Indução de haploides em milho tropical superdoce e determinação de ploidia no estágio de plântulas

The objective of this work was to determine the possibility of haploid induction in tropical supersweet corn (Zea mays L. var. saccharata) using a maternal inducer, as well as to identify alternative methods for haploid selection. A single-cross hybrid of field corn and 11 tropical supersweet corn populations were crossed with the haploid inducer. The haploids were pre-selected using the R1-navajo marker and were differentiated into haploids or false positives at the V2–V3 stage, based on the color of the first leaf sheath and on the length of stomata guard cells. The obtained results are indicative of the possibility of inducing maternal haploids in populations of tropical supersweet corn. However, a large number of false-positive haploids were incorrectly selected by the R1-navajo marker. The color of the first leaf sheath was efficient for haploid identification in supersweet corn populations, and the method based on stomata morphometry can be used when there is no color distinction on the first leaf sheath.O objetivo deste trabalho foi verificar a possibilidade de indução de haploidia em milho superdoce tropical (Zea mays L. var. saccharata) por meio de indutor maternal, bem como identificar métodos alternativos para seleção de haploides. Um híbrido simples de milho comum e 11 populações de milho superdoce tropical foram cruzados com o indutor de haploidia. Os haploides foram pré-selecionados pelo marcador R1-navajo e diferenciados em haploides ou falsos positivos, no estágio V2–V3, com base na cor da primeira bainha foliar e no comprimento das células-guarda dos estômatos foliares. Os resultados obtidos são indicativos da possibilidade de induzir haploides maternos em populações de milho superdoce tropical. Contudo, muitos haploides falso-positivos foram selecionados incorretamente pelo marcador R1-navajo. A coloração da primeira bainha foliar foi eficiente na identificação de haploides em populações de milho superdoce, e o método baseado na morfometria dos estômatos pode ser usado quando não há distinção de cor da primeira bainha foliar

Influence of pre-milling of Cr3C2-25 NiCr spray powder on the fatigue life of HVOF-sprayed coating on ASTM A516 steel substrate

The aim of the present investigation is to evaluate the influence of the powder size of Cr3C2-25NiCr spraying powder on the fatigue behavior of HVOF-sprayed coating on the ASTM A516 steel substrate. Conventional commercial Cr3C2-25NiCr spraying powder was previously treated through high-energy milling. The crystallite sizes of milled powders were measured by X-ray diffraction and transmission electronic microscopy. Three different powder formats of the same Cr3C2-25NiCr composite were subjected to HVOF spraying to produce (i) a Milled-Coating (from high-energy milled spray powder), (ii) an Original-Coating (from conventional commercial spray powder), and (iii) a 50%–50% mixture of both (Milled + Original-Coating). The same spraying conditions were adopted for all the assessed cases. The sprayed coatings were investigated through the Knoop hardness test and SEM-EDS analysis. In addition, 3-point bending fatigue tests were conducted at different stress levels up to 107 cycles. The coating morphology and roughness effects on fatigue behavior were analyzed. The Cr3C2-25NiCr milled coating presented a lower fatigue life above the fatigue limit and a higher fatigue limit than other coatings; this outcome could be attributed to its lower surface roughness and finer grain size microstructure

Continuous results-driven innovation management program

Purpose – The purpose of this paper is to present the innovation management program (IMP) (FAZ Program) and analyze its results according to the public policy goals that support it (Pró-Inova) suggesting improvements. Design/methodology/approach – Intensive-direct-observation method in 43 companies; systematic data gathering and analysis (172 meeting documents); and innovation maturity diagnostics in 30 companies between August 2013 and May 2016. Findings – The FAZ Program success rate according to the Pró-Inova goals achieved 81 percent. The percentage of completion of FAZ activities decreases during its implementation from 100 percent (strategic module) to 74 percent (management module) and ending at 46 percent (project module). The maturity for innovation of these committees/teams is decisive for those percentages. Companies whose maturity for innovation of the strategic committee and the organizational team are above average or excellent have, respectively, 1.8 and 1.7 times greater probability of implementing the program successfully. Research limitations/implications – The FAZ Program represents only 4 percent of the programs supported by Pró-Inova. The innovative products, processes and businesses produced by the FAZ Program implementation are not measured. These innovations usually happen several years after an innovative management models implementation. Practical implications – The maturity for innovation diagnosis is useful both to evaluate the company’s innovation capacity and to predict its chances of implementing the program successfully. Adjusting the structure of the model (e.g. PDCA cycle for the organizational module) and improving the program’s implementation (e.g. ensure management module resources and maturity for innovation capacity) can increase the program’s success rate. Originality/value – Previous research works on IMPs supported by Pro-Inova focus on describing their methodology or benefits. The results allow answering what and how one of these programs offers in a return to the public innovation support received

A Educação Infantil na BNCC: desafios à consolidação de direitos de aprendizagem e desenvolvimento

ABSTRACT. This study addresses some theoretical and practical implications of the National Common Curricular Base (BNCC) for the development of pedagogical work in the field of early childhood education. Starting from an analysis of the state of the art with regard to the difficulties of teachers and students for educational action in this instance of basic education, it indicates elements for the debate that are aimed at explaining the problems listed and forwarding a process of constitution of learning subjects in early childhood education. This is a bibliographical research and documental analysis whose results show the difficulties of the basic school culture for overcoming the handling of didactic situations still strongly marked by the disregard of cultural diversity, by the association of models and by the dichotomy between caring and educating. It points to the theoretical construct of the cultural-historical perspective as a search for guidance for the realization of a broad process of production of meanings and negotiation of meanings of teaching and learning, in general, and Mathematics, in particular.ABSTRACT. This study addresses some theoretical and practical implications of the National Common Curricular Base (BNCC) for the development of pedagogical work in the field of early childhood education. Starting from an analysis of the state of the art with regard to the difficulties of teachers and students for educational action in this instance of basic education, it indicates elements for the debate that are aimed at explaining the problems listed and forwarding a process of constitution of learning subjects in early childhood education. This is a bibliographical research and documental analysis whose results show the difficulties of the basic school culture for overcoming the handling of didactic situations still strongly marked by the disregard of cultural diversity, by the association of models and by the dichotomy between caring and educating. It points to the theoretical construct of the cultural-historical perspective as a search for guidance for the realization of a broad process of production of meanings and negotiation of meanings of teaching and learning, in general, and Mathematics, in particular.RESUMEN. Este estudio aborda algunas implicaciones teóricas y prácticas de la Base Curricular Común Nacional (BNCC) para el desarrollo del trabajo pedagógico en el campo de la educación infantil. A partir de un análisis del estado del arte en cuanto a las dificultades de docentes y estudiantes para la acción educativa en esta instancia de educación básica, se señalan elementos para el debate que se orientan a esclarecer los problemas enumerados y adelantar un proceso de constitución de materias de aprendizaje en educación infantil. Se trata de una investigación bibliográfica y análisis documental cuyos resultados muestran las dificultades de la cultura escolar básica para superar el manejo de situaciones didácticas aún fuertemente marcadas por el desconocimiento de la diversidad cultural, por la asociación de modelos y por la dicotomía entre cuidar y educar. Apunta al constructo teórico de la perspectiva histórico-cultural como búsqueda de orientaciones para la realización de un amplio proceso de producción de sentidos y negociación de sentidos de la enseñanza y el aprendizaje, en general, y de las Matemáticas, en particular.ABSTRACT. This study addresses some theoretical and practical implications of the National Common Curricular Base (BNCC) for the development of pedagogical work in the field of early childhood education. Starting from an analysis of the state of the art with regard to the difficulties of teachers and students for educational action in this instance of basic education, it indicates elements for the debate that are aimed at explaining the problems listed and forwarding a process of constitution of learning subjects in early childhood education. This is a bibliographical research and documental analysis whose results show the difficulties of the basic school culture for overcoming the handling of didactic situations still strongly marked by the disregard of cultural diversity, by the association of models and by the dichotomy between caring and educating. It points to the theoretical construct of the cultural-historical perspective as a search for guidance for the realization of a broad process of production of meanings and negotiation of meanings of teaching and learning, in general, and Mathematics, in particular.O presente estudo aborda algumas implicações teórico-práticas da Base Nacional Comum Curricular (BNCC) para o desenvolvimento do trabalho pedagógico no âmbito da educação infantil. Partindo de uma análise sobre o estado da arte no que se refere às dificuldades de professores e alunos para a ação educativa nessa instância da educação básica, indica elementos ao debate que se voltam à explicação dos problemas elencados e para encaminhamento de um processo de constituição de sujeitos de aprendizagem na educação infantil. Trata-se de pesquisa bibliográfica e de análise documental cujos resultados mostram as dificuldades da cultura escolar básica para a superação do encaminhamento de situações didáticas ainda fortemente marcadas pela desconsideração da diversidade cultural, pela associação de modelos e pela dicotomia entre cuidar e educar. Aponta para o constructo teórico da perspectiva histórico-cultural como busca de encaminhamento para a efetivação de um amplo processo de produção de sentidos e de negociação de significados de ensino e de aprendizagem, de forma geral, e da Matemática, em particular. Palavras-chave: educação infantil, BNCC, formação de conceitos, produção de sentidos, negociação de significados.   Early Childhood Education at BNCC: challenges to the consolidation of learning and development rights ABSTRACT. This study addresses some theoretical and practical implications of the National Common Curricular Base (BNCC) for the development of pedagogical work in the field of early childhood education. Starting from an analysis of the state of the art with regard to the difficulties of teachers and students for educational action in this instance of basic education, it indicates elements for the debate that are aimed at explaining the problems listed and forwarding a process of constitution of learning subjects in early childhood education. This is a bibliographical research and documental analysis whose results show the difficulties of the basic school culture for overcoming the handling of didactic situations still strongly marked by the disregard of cultural diversity, by the association of models and by the dichotomy between caring and educating. It points to the theoretical construct of the cultural-historical perspective as a search for guidance for the realization of a broad process of production of meanings and negotiation of meanings of teaching and learning, in general, and Mathematics, in particular. Keywords: early childhood education, BNCC, concept formation, production of senses, negotiation of meanings.   Educación Infantil en la BNCC: desafíos para la consolidación de los derechos de aprendizaje y desarrollo RESUMEN. Este estudio aborda algunas implicaciones teóricas y prácticas de la Base Curricular Común Nacional (BNCC) para el desarrollo del trabajo pedagógico en el campo de la educación infantil. A partir de un análisis del estado del arte en cuanto a las dificultades de docentes y estudiantes para la acción educativa en esta instancia de educación básica, se señalan elementos para el debate que se orientan a esclarecer los problemas enumerados y adelantar un proceso de constitución de materias de aprendizaje en educación infantil. Se trata de una investigación bibliográfica y análisis documental cuyos resultados muestran las dificultades de la cultura escolar básica para superar el manejo de situaciones didácticas aún fuertemente marcadas por el desconocimiento de la diversidad cultural, por la asociación de modelos y por la dicotomía entre cuidar y educar. Apunta al constructo teórico de la perspectiva histórico-cultural como búsqueda de orientaciones para la realización de un amplio proceso de producción de sentidos y negociación de sentidos de la enseñanza y el aprendizaje, en general, y de las Matemáticas, en particular. Palabras clave: educación infantil, BNCC, formación de conceptos, producción de sentidos, negociación de significados

Bovine leukemia viral DNA found on human breast tissue is genetically related to the cattle virus

Bovine leukemia virus (BLV) infection is widespread in cattle and associated with B cell lymphoma. In a previousstudy we demonstrated that bovine leukemia viral DNA was detected in human breast tissues and significantly associated with breast cancer. Our current study aimed to determine whether BLV DNA found in humans and cattle at the same geographical region were genetically related. DNA was extracted from the breast tissue of healthy (n = 32) or cancerous women patients (n = 27) and from the blood (n = 30) of cattle naturally infected with BLV, followed by PCR-amplification and partial nucleotide sequencing of the BLV env gene. We found that the nucleotide sequence identity between BLV env gene fragments obtained from human breast tissue and cattle blood ranged from 97.8 to 99.7% and grouped into genotype 1. Thus, our results further support the hypothesis that this virus might cause a zoonotic infection

Mortalidade por doença renal crônica secundária à hipertensão no Brasil: um estudo do “Global Burden of Disease”

Background and Objectives: Chronic kidney disease (CKD) is one of the main complications resulting from arterial hypertension, and a recent increase in the incidence and prevalence of the disease has been reported, which can lead to an increase in mortality and complications resulting from the disease. Thus, the objective of study is to describe the variations in mortality from CKD secondary to arterial hypertension, in Brazil, between the years 1990 to 2019. Methods: Epidemiological study, with a quantitative approach and descriptive character, which analyzed data from the “Global Burden of Disease Study” (GBD) tool. Results: In all of Brazil’s federative units, the estimate of deaths from CKD secondary to hypertension increased, with the Southeast region having the highest estimates. The States of Rio de Janeiro, Rio Grande do Sul, and Paraíba lead with the highest mortality rates. Regarding sex, in all years, higher rates were observed in males, however, over the years, this difference has been reduced. The age group of ≥70 years was the most affected, standing out with the highest death rates. Conclusion: the burden of CKD in Brazil has increased in the last 30 years; among the regions of the country, the Southeast recorded the highest estimates of deaths in all the years analyzed, being mainly higher among men.Justificación y objetivos: La enfermedad renal crónica (ERC) es una de las principales complicaciones derivadas de la hipertensión arterial, y en los últimos años se ha reportado un aumento en la incidencia y prevalencia de la enfermedad, lo que puede conducir a un aumento de la mortalidad y de las complicaciones derivadas de esta, por lo tanto, el objetivo del estudio es describir las variaciones en la mortalidad por ERC secundaria a la hipertensión arterial en Brasil entre los años 1990 a 2019. Métodos: Estudio epidemiológico, con enfoque cuantitativo y carácter descriptivo, que analizó datos de la herramienta Global Burden of Disease Study (GBD). Resultados: En todas las unidades de la federación, aumentó la estimación de muertes por ERC secundaria a la hipertensión arterial, con la región Sudeste presentando las estimaciones más altas. Los estados de Rio de Janeiro, Rio Grande do Sul y Paraíba lideran con las tasas de mortalidad más altas. Con respecto al sexo, en todos los años se observaron mayores tasas en los varones, sin embargo, con el paso de los años, esta diferencia se ha ido reduciendo. El grupo de edad de ≥70 años fue el más afectado, destacándose con las tasas de mortalidad más altas. Conclusión: la carga de ERC en Brasil ha aumentado en los últimos 30 años; de las regiones del país, el Sudeste registró las mayores estimaciones de muertes en todos los años registrados entre los analizados, siendo principalmente mayor entre los hombres.Justificativa e objetivos: A doença renal crônica (DRC) é uma das principais complicações decorrentes da hipertensão arterial. Nos últimos anos, tem sido relatado um aumento na incidência e prevalência da doença, o que pode levar ao aumento da mortalidade e das complicações decorrentes da doença. Assim, o objetivo deste estudo foi descrever as variações da mortalidade por DRC secundária à hipertensão arterial no Brasil entre 1990 e 2019. Métodos: Trata-se de um estudo epidemiológico, de abordagem quantitativa e caráter descritivo, que analisou dados da ferramenta Global Burden of Disease Study (GBD). Resultados: Em todas as unidades da federação, a estimativa de mortes por DRC secundária à hipertensão apresentou aumento, a região Sudeste apresentando as maiores estimativas. Os estados do Rio de Janeiro, Rio Grande do Sul e Paraíba lideram as pesquisas com as maiores taxas de mortalidade. No que diz respeito ao sexo, em todos os anos foram observadas maiores taxas de DRC em indivíduos do sexo masculino; contudo, nota-se que tem ocorrido uma redução dessa diferença. A faixa etária de ≥70 anos foi a mais acometida, destacando-se com as maiores taxas de mortes. Conclusão: a carga de DRC no Brasil aumentou nos últimos 30 anos. Entre as regiões do país, o Sudeste registrou as maiores estimativas de mortes em todos os anos analisados, principalmente de homens

Caracterização de rejeito aluvionar de minério de ouro da região de Peixoto de Azevedo (mt)

A extração de ouro nos garimpos, que na maioria das vezes é feita de forma rudimentar (apenas por gravimetria), não garante a obtenção de um bom rendimento, o que gera rejeitos (curimã) com alto teor de minério (ouro). Visando a melhoria no estado da arte do processamento de minérios aluvionares, este estudo de caso visa caracterizar o rejeito do Garimpo Jatobá no vale do rio Peixoto de Azevedo, através de ensaios de concentração gravimétrica, análises granulométrica e química. O método adotado foi a coleta do material direto no garimpo através de um trado, elaboração de curva granulométrica (método Rosin-Rammler), peneiramento, separação de amostras e a análise físico/química de onde foram obtidos os diversos teores de ouro presentes em cada amostra e plotado um quadro comparativo.Peer ReviewedObjectius de Desenvolupament Sostenible::9 - Indústria, Innovació i InfraestructuraPostprint (published version