Quality Assurance of Software Applications Using the In Vivo Testing Approach

Software products released into the field typically have some number of residual defects that either were not detected or could not have been detected during testing. This may be the result of flaws in the test cases themselves, incorrect assumptions made during the creation of test cases, or the infeasibility of testing the sheer number of possible configurations for a complex system; these defects may also be due to application states that were not considered during lab testing, or corrupted states that could arise due to a security violation. One approach to this problem is to continue to test these applications even after deployment, in hopes of finding any remaining flaws. In this paper, we present a testing methodology we call in vivo testing, in which tests are continuously executed in the deployment environment. We also describe a type of test we call in vivo tests that are specifically designed for use with such an approach: these tests execute within the current state of the program (rather than by creating a clean slate) without affecting or altering that state from the perspective of the end-user. We discuss the approach and the prototype testing framework for Java applications called Invite. We also provide the results of case studies that demonstrate Invite's effectiveness and efficiency

Generative User-Experience Research for Developing Domain-specific Natural Language Processing Applications

User experience (UX) is a part of human-computer interaction (HCI) research and focuses on increasing intuitiveness, transparency, simplicity, and trust for system users. Most of the UX research for machine learning (ML) or natural language processing (NLP) focuses on a data-driven methodology, i.e., it fails to focus on users' requirements, and engages domain users mainly for usability evaluation. Moreover, more typical UX methods tailor the systems towards user usability, unlike learning about the user needs first. The paper proposes a methodology for integrating generative UX research into developing domain NLP applications. Generative UX research employs domain users at the initial stages of prototype development, i.e., ideation and concept evaluation, and the last stage for evaluating the change in user value. In the case study, we report the full-cycle prototype development of a domain-specific semantic search for daily operations in the process industry. Our case study shows that involving domain experts increases their interest and trust in the final NLP application. Moreover, we show that synergetic UX+NLP research efficiently considers data- and user-driven opportunities and constraints, which can be crucial for NLP applications in narrow domain

Consistency between ARPES and STM measurements on SmB6_6

Strongly correlated topological surface states are promising platforms for next-generation quantum applications, but they remain elusive in real materials. The correlated Kondo insulator SmB$_6$ is one of the most promising candidates, with theoretically predicted heavy Dirac surface states supported by transport and scanning tunneling microscopy (STM) experiments. However, a puzzling discrepancy appears between STM and angle-resolved photoemission (ARPES) experiments on SmB$_6$. Although ARPES detects spin-textured surface states, their velocity is an order of magnitude higher than expected, while the Dirac point -- the hallmark of any topological system -- can only be inferred deep within the bulk valence band. A significant challenge is that SmB$_6$ lacks a natural cleavage plane, resulting in ordered surface domains limited to 10s of nanometers. Here we use STM to show that surface band bending can shift energy features by 10s of meV between domains. Starting from our STM spectra, we simulate the full spectral function as an average over multiple domains with different surface potentials. Our simulation shows excellent agreement with ARPES data, and thus resolves the apparent discrepancy between large-area measurements that average over multiple band-shifted domains and atomically-resolved measurements within a single domain

Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand

We have constructed an artificial ligand for the hepatocyte-specific asialoglycoprotein receptor for the purpose of generating a synthetic delivery system for DNA. This ligand has a tetra-antennary structure, containing four terminal galactose residues on a branched carrier peptide. The carbohydrate residues of this glycopeptide were introduced by reductive coupling of lactose to the alpha- and epsilon-amino groups of the two N-terminal lysines on the carrier peptide. The C-terminus of the peptide, containing a cysteine separated from the branched N-terminus by a 10 amino acid spacer sequence, was used for conjugation to 3-(2-pyridyldithio)propionate-modified polylysine via disulfide bond formation. Complexes containing plasmid DNA bound to these galactose-polylysine conjugates have been used for asialoglycoprotein receptor-mediated transfer of a luciferase gene into human (HepG2) and murine (BNL CL.2) hepatocyte cell lines. Gene transfer was strongly promoted when amphipathic peptides with pH-controlled membrane-disruption activity, derived from the N-terminal sequence of influenza virus hemagglutinin HA-2, were also present in these DNA complexes. Thus, we have essentially borrowed the small functional domains of two large proteins, asialoglycoprotein and hemagglutinin, and assembled them into a supramolecular complex to generate an efficient gene-transfer system

Spin-polarized imaging of strongly interacting fermions in the ferrimagnetic state of Weyl candidate CeBi

CeBi has an intricate magnetic phase diagram whose fully-polarized state has recently been suggested as a Weyl semimetal, though the role of $f$ states in promoting strong interactions has remained elusive. Here we focus on the less-studied, but also time-reversal symmetry-breaking ferrimagnetic phase of CeBi, where our density functional theory (DFT) calculations predict additional Weyl nodes near the Fermi level $E_\mathrm{F}$. We use spin-polarized scanning tunneling microscopy and spectroscopy to image the surface ferrimagnetic order on the itinerant Bi $p$ states, indicating their orbital hybridization with localized Ce $f$ states. We observe suppression of this spin-polarized signature at $E_\mathrm{F}$, coincident with a Fano line shape in the conductance spectra, suggesting the Bi $p$ states partially Kondo screen the $f$ magnetic moments, and this $p-f$ hybridization causes strong Fermi-level band renormalization. The $p$ band flattening is supported by our quasiparticle interference (QPI) measurements, which also show band splitting in agreement with DFT, painting a consistent picture of a strongly interacting magnetic Weyl semimetal

Inference on inspiral signals using LISA MLDC data

In this paper we describe a Bayesian inference framework for analysis of data obtained by LISA. We set up a model for binary inspiral signals as defined for the Mock LISA Data Challenge 1.2 (MLDC), and implemented a Markov chain Monte Carlo (MCMC) algorithm to facilitate exploration and integration of the posterior distribution over the 9-dimensional parameter space. Here we present intermediate results showing how, using this method, information about the 9 parameters can be extracted from the data.Comment: Accepted for publication in Classical and Quantum Gravity, GWDAW-11 special issu

Visualizing the atomic-scale origin of metallic behavior in Kondo insulators

A Kondo lattice is often electrically insulating at low temperatures. However, several recent experiments have detected signatures of bulk metallicity within this Kondo insulating phase. Here we visualize the real-space charge landscape within a Kondo lattice with atomic resolution using a scanning tunneling microscope. We discover nanometer-scale puddles of metallic conduction electrons centered around uranium-site substitutions in the heavy-fermion compound URu$_2$Si$_2$, and around samarium-site defects in the topological Kondo insulator SmB$_6$. These defects disturb the Kondo screening cloud, leaving behind a fingerprint of the metallic parent state. Our results suggest that the mysterious 3D quantum oscillations measured in SmB$_6$ could arise from these Kondo-lattice defects, although we cannot rule out other explanations. Our imaging technique could enable the development of atomic-scale charge sensors using heavy-fermion probes

Deep extragalactic visible legacy survey (DEVILS): the emergence of bulges and decline of disc growth since z = 1

We present a complete structural analysis of the ellipticals (E), diffuse bulges (dB), compact bulges (cB), and discs (D) within a redshift range 0 \u3c z \u3c 1, and stellar mass log10(M*/M⊙) ≥ 9.5 volume-limited sample drawn from the combined DEVILS and HST-COSMOS region. We use the PROFIT code to profile over ∼35 000 galaxies for which visual classification into single or double component was pre-defined in Paper-I. Over this redshift range, we see a growth in the total stellar mass density (SMD) of a factor of 1.5. At all epochs we find that the dominant structure, contributing to the total SMD, is the disc, and holds a fairly constant share of ∼60 per cent role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-variant: inherit; font-stretch: inherit; line-height: normal; font-family: inherit; vertical-align: baseline; display: inline; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; position: relative; \u3e∼60 per cent∼60 per cent of the total SMD from z = 0.8 to z = 0.2, dropping to ∼30 per cent role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-variant: inherit; font-stretch: inherit; line-height: normal; font-family: inherit; vertical-align: baseline; display: inline; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; position: relative; \u3e∼30 per cent∼30 per cent at z = 0.0 (representing ∼33 per cent role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-variant: inherit; font-stretch: inherit; line-height: normal; font-family: inherit; vertical-align: baseline; display: inline; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; position: relative; \u3e∼33 per cent∼33 per cent decline in the total disc SMD). Other classes (E, dB, and cB) show steady growth in their numbers and integrated stellar mass densities. By number, the most dramatic change across the full mass range is in the growth of diffuse bulges. In terms of total SMD, the biggest gain is an increase in massive elliptical systems, rising from 20 per cent at z = 0.8 to equal that of discs at z = 0.0 (30 per cent) representing an absolute mass growth of a factor of 2.5. Overall, we see a clear picture of the emergence and growth of all three classes of spheroids over the past 8 Gyr, and infer that in the later half of the Universe’s timeline spheroid-forming processes and pathways (secular evolution, mass-accretion, and mergers) appear to dominate mass transformation over quiescent disc growth

Rotation symmetry breaking in La2−xSrxCuO4{\mathrm{La}}_{2-x}{\mathrm{Sr}}_{x}{\mathrm{CuO}}_{4} revealed by angle-resolved photoemission spectroscopy

Using angle-resolved photoemission spectroscopy it is revealed that in the vicinity of optimal doping the electronic structure of La2−xSrxCuO4 cuprate undergoes an electronic reconstruction associated with a wave vector qa=(π,0). The reconstructed Fermi surface and folded band are distinct to the shadow bands observed in BSCCO cuprates and in underdoped La2−xSrxCuO4 with x≤0.12, which shift the primary band along the zone diagonal direction. Furthermore, the folded bands appear only with qa=(π,0) vector, but not with qb=(0,π). We demonstrate that the absence of qb reconstruction is not due to the matrix-element effects in the photoemission process, which indicates the fourfold symmetry is broken in the system