A Large Periureteral Lipoma Associated with Renal Lithiasis and Hydronephrosis.

A rare case of large periureteral lipoma in a 66-year-old woman is reported. The tumor measuring 16×7×7cm in size was located from the upper portion of the right ureter to the renal pelvis. It is considered that the severe hydronephrosis and renal lithiasis occurred as a result of stenosis in the upper urinary tract due to compression by the tumor. Although the differential diagnosis was difficult radiologically, the tumor was easily diagnosed as lipoma by hi stop athological investigation

Mammary and extramammary Paget's disease

Paget's disease, described by Sir James Paget in 1874, is classified as mammary and extramammary. the mammary type is rare and often associated with intraductal cancer (93-100% of cases). It is more prevalent in postmenopausal women and it appears as an eczematoid, erythematous, moist or crusted lesion, with or without fine scaling, infiltration and inversion of the nipple. It must be distinguished from erosive adenomatosis of the nipple, cutaneous extension of breast carcinoma, psoriasis, atopic dermatitis, contact dermatitis, chronic eczema, lactiferous ducts ectasia, Bowen's disease, basal cell carcinoma, melanoma and intraductal papilloma. Diagnosis is histological and prognosis and treatment depend on the type of underlying breast cancer. Extramammary Paget's disease is considered an adenocarcinoma originating from the skin or skin appendages in areas with apocrine glands. the primary location is the vulvar area, followed by the perianal region, scrotum, penis and axillae. It starts as an erythematous plaque of indolent growth, with well-defined edges, fine scaling, excoriations, exulcerations and lichenification. in most cases it is not associated with cancer, although there are publications linking it to tumors of the vulva, vagina, cervix and corpus uteri, bladder, ovary, gallbladder, liver, breast, colon and rectum. Differential diagnoses are candidiasis, psoriasis and chronic lichen simplex. Histopathology confirms the diagnosis. Before treatment begins, associated malignancies should be investigated. Surgical excision and micrographic surgery are the best treatment options, although recurrences are frequent.Univ Fed Piaui, Teresina, PI, BrazilUniversidade Federal de São Paulo, São Paulo, SP, BrazilUNISA, Santo Amaro, SP, BrazilHosp Servidor Publ Municipal São Paulo, São Paulo, SP, BrazilFMABC, Santo Andre, SP, BrazilUniversidade Federal de São Paulo, São Paulo, SP, BrazilWeb of Scienc

UTILIDADE DA GRISEOFULVINA NO TRATAMENTO DO GRANULOMA ACTÍNICO DE O’BRIEN

Actinic granuloma of O’Brien, also called annular elastolytic giant cell granuloma is a rare condition. It shows clinically as papules lesions that converge in annular plaques lesions with an atrophic center. Histologically, it evidences elastophagocytosis and elastolysis. The case below describes a female patient, 53 years old, that had classical clinical and histopathological lesions of actinic granuloma that showed a significant improvement upon the introduction of adjunctive griseofulvin therapy.O granuloma actiníco de O’Brien, ou também chamado de granuloma anular elastolítico de células gigantes é uma afecção rara. Apresenta-se clinicamente como pápulas que se confluem formando lesões anulares com centro atrófico. Histologicamente, evidencia-se elastofagocitose e elastólise. O seguinte caso relata uma paciente com 53 anos, que apresentava lesões clínicas e histopatológicas clássicas de granuloma actínico que evoluiu com melhora importante no tratamento adjuvante com griseofulvina