460 research outputs found

    Paisatges funeraris i diversitat a Anglaterra i a Gal·les: l'establiment d'una agenda = Deathscapes and diversity in England and Wales: setting an agenda

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    Aquest article se centra en una dimensió poc discutida, però important, de les experiències dels migrants i les minories a Anglaterra i Gal·les: els cementiris i crematoris de què disposen. Basat en una àmplia investigació amb comunitats locals i proveïdors de serveis en quatre ciutats casos d’estudi, aquest article ex-plora les diverses necessitats funeràries culturals i religioses a Anglaterra i Gal·les, els reptes que hi estan associats i les formes en què tant les comunitats com els proveïdors de serveis (p. ex.: planifica-dors i directors funeraris) hi responen. Destaquen vuit temes clau: i)l’oferta de cementiris; ii)l’oferta de crematoris; iii)l’oferta desigual per diferents grups migrants i minoritaris; iv)la diversitat en la diversitat; v)els canvis de patrons de repatriació;vi)el foment del diàleg;vii)la comprensió entre professionals icomunitats, i viii)la planificació dels cementiris com aespais de trobada.Este artículo se centra en una dimensión poco discutida pero importante de las experiencias de los migrantes y las mi-norías en Inglaterra y Gales: los cemen-terios y crematorios de que disponen. Basándose en una amplia investigación con comunidades locales y proveedores de servicios en cuatro ciudades casos de estudio, este artículo explora las diver-sas necesidades funerarias culturales y religiosas en Inglaterra y Gales, los retos asociados a estas y las formas en que tanto las comunidades como los provee-dores de servicios (p. ej.: planificadores y directores funerarios) responden a ellos. Destacan ocho temas clave: i)la oferta de cementerios; ii)la oferta de crematorios; iii)la oferta desigual por diferentes grupos migrantes y minoritarios; iv)la diversidad en la diversidad;v)los cambios de patrones de repatri-ación; vi)el fomento del diálogo;vii)la comprensión entre profesionalesy comunidades, y viii)la planificación de los cementerios como espacios de encuentro.This paper focuses on a little discussed but important dimension of migrant and minority experiences in England and Wales: cemetery and crematoria provi-sion. Based on extensive research with local communities and service providers in four case study towns, this paper explores the varied cultural and religious funerary needs in England and Wales, the associated challenges and the ways in which both communities and service providers (e.g. cemetery managers, town planners and funeral directors) respond to them. It highlights seven key themes, namely:i)cemetery provision;ii)crematorium provision;iii)unequal provision across migrantand minority groups;iv)diversity within diversity;v)changing patterns of repatriation; vi)fostering dialogue;vii)understanding between profession-als and communities; and viii)planning for cemeteries as spacesof encounter. / Este artículo se centra en una dimensión poco discutida pero importante de las experiencias de los migrantes y las mi-norías en Inglaterra y Gales: los cemen-terios y crematorios de que disponen. Basándose en una amplia investigación con comunidades locales y proveedores de servicios en cuatro ciudades casos de estudio, este artículo explora las diver-sas necesidades funerarias culturales y religiosas en Inglaterra y Gales, los retos asociados a estas y las formas en que tanto las comunidades como los provee-dores de servicios (p. ej.: planificadores y directores funerarios) responden a ellos. Destacan ocho temas clave: i)la oferta de cementerios; ii)la oferta de crematorios; iii)la oferta desigual por diferentes grupos migrantes y minoritarios; iv)la diversidad en la diversidad;v)los cambios de patrones de repatri-ación; vi)el fomento del diálogo;vii)la comprensión entre profesionalesy comunidades, y viii)la planificación de los cementerios como espacios de encuentro. / This paper focuses on a little discussed but important dimension of migrant and minority experiences in England and Wales: cemetery and crematoria provi-sion. Based on extensive research with local communities and service providers in four case study towns, this paper explores the varied cultural and religious funerary needs in England and Wales, the associated challenges and the ways in which both communities and service providers (e.g. cemetery managers, town planners and funeral directors) respond to them. It highlights seven key themes, namely:i)cemetery provision;ii)crematorium provision;iii)unequal provision across migrantand minority groups;iv)diversity within diversity;v)changing patterns of repatriation; vi)fostering dialogue;vii)understanding between profession-als and communities; and viii)planning for cemeteries as spacesof encounter

    Oscillatory surface rheotaxis of swimming E. coli bacteria

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    Bacterial contamination of biological conducts, catheters or water resources is a major threat to public health and can be amplified by the ability of bacteria to swim upstream. The mechanisms of this rheotaxis, the reorientation with respect to flow gradients, often in complex and confined environments, are still poorly understood. Here, we follow individual E. coli bacteria swimming at surfaces under shear flow with two complementary experimental assays, based on 3D Lagrangian tracking and fluorescent flagellar labelling and we develop a theoretical model for their rheotactic motion. Three transitions are identified with increasing shear rate: Above a first critical shear rate, bacteria shift to swimming upstream. After a second threshold, we report the discovery of an oscillatory rheotaxis. Beyond a third transition, we further observe coexistence of rheotaxis along the positive and negative vorticity directions. A full theoretical analysis explains these regimes and predicts the corresponding critical shear rates. The predicted transitions as well as the oscillation dynamics are in good agreement with experimental observations. Our results shed new light on bacterial transport and reveal new strategies for contamination prevention.Comment: 12 pages, 5 figure

    Impregnation of bone chips with alendronate and cefazolin, combined with demineralized bone matrix: a bone chamber study in goats

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    Contains fulltext : 108265.pdf (publisher's version ) (Open Access)BACKGROUND: Bone grafts from bone banks might be mixed with bisphosphonates to inhibit the osteoclastic response. This inhibition prevents the osteoclasts to resorb the allograft bone before new bone has been formed by the osteoblasts, which might prevent instability. Since bisphosphonates may not only inhibit osteoclasts, but also osteoblasts and thus bone formation, we studied different bisphosphonate concentrations combined with allograft bone. We investigated whether locally applied alendronate has an optimum dose with respect to bone resorption and formation. Further, we questioned whether the addition of demineralized bone matrix (DBM), would stimulate bone formation. Finally, we studied the effect of high levels of antibiotics on bone allograft healing, since mixing allograft bone with antibiotics might reduce the infection risk. METHODS: 25 goats received eight bone conduction chambers in the cortical bone of the proximal medial tibia. Five concentrations of alendronate (0, 0.5 mg/mL, 1 mg/mL, 2 mg/mL, and 10 mg/mL) were tested in combination with allograft bone and supplemented with cefazolin (200 mug/mL). Allograft not supplemented with alendronate and cefazolin served as control. In addition, allograft mixed with demineralized bone matrix, with and without alendronate, was tested. After 12 weeks, graft bone area and new bone area were determined with manual point counting. RESULTS: Graft resorption decreased significantly (p < 0.001) with increasing alendronate concentration. The area of new bone in the 1 mg/mL alendronate group was significantly (p = 0.002) higher when compared to the 10 mg/mL group. No differences could be observed between the group without alendronate, but with demineralized bone, and the control groups. CONCLUSIONS: A dose-response relationship for local application of alendronate has been shown in this study. Most new bone was present at 1 mg/mL alendronate. Local application of cefazolin had no effect on bone remodelling

    Prenatal diagnosis of a trisomy 7/trisomy 13 mosaicism

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    Double aneuploidy mosaicism of two different aneuploidy cell lines is rare. We describe for the first time a double trisomy mosaicism, involving chromosomes 7 and 13 in a fetus presenting with multiple congenital anomalies. No evidence for chimerism was found by DNA genotyping. The origin of both trisomies are consistent with isodisomy of maternal origin. Therefore, it is most likely that the double trisomy mosaicism arose from two independent events very early in embryonic development. The trisomy 7 and 13 cells were shown to be of maternal origin

    Potential merits for space robotics from novel concepts of actuation for soft robotics

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    Autonomous robots in dynamic and unstructured environments require high performance, energy efficient and reliable actuators. In this paper we give an overview of the first results of two lines of research regarding the novel actuation principle we introduced: Series-Parallel Elastic Actuation (SPEA). Firstly, we introduce the SPEA concept and present first prototypes and results. Secondly, we discuss the potential of self-healing materials in robotics, and discuss the results on the first self-healing pneumatic cell and selfhealing mechanical fuse. Both concepts have the potential to improve performance, energy efficiency and reliability

    A radiostereometric and clinical long-term follow-up study of the surface replacement trapeziometacarpal joint prosthesis

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    Background The aim of this study was to determine long-term survival and clinical outcomes of the surface replacement trapeziometacarpal joint prosthesis (SR (TM) TMC) and to evaluate implant migration using radiostereometric analysis (RSA).MethodsIn this clinical long-term follow-up study outcomes of ten patients who received the SR (TM) TMC joint prosthesis were evaluated using DASH and Nelson scores, Visual Analogue Scale (VAS) of pain, and key pinch strength. RSA-radiographs were obtained direct postoperatively and 6months, 1, 5 and 10years postoperatively and were analyzed using model-based RSA software.ResultsDuring follow-up, two early revisions took place. Mean pre-operative DASH and Nelson scores were 54 (SD 15) and 54 (SD 17), improved significantly after 6months (DASH 25 (SD 20), Nelson 75 (SD 18)) and remained excellent during long-term follow-up in all patients with a stable implant. At final follow-up, clinical scores deteriorated clearly in two patients with a loose implant in situ.ConclusionsLong-term survival of the SR (TM) TMC joint prosthesis is relatively poor. However, clinical outcomes improved significantly in the short-term and remained excellent in the long-term in those patients with a stable implant, but deteriorated clearly in case of loosening. The role of RSA in TMC joint arthroplasty is potentially valuable but needs to be further investigated. Several challenges of RSA in the TMC joint have been addressed by the authors and suggestions to optimize RSA-data are given.Trial registrationThis study was registered in the Netherlands Trial Register (NL7126).Orthopaedics, Trauma Surgery and Rehabilitatio
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