Theory of low frequency noise transmission through turbines

Improvements of the existing theory of low frequency noise transmission through turbines and development of a working prediction tool are described. The existing actuator-disk model and a new finite-chord model were utilized in an analytical study. The interactive effect of adjacent blade rows, higher order spinning modes, blade-passage shocks, and duct area variations were considered separately. The improved theory was validated using the data acquired in an earlier NASA program. Computer programs incorporating the improved theory were produced for transmission loss prediction purposes. The programs were exercised parametrically and charts constructed to define approximately the low frequency noise transfer through turbines. The loss through the exhaust nozzle and flow(s) was also considered

Attenuation of upstream-generated low frequency noise by gas turbines

The acoustic transfer functions of low frequency (below 3500 Hz) noise through aircraft turbines were investigated. Model test results were compared with theoretical predictions in order to assess the validity of the theory. Component tests were conducted on both high pressure and low pressure model turbines. The influence of inlet temperature and turbine speed attenuation was evaluated, while the effects of turbine pressure ratio, blade-row choking, and additional downstream stages were determined. Preliminary identification of pertinent aeroacoustic correlating parameters was made

Human health risk assessment of temporal and spatial variations of ground water quality at a densely industrialized commercial complex at Haridwar, India

The observations of present investigation revealed that the groundwater regime at State Infrastructure and Industrial Development Corporation of Uttarakhand Limited (SIDCUL) Industrial Estate (IE) was highly responsive to the anthropogenic stress of recharge and discharge parameters concerning the distressing industrial activities. The present study on groundwater characteristics of SIDCUL-IE, Haridwar in year 2013-2014 showed that the water of Sampling station-D (SSD) had relatively poor quality in comparison to the groundwater collected from Sampling station-A (SSA), Sampling station-B (SSB) and Sampling station-C (SSC). The samples had a high mineral load with relatively wider pH range. The physico-chemical parameters like pH (6.35 in October) at SSA, TDS (553.5 mg/l in November) at SSC, TH (600.0 mg/l in July) at SSB and alkalinity (525.0 mg/l in October) at SSD were beyond the prescribed limits of Bureau of Indian Standards (BIS). The Karl Pearson correlation matrix showed moderate to significantly positive correlation between various parameters like COD-phosphorus (r=0.629), temperature-DO (r=-0.477) at SSA; pH and bicarbonate (r=0.668) at SSB; pH-temperature (r=-0.551),turbidity-BOD (r=0.467), BOD-phosphorus (r=0.518), bicarbonate-acidity (r=-0.833) at SSC and TSS-turbidity (r=0.616), BOD-COD (r=0.6771) at SSD and temperature-DO (r=-0.666), hardness-acidity (r=-0.6542) BOD-COD (r=0.654) at control site. The overall quality of groundwater, though hard, was found acceptable for drinking purpose. The divergence in the results of groundwater samples taken from SIDCUL-IE and the Control site, 2 km away from SIDCUL-IE, indicated that groundwater pollution is increasing alarmingly which may have serious threats to human health in near future

Role of microRNAs (miRNAs) in the pathophysiology of Diabetes mellitus

© 2017 EDIZIONI MINERVA MEDICA. Diabetes mellitus is becoming the critical problem among the entire world and it is difficult to understand the molecular mechanism representing the concept of diabetic pathology. Recently the knowledge of the involvement of genetics in type 2 diabetes mellitus (T2DM) susceptibility has sketched a great concentration towards the transcriptional activity of β cells within the pancreas. This disease becomes the leading cause of death, so it is necessary to study the molecular pathogenesis, phenotypes, and characteristics to design the therapeutic parameters. Here in this review role of miRNA is being illustrated as it plays a crucial role in the pathogenesis, progression, and fate of beta cells of pancreas regulating the insulin secretion. Here in this review, we try to include the effects and pathophysiology of various miRNA in diabetes mellitus and on the various sites of the human body

In-beam spectroscopy of medium- and high-spin states in 133^{133}Ce

Medium and high-spin states in $^{133}$Ce were investigated using the $^{116}$Cd($^{22}$Ne, $5n$) reaction and the Gammasphere array. The level scheme was extended up to an excitation energy of $\sim22.8$ MeV and spin 93/2 . Eleven bands of quadrupole transitions and two new dipole bands are identified. The connections to low-lying states of the previously known, high-spin triaxial bands were firmly established, thus fixing the excitation energy and, in many cases, the spin parity of the levels. Based on comparisons with cranked Nilsson-Strutinsky calculations and tilted axis cranking covariant density functional theory, it is shown that all observed bands are characterized by pronounced triaxiality. Competing multiquasiparticle configurations are found to contribute to a rich variety of collective phenomena in this nucleus.Comment: 20 pages, 11 figure

Testing the Mutually Enhanced Magicity Effect in Nuclear Incompressibility via the Giant Monopole Resonance in the 204,206,208^{204,206,208}Pb Isotopes

Using inelastic $\alpha$-scattering at extremely forward angles, including $0^\circ$, the strength distributions of the isoscalar giant monopole resonance (ISGMR) have been measured in the $^{204,206,208}$Pb isotopes in order to examine the proposed mutually enhanced magicity (MEM) effect on the nuclear incompressibility. The MEM effect had been suggested as a likely explanation of the "softness" of nuclear incompressibility observed in the ISGMR measurements in the Sn and Cd isotopes. Our experimental results rule out any manifestation of the MEM effect in nuclear incompressibility and leave the question of the softness of the open-shell nuclei unresolved still.Comment: Accepted for publication in Physics Letters B. Very minor changes in tex

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.

Developmental progression depends on temporally defined changes in gene expression mediated by transient exposure of lineage intermediates to signals in the progenitor niche. To determine whether cell-intrinsic epigenetic mechanisms contribute to signal-induced transcriptional responses, here we manipulate the signalling environment and activity of the histone demethylase LSD1 during differentiation of hESC-gut tube intermediates into pancreatic endocrine cells. We identify a transient requirement for LSD1 in endocrine cell differentiation spanning a short time-window early in pancreas development, a phenotype we reproduced in mice. Examination of enhancer and transcriptome landscapes revealed that LSD1 silences transiently active retinoic acid (RA)-induced enhancers and their target genes. Furthermore, prolonged RA exposure phenocopies LSD1 inhibition, suggesting that LSD1 regulates endocrine cell differentiation by limiting the duration of RA signalling. Our findings identify LSD1-mediated enhancer silencing as a cell-intrinsic epigenetic feedback mechanism by which the duration of the transcriptional response to a developmental signal is limited

Promoção do consumo de frutas, legumes e verduras em Unidades de Educação Infantil: diagnóstico inicial.

Seleção do público-alvo e coleta de dados nas unidades de educação infantil; Diagnóstico do ambiente nas unidades de educação infantil; Consumo de frutas, legumes e verduras das crianças das unidades de educação infantil, segundo os pais/responsáveis; Consumo de frutas, legumes e verduras das crianças das unidades de educação infantil, segundo os recreadores/professores; Informações sobre os recreadores/professores nas unidades de educação infantil; Consumo de frutas, legumes e verduras das crianças das unidades de educação infantil, segundo as merendeiras; Informações sobre as merendeiras nas unidades de educação infantil; Aceitação de frutas, legumes e verduras pelas crianças nas unidades de educação infantil, segundo observação.bitstream/item/84158/1/2008-DOC-0088.pd