s four components are: (1) Document Review to characterize the ACOs and CPs; (2) Semi-structured Key Informant Interviews (KII) with ACO and CP leadership, state-level Medicaid administrators, and patients; (3) Site visits with selected ACOs and CPs; and (4) Surveys of ACO clinical teams and CP staff. The Consolidated Framework for Implementation Research\u27s (CFIR) serves as the study\u27s conceptual framework; its versatile menu of constructs, arranged across five domains (Intervention Characteristics, Inner Setting, Outer Setting, Characteristics of Individuals, and Processes) guides identification of barriers and facilitators across multiple organizational contexts. For example, KII interview guides focus on understanding how Inner and Outer Setting factors may impact implementation. Document Review analysis includes extraction and synthesis of ACO-specific DSRIP-funded programs (i.e., Intervention Characteristics); KIIs and site visit data will be qualitatively analyzed using thematic analytic techniques; surveys will be analyzed using descriptive statistics (e.g., counts, frequencies, means, and standard deviations).
Discussion: Understanding barriers and facilitators to implementing and sustaining Medicaid ACOs with varied organizational structures will provide critical context for understanding the overall impact of the Medicaid ACO experiment in Massachusetts. It will also provide important insights for other states considering the ACO model for their Medicaid programs.
Ethics and dissemination: IRB determinations were that the overall study did not constitute human subjects research and that each phase of primary data collection should be submitted for IRB review and approval. Study results will be disseminated through traditional channels such as peer reviewed journals, through publicly available reports on the mass.gov website; and directly to key stakeholders in ACO and CP leadership
Factors that differentiate distressed and non-distressed marriages in army soldiers
Data from U.S. Army soldiers (N = 697) were analyzed to determine the factors that differentiate distressed from non-distressed relationships. Results show that most soldiers had relationship satisfaction scores that categorized them as non-distressed. In addition, soldiers in dual-military marriages had relationship satisfaction scores similar to those of soldiers in military-civilian marriages. Finally, several variables including rank, relocation status, relationship length, and relationship status differentiated distressed from non-distressed relationships. Implications for intervention programming and future research directions are discussed
The Essence of Innocence: Consequences of Dehumanizing Black Children
This research, consisting of four studies of police officers and college students, finds that Black boys as young as 10 may not be viewed in the same light of childhood innocence as their white peers. Instead, they are more likely to be mistaken as older, be perceived as guilty, and face police violence if accused of a crime. The research provides evidence that these racial disparities are predicted by the implicit dehumanization of Blacks
Can Opioid-Free Anaesthesia Be Personalised? : A Narrative Review
Acknowledgments The authors would like to thank Marc De Kock for his contribution to the conceptualization of this work.Peer reviewedPublisher PD
STEM gender stereotypes from early childhood through adolescence at informal science centers.
Stereotypes about science, technology, engineering and mathematics (STEM) are associated with reduced STEM engagement amongst girls and women. The present study examined these stereotypes from early childhood through adolescence within informal science learning sites (ISLS; science museums, zoos, aquariums). Further, the study explored whether interactions with male or female educators influenced STEM stereotypes. Participants (n = 997, female = 572) were ISLS visitors in the UK and USA who either interacted with an educator, or no educator. With age participants were more likely to report that "both boys and girls" are "usually", "should" be, and "can" be good at STEM. Independent of age, male participants reported that their own gender group "should" be good at STEM. Educator interactions did not influence stereotype responses. These results highlight early childhood as a key developmental window in which to challenge ideas about who can and should be proficient in STEM
Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
Retroviral reverse transcriptase (RT) of Moloney murine leukemia virus (MoMLV) is expressed in the form of a large Gag–Pol precursor protein by suppression of translational termination in which the maximal efficiency of stop codon read-through depends on the interaction between MoMLV RT and peptidyl release factor 1 (eRF1). Here, we report the crystal structure of MoMLV RT in complex with eRF1. The MoMLV RT interacts with the C-terminal domain of eRF1 via its RNase H domain to sterically occlude the binding of peptidyl release factor 3 (eRF3) to eRF1. Promotion of read-through by MoMLV RNase H prevents nonsense-mediated mRNA decay (NMD) of mRNAs. Comparison of our structure with that of HIV RT explains why HIV RT cannot interact with eRF1. Our results provide a mechanistic view of how MoMLV manipulates the host translation termination machinery for the synthesis of its own proteins
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