WHICH RETAIL FOOD SERVICES ARE CONSUMERS WILLING TO DO WITHOUT

Consumer/Household Economics,

Modal analysis computer program package

Modal analysis computer program package for finding frequencies and mode shapes of any linear discrete system governed by generalized eigenvalue equatio

Validity of resting heart rate derived from contact-based smartphone photoplethysmography compared with electrocardiography:a scoping review and checklist for optimal acquisition and reporting

Background: With the rise of smartphone ownership and increasing evidence to support the suitability of smartphone usage in healthcare, the light source and smartphone camera could be utilized to perform photoplethysmography (PPG) for the assessment of vital signs, such as heart rate (HR). However, until rigorous validity assessment has been conducted, PPG will have limited use in clinical settings.Objective: We aimed to conduct a scoping review assessing the validity of resting heart rate (RHR) acquisition from PPG utilizing contact-based smartphone devices. Our four specific objectives of this scoping review were to (1) conduct a systematic search of the published literature concerning contact-based smartphone device-derived PPG, (2) map study characteristics and methodologies, (3) identify if methodological and technological advancements have been made, and (4) provide recommendations for the advancement of the investigative area.Methods: ScienceDirect, PubMed and SPORTDiscus were searched for relevant studies between January 1st, 2007, and November 6th, 2022. Filters were applied to ensure only literature written in English were included. Reference lists of included studies were manually searched for additional eligible studies.Results: In total 10 articles were included. Articles varied in terms of methodology including study characteristics, index measurement characteristics, criterion measurement characteristics, and experimental procedure. Additionally, there were variations in reporting details including primary outcome measure and measure of validity. However, all studies reached the same conclusion, with agreement ranging between good to very strong and correlations ranging from r = .98 to 1.Conclusions: Smartphone applications measuring RHR derived from contact-based smartphone PPG appear to agree with gold standard electrocardiography (ECG) in healthy subjects. However, agreement was established under highly controlled conditions. Future research could investigate their validity and consider effective approaches that transfer these methods from laboratory conditions into the “real-world”, in both healthy and clinical populations

Submillimeter wavelength survey of the galactic plane from l = -5 deg to l = +62 deg: Structure and energetics of the inner disk

Results from a large scale survey of the first quadrant of the Milky Way galactic plane at wavelengths of 150, 250, and 300 microns with a 10x10 arcmin beam are presented. The emission detected in the survey arises from compact sources, most of which are identified with known peaks of 5 GHz and/or CO emission, and from an underlying diffuse background with a typical angular width of approximately 0.9 deg (FWHM) which accounts for most of the emission. A total of 80 prominent discrete sources were identified and characterized, of which about half were not previously reported at far infrared wavelengths. The total infrared luminosity within the solar circle is approximately 1 to 2x10 to the 10th power L sub 0, and is probably emitted by dust that resides in molecular clouds

Comparison of the COBE FIRAS and DIRBE Calibrations

We compare the independent FIRAS and DIRBE observations from the COBE in the wavelength range 100-300 microns. This cross calibration provides checks of both data sets. The results show that the data sets are consistent within the estimated gain and offset uncertainties of the two instruments. They show the possibility of improving the gain and offset determination of DIRBE at 140 and 240 microns.Comment: Accepted for publication in the Astrophysical Journal 11 pages, plus 3 figures in separate postscript files. Figure 3 has three part

A new kind of Lax-Oleinik type operator with parameters for time-periodic positive definite Lagrangian systems

In this paper we introduce a new kind of Lax-Oleinik type operator with parameters associated with positive definite Lagrangian systems for both the time-periodic case and the time-independent case. On one hand, the new family of Lax-Oleinik type operators with an arbitrary $u\in C(M,\mathbb{R}^1)$ as initial condition converges to a backward weak KAM solution in the time-periodic case, while it was shown by Fathi and Mather that there is no such convergence of the Lax-Oleinik semigroup. On the other hand, the new family of Lax-Oleinik type operators with an arbitrary $u\in C(M,\mathbb{R}^1)$ as initial condition converges to a backward weak KAM solution faster than the Lax-Oleinik semigroup in the time-independent case.Comment: We give a new definition of Lax-Oleinik type operator; add some reference

Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery

Background Neuroblastoma is a paediatric cancer that despite multimodal therapy still has a poor outcome for many patients with high risk tumours. Retinoic acid (RA) promotes differentiation of some neuroblastoma tumours and cell lines, and is successfully used clinically, supporting the view that differentiation therapy is a promising strategy for treatment of neuroblastoma. To improve treatment of a wider range of tumour types, development and testing of novel differentiation agents is essential. New pre-clinical models are therefore required to test therapies in a rapid cost effective way in order to identify the most useful agents. Methods As a proof of principle, differentiation upon ATRA treatment of two MYCN-amplified neuroblastoma cell lines, IMR32 and BE2C, was measured both in cell cultures and in tumours formed on the chick chorioallantoic membrane (CAM). Differentiation was assessed by 1) change in cell morphology, 2) reduction in cell proliferation using Ki67 staining and 3) changes in differentiation markers (STMN4 and ROBO2) and stem cell marker (KLF4). Results were compared to MLN8237, a classical Aurora Kinase A inhibitor. For the in vivo experiments, cells were implanted on the CAM at embryonic day 7 (E7), ATRA treatment was between E11 and E13 and tumours were analysed at E14. Results Treatment of IMR32 and BE2C cells in vitro with 10 μM ATRA resulted in a change in cell morphology, a 65% decrease in cell proliferation, upregulation of STMN4 and ROBO2 and downregulation of KLF4. ATRA proved more effective than MLN8237 in these assays. In vivo, 100 μM ATRA repetitive treatment at E11, E12 and E13 promoted a change in expression of differentiation markers and reduced proliferation by 43% (p < 0.05). 40 μM ATRA treatment at E11 and E13 reduced proliferation by 37% (p < 0.05) and also changed cell morphology within the tumour. Conclusion Differentiation of neuroblastoma tumours formed on the chick CAM can be analysed by changes in cell morphology, proliferation and gene expression. The well-described effects of ATRA on neuroblastoma differentiation were recapitulated within 3 days in the chick embryo model, which therefore offers a rapid, cost effective model compliant with the 3Rs to select promising drugs for further preclinical analysis

Effect of Prolonged Sitting and Breaks in Sitting Time on Endothelial Function

Sitting time (ST) is associated with cardiovascular disease risk factors, whereas breaking ST has been reported to be beneficial for reducing cardiovascular risk. Purpose: The objective of this study is to examine the effects of breaking ST on superficial femoral artery (SFA) endothelial function. Hypotheses: 1) Prolonged sitting would induce endothelial dysfunction and changes in shear forces, and 2) breaking ST with brief periods of activity would prevent attenuation in endothelial function. Methods: Twelve nonobese men (24.2 ± 4.2 yr) participated in two randomized 3-h sitting trials. In the sitting (SIT) trial, subjects were seated on a firmly cushioned chair for 3 h without moving their lower extremities. In the breaking ST trial (ACT), subjects sat similar to the SIT trial but walked on a treadmill for 5 min at 2 mph at 30 min, 1 h 30 min, and 2 h 30 min during the sitting interval. SFA flow-mediated dilation (FMD) was assessed at baseline, 1 h, 2 h, and 3 h in each trial. Statistical analyses were performed using dependent variables SFA FMD and shear rates. Significance was set at P ≤ 0.05. Results: In the SIT trial, there was a significant decline in SFA FMD from baseline to 3 h (baseline, 4.72% ± 3.78%; 1 h, 0.52% ± 0.85%; 2 h, 1.66% ± 1.11%; 3 h, 2.2% ± 2.15; P < 0.05 by ANOVA) accompanied by a decline in mean shear rate and antegrade shear rate but no difference in shear rate (area under the curve). By two-way repeated-measures ANOVA, ACT prevented the sitting-induced decline in FMD (baseline, 4.5% ± 2.3%; 1 h, 5.04% ± 2.85%; 2 h, 5.28% ± 5.05%; 3 h, 6.9% ± 4.5%) along with no decline in shear rates. Conclusion: Three hours of sitting resulted in a significant impairment in shear rate and SFA FMD. When light activity breaks were introduced hourly during sitting, the decline in FMD was prevented