Generating Diophantine Sets by Virus Machines

Virus Machines are a computational paradigm inspired by the manner in which viruses replicate and transmit from one host cell to another. This paradigm provides non-deterministic sequential devices. Non-restricted virus machines are unbounded virus machines, in the sense that no restriction on the number of hosts, the number of instructions and the number of viruses contained in any host along any computation is placed on them. The computational completeness of these machines has been obtained by simulating register machines. In this paper, virus machines as set generating devices are considered. Then, the universality of non-restricted virus machines is proved by showing that they can compute all diophantine sets, which the MRDP theorem proves that coincide with the recursively enumerable sets.Ministerio de Economía y Competitividad TIN2012- 3743

Indicadores de daño psíquico en entrevistas a sujetos víctimas de accidentes de tránsito judicializados por demanda de daños y perjuicios

La problemática del daño psicológico viene ocupando un lugar trascendental en el derecho de daños, y se ha expandido por diversos ámbitos jurídicos, solicitando a los profesionales de la salud mental, su evaluación y demostración. Se trata por tanto, de una zona de entrecruzamiento entre el discurso jurídico, que recién comienza a adentrarse en la problemática, y las disciplinas que estudian la salud mental, que se presentan como un complejo espectro de posibilidades. Este trabajo pretende aportar conocimiento científico, con criterios distintivos cargados de provisoriedad, y dejar planteados interrogantes para conclusiones posteriores que cuenten con un aceptable consenso. Consiste en una investigación de tipo cualitativa: estudio descriptivo realizado con sujetos víctimas de accidentes de tránsito, judicializados por demanda de daños y perjuicios, en la ciudad de Resistencia - Chaco, en el período enero 2011 - septiembre 2012. Se utiliza el método comparativo constante para analizar, describir, y disponer en categorías los indicadores de daño psíquico identificados. Se concluye que, tales indicadores se pueden organizar en cinco categorías centrales: 1.- Crisis en la identidad, 2.- Secuelas psicosociales, 3.- Recuerdos intrusivos del accidente, 4.- Cambios en la concepción de la imagen corporal, y 5.- Necesidad de ser escuchado. Cada una de ellas es a su vez, desglosada en subcategorías.Issues related to psychological damage are nowadays taking an important role in the tort law. They have also expanded through different legal fields, requiring an evaluation and demonstration by proffesionals of mental health. It is, therefore, a cross-linked zone between legal discourse, which is beginning to deal with it, and the mental health study fields, which are presented as a wide spectrum range of possibilities. It is the aim of this paper to provide scientific knowledge with a distintic criteria, and also to set a precedent for posterior questions and conclusions within an acceptable consensus. It is a qualitative research: a descriptive study done with subjects involved in traffic accident, which had been judicialized for damages demands, in Resistencia – Chaco between Jan. 2011 and Sept 2012. The constant comparative method is used to analyze, describe and categorize he indexes of Psichic Damage identified. In conclusion, the indexes can be classified into five main categories: 1- Identity crisis, 2- Psichological sequels, 3- Intrusive memories of the accident, 4- Changes as regard body image conceptions, 5- The need to be listened to. Any of the preceding categories are at the same time divided into subcategories.Fil: Matijasevich, Melis

Breastfeeding and the Development of Socio-Emotional Competencies: A Systematic Review

Aim: To assess the current scientific evidence about the relationship between breastfeeding and the development of infant’s socio-emotional competencies. Materials and Methods: A systematic review of literature was conducted through PubMed, LILACS (Literatura Latinoamericana y del Caribe en Ciencias de la Salud), and PsycINFO of population-based cohorts. Records were screened, data extracted, and a quality assessment performed by two authors independently. Results: Thirteen studies were included in the review with six finding a statistically significant association between breastfeeding and the development of socio-emotional competencies such as problem solving, agreeableness, and optimism. In five studies, no statistically significant association was found, and in three, a negative association existed. Regarding quality assessment, four studies had a strong global rating, four had a moderate rating, and five had a weak global rating. Conclusion: Almost half (6/13) of the studies found a positive association between breastfeeding and the development of social-emotional competencies in infants; however, a great heterogeneity was present in the quality of the included studies. There is a need for further and higher quality research into this field of stud

The Influence of Human-Milk Substitutes Marketing on Breastfeeding Intention and Practice among Native and Immigrant Brazilians

Background: The International Code of Marketing of Breast-Milk Substitutes is a global public health policy aiming to protect breastfeeding from the influence of human-milk substitutes marketing. Brazil is one of the few countries substantially implementing it. Most countries adopted selected provisions, including Portugal. Research Aim: To explore whether Brazilians’ perspectives about breastfeeding intention and practice are influenced by human-milk substitutes marketing upon migration to Portugal. Methods: A qualitative, prospective, cross-sectional survey design was conducted in Brazil and Portugal (2018–2019). Qualitative semi-structured interviews were performed with native (n = 16) and immigrant (n = 15) Brazilians. Women aged 18 or above, mothers of 0–12 month infants, and without contraindications to breastfeed, were eligible for the study. Heterogeneity sampling was employed based on socioeconomic status and infants’ age. Content analysis was conducted using NVivo. Results: Brazilian immigrants were more aware of the potential negative influence of human-milk substitutes marketing than natives. Sociocultural factors contributed to Brazilian immigrants being less permeable to the influence of human-milk substitutes marketing in the host country, where a less protective breastfeeding environment was perceived. Conclusions: Sociocultural factors including breastfeeding promotion strategies and a strong breastfeeding culture in the home country appear to play a protective role on breastfeeding intention and practice among Brazilians migrating to Portugal. © The Author(s) 2022.The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study is funded by FEDER funds through the Operational Programme for Competitiveness and Internationalization, and by national funding through the Foundation for Science and Technology (FCT; Portuguese Ministry of Science, Technology and Higher Education), under the scope of the project ‘‘Perinatal Health in Migrants: Barriers, Incentives and Outcomes’’ (POCI-01-0145-FEDER-016874; PTDC/DTPSAP/6384/2014), the projects UIDB/04750/2020 e LA/P/0064/2020, the PhD grant PD/BD/128082/2016 (C. L.) co-funded by the FCT and Human Potential Operating Program of the European Social Fund (POPH/FSE Program) and the contract DL57/2016/CP1336/CT0001 (C.F.). A. M. has a research scholarship from the Brazilian National Council for Scientific and Technological Development (CNPq)

The relationship between indicators of socioeconomic status and cesarean section in public hospitals

OBJECTIVE To assess the relationship between indicators of socioeconomic status and cesarean section in public hospitals that adopt standardized protocols of obstetrical care. METHODS This was a prospective cohort study conducted between May 2005 and January 2006 with 831 pregnant women recruited from 10 public primary care clinics in São Paulo, Brazil. Demographic and clinical characteristics were collected during pregnancy. The three main exposures were schooling, monthly family income per capita, and residential crowding. The main outcome was cesarean section at three public hospitals located in the area. Crude and adjusted risk ratios (RR), with 95% confidence intervals were calculated using Poisson regression with robust variance. We examined the effects of each exposure variable on cesarean section accounting for potential confounders by using four different models: crude, adjusted by mother’s characteristics, by obstetrical complications, and by the other two indicators of socioeconomic status. RESULTS Among the 757 deliveries performed in the public hospitals, 215 (28.4%) were by cesarean section. In the bivariate analysis, cesarean section was associated with higher family income per capita, higher education, lower residential crowding, pregnancy planning, white skin color, having a partner, and advanced maternal age. In the multivariate analysis, after adjustment for covariates, none of the socioeconomic status variables remained associated with cesarean section. CONCLUSIONS In this group, the chance of women undergoing cesarean section was not associated with indicators of socioeconomic status only, but was defined in accordance with major obstetric and clinical conditions

Internal consistency of the Strengths and Difficulties Questionnaire in Amazonian children

OBJECTIVE: To describe the frequency of behavioral problems and the internal consistency of the parent version of the Strengths and Difficulties Questionnaire (SDQ-P) in Amazonian preschool children during the covid-19 pandemic. METHODS: Data from the Maternal and Child Health and Nutrition in Acre (MINA-Brazil) study, a population-based birth cohort in the Western Brazilian Amazon, were used. The SDQ-P was applied in 2021 at the five-year follow-up visit to parents or caregivers of 695 children (49.4% of which were girls). This instrument is a short behavioral screening questionnaire composed of 25 items reorganized into five subscales: emotional symptoms, conduct problems, hyperactivity/inattention, peer relationship problems, and prosocial behavior. Cases of behavioral problems were defined according to the original SDQ cut-offs based on United Kingdom norms. Moreover, cut off points were estimated based on the SDQ-P percentile results of our study sample. Internal consistency was assessed by calculating Cronbach’s alpha coefficient and McDonald’s omega for each scale. RESULTS: According to the cut-offs based on our studied population distribution, 10% of all children had high or very high total difficulty scores, whereas it was almost twice when the original SDQ cut-offs based on United Kingdom norms, were applied (18%). Differences were also observed in the other scales. Compared to girls, boys showed higher means of externalizing problem and lower means of prosocial behavior. The five-factor model showed a moderate internal consistency of the items for all scales (0.60 ≤ α ≤ 0.40), except for total difficulty scores, which it considered substantial (α > 0.61). CONCLUSIONS: Our results support the usefulness of SDQ in our study population and reinforce the need for strategies and policy development for mental health care in early life in the Amazon

Prevalence and correlates of childhood anemia in the MINA-Brazil birth cohort study

OBJECTIVE: To describe the prevalence and predictors of childhood anemia in an Amazonian population-based birth cohort study. METHODS: We estimated the prevalence of maternal anemia at delivery (hemoglobin [Hb] concentration < 110 g/L) in women participating in the MINA-Brazil birth cohort study and in their children examined at 1 and 2 years (Hb < 110 g/L) and at 5 years of age (Hb < 115 g/L). We measured ferritin, soluble transferrin receptor, and C-reactive protein concentrations in mothers at delivery and in their 1- and 2-year old children to estimate the prevalence of iron deficiency and its contribution to anemia, while adjusting for potential confounders by multiple Poisson regression analysis (adjusted relative risk [RRa]). RESULTS: The prevalence 95% confidence interval (CI) of maternal anemia, iron deficiency, and iron-deficiency anemia at delivery were 17.3% (14.0–21.0%), 42.6% (38.0–47.2%), and 8.7% (6.3–11.6)%, respectively (n = 462). At age 1 year (n = 646), 42.2% (38.7–45.8%) of the study children were anemic, 38.4% (34.6–42.3%) were iron-deficient, and 26.3 (23.0–29.9) had iron-deficiency anemia. Prevalence had decreased to 12.8% (10.6–15.2%), 18.1% (15.5–21.1%), and 4.1% (2.8–5.7%), respectively, at 2 years (n = 761); at 5 years of age, 5.2% (3.6–7.2%) children were anemic (n = 655). Iron deficiency (RRa = 2.19; 95%CI: 1.84–2.60) and consumption of ultraprocessed foods (UPF) (RRa = 1.56; 95%CI: 1.14–2.13) were significant contributors to anemia at 1 year, after adjusting for maternal schooling. At 2 years, anemia was significantly associated with maternal anemia at delivery (RRa: 1.67; 95%CI: 1.17–2.39), malaria since birth (2.25; 1.30–3.87), and iron deficiency (2.15; 1.47–3.15), after adjusting for child ’s age and household’s wealth index. CONCLUSIONS: Anemia continues to be highly prevalent during pregnancy and early childhood in the Amazon. Public health policies should address iron deficiency, UPF intake, maternal anemia, and malaria in order to prevent and treat anemia in Amazonian children

Prevalence and predictors of breastfeeding in the MINA-Brazil cohort

OBJECTIVE: To describe the prevalence and factors associated with exclusive (EBF) and continued breastfeeding (BF) practices among Amazonian children. METHODS: Data from 1,143 mother-child pairs recorded on the Maternal and Child Health and Nutrition in Acre (MINA-Brazil) birth cohort were used. Information on EBF and BF was collected after childbirth (July 2015–June 2016) and during the follow-up visits at 1 and 6 months postpartum, 1, 2, and 5 years of age. For longitudinal analysis, the outcomes were EBF and BF duration. Probability of breastfeeding practices were estimated by Kaplan-Meier survival analysis. Associations between baseline predictors variables and outcomes among children born at term were assessed by extended Cox regression models. RESULTS: EBF frequencies (95% confidence interval [95%CI]) at 3 and 6 months of age were 33% (95%CI: 30.2–36.0) and 10.8% (95%CI: 8.9–12.9), respectively. Adjusted hazard ratio for predictors of early EBF cessation were: being a first-time mother = 1.47 (95%CI: 1.19–1.80), feeding newborns with prelacteals = 1.70 (95%CI: 1.23–2.36), pacifier use in the first week of life = 1.79 (95%CI: 1.44–2.23) or diarrhea in the first two weeks of life = 1.70 (95%CI: 1.15–2.52). Continued BF frequency was 67.9% (95%CI: 64.9–70.8), 29.3% (95%CI: 26.4–32.4), and 1.7% (95%CI: 0.9–2.8) at 1, 2 and 5 years of age, respectively. Adjusted hazard ratio for predictors of early BF cessation were: male sex = 1.23 (95%CI: 1.01–1.49), pacifier use in the first week of life = 4.66 (95%CI: 2.99–7.26), and EBF less than 3 months = 2.76 (95%CI: 1.64–4.66). CONCLUSIONS: EBF and continued BF duration among Amazonian children is considerably shorter than recommendations from the World Health Organization. Significant predictors of breastfeeding practices should be considered for evaluating local strategies to achieve optimal breastfeeding practices

Mortalidade neonatal: descrição e efeito do hospital de nascimento após ajuste de risco

OBJETIVO: Avaliar o efeito de hospital de nascimento na ocorrência de mortalidade neonatal. MÉTODOS: Uma coorte de nascimentos foi iniciada em Pelotas, em 2004. Todos os nascimentos hospitalares foram estudados em visitas diárias às maternidades da cidade, incluindo-se 4.558 recém-nascidos. As mães foram entrevistadas sobre fatores de risco em potencial e as mortes, monitoradas com visitas regulares aos hospitais, cemitérios e cartórios. Dois pediatras classificaram a causa básica da morte, de forma independente, a partir de informações obtidas no prontuário hospitalar e em entrevista com a família. Usou-se regressão logística para estimar o efeito do hospital de nascimento, controlando para variáveis de confusão relacionadas a características maternas e do recém-nascido. RESULTADOS: A taxa de mortalidade neonatal foi de 12,7. O risco esteve fortemente influenciado pelo peso ao nascer, idade gestacional e variáveis socioeconômicas. Imaturidade foi responsável por 65% das mortes neonatais, seguida por anomalias congênitas, infecções e asfixia intraparto. Ajustando para características maternas, foi observado um risco relativo igual a três para hospitais de mesmo nível de complexidade. O risco relativo diminuiu, mas persistiu, após controle para características do recém-nascido. CONCLUSÕES: A mortalidade neonatal variou entre hospitais e foi alta, principalmente relacionada à imaturidade. Para entender a fonte de variação da mortalidade neonatal e reduzir sua ocorrência é necessária uma avaliação aprofundada e comparativas com as práticas de cuidado entre hospitais.OBJECTIVE: To assess the effect of hospital of birth on neonatal mortality. METHODS: A birth cohort study was carried out in Pelotas, Southern Brazil, in 2004. All hospital births were assessed by daily visits to all maternity hospitals and 4558 deliveries were included in the study. Mothers were interviewed regarding potential risk factors. Deaths were monitored through regular visits to hospitals, cemeteries and register offices. Two independent pediatricians established the underlying cause of death based on information obtained from medical records and home visits to parents. Logistic regression was used to estimate the effect of hospital of birth, controlling for confounders related to maternal and newborn characteristics, according to a conceptual model. RESULTS: Neonatal mortality rate was 12.7 and it was highly influenced by birthweight, gestational age, and socioeconomic variables. Immaturity was responsible for 65% of neonatal deaths, followed by congenital anomalies, infections and intrapartum asphyxia. Adjusting for maternal characteristics, a three-fold increase in neonatal mortality was seen between similar complexity hospitals. The effect of hospital remained, though lower, after controlling for newborn characteristics. CONCLUSIONS: Neonatal mortality was high, mainly related to immaturity, and varied significantly across maternity hospitals. Further investigations comparing delivery care practices across hospitals are needed to better understand NMR variation and to develop strategies for neonatal mortality reduction